Pierre Chelle

Affiliations

School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.

Publications (27)

Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Jacky K Yu , Alfonso Iorio , Pierre Chelle , Andrea N Edginton

Pediatric Dose Selection for Therapeutic Proteins.

Journal of clinical pharmacology

Avec: Paul R V Malik , Zaid H Temrikar , Pierre Chelle , Andrea N Edginton , Bernd Meibohm

Development of a Plasminogen Population PK model supporting prophylactic replacement therapy for Plasminogen deficient patients within the WAPPS-Hemo platform.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Pierre Chelle , Dagmar Hajducek , Karen Thibaudeau , Nicholas Hobson , Alfonso Iorio , Amy Shapiro , Andrea Edginton

Development and evaluation of the population pharmacokinetic models for FVIII and FIX concentrates of the WAPPS-Hemo project.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Dagmar M Hajducek , Pierre Chelle , Cedric Hermans , Alfonso Iorio , Alanna McEneny-King , Jacky Yu , Andrea Edginton

Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?

Journal of thrombosis and haemostasis : JTH

Avec: Manuel D Carcao , Pierre Chelle , Emily Clarke , Lussia Kim , Laura Tiseo , Massimo Morfini , Taneya Hossain , Margaret L Rand , Christine Brown , Andrea N Edginton , David Lillicrap , Alfonso Iorio , Victor S Blanchette

Use of population PK/PD approach to model the thrombin generation assay: assessment in haemophilia A plasma samples spiked by a TFPI antibody.

Journal of pharmacokinetics and pharmacodynamics

Avec: Raphaël Crépin , Claire Morin , Aurélie Montmartin , Brigitte Tardy-Poncet , Pierre Chelle

Revised terminal half-life of nonacog alfa as derived from extended sampling data: A real-world study involving 64 haemophilia B patients on nonacog alfa regular prophylaxis.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Brigitte Tardy , Thierry Lambert , Pierre Chamouni , Aurélie Montmartin , Marc Trossaert , Ségolène Claeyssens , Claire Berger , Laurent Ardillon , Valérie Gay , Xavier Delavenne , Annie Harroche , Pierre Chelle

Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients.

Journal of pharmacokinetics and pharmacodynamics

Avec: Pierre Chelle , Cindy H T Yeung , Santiago Bonanad , Juan Cristóbal Morales Muñoz , Margareth C Ozelo , Juan Eduardo Megías Vericat , Alfonso Iorio , Jeffrey Spears , Roser Mir , Andrea Edginton

Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation.

Pharmaceutics

Avec: Mohamed Aborig , Paul R V Malik , Shruti Nambiar , Pierre Chelle , Johnson Darko , Anthony Mutsaers , Andrea N Edginton , Andre Fleck , Ernest Osei , Shawn Wettig

Tissue factor pathway inhibitor is the main determinant of thrombin generation in haemophilic patients.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Pierre Chelle , Aurélie Montmartin , Pauline Damien , Michèle Piot , Michel Cournil , Anne Lienhart , Fabienne Genre-Volot , Hervé Chambost , Claire Morin , Brigitte Tardy-Poncet

Integrated Electrochemical Aptamer Biosensing and Colorimetric pH Monitoring via Hydrogel Microneedle Assays for Assessing Antibiotic Treatment.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Fatemeh Keyvani , Peyman GhavamiNejad , Mahmoud Ayman Saleh , Mohammad Soltani , Yusheng Zhao , Sadegh Sadeghzadeh , Arash Shakeri , Pierre Chelle , Hanjia Zheng , Fasih A Rahman , Sarah Mahshid , Joe Quadrilatero , Praveen P N Rao , Andrea Edginton , Mahla Poudineh

Clustering of Thrombin Generation Test Data Using a Reduced Mathematical Model of Blood Coagulation.

Acta biotheoretica

Avec: N Ratto , A Tokarev , P Chelle , B Tardy-Poncet , V Volpert

Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization.

Journal of pharmacokinetics and pharmacodynamics

Avec: Alanna McEneny-King , Pierre Chelle , Gary Foster , Arun Keepanasseril , Alfonso Iorio , Andrea N Edginton

Patient-Specific Modelling of Blood Coagulation.

Bulletin of mathematical biology

Avec: N Ratto , A Bouchnita , P Chelle , M Marion , M Panteleev , D Nechipurenko , B Tardy-Poncet , V Volpert

Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database.

Journal of thrombosis and haemostasis : JTH

Avec: Olav Versloot , Emma Iserman , Pierre Chelle , Federico Germini , Andrea N Edginton , Roger E G Schutgens , Alfonso Iorio , Kathelijn Fischer , Auteur inconnu

Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Jan Astermark , Anna Olsson , Pierre Chelle , Kinga Täckström , Maria Walger , Maria Magnusson , Alfonso Iorio

External qualification of the Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) models for octocog alfa using real patient data.

Research and practice in thrombosis and haemostasis

Avec: Pierre Chelle , Dagmar Hajducek , Mohammed Mahdi , Stuart Young , Alfonso Iorio , Josh Silvertown , Andrea Edginton

Limited sampling strategies for accurate determination of extended half-life factor VIII pharmacokinetics in severe haemophilia A patients.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Alanna McEneny-King , Pierre Chelle , Margaret H Goggans , Patricia J Barker , Timothy W Jacobs , Ellis J Neufeld , Ulrike M Reiss , John C Panetta

Correction to: Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients.

Journal of pharmacokinetics and pharmacodynamics

A comparison of methods for prediction of pharmacokinetics across factor concentrate switching in hemophilia patients.

Thrombosis research

Avec: Jacky K Yu , Alfonso Iorio , Pierre Chelle , Andrea N Edginton

Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate

Clinical pharmacokinetics

Avec: Pierre Chelle , Cindy H T Yeung , Stacy E Croteau , Jennifer Lissick , Vinod Balasa , Christina Ashburner , Young Shil Park , Santiago Bonanad , Juan Eduardo Megías-Vericat , Azusa Nagao , Tung Wynn , Fernando Corrales-Medina , Huyen Tran , Anjali Sharathkumar , Meera Chitlur , Samuel Sarmiento , Andrea Edginton , Alfonso Iorio

Multicentre pharmacokinetic evaluation of rFVIII-Fc (efmoroctocog alfa) in a real life and comparison with non-extended half-life FVIII concentrates.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Claire Pouplard , Laurent Sattler , Anne Ryman , Valérie Eschwege , Emmanuel De Maistre , Claire Flaujac , Jean Szymezak , François Grand , Yohann Repesse , Hubert Galinat , Magali Donnard , Catherine Ternisien , Alfonso Iorio , Pierre Chelle , Emmanuelle Jeanpierre , Auteur inconnu

A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates.

Journal of thrombosis and haemostasis : JTH

Avec: Pierre Chelle , Alfonso Iorio , Andrea N Edginton

Predicting Individual Changes in Terminal Half-Life After Switching to Extended Half-Life Concentrates in Patients With Severe Hemophilia.

HemaSphere

Avec: Olav Versloot , Emma Iserman , Pierre Chelle , Federico Germini , Andrea N Edginton , Roger E G Schutgens , Alfonso Iorio , Kathelijn Fischer

Estimated prophylactic dose required to achieve 3% trough as a function of age and concentrate class in multi-country severe WAPPS-Hemo haemophilia patients.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Dagmar M Hajducek , Pierre Chelle , Alfonso Iorio , Emma Iserman , Andrea N Edginton

Infliximab in paediatric inflammatory bowel disease: External evaluation of population pharmacokinetic models.

British journal of clinical pharmacology

Avec: Omnia Salah Heikal , Patrick F van Rheenen , Daan J Touw , Jos G W Kosterink , Marina Maurer , Jeroen V Koomen , Pierre Chelle , Paola Mian

Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), octocog alfa, to extended half-life rFVIII, damoctocog alfa pegol, in persons with haemophilia A ≥ 12 years followed in a Comprehensive Hemophilia Care Program in Canada.

Haemophilia : the official journal of the World Federation of Hemophilia

Avec: Davide Matino , Federico Germini , Anthony K C Chan , Kay Decker , Emma Iserman , Pierre Chelle , Andrea N Edginton , Olayide Oladoyinbo , Elisabetta Trinari , Arun Keepanasseril , Alfonso Iorio

Réseau de co-auteurs

Alfonso Iorio 17 collaborations

Andrea N Edginton 11 collaborations

Andrea Edginton 7 collaborations

Emma Iserman 4 collaborations

Alanna McEneny-King 3 collaborations

Aurélie Montmartin 3 collaborations

Cindy H T Yeung 3 collaborations

Santiago Bonanad 3 collaborations

Federico Germini 3 collaborations

Jacky K Yu 2 collaborations

Paul R V Malik 2 collaborations

Dagmar Hajducek 2 collaborations

Dagmar M Hajducek 2 collaborations

Claire Morin 2 collaborations

Brigitte Tardy-Poncet 2 collaborations

Juan Cristóbal Morales Muñoz 2 collaborations

Margareth C Ozelo 2 collaborations

Juan Eduardo Megías Vericat 2 collaborations

Jeffrey Spears 2 collaborations

Roser Mir 2 collaborations

N Ratto 2 collaborations

P Chelle 2 collaborations

B Tardy-Poncet 2 collaborations

V Volpert 2 collaborations

Arun Keepanasseril 2 collaborations

Olav Versloot 2 collaborations

Roger E G Schutgens 2 collaborations

Kathelijn Fischer 2 collaborations

None None 2 collaborations

Zaid H Temrikar 1 collaboration

Bernd Meibohm 1 collaboration

Karen Thibaudeau 1 collaboration

Nicholas Hobson 1 collaboration

Amy Shapiro 1 collaboration

Cedric Hermans 1 collaboration

Jacky Yu 1 collaboration

Manuel D Carcao 1 collaboration

Emily Clarke 1 collaboration

Lussia Kim 1 collaboration

Laura Tiseo 1 collaboration

Massimo Morfini 1 collaboration

Taneya Hossain 1 collaboration

Margaret L Rand 1 collaboration

Christine Brown 1 collaboration

David Lillicrap 1 collaboration

Victor S Blanchette 1 collaboration

Raphaël Crépin 1 collaboration

Brigitte Tardy 1 collaboration

Thierry Lambert 1 collaboration

Pierre Chamouni 1 collaboration

Marc Trossaert 1 collaboration

Ségolène Claeyssens 1 collaboration

Claire Berger 1 collaboration

Laurent Ardillon 1 collaboration

Valérie Gay 1 collaboration

Xavier Delavenne 1 collaboration

Annie Harroche 1 collaboration

Mohamed Aborig 1 collaboration

Shruti Nambiar 1 collaboration

Johnson Darko 1 collaboration

Anthony Mutsaers 1 collaboration

Andre Fleck 1 collaboration

Ernest Osei 1 collaboration

Shawn Wettig 1 collaboration

Pauline Damien 1 collaboration

Michèle Piot 1 collaboration

Michel Cournil 1 collaboration

Anne Lienhart 1 collaboration

Fabienne Genre-Volot 1 collaboration

Hervé Chambost 1 collaboration

Fatemeh Keyvani 1 collaboration

Peyman GhavamiNejad 1 collaboration

Mahmoud Ayman Saleh 1 collaboration

Mohammad Soltani 1 collaboration

Yusheng Zhao 1 collaboration

Sadegh Sadeghzadeh 1 collaboration

Arash Shakeri 1 collaboration

Hanjia Zheng 1 collaboration

Fasih A Rahman 1 collaboration

Sarah Mahshid 1 collaboration

Joe Quadrilatero 1 collaboration

Praveen P N Rao 1 collaboration

Mahla Poudineh 1 collaboration

A Tokarev 1 collaboration

Gary Foster 1 collaboration

A Bouchnita 1 collaboration

M Marion 1 collaboration

M Panteleev 1 collaboration

D Nechipurenko 1 collaboration

Jan Astermark 1 collaboration

Anna Olsson 1 collaboration

Kinga Täckström 1 collaboration

Maria Walger 1 collaboration

Maria Magnusson 1 collaboration

Mohammed Mahdi 1 collaboration

Stuart Young 1 collaboration

Josh Silvertown 1 collaboration

Margaret H Goggans 1 collaboration

Patricia J Barker 1 collaboration

Timothy W Jacobs 1 collaboration

Ellis J Neufeld 1 collaboration

Ulrike M Reiss 1 collaboration

John C Panetta 1 collaboration

Stacy E Croteau 1 collaboration

Jennifer Lissick 1 collaboration

Vinod Balasa 1 collaboration

Christina Ashburner 1 collaboration

Young Shil Park 1 collaboration

Juan Eduardo Megías-Vericat 1 collaboration

Azusa Nagao 1 collaboration

Tung Wynn 1 collaboration

Fernando Corrales-Medina 1 collaboration

Huyen Tran 1 collaboration

Anjali Sharathkumar 1 collaboration

Meera Chitlur 1 collaboration

Samuel Sarmiento 1 collaboration

Claire Pouplard 1 collaboration

Laurent Sattler 1 collaboration

Anne Ryman 1 collaboration

Valérie Eschwege 1 collaboration

Emmanuel De Maistre 1 collaboration

Claire Flaujac 1 collaboration

Jean Szymezak 1 collaboration

François Grand 1 collaboration

Yohann Repesse 1 collaboration

Hubert Galinat 1 collaboration

Magali Donnard 1 collaboration

Catherine Ternisien 1 collaboration

Emmanuelle Jeanpierre 1 collaboration

Omnia Salah Heikal 1 collaboration

Patrick F van Rheenen 1 collaboration

Daan J Touw 1 collaboration

Jos G W Kosterink 1 collaboration

Marina Maurer 1 collaboration

Jeroen V Koomen 1 collaboration

Paola Mian 1 collaboration

Davide Matino 1 collaboration

Anthony K C Chan 1 collaboration

Kay Decker 1 collaboration

Olayide Oladoyinbo 1 collaboration

Elisabetta Trinari 1 collaboration