Davy Guillarme

Affiliations

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU, 1, Rue Michel Servet, 1211 Geneva 4, Switzerland.

Publications (100)

Utility of dry load injection for an efficient natural products isolation at the semi-preparative chromatographic scale.

Journal of chromatography. A

Avec: Emerson Ferreira Queiroz , Abdulelah Alfattani , Adlin Afzan , Laurence Marcourt , Davy Guillarme , Jean-Luc Wolfender

The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances.

Accounts of chemical research

Avec: Erik L Regalado , Imad A Haidar Ahmad , Raffeal Bennett , Valentina D'Atri , Alexey A Makarov , Guy R Humphrey , Ian Mangion , Davy Guillarme

Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study.

Journal of chromatography. A

Avec: Evelin Farsang , Krisztián Horváth , Alain Beck , Qi Wang , Matthew Lauber , Davy Guillarme , Szabolcs Fekete

From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies.

Journal of chromatography. A

Avec: Alexandre Goyon , Lu Dai , Tao Chen , Bingchuan Wei , Feng Yang , Nisana Andersen , Robert Kopf , Michael Leiss , Michael Mølhøj , Davy Guillarme , Cinzia Stella

Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices.

Journal of chromatography. A

Avec: Gioacchino Luca Losacco , Omar Ismail , Julian Pezzatti , Víctor González-Ruiz , Julien Boccard , Serge Rudaz , Jean-Luc Veuthey , Davy Guillarme

Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Jennifer M Nguyen , Xiaoxiao Liu , Maureen DeLoffi , Amarande Murisier , Szabolcs Fekete , Davy Guillarme , Matthew A Lauber

Fast Afucosylation Profiling of Glycoengineered Antibody Subunits by Middle-Up Mass Spectrometry.

Methods in molecular biology (Clifton, N.J.)

Avec: Elsa Wagner-Rousset , Olivier Colas , Stéphane Chenu , Yannis-Nicolas François , Davy Guillarme , Sarah Cianferani , Yury O Tsybin , Jonathan Sjögren , Arnaud Delobel , Alain Beck

Negative gradient slope methods to improve the separation of closely eluting proteins.

Journal of chromatography. A

Avec: Szabolcs Fekete , Amarande Murisier , Jennifer M Nguyen , Matthew A Lauber , Davy Guillarme

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography.

Analytical chemistry

Avec: Szabolcs Fekete , Amarande Murisier , Jennifer M Nguyen , Michael J Bolton , Jonathan Belanger , Alain Beck , Jean-Luc Veuthey , Kevin Wyndham , Matthew A Lauber , Davy Guillarme

Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Alexandre Goyon , Daniel McDonald , Szabolcs Fekete , Davy Guillarme , Cinzia Stella

Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of

Frontiers in chemistry

Avec: Léonie Pellissier , Alexey Koval , Laurence Marcourt , Emerson Ferreira Queiroz , Nicole Lecoultre , Sara Leoni , Luis-Manuel Quiros-Guerrero , Morgane Barthélémy , Bastiaan L Duivelshof , Davy Guillarme , Sébastien Tardy , Véronique Eparvier , Karl Perron , Jérôme Chave , Didier Stien , Katia Gindro , Vladimir Katanaev , Jean-Luc Wolfender

Empirical correction of non-linear pH gradients and a tool for application to protein ion exchange chromatography.

Journal of chromatography. A

Avec: Szabolcs Fekete , Amarande Murisier , Matthew Lauber , Davy Guillarme

Ion mobility-high resolution mass spectrometry in doping control analysis. Part II: Comparison of acquisition modes with and without ion mobility.

Analytica chimica acta

Avec: Kateřina Plachká , Julian Pezzatti , Alessandro Musenga , Raul Nicoli , Tiia Kuuranne , Serge Rudaz , Lucie Nováková , Davy Guillarme

Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale.

Angewandte Chemie (International ed. in English)

Avec: Imad A Haidar Ahmad , Gioacchino Luca Losacco , Vladimir Shchurik , Xiao Wang , Ryan D Cohen , Alastair N Herron , Sheenagh Aiken , Daniele Fiorito , Heather Wang , Mikhail Reibarkh , Timothy Nowak , Alexey A Makarov , Dwight R Stoll , Davy Guillarme , Ian Mangion , Varinder K Aggarwal , Jin-Quan Yu , Erik L Regalado

Theoretical and practical comparison of RPLC and RPLC × RPLC: how to consider dilution effects and sensitivity in addition to separation power?

Analytical and bioanalytical chemistry

Avec: Davy Guillarme , Florent Rouvière , Sabine Heinisch

Ultra-high performance supercritical fluid chromatography coupled to tandem mass spectrometry for antidoping analyses: Assessment of the inter-laboratory reproducibility with urine samples.

Analytical science advances

Avec: Gioacchino Luca Losacco , Marco Rentsch , Kateřina Plachká , Fabrice Monteau , Emmanuelle Bichon , Bruno Le Bizec , Lucie Nováková , Raul Nicoli , Tiia Kuuranne , Jean-Luc Veuthey , Davy Guillarme

A novel ultra-high-performance supercritical fluid chromatography hyphenated to tandem mass spectrometry method for the analysis of urinary endogenous steroids in the anti-doping context.

Journal of chromatography. A

Avec: Tobias Langer , Raul Nicoli , Davy Guillarme , Carine Schweizer-Grundisch , Serge Rudaz , Silke Grabherr , Tiia Kuuranne , Alessandro Musenga

[Biosimilar monoclonal antibodies: comparative study of analytical and functional quality].

Medecine sciences : M/S

Avec: Alain Beck , Davy Guillarme , Sandrine Fleury-Souverain , Elsa Bodier-Montagutelli , Renaud Respaud

Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies.

Analytical chemistry

Avec: Julien Camperi , Lu Dai , Davy Guillarme , Cinzia Stella

Development of a 3D-LC/MS Workflow for Fast, Automated, and Effective Characterization of Glycosylation Patterns of Biotherapeutic Products.

Analytical chemistry

Avec: Julien Camperi , Lu Dai , Davy Guillarme , Cinzia Stella

Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis.

Journal of pharmaceutical and biomedical analysis

Avec: Julien Camperi , Davy Guillarme , Ming Lei , Cinzia Stella

Analytical strategies for the determination of amino acids: Past, present and future trends.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Sabrina Ferré , Víctor González-Ruiz , Davy Guillarme , Serge Rudaz

Computer-assisted UHPLC-MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy.

Journal of pharmaceutical and biomedical analysis

Avec: Nicolas Guichard , Szabolcs Fekete , Davy Guillarme , Pascal Bonnabry , Sandrine Fleury-Souverain

Interlaboratory and Interplatform Study of Steroids Collision Cross Section by Traveling Wave Ion Mobility Spectrometry.

Analytical chemistry

Avec: Maykel Hernández-Mesa , Valentina D'Atri , Gitte Barknowitz , Mathieu Fanuel , Julian Pezzatti , Nicola Dreolin , David Ropartz , Fabrice Monteau , Evelyne Vigneau , Serge Rudaz , Sara Stead , Hélène Rogniaux , Davy Guillarme , Gaud Dervilly , Bruno Le Bizec

Expanding the range of sub/supercritical fluid chromatography: Advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis.

Journal of chromatography. A

Avec: Gioacchino Luca Losacco , Jimmy Oliviera DaSilva , Jinchu Liu , Erik L Regalado , Jean-Luc Veuthey , Davy Guillarme

The importance of being metal-free: The critical choice of column hardware for size exclusion chromatography coupled to high resolution mass spectrometry.

Analytica chimica acta

Avec: Amarande Murisier , Szabolcs Fekete , Davy Guillarme , Valentina D'Atri

Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins.

Journal of chromatography. A

Avec: Jose Antonio Navarro-Huerta , Amarande Murisier , Jennifer M Nguyen , Matthew A Lauber , Alain Beck , Davy Guillarme , Szabolcs Fekete

Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets.

Analytical and bioanalytical chemistry

Avec: Gioacchino Luca Losacco , Michael B Hicks , Jimmy O DaSilva , Heather Wang , Miraslava Potapenko , Fuh-Rong Tsay , Imad A Haidar Ahmad , Ian Mangion , Davy Guillarme , Erik L Regalado

Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method development.

Journal of pharmaceutical and biomedical analysis

Avec: Bastiaan Duivelshof , Arnold Zöldhegyi , Davy Guillarme , Matthew Lauber , Szabolcs Fekete

Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody.

Molecules (Basel, Switzerland)

Avec: Claire I Butré , Valentina D'Atri , Hélène Diemer , Olivier Colas , Elsa Wagner , Alain Beck , Sarah Cianferani , Davy Guillarme , Arnaud Delobel

Comprehensive evaluation of zwitterionic hydrophilic liquid chromatography stationary phases for oligonucleotide characterization.

Journal of chromatography. A

Avec: Honorine Lardeux , Davy Guillarme , Valentina D'Atri

High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns.

Analytical chemistry

Avec: Honorine Lardeux , Szabolcs Fekete , Matthew Lauber , Valentina D'Atri , Davy Guillarme

Theoretical and practical guidelines for solvent dilution between the two dimensions in online comprehensive two-dimensional liquid chromatography.

Journal of chromatography. A

Avec: Megane K Aebischer , Soraya Chapel , Davy Guillarme , Sabine Heinisch

Optimizing Messenger RNA Analysis Using Ultra-Wide Pore Size Exclusion Chromatography Columns.

International journal of molecular sciences

Avec: Valentina D'Atri , Honorine Lardeux , Alexandre Goyon , Mateusz Imiołek , Szabolcs Fekete , Matthew Lauber , Kelly Zhang , Davy Guillarme

Automated multicolumn screening workflow in ultra-high pressure hydrophilic interaction chromatography for streamlined method development of polar analytes.

Journal of chromatography. A

Avec: Mohamed Hemida , Rodell C Barrientos , Andrew N Singh , Gioacchino Luca Losacco , Heather Wang , Davy Guillarme , Eli Larson , Wei Xu , Emmanuel Appiah-Amponsah , Erik L Regalado

Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions.

Journal of chromatography. A

Avec: Gioacchino Luca Losacco , Elisa Marconetto , Raul Nicoli , Tiia Kuuranne , Julien Boccard , Serge Rudaz , Jean-Luc Veuthey , Davy Guillarme

Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins.

Analytical chemistry

Avec: Szabolcs Fekete , Alain Beck , Jean-Luc Veuthey , Davy Guillarme

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 1: Alternative mobile phases and fine tuning of the separation.

Journal of pharmaceutical and biomedical analysis

Avec: Evelin Farsang , Amarande Murisier , Krisztián Horváth , Alain Beck , Róbert Kormány , Davy Guillarme , Szabolcs Fekete

Streamlined Characterization of an Antibody-Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry.

Analytical chemistry

Avec: Alexandre Goyon , Michael Kim , Lu Dai , Christopher Cornell , Fred Jacobson , Davy Guillarme , Cinzia Stella

Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry.

Analytical chemistry

Avec: Valentina D'Atri , Lucie Nováková , Szabolcs Fekete , Dwight Stoll , Matthew Lauber , Alain Beck , Davy Guillarme

Apparent efficiency of serially coupled columns in gradient elution liquid chromatography: Extension to the combination of any column formats.

Journal of chromatography. A

Avec: Santiago Codesido , Serge Rudaz , Davy Guillarme , Krisztián Horváth , Szabolcs Fekete

Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical products.

Journal of chromatography. A

Avec: Szabolcs Fekete , Harald Ritchie , Jason Lawhorn , Jean-Luc Veuthey , Davy Guillarme

Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted Metabolomics.

Metabolites

Avec: Julian Pezzatti , Víctor González-Ruiz , Julien Boccard , Davy Guillarme , Serge Rudaz

Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches.

The Analyst

Avec: Julien Camperi , Alexandre Goyon , Davy Guillarme , Kelly Zhang , Cinzia Stella

Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MS.

Analytical chemistry

Avec: Julien Camperi , Davy Guillarme , Cinzia Stella

Investigating the use of unconventional temperatures in supercritical fluid chromatography.

Analytica chimica acta

Avec: Gioacchino Luca Losacco , Szabolcs Fekete , Jean-Luc Veuthey , Davy Guillarme

A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomolecules.

Journal of separation science

Avec: Davy Guillarme , Thomas Bouvarel , Florent Rouvière , Sabine Heinisch

Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies.

Journal of chromatography. A

Avec: Amarande Murisier , Bastiaan L Duivelshof , Szabolcs Fekete , Julien Bourquin , Andrew Schmudlach , Matthew A Lauber , Jennifer M Nguyen , Alain Beck , Davy Guillarme , Valentina D'Atri

Anion-Exchange Chromatography at the Service of Gene Therapy: Baseline Separation of Full/Empty Adeno-Associated Virus Capsids by Screening of Conditions and Step Gradient Elution Mode.

International journal of molecular sciences

Avec: Megane K Aebischer , Hugo Gizardin-Fredon , Honorine Lardeux , Dominik Kochardt , Carsten Elger , Markus Haindl , Raphael Ruppert , Davy Guillarme , Valentina D'Atri

Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute.

Pharmaceutics

Avec: Amarande Murisier , Valentina D'Atri , Sebastian Pirner , Vincent Larraillet , Szabolcs Fekete , Matthew Lauber , Davy Guillarme

Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levels.

Journal of pharmaceutical and biomedical analysis

Avec: S Fleury-Souverain , J Maurin , D Guillarme , S Rudaz , P Bonnabry

Tackling Issues Observed during the Development of a Liquid Chromatography Method for Small Molecule Quantification in Antibody-Chelator Conjugate.

Molecules (Basel, Switzerland)

Avec: Thomas Bouvarel , Nadine Bremeyer , Mimi Gao , Wiebke Holkenjans , Terence Hetzel , Reinhard Pell , Valentina D'Atri , Davy Guillarme

Automated Hydrophobic Interaction Chromatography Screening Combined with

Analytical chemistry

Avec: Rodell C Barrientos , Gioacchino Luca Losacco , Mohammadmehdi Azizi , Heather Wang , Anh Nguyet Nguyen , Vladimir Shchurik , Andrew Singh , Douglas Richardson , Ian Mangion , Davy Guillarme , Erik L Regalado , Imad A Haidar Ahmad

Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody-Drug Conjugates: Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS Analysis.

Analytical chemistry

Avec: Bastiaan L Duivelshof , Evolène Deslignière , Oscar Hernandez-Alba , Anthony Ehkirch , Hanna Toftevall , Jonathan Sjögren , Sarah Cianferani , Alain Beck , Davy Guillarme , Valentina D'Atri

Impact of particle size gradients on the apparent efficiency of chromatographic columns.

Journal of chromatography. A

Avec: Santiago Codesido , Serge Rudaz , Jean-Luc Veuthey , Davy Guillarme , Gert Desmet , Szabolcs Fekete

Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000 Å stationary phase.

Journal of chromatography. A

Avec: David V McCalley , Davy Guillarme

Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction.

Methods in molecular biology (Clifton, N.J.)

Avec: Elsa Wagner-Rousset , Olivier Colas , Yannis-Nicolas François , Sabine Heinisch , Davy Guillarme , Sarah Cianférani , Alain Beck

Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications.

Analytica chimica acta

Avec: Bastiaan L Duivelshof , Wim Jiskoot , Alain Beck , Jean-Luc Veuthey , Davy Guillarme , Valentina D'Atri

Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future.

Expert review of proteomics

Avec: Alain Beck , Valentina D'Atri , Anthony Ehkirch , Szabolcs Fekete , Oscar Hernandez-Alba , Rabah Gahoual , Emmanuel Leize-Wagner , Yannis François , Davy Guillarme , Sarah Cianférani

A scoring approach for multi-platform acquisition in metabolomics.

Journal of chromatography. A

Avec: Julian Pezzatti , Víctor González-Ruiz , Santiago Codesido , Yoric Gagnebin , Abhinav Joshi , Davy Guillarme , Julie Schappler , Didier Picard , Julien Boccard , Serge Rudaz

Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography - Mass spectrometry.

Analytica chimica acta

Avec: Honorine Lardeux , Bastiaan L Duivelshof , Olivier Colas , Alain Beck , David V McCalley , Davy Guillarme , Valentina D'Atri

Algorithms to optimize multi-column chromatographic separations of proteins.

Journal of chromatography. A

Avec: Santiago Codesido , Davy Guillarme , Szabolcs Fekete

Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniques.

Talanta

Avec: Bastiaan L Duivelshof , Alain Beck , Davy Guillarme , Valentina D'Atri

Quantitative

Pharmaceutics

Avec: Bastiaan L Duivelshof , Steffy Denorme , Koen Sandra , Xiaoxiao Liu , Alain Beck , Matthew A Lauber , Davy Guillarme , Valentina D'Atri

Using 1.5 mm internal diameter columns for optimal compatibility with current liquid chromatographic systems.

Journal of chromatography. A

Avec: Szabolcs Fekete , Amarande Murisier , Gioacchino Luca Losacco , Jason Lawhorn , Justin M Godinho , Harry Ritchie , Barry E Boyes , Davy Guillarme

State-of-the-Art Native Mass Spectrometry and Ion Mobility Methods to Monitor Homogeneous Site-Specific Antibody-Drug Conjugates Synthesis.

Pharmaceuticals (Basel, Switzerland)

Avec: Evolène Deslignière , Anthony Ehkirch , Bastiaan L Duivelshof , Hanna Toftevall , Jonathan Sjögren , Davy Guillarme , Valentina D'Atri , Alain Beck , Oscar Hernandez-Alba , Sarah Cianférani

Fast Optimization of Supercritical Fluid Chromatography-Mass Spectrometry Interfacing Using Prediction Equations.

Analytical chemistry

Avec: Kateřina Plachká , Tat'ána Gazárková , Jan Škop , Davy Guillarme , Frantisek Svec , Lucie Nováková

Monitoring multiple quality attributes of a complex Fc-fusion protein during cell culture production processes by mD-LC-MS peptide mapping.

Talanta

Avec: Julien Camperi , Sanket Dahotre , Davy Guillarme , Cinzia Stella

The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides.

Journal of chromatography. A

Avec: Honorine Lardeux , Alexandre Goyon , Kelly Zhang , Jennifer M Nguyen , Matthew A Lauber , Davy Guillarme , Valentina D'Atri

Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticals.

Journal of chromatography. A

Avec: Thomas Bouvarel , Bastiaan L Duivelshof , Julien Camperi , Tilman Schlothauer , Alexander Knaupp , Cinzia Stella , Davy Guillarme

Reversed HILIC Gradient: A Powerful Strategy for On-Line Comprehensive 2D-LC.

Molecules (Basel, Switzerland)

Avec: Soraya Chapel , Florent Rouvière , Davy Guillarme , Sabine Heinisch

Erratum: Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology.

Molecular therapy. Methods & clinical development

Avec: Aurelien Lathuiliere , Remi Vernet , Emily Charrier , Muriel Urwyler , Olivier Von Rohr , Marie-Claude Belkouch , Valentin Saingier , Thomas Bouvarel , Davy Guillarme , Adrien Engel , Patrick Salmon , Thomas Laumonier , Julien Grogg , Nicolas Mach

Boosting the Separation of Adeno-Associated Virus Capsid Proteins by Liquid Chromatography and Capillary Electrophoresis Approaches.

International journal of molecular sciences

Avec: Megane K Aebischer , Thomas Bouvarel , Emmalyn Barrozo , Dominik Kochardt , Carsten Elger , Markus Haindl , Raphael Ruppert , Davy Guillarme , Valentina D'Atri

Challenges in ESI-MS-based Untargeted Metabolomics.

Chimia

Avec: Elena Tobolkina , Víctor González-Ruiz , Isabel Meister , Miguel De Figueiredo , Davy Guillarme , Julien Boccard , Serge Rudaz

Multi-dimensional technology - Recent advances and applications for biotherapeutic characterization.

Journal of separation science

Avec: Thomas Bouvarel , Julien Camperi , Davy Guillarme

Substantial benefits of an inert biphenyl column for the analysis of steroids and their phase II metabolites in biological samples.

Journal of separation science

Avec: Mathieu Galmiche , Marie-Anaïs Monat , Diego A Lopez , Cyrille Lamboley , Paul Connolly , Sergey Girel , Davy Guillarme , Isabel Meister , Serge Rudaz

Unravelling the Link between Oligonucleotide Structure and Diastereomer Separation in Hydrophilic Interaction Chromatography.

Analytical chemistry

Avec: Honorine Lardeux , Kathrin Stavenhagen , Clément Paris , Rikke Dueholm , Camille Kurek , Leonardo De Maria , Felix Gnerlich , Tomas Leek , Werngard Czechtizky , Davy Guillarme , Manasses Jora

Assessment of chemical stability of monoclonal antibody and antibody drug conjugate administered by pressurized intraperitoneal aerosol chemotherapy.

Journal of pharmaceutical and biomedical analysis

Avec: Valentina D'Atri , Guillaume Galy , Mathias Buff , Mateusz Imiołek , Martin Hübner , Manuela Undurraga , Sana Intidhar Labidi-Galy , Davy Guillarme , Laurent Carrez

Characterization of Glycosylated Proteins at Subunit Level by HILIC/MS.

Methods in molecular biology (Clifton, N.J.)

Avec: Valentina D'Atri , Davy Guillarme

Ion mobility-high resolution mass spectrometry in anti-doping analysis. Part I: Implementation of a screening method with the assessment of a library of substances prohibited in sports.

Analytica chimica acta

Avec: Kateřina Plachká , Julian Pezzatti , Alessandro Musenga , Raul Nicoli , Tiia Kuuranne , Serge Rudaz , Lucie Nováková , Davy Guillarme

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept.

Analytical chemistry

Avec: Szabolcs Fekete , Balázs Bobály , Jennifer M Nguyen , Alain Beck , Jean-Luc Veuthey , Kevin Wyndham , Matthew A Lauber , Davy Guillarme

Supercritical fluid chromatography - Mass spectrometry in metabolomics: Past, present, and future perspectives.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Bas van de Velde , Davy Guillarme , Isabelle Kohler

Therapeutic Fc-fusion proteins: Current analytical strategies.

Journal of separation science

Avec: Bastiaan L Duivelshof , Amarande Murisier , Julien Camperi , Szabolcs Fekete , Alain Beck , Davy Guillarme , Valentina D'Atri

Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities.

Journal of pharmaceutical and biomedical analysis

Avec: Elsa Wagner , Olivier Colas , Stéphane Chenu , Alexandre Goyon , Amarande Murisier , Sarah Cianferani , Yannis François , Szabolcs Fekete , Davy Guillarme , Valentina D'Atri , Alain Beck

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products.

Journal of pharmaceutical and biomedical analysis

Avec: Evelin Farsang , Davy Guillarme , Jean-Luc Veuthey , Alain Beck , Matthew Lauber , Andrew Schmudlach , Szabolcs Fekete

Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations.

Journal of chromatography. A

Avec: Amarande Murisier , Matthew Lauber , Stephen J Shiner , Davy Guillarme , Szabolcs Fekete

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases.

Journal of pharmaceutical and biomedical analysis

Avec: Amarande Murisier , Evelin Farsang , Krisztián Horváth , Matthew Lauber , Alain Beck , Davy Guillarme , Szabolcs Fekete

A generic workflow for the characterization of therapeutic monoclonal antibodies-application to daratumumab.

Analytical and bioanalytical chemistry

Avec: Bastiaan L Duivelshof , Szabolcs Fekete , Davy Guillarme , Valentina D'Atri

Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?

Journal of chromatography. A

Avec: Valentina D'Atri , Reinhard Pell , Adrian Clarke , Davy Guillarme , Szabolcs Fekete

Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: F Mueller , G L Losacco , R Nicoli , D Guillarme , A Thomas , E Grata

Interlaboratory study of a supercritical fluid chromatography method for the determination of pharmaceutical impurities: Evaluation of multi-systems reproducibility.

Journal of pharmaceutical and biomedical analysis

Avec: Amandine Dispas , Adrian Clarke , Alexandre Grand-Guillaume Perrenoud , Luca Gioacchino Losacco , Jean-Luc Veuthey , Quentin Gros , Jérémy Molineau , Angéline Noireau , Caroline West , Fabio Salafia , Mariosimone Zoccali , Luigi Mondello , Amber Guillen , Jenny Wang , Kelly Zhang , Philipp Jochems , Gesa Schad , Kosuke Nakajima , Shinnosuke Horie , Jan Joseph , Maria Kristina Parr , Pierre Billemont , Antoni Severino , Sonja Schneider , Edgar Naegele , Daniel Kutscher , Rick Wikfors , Regina Black , Lee Ingvaldson , Jimmy Oliveira Da Silva , Raffeal Bennett , Erik L Regalado , Thi Phuong Thuy Hoang , David Touboul , Yana Nikolova , Mariana Kamenova-Nacheva , Vladimir Dimitrov , Blair K Berger , Kevin A Schug , Solène Kerviel-Guillon , Fabien Mauge , Masatomo Takahashi , Yoshihiro Izumi , Takeshi Bamba , Florent Rouvière , Sabine Heinisch , Davy Guillarme , Philippe Hubert

Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS.

Talanta

Avec: Julien Camperi , Ingrid Grunert , Katrin Heinrich , Martin Winter , Saban Özipek , Sina Hoelterhoff , Thomas Weindl , Kilian Mayr , Patrick Bulau , Monika Meier , Michael Mølhøj , Michael Leiss , Davy Guillarme , Anja Bathke , Cinzia Stella

New wide-pore superficially porous stationary phases with low hydrophobicity applied for the analysis of monoclonal antibodies.

Journal of chromatography. A

Avec: Szabolcs Fekete , Amarande Murisier , Alain Beck , Jason Lawhorn , Harry Ritchie , Barry Boyes , Davy Guillarme

Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products.

Journal of separation science

Avec: Amarande Murisier , Marie Andrie , Szabolcs Fekete , Matthew Lauber , Valentina D'Atri , Katharina Iwan , Davy Guillarme

Sub/supercritical fluid chromatography versus liquid chromatography for peptide analysis.

Journal of chromatography. A

Avec: Riccardo Deidda , Gioacchino Luca Losacco , Cedric Schelling , Erik L Regalado , Jean-Luc Veuthey , Davy Guillarme

Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology.

Molecular therapy. Methods & clinical development

Investigation of several chromatographic approaches for untargeted profiling of central carbon metabolism.

Journal of chromatography. A

Avec: Sergey Girel , Davy Guillarme , Szabolcs Fekete , Serge Rudaz , Víctor González-Ruiz

Ultra-short columns for the chromatographic analysis of large molecules.

Journal of chromatography. A

Avec: Szabolcs Fekete , Davy Guillarme

Practical study on the impact of injection conditions in gradient elution mode for the analysis of therapeutic proteins when using very short columns.

Journal of chromatography. A

Avec: Raquel Pérez-Robles , Szabolcs Fekete , Natalia Navas , Davy Guillarme

Why is there no biosimilar of Erbitux®?

Journal of pharmaceutical and biomedical analysis

Avec: Emmanuel Douez , Valentina D'Atri , Davy Guillarme , Daniel Antier , Mathieu Guerriaud , Alain Beck , Hervé Watier , Laura Foucault-Fruchard

Réseau de co-auteurs

Szabolcs Fekete 37 collaborations

Valentina D'Atri 29 collaborations

Alain Beck 25 collaborations

Amarande Murisier 16 collaborations

Serge Rudaz 14 collaborations

Jean-Luc Veuthey 14 collaborations

Matthew Lauber 11 collaborations

Cinzia Stella 11 collaborations

Gioacchino Luca Losacco 11 collaborations

Bastiaan L Duivelshof 11 collaborations

Julien Camperi 10 collaborations

Erik L Regalado 8 collaborations

Matthew A Lauber 8 collaborations

Alexandre Goyon 7 collaborations

Jennifer M Nguyen 7 collaborations

Honorine Lardeux 7 collaborations

Thomas Bouvarel 7 collaborations

Julian Pezzatti 6 collaborations

Víctor González-Ruiz 6 collaborations

Sabine Heinisch 6 collaborations

Julien Boccard 5 collaborations

Olivier Colas 5 collaborations

Raul Nicoli 5 collaborations

Tiia Kuuranne 5 collaborations

Lucie Nováková 5 collaborations

Imad A Haidar Ahmad 4 collaborations

Ian Mangion 4 collaborations

Evelin Farsang 4 collaborations

Krisztián Horváth 4 collaborations

Lu Dai 4 collaborations

Sarah Cianferani 4 collaborations

Kateřina Plachká 4 collaborations

Heather Wang 4 collaborations

Florent Rouvière 4 collaborations

Kelly Zhang 4 collaborations

Santiago Codesido 4 collaborations

Jonathan Sjögren 3 collaborations

Alessandro Musenga 3 collaborations

Megane K Aebischer 3 collaborations

Jason Lawhorn 3 collaborations

Oscar Hernandez-Alba 3 collaborations

Anthony Ehkirch 3 collaborations

Sarah Cianférani 3 collaborations

Emerson Ferreira Queiroz 2 collaborations

Laurence Marcourt 2 collaborations

Jean-Luc Wolfender 2 collaborations

Raffeal Bennett 2 collaborations

Alexey A Makarov 2 collaborations

Michael Leiss 2 collaborations

Michael Mølhøj 2 collaborations

Xiaoxiao Liu 2 collaborations

Elsa Wagner-Rousset 2 collaborations

Stéphane Chenu 2 collaborations

Yannis-Nicolas François 2 collaborations

Arnaud Delobel 2 collaborations

Kevin Wyndham 2 collaborations

Vladimir Shchurik 2 collaborations

Fabrice Monteau 2 collaborations

Bruno Le Bizec 2 collaborations

Sandrine Fleury-Souverain 2 collaborations

Elsa Wagner 2 collaborations

Soraya Chapel 2 collaborations

Mateusz Imiołek 2 collaborations

Rodell C Barrientos 2 collaborations

Andrew Schmudlach 2 collaborations

Dominik Kochardt 2 collaborations

Carsten Elger 2 collaborations

Markus Haindl 2 collaborations

Raphael Ruppert 2 collaborations

D Guillarme 2 collaborations

Reinhard Pell 2 collaborations

Evolène Deslignière 2 collaborations

Hanna Toftevall 2 collaborations

David V McCalley 2 collaborations

Yannis François 2 collaborations

Harry Ritchie 2 collaborations

Aurelien Lathuiliere 2 collaborations

Remi Vernet 2 collaborations

Emily Charrier 2 collaborations

Muriel Urwyler 2 collaborations

Olivier Von Rohr 2 collaborations

Marie-Claude Belkouch 2 collaborations

Valentin Saingier 2 collaborations

Adrien Engel 2 collaborations

Patrick Salmon 2 collaborations

Thomas Laumonier 2 collaborations

Julien Grogg 2 collaborations

Nicolas Mach 2 collaborations

Isabel Meister 2 collaborations

Sergey Girel 2 collaborations

Adrian Clarke 2 collaborations

Abdulelah Alfattani 1 collaboration

Adlin Afzan 1 collaboration

Guy R Humphrey 1 collaboration

Qi Wang 1 collaboration

Tao Chen 1 collaboration

Bingchuan Wei 1 collaboration

Feng Yang 1 collaboration

Nisana Andersen 1 collaboration

Robert Kopf 1 collaboration

Omar Ismail 1 collaboration

Maureen DeLoffi 1 collaboration

Yury O Tsybin 1 collaboration

Michael J Bolton 1 collaboration

Jonathan Belanger 1 collaboration

Daniel McDonald 1 collaboration

Léonie Pellissier 1 collaboration

Alexey Koval 1 collaboration

Nicole Lecoultre 1 collaboration

Sara Leoni 1 collaboration

Luis-Manuel Quiros-Guerrero 1 collaboration

Morgane Barthélémy 1 collaboration

Sébastien Tardy 1 collaboration

Véronique Eparvier 1 collaboration

Karl Perron 1 collaboration

Jérôme Chave 1 collaboration

Didier Stien 1 collaboration

Katia Gindro 1 collaboration

Vladimir Katanaev 1 collaboration

Xiao Wang 1 collaboration

Ryan D Cohen 1 collaboration

Alastair N Herron 1 collaboration

Sheenagh Aiken 1 collaboration

Daniele Fiorito 1 collaboration

Mikhail Reibarkh 1 collaboration

Timothy Nowak 1 collaboration

Dwight R Stoll 1 collaboration

Varinder K Aggarwal 1 collaboration

Jin-Quan Yu 1 collaboration

Marco Rentsch 1 collaboration

Emmanuelle Bichon 1 collaboration

Tobias Langer 1 collaboration

Carine Schweizer-Grundisch 1 collaboration

Silke Grabherr 1 collaboration

Elsa Bodier-Montagutelli 1 collaboration

Renaud Respaud 1 collaboration

Ming Lei 1 collaboration

Sabrina Ferré 1 collaboration

Nicolas Guichard 1 collaboration

Pascal Bonnabry 1 collaboration

Maykel Hernández-Mesa 1 collaboration

Gitte Barknowitz 1 collaboration

Mathieu Fanuel 1 collaboration

Nicola Dreolin 1 collaboration

David Ropartz 1 collaboration

Evelyne Vigneau 1 collaboration

Sara Stead 1 collaboration

Hélène Rogniaux 1 collaboration

Gaud Dervilly 1 collaboration

Jimmy Oliviera DaSilva 1 collaboration

Jinchu Liu 1 collaboration

Jose Antonio Navarro-Huerta 1 collaboration

Michael B Hicks 1 collaboration

Jimmy O DaSilva 1 collaboration

Miraslava Potapenko 1 collaboration

Fuh-Rong Tsay 1 collaboration

Bastiaan Duivelshof 1 collaboration

Arnold Zöldhegyi 1 collaboration

Claire I Butré 1 collaboration

Hélène Diemer 1 collaboration

Mohamed Hemida 1 collaboration

Andrew N Singh 1 collaboration

Eli Larson 1 collaboration

Wei Xu 1 collaboration

Emmanuel Appiah-Amponsah 1 collaboration

Elisa Marconetto 1 collaboration

Róbert Kormány 1 collaboration

Michael Kim 1 collaboration

Christopher Cornell 1 collaboration

Fred Jacobson 1 collaboration

Dwight Stoll 1 collaboration

Harald Ritchie 1 collaboration

Julien Bourquin 1 collaboration

Hugo Gizardin-Fredon 1 collaboration

Sebastian Pirner 1 collaboration

Vincent Larraillet 1 collaboration

S Fleury-Souverain 1 collaboration

J Maurin 1 collaboration

S Rudaz 1 collaboration

P Bonnabry 1 collaboration

Nadine Bremeyer 1 collaboration

Mimi Gao 1 collaboration

Wiebke Holkenjans 1 collaboration

Terence Hetzel 1 collaboration

Mohammadmehdi Azizi 1 collaboration

Anh Nguyet Nguyen 1 collaboration

Andrew Singh 1 collaboration

Douglas Richardson 1 collaboration

Gert Desmet 1 collaboration

Wim Jiskoot 1 collaboration

Rabah Gahoual 1 collaboration

Emmanuel Leize-Wagner 1 collaboration

Yoric Gagnebin 1 collaboration

Abhinav Joshi 1 collaboration

Julie Schappler 1 collaboration

Didier Picard 1 collaboration

Steffy Denorme 1 collaboration

Koen Sandra 1 collaboration

Justin M Godinho 1 collaboration

Barry E Boyes 1 collaboration

Tat'ána Gazárková 1 collaboration

Jan Škop 1 collaboration

Frantisek Svec 1 collaboration

Sanket Dahotre 1 collaboration

Tilman Schlothauer 1 collaboration

Alexander Knaupp 1 collaboration

Emmalyn Barrozo 1 collaboration

Elena Tobolkina 1 collaboration

Miguel De Figueiredo 1 collaboration

Mathieu Galmiche 1 collaboration

Marie-Anaïs Monat 1 collaboration

Diego A Lopez 1 collaboration

Cyrille Lamboley 1 collaboration

Paul Connolly 1 collaboration

Kathrin Stavenhagen 1 collaboration

Clément Paris 1 collaboration

Rikke Dueholm 1 collaboration

Camille Kurek 1 collaboration

Leonardo De Maria 1 collaboration

Felix Gnerlich 1 collaboration

Tomas Leek 1 collaboration

Werngard Czechtizky 1 collaboration

Manasses Jora 1 collaboration

Guillaume Galy 1 collaboration

Mathias Buff 1 collaboration

Martin Hübner 1 collaboration

Manuela Undurraga 1 collaboration

Sana Intidhar Labidi-Galy 1 collaboration

Laurent Carrez 1 collaboration

Balázs Bobály 1 collaboration

Bas van de Velde 1 collaboration

Isabelle Kohler 1 collaboration

Stephen J Shiner 1 collaboration

F Mueller 1 collaboration

G L Losacco 1 collaboration

R Nicoli 1 collaboration

A Thomas 1 collaboration

E Grata 1 collaboration

Amandine Dispas 1 collaboration

Alexandre Grand-Guillaume Perrenoud 1 collaboration

Luca Gioacchino Losacco 1 collaboration

Quentin Gros 1 collaboration

Jérémy Molineau 1 collaboration

Angéline Noireau 1 collaboration

Caroline West 1 collaboration

Fabio Salafia 1 collaboration

Mariosimone Zoccali 1 collaboration

Luigi Mondello 1 collaboration

Amber Guillen 1 collaboration

Jenny Wang 1 collaboration

Philipp Jochems 1 collaboration

Gesa Schad 1 collaboration

Kosuke Nakajima 1 collaboration

Shinnosuke Horie 1 collaboration

Jan Joseph 1 collaboration

Maria Kristina Parr 1 collaboration

Pierre Billemont 1 collaboration

Antoni Severino 1 collaboration

Sonja Schneider 1 collaboration

Edgar Naegele 1 collaboration

Daniel Kutscher 1 collaboration

Rick Wikfors 1 collaboration

Regina Black 1 collaboration

Lee Ingvaldson 1 collaboration

Jimmy Oliveira Da Silva 1 collaboration

Thi Phuong Thuy Hoang 1 collaboration

David Touboul 1 collaboration

Yana Nikolova 1 collaboration

Mariana Kamenova-Nacheva 1 collaboration

Vladimir Dimitrov 1 collaboration

Blair K Berger 1 collaboration

Kevin A Schug 1 collaboration

Solène Kerviel-Guillon 1 collaboration

Fabien Mauge 1 collaboration

Masatomo Takahashi 1 collaboration

Yoshihiro Izumi 1 collaboration

Takeshi Bamba 1 collaboration

Philippe Hubert 1 collaboration

Ingrid Grunert 1 collaboration

Katrin Heinrich 1 collaboration

Martin Winter 1 collaboration

Saban Özipek 1 collaboration

Sina Hoelterhoff 1 collaboration

Thomas Weindl 1 collaboration

Kilian Mayr 1 collaboration

Patrick Bulau 1 collaboration

Monika Meier 1 collaboration

Anja Bathke 1 collaboration

Barry Boyes 1 collaboration

Marie Andrie 1 collaboration

Katharina Iwan 1 collaboration

Riccardo Deidda 1 collaboration

Cedric Schelling 1 collaboration

Raquel Pérez-Robles 1 collaboration

Natalia Navas 1 collaboration

Emmanuel Douez 1 collaboration

Daniel Antier 1 collaboration

Mathieu Guerriaud 1 collaboration

Hervé Watier 1 collaboration

Laura Foucault-Fruchard 1 collaboration