Ralph Gradisch

Affiliations

Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

Publications (9)

Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain.

The Journal of biological chemistry

Avec: Ralph Gradisch , Dániel Szöllősi , Marco Niello , Erika Lazzarin , Harald H Sitte , Thomas Stockner

Persistent binding at dopamine transporters determines sustained psychostimulant effects.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Marco Niello , Spyridon Sideromenos , Ralph Gradisch , Ronan O Shea , Jakob Schwazer , Julian Maier , Nina Kastner , Walter Sandtner , Kathrin Jäntsch , Carl R Lupica , Alexander F Hoffman , Gert Lubec , Claus J Loland , Thomas Stockner , Daniela D Pollak , Michael H Baumann , Harald H Sitte

Unveiling the crucial role of betaine: modulation of GABA homeostasis via SLC6A1 transporter (GAT1).

Cellular and molecular life sciences : CMLS

Avec: Manan Bhatt , Erika Lazzarin , Ana Sofia Alberto-Silva , Guido Domingo , Rocco Zerlotti , Ralph Gradisch , Andre Bazzone , Harald H Sitte , Thomas Stockner , Elena Bossi

De novo variants in GABRA4 are associated with a neurological phenotype including developmental delay, behavioral abnormalities and epilepsy.

European journal of human genetics : EJHG

Avec: Samin A Sajan , Ralph Gradisch , Florian D Vogel , Alison J Coffey , Daria Salyakina , Diana Soler , Parul Jayakar , Anuj Jayakar , Simona E Bianconi , Annina H Cooper , Shuxi Liu , Nancy William , Ira Benkel-Herrenbrück , Robert Maiwald , Corina Heller , Saskia Biskup , Steffen Leiz , Dominik S Westphal , Matias Wagner , Amy Clarke , Thomas Stockner , Margot Ernst , Akanchha Kesari , Martin Krenn

Structural basis of organic cation transporter-3 inhibition.

Nature communications

Avec: Basavraj Khanppnavar , Julian Maier , Freja Herborg , Ralph Gradisch , Erika Lazzarin , Dino Luethi , Jae-Won Yang , Chao Qi , Marion Holy , Kathrin Jäntsch , Oliver Kudlacek , Klaus Schicker , Thomas Werge , Ulrik Gether , Thomas Stockner , Volodymyr M Korkhov , Harald H Sitte

The role of the degenerate nucleotide binding site in type I ABC exporters.

FEBS letters

Avec: Thomas Stockner , Ralph Gradisch , Lutz Schmitt

Allosteric Modulation of Neurotransmitter Transporters as a Therapeutic Strategy.

Trends in pharmacological sciences

Avec: Marco Niello , Ralph Gradisch , Claus Juul Loland , Thomas Stockner , Harald H Sitte

Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors.

Nature communications

Avec: Ralph Gradisch , Katharina Schlögl , Erika Lazzarin , Marco Niello , Julian Maier , Felix P Mayer , Leticia Alves da Silva , Sophie M C Skopec , Randy D Blakely , Harald H Sitte , Marko D Mihovilovic , Thomas Stockner

Free energy profile of the substrate-induced occlusion of the human serotonin transporter.

Journal of neurochemistry

Avec: Leticia Alves da Silva , Erika Lazzarin , Ralph Gradisch , Amy Clarke , Thomas Stockner

Réseau de co-auteurs

Thomas Stockner 9 collaborations

Harald H Sitte 6 collaborations

Erika Lazzarin 5 collaborations

Marco Niello 4 collaborations

Julian Maier 3 collaborations

Kathrin Jäntsch 2 collaborations

Amy Clarke 2 collaborations

Leticia Alves da Silva 2 collaborations

Dániel Szöllősi 1 collaboration

Spyridon Sideromenos 1 collaboration

Ronan O Shea 1 collaboration

Jakob Schwazer 1 collaboration

Nina Kastner 1 collaboration

Walter Sandtner 1 collaboration

Carl R Lupica 1 collaboration

Alexander F Hoffman 1 collaboration

Gert Lubec 1 collaboration

Claus J Loland 1 collaboration

Daniela D Pollak 1 collaboration

Michael H Baumann 1 collaboration

Manan Bhatt 1 collaboration

Ana Sofia Alberto-Silva 1 collaboration

Guido Domingo 1 collaboration

Rocco Zerlotti 1 collaboration

Andre Bazzone 1 collaboration

Elena Bossi 1 collaboration

Samin A Sajan 1 collaboration

Florian D Vogel 1 collaboration

Alison J Coffey 1 collaboration

Daria Salyakina 1 collaboration

Diana Soler 1 collaboration

Parul Jayakar 1 collaboration

Anuj Jayakar 1 collaboration

Simona E Bianconi 1 collaboration

Annina H Cooper 1 collaboration

Shuxi Liu 1 collaboration

Nancy William 1 collaboration

Ira Benkel-Herrenbrück 1 collaboration

Robert Maiwald 1 collaboration

Corina Heller 1 collaboration

Saskia Biskup 1 collaboration

Steffen Leiz 1 collaboration

Dominik S Westphal 1 collaboration

Matias Wagner 1 collaboration

Margot Ernst 1 collaboration

Akanchha Kesari 1 collaboration

Martin Krenn 1 collaboration

Basavraj Khanppnavar 1 collaboration

Freja Herborg 1 collaboration

Dino Luethi 1 collaboration

Jae-Won Yang 1 collaboration

Chao Qi 1 collaboration

Marion Holy 1 collaboration

Oliver Kudlacek 1 collaboration

Klaus Schicker 1 collaboration

Thomas Werge 1 collaboration

Ulrik Gether 1 collaboration

Volodymyr M Korkhov 1 collaboration

Lutz Schmitt 1 collaboration

Claus Juul Loland 1 collaboration

Katharina Schlögl 1 collaboration

Felix P Mayer 1 collaboration

Sophie M C Skopec 1 collaboration

Randy D Blakely 1 collaboration

Marko D Mihovilovic 1 collaboration