Patrick Bulau

Affiliations
  • Pharma Technical Development, Hoffmann-La Roche, 4070 Basel, Switzerland.
ORCID: 0000-0002-7121-2954

Publications (10)

Comprehensive Multidimensional Liquid Chromatography-Mass Spectrometry for the Characterization of Charge Variants of a Bispecific Antibody.

Journal of the American Society for Mass Spectrometry
Avec: Ingrid Grunert , Katrin Heinrich , Michael Hingar , Juliane Ernst , Martin Winter , Katrin Bomans , Katharina Wagner , Arnaud Fevre , Dietmar Reusch , Manfred Wuhrer , Patrick Bulau

Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry.

Analytical chemistry
Avec: Felix Kuhne , Katrin Heinrich , Martin Winter , Jürgen Fichtl , Gabriel Hoffmann , Franziska Zähringer , Katharina Spitzauer , Monika Meier , Tarik A Khan , Lea Bonnington , Katharina Wagner , Jan Olaf Stracke , Dietmar Reusch , Harald Wegele , Michael Mormann , Patrick Bulau

Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry.

Journal of the American Society for Mass Spectrometry
Avec: Markus Haberger , Anna-Katharina Heidenreich , Michaela Hook , Jürgen Fichtl , Rainer Lang , Florian Cymer , Mahdi Adibzadeh , Felix Kuhne , Harald Wegele , Dietmar Reusch , Lea Bonnington , Patrick Bulau

Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS.

Talanta
Avec: Julien Camperi , Ingrid Grunert , Katrin Heinrich , Martin Winter , Saban Özipek , Sina Hoelterhoff , Thomas Weindl , Kilian Mayr , Patrick Bulau , Monika Meier , Michael Mølhøj , Michael Leiss , Davy Guillarme , Anja Bathke , Cinzia Stella

Multi-Attribute Monitoring of Complex Erythropoetin Beta Glycosylation by GluC Liquid Chromatography-Mass Spectrometry Peptide Mapping.

Analytical chemistry
Avec: Alexander Buettner , Maria Maier , Lea Bonnington , Patrick Bulau , Dietmar Reusch

Recent advances in LC-MS based characterization of protein-based bio-therapeutics - mastering analytical challenges posed by the increasing format complexity.

Journal of pharmaceutical and biomedical analysis
Avec: Tobias Graf , Katrin Heinrich , Ingrid Grunert , Harald Wegele , Markus Haberger , Patrick Bulau , Michael Leiss

Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics.

mAbs
Avec: Oksana Tyshchuk , Christoph Gstöttner , Dennis Funk , Simone Nicolardi , Stefan Frost , Stefan Klostermann , Tim Becker , Elena Jolkver , Felix Schumacher , Claudia Ferrara Koller , Hans Rainer Völger , Manfred Wuhrer , Patrick Bulau , Michael Mølhøj

Detailed Analytical Characterization of a Bispecific IgG1 CrossMab Antibody of the Knob-into-Hole Format Applying Various Stress Conditions Revealed Pronounced Stability.

ACS omega
Avec: Ingrid Grunert , Katrin Heinrich , Juliane Ernst , Michael Hingar , Alexandre Briguet , Michael Leiss , Manfred Wuhrer , Dietmar Reusch , Patrick Bulau

The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange.

Antibodies (Basel, Switzerland)
Avec: Felix Kuhne , Lea Bonnington , Sebastian Malik , Marco Thomann , Cecile Avenal , Florian Cymer , Harald Wegele , Dietmar Reusch , Michael Mormann , Patrick Bulau

Quantifying methionine sulfoxide in therapeutic protein formulation excipients as sensitive oxidation marker.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Avec: Arnaud Fevre , Steffen Kiessig , Lea Bonnington , Jan Olaf Stracke , Patrick Bulau

Réseau de co-auteurs

Dietmar Reusch 6 collaborations
Katrin Heinrich 5 collaborations
Lea Bonnington 5 collaborations
Ingrid Grunert 4 collaborations
Harald Wegele 4 collaborations
Martin Winter 3 collaborations
Manfred Wuhrer 3 collaborations
Felix Kuhne 3 collaborations
Michael Leiss 3 collaborations
Michael Hingar 2 collaborations
Juliane Ernst 2 collaborations
Katharina Wagner 2 collaborations
Arnaud Fevre 2 collaborations
Jürgen Fichtl 2 collaborations
Monika Meier 2 collaborations
Jan Olaf Stracke 2 collaborations
Michael Mormann 2 collaborations
Markus Haberger 2 collaborations
Florian Cymer 2 collaborations
Michael Mølhøj 2 collaborations
Katrin Bomans 1 collaboration
Gabriel Hoffmann 1 collaboration
Franziska Zähringer 1 collaboration
Katharina Spitzauer 1 collaboration
Tarik A Khan 1 collaboration
Anna-Katharina Heidenreich 1 collaboration
Michaela Hook 1 collaboration
Rainer Lang 1 collaboration
Mahdi Adibzadeh 1 collaboration
Julien Camperi 1 collaboration
Saban Özipek 1 collaboration
Sina Hoelterhoff 1 collaboration
Thomas Weindl 1 collaboration
Kilian Mayr 1 collaboration
Davy Guillarme 1 collaboration
Anja Bathke 1 collaboration
Cinzia Stella 1 collaboration
Alexander Buettner 1 collaboration
Maria Maier 1 collaboration
Tobias Graf 1 collaboration
Oksana Tyshchuk 1 collaboration
Christoph Gstöttner 1 collaboration
Dennis Funk 1 collaboration
Simone Nicolardi 1 collaboration
Stefan Frost 1 collaboration
Stefan Klostermann 1 collaboration
Tim Becker 1 collaboration
Elena Jolkver 1 collaboration
Felix Schumacher 1 collaboration
Claudia Ferrara Koller 1 collaboration
Hans Rainer Völger 1 collaboration
Alexandre Briguet 1 collaboration
Sebastian Malik 1 collaboration
Marco Thomann 1 collaboration
Cecile Avenal 1 collaboration
Steffen Kiessig 1 collaboration