Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions.
Anti-doping analyses
Identification criteria
Retention time variability
Tandem mass spectrometry
Ultra-high performance supercritical fluid chromatography
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
12 Apr 2020
12 Apr 2020
Historique:
received:
04
11
2019
revised:
06
12
2019
accepted:
09
12
2019
pubmed:
22
12
2019
medline:
15
5
2020
entrez:
22
12
2019
Statut:
ppublish
Résumé
The aim of this study was to estimate the retention time variability under reproducible conditions of an SFC-MS analytical method for routine anti-doping analyses. For this purpose, a set of 51 doping agents, as neat standards and spiked in diluted urine, was used to assess their retention times variability over a period of four months, as well as the column inter-batch reproducibility. Three UHPSFC stationary phases have been employed, the Acquity UPC
Identifiants
pubmed: 31862111
pii: S0021-9673(19)31228-2
doi: 10.1016/j.chroma.2019.460780
pii:
doi:
Substances chimiques
Performance-Enhancing Substances
0
Water
059QF0KO0R
Silicon Dioxide
7631-86-9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
460780Informations de copyright
Copyright © 2019. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.