Patrick Musicha

Affiliations

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Publications (17)

ChloS-HRM, a novel assay to identify chloramphenicol-susceptible Escherichia coli and Klebsiella pneumoniae in Malawi.

The Journal of antimicrobial chemotherapy

Avec: Christopher T Williams , Patrick Musicha , Nicholas A Feasey , Emily R Adams , Thomas Edwards

Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages.

The Journal of antimicrobial chemotherapy

Avec: Patrick Musicha , Chisomo L Msefula , Alison E Mather , Chrispin Chaguza , Amy K Cain , Chikondi Peno , Teemu Kallonen , Margaret Khonga , Brigitte Denis , Katherine J Gray , Robert S Heyderman , Nicholas R Thomson , Dean B Everett , Nicholas A Feasey

Effect of resistance to third-generation cephalosporins on morbidity and mortality from bloodstream infections in Blantyre, Malawi: a prospective cohort study.

The Lancet. Microbe

Avec: Rebecca Lester , Patrick Musicha , Kondwani Kawaza , Josephine Langton , James Mango , Helen Mangochi , Winnie Bakali , Oliver Pearse , Jane Mallewa , Brigitte Denis , Sithembile Bilima , Stephen B Gordon , David G Lalloo , Christopher P Jewell , Nicholas A Feasey

Genomic insights into the 2022-2023Vibrio cholerae outbreak in Malawi.

Nature communications

Avec: Chrispin Chaguza , Innocent Chibwe , David Chaima , Patrick Musicha , Latif Ndeketa , Watipaso Kasambara , Chimwemwe Mhango , Upendo L Mseka , Joseph Bitilinyu-Bangoh , Bernard Mvula , Wakisa Kipandula , Patrick Bonongwe , Richard J Munthali , Selemani Ngwira , Chikondi A Mwendera , Akuzike Kalizang'oma , Kondwani C Jambo , Dzinkambani Kambalame , Arox W Kamng'ona , A Duncan Steele , Annie Chauma-Mwale , Daniel Hungerford , Matthew Kagoli , Martin M Nyaga , Queen Dube , Neil French , Chisomo L Msefula , Nigel A Cunliffe , Khuzwayo C Jere

Duration of Carbapenemase-Producing Enterobacteriaceae Carriage in Hospital Patients.

Emerging infectious diseases

Avec: Yin Mo , Anastasia Hernandez-Koutoucheva , Patrick Musicha , Denis Bertrand , David Lye , Oon Tek Ng , Shannon N Fenlon , Swaine L Chen , Moi Lin Ling , Wen Ying Tang , Timothy Barkham , Niranjan Nagarajan , Ben S Cooper , Kalisvar Marimuthu

Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Chrispin Chaguza , Ellen Heinsbroek , Rebecca A Gladstone , Terence Tafatatha , Maaike Alaerts , Chikondi Peno , Jennifer E Cornick , Patrick Musicha , Naor Bar-Zeev , Arox Kamng'ona , Aras Kadioglu , Lesley McGee , William P Hanage , Robert F Breiman , Robert S Heyderman , Neil French , Dean B Everett , Stephen D Bentley

Emerging Resistance to Empiric Antimicrobial Regimens for Pediatric Bloodstream Infections in Malawi (1998-2017).

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Pui-Ying Iroh Tam , Patrick Musicha , Kondwani Kawaza , Jenifer Cornick , Brigitte Denis , Bridget Freyne , Dean Everett , Queen Dube , Neil French , Nicholas Feasey , Robert Heyderman

Evidence of widespread endemic populations of highly multidrug resistant Klebsiella pneumoniae in hospital settings in Hanoi, Vietnam: a prospective cohort study.

The Lancet. Microbe

Avec: My H Pham , Le Thi Hoi , Mathew A Beale , Fahad A Khokhar , Nguyen Thi Hoa , Patrick Musicha , Grace A Blackwell , Hoang Bao Long , Dang Thi Huong , Nguyen Gia Binh , Dao Xuan Co , Tran Giang , Cuong Bui , Hai Ninh Tran , James Bryan , Archie Herrick , Theresa Feltwell , Behzad Nadjm , Julian Parkhill , Hindrik Rogier van Doorn , Nguyen Vu Trung , Nguyen Van Kinh , Mili Estée Török , Nicholas R Thomson

A novel air-dried multiplex high-resolution melt assay for the detection of extended-spectrum β-lactamase and carbapenemase genes.

Journal of global antimicrobial resistance

Avec: Ana I Cubas-Atienzar , Christopher T Williams , Abhilasha Karkey , Sabina Dongol , Manandhar Sulochana , Shrestha Rajendra , Glyn Hobbs , Katie Evans , Patrick Musicha , Nicholas Feasey , Luis E Cuevas , Emily R Adams , Thomas Edwards

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales.

Nature communications

Avec: Fabrice E Graf , Richard N Goodman , Sarah Gallichan , Sally Forrest , Esther Picton-Barlow , Alice J Fraser , Minh-Duy Phan , Madalitso Mphasa , Alasdair T M Hubbard , Patrick Musicha , Mark A Schembri , Adam P Roberts , Thomas Edwards , Joseph M Lewis , Nicholas A Feasey

Prevalence and outcome of bloodstream infections due to third-generation cephalosporin-resistant Enterobacteriaceae in sub-Saharan Africa: a systematic review.

The Journal of antimicrobial chemotherapy

Avec: Rebecca Lester , Patrick Musicha , Nadja van Ginneken , Angela Dramowski , Davidson H Hamer , Paul Garner , Nicholas A Feasey

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients.

Nature microbiology

Avec: Ricardo León-Sampedro , Javier DelaFuente , Cristina Díaz-Agero , Thomas Crellen , Patrick Musicha , Jerónimo Rodríguez-Beltrán , Carmen de la Vega , Marta Hernández-García , Auteur inconnu , Nieves López-Fresneña , Patricia Ruiz-Garbajosa , Rafael Cantón , Ben S Cooper , Álvaro San Millán

Prevalence, risk factors, and antimicrobial resistance of endemic healthcare-associated infections in Africa: a systematic review and meta-analysis.

BMC infectious diseases

Avec: Gabriel Kambale Bunduki , Effita Masoamphambe , Tilly Fox , Janelisa Musaya , Patrick Musicha , Nicholas Feasey

Parallel evolution leading to impaired biofilm formation in invasive Salmonella strains.

PLoS genetics

Avec: Keith D MacKenzie , Yejun Wang , Patrick Musicha , Elizabeth G Hansen , Melissa B Palmer , Dakoda J Herman , Nicholas A Feasey , Aaron P White

Genomic investigation of a suspected

Microbial genomics

Avec: Jennifer Cornick , Patrick Musicha , Chikondi Peno , Ezgi Seager , Pui-Ying Iroh Tam , Sithembile Bilima , Aisleen Bennett , Neil Kennedy , Nicholas Feasey , Eva Heinz , Amy K Cain

Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.

Genome medicine

Avec: Eva Heinz , Oliver Pearse , Allan Zuza , Sithembile Bilima , Chisomo Msefula , Patrick Musicha , Patriciah Siyabu , Edith Tewesa , Fabrice E Graf , Rebecca Lester , Samantha Lissauer , Jennifer Cornick , Joseph M Lewis , Kondwani Kawaza , Nicholas R Thomson , Nicholas A Feasey

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs).

Wellcome open research

Avec: Derek Cocker , Melodie Sammarro , Kondwani Chidziwisano , Nicola Elviss , Shevin T Jacob , Henry Kajumbula , Lawrence Mugisha , David Musoke , Patrick Musicha , Adam P Roberts , Barry Rowlingson , Andrew C Singer , Rachel L Byrne , Thomas Edwards , Rebecca Lester , Catherine N Wilson , Beth Hollihead , Nicholas R Thomson , Christopher P Jewell , Tracy Morse , Nicholas A Feasey

Réseau de co-auteurs

Nicholas A Feasey 8 collaborations

Thomas Edwards 4 collaborations

Nicholas R Thomson 4 collaborations

Rebecca Lester 4 collaborations

Nicholas Feasey 4 collaborations

Chrispin Chaguza 3 collaborations

Chikondi Peno 3 collaborations

Brigitte Denis 3 collaborations

Kondwani Kawaza 3 collaborations

Sithembile Bilima 3 collaborations

Neil French 3 collaborations

Christopher T Williams 2 collaborations

Emily R Adams 2 collaborations

Chisomo L Msefula 2 collaborations

Amy K Cain 2 collaborations

Robert S Heyderman 2 collaborations

Dean B Everett 2 collaborations

Oliver Pearse 2 collaborations

Christopher P Jewell 2 collaborations

Queen Dube 2 collaborations

Ben S Cooper 2 collaborations

Pui-Ying Iroh Tam 2 collaborations

Fabrice E Graf 2 collaborations

Adam P Roberts 2 collaborations

Joseph M Lewis 2 collaborations

Jennifer Cornick 2 collaborations

Eva Heinz 2 collaborations

Alison E Mather 1 collaboration

Teemu Kallonen 1 collaboration

Margaret Khonga 1 collaboration

Katherine J Gray 1 collaboration

Josephine Langton 1 collaboration

James Mango 1 collaboration

Helen Mangochi 1 collaboration

Winnie Bakali 1 collaboration

Jane Mallewa 1 collaboration

Stephen B Gordon 1 collaboration

David G Lalloo 1 collaboration

Innocent Chibwe 1 collaboration

David Chaima 1 collaboration

Latif Ndeketa 1 collaboration

Watipaso Kasambara 1 collaboration

Chimwemwe Mhango 1 collaboration

Upendo L Mseka 1 collaboration

Joseph Bitilinyu-Bangoh 1 collaboration

Bernard Mvula 1 collaboration

Wakisa Kipandula 1 collaboration

Patrick Bonongwe 1 collaboration

Richard J Munthali 1 collaboration

Selemani Ngwira 1 collaboration

Chikondi A Mwendera 1 collaboration

Akuzike Kalizang'oma 1 collaboration

Kondwani C Jambo 1 collaboration

Dzinkambani Kambalame 1 collaboration

Arox W Kamng'ona 1 collaboration

A Duncan Steele 1 collaboration

Annie Chauma-Mwale 1 collaboration

Daniel Hungerford 1 collaboration

Matthew Kagoli 1 collaboration

Martin M Nyaga 1 collaboration

Nigel A Cunliffe 1 collaboration

Khuzwayo C Jere 1 collaboration

Yin Mo 1 collaboration

Anastasia Hernandez-Koutoucheva 1 collaboration

Denis Bertrand 1 collaboration

David Lye 1 collaboration

Oon Tek Ng 1 collaboration

Shannon N Fenlon 1 collaboration

Swaine L Chen 1 collaboration

Moi Lin Ling 1 collaboration

Wen Ying Tang 1 collaboration

Timothy Barkham 1 collaboration

Niranjan Nagarajan 1 collaboration

Kalisvar Marimuthu 1 collaboration

Ellen Heinsbroek 1 collaboration

Rebecca A Gladstone 1 collaboration

Terence Tafatatha 1 collaboration

Maaike Alaerts 1 collaboration

Jennifer E Cornick 1 collaboration

Naor Bar-Zeev 1 collaboration

Arox Kamng'ona 1 collaboration

Aras Kadioglu 1 collaboration

Lesley McGee 1 collaboration

William P Hanage 1 collaboration

Robert F Breiman 1 collaboration

Stephen D Bentley 1 collaboration

Jenifer Cornick 1 collaboration

Bridget Freyne 1 collaboration

Dean Everett 1 collaboration

Robert Heyderman 1 collaboration

My H Pham 1 collaboration

Le Thi Hoi 1 collaboration

Mathew A Beale 1 collaboration

Fahad A Khokhar 1 collaboration

Nguyen Thi Hoa 1 collaboration

Grace A Blackwell 1 collaboration

Hoang Bao Long 1 collaboration

Dang Thi Huong 1 collaboration

Nguyen Gia Binh 1 collaboration

Dao Xuan Co 1 collaboration

Tran Giang 1 collaboration

Cuong Bui 1 collaboration

Hai Ninh Tran 1 collaboration

James Bryan 1 collaboration

Archie Herrick 1 collaboration

Theresa Feltwell 1 collaboration

Behzad Nadjm 1 collaboration

Julian Parkhill 1 collaboration

Hindrik Rogier van Doorn 1 collaboration

Nguyen Vu Trung 1 collaboration

Nguyen Van Kinh 1 collaboration

Mili Estée Török 1 collaboration

Ana I Cubas-Atienzar 1 collaboration

Abhilasha Karkey 1 collaboration

Sabina Dongol 1 collaboration

Manandhar Sulochana 1 collaboration

Shrestha Rajendra 1 collaboration

Glyn Hobbs 1 collaboration

Katie Evans 1 collaboration

Luis E Cuevas 1 collaboration

Richard N Goodman 1 collaboration

Sarah Gallichan 1 collaboration

Sally Forrest 1 collaboration

Esther Picton-Barlow 1 collaboration

Alice J Fraser 1 collaboration

Minh-Duy Phan 1 collaboration

Madalitso Mphasa 1 collaboration

Alasdair T M Hubbard 1 collaboration

Mark A Schembri 1 collaboration

Nadja van Ginneken 1 collaboration

Angela Dramowski 1 collaboration

Davidson H Hamer 1 collaboration

Paul Garner 1 collaboration

Ricardo León-Sampedro 1 collaboration

Javier DelaFuente 1 collaboration

Cristina Díaz-Agero 1 collaboration

Thomas Crellen 1 collaboration

Jerónimo Rodríguez-Beltrán 1 collaboration

Carmen de la Vega 1 collaboration

Marta Hernández-García 1 collaboration

None None 1 collaboration

Nieves López-Fresneña 1 collaboration

Patricia Ruiz-Garbajosa 1 collaboration

Rafael Cantón 1 collaboration

Álvaro San Millán 1 collaboration

Gabriel Kambale Bunduki 1 collaboration

Effita Masoamphambe 1 collaboration

Tilly Fox 1 collaboration

Janelisa Musaya 1 collaboration

Keith D MacKenzie 1 collaboration

Yejun Wang 1 collaboration

Elizabeth G Hansen 1 collaboration

Melissa B Palmer 1 collaboration

Dakoda J Herman 1 collaboration

Aaron P White 1 collaboration

Ezgi Seager 1 collaboration

Aisleen Bennett 1 collaboration

Neil Kennedy 1 collaboration

Allan Zuza 1 collaboration

Chisomo Msefula 1 collaboration

Patriciah Siyabu 1 collaboration

Edith Tewesa 1 collaboration

Samantha Lissauer 1 collaboration

Derek Cocker 1 collaboration

Melodie Sammarro 1 collaboration

Kondwani Chidziwisano 1 collaboration

Nicola Elviss 1 collaboration

Shevin T Jacob 1 collaboration

Henry Kajumbula 1 collaboration

Lawrence Mugisha 1 collaboration

David Musoke 1 collaboration

Barry Rowlingson 1 collaboration

Andrew C Singer 1 collaboration

Rachel L Byrne 1 collaboration

Catherine N Wilson 1 collaboration

Beth Hollihead 1 collaboration

Tracy Morse 1 collaboration