Raphael Boutry

Affiliations

Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8199-EGID, 59000, Lille, France.

Publications (12)

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development.

Cellular and molecular life sciences : CMLS

Avec: Mathie Tenenbaum , Valérie Plaisance , Raphael Boutry , Valérie Pawlowski , Cécile Jacovetti , Clara Sanchez-Parra , Hélène Ezanno , Julien Bourry , Nicole Beeler , Gianni Pasquetti , Valery Gmyr , Stéphane Dalle , Julie Kerr-Conte , François Pattou , Syu-Ichi Hirai , Romano Regazzi , Amélie Bonnefond , Philippe Froguel , Amar Abderrahmani

Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect.

Clinical epigenetics

Avec: Amna Khamis , Raphael Boutry , Mickaël Canouil , Sumi Mathew , Stephane Lobbens , Hutokshi Crouch , Toby Andrew , Amar Abderrahmani , Filippo Tamanini , Philippe Froguel

Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function.

Nature communications

Avec: Sarah Meulebrouck , Judith Merrheim , Gurvan Queniat , Cyril Bourouh , Mehdi Derhourhi , Mathilde Boissel , Xiaoyan Yi , Alaa Badreddine , Raphaël Boutry , Audrey Leloire , Bénédicte Toussaint , Souhila Amanzougarene , Emmanuel Vaillant , Emmanuelle Durand , Hélène Loiselle , Marlène Huyvaert , Aurélie Dechaume , Victoria Scherrer , Piero Marchetti , Beverley Balkau , Guillaume Charpentier , Sylvia Franc , Michel Marre , Ronan Roussel , Raphaël Scharfmann , Miriam Cnop , Mickaël Canouil , Morgane Baron , Philippe Froguel , Amélie Bonnefond

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.

Nature medicine

Avec: Morgane Baron , Julie Maillet , Marlène Huyvaert , Aurélie Dechaume , Raphaël Boutry , Hélène Loiselle , Emmanuelle Durand , Bénédicte Toussaint , Emmanuel Vaillant , Julien Philippe , Jérémy Thomas , Amjad Ghulam , Sylvia Franc , Guillaume Charpentier , Jean-Michel Borys , Claire Lévy-Marchal , Maïthé Tauber , Raphaël Scharfmann , Jacques Weill , Cécile Aubert , Julie Kerr-Conte , François Pattou , Ronan Roussel , Beverley Balkau , Michel Marre , Mathilde Boissel , Mehdi Derhourhi , Stefan Gaget , Mickaël Canouil , Philippe Froguel , Amélie Bonnefond

The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells.

Cell reports

Avec: Cyril Bourouh , Emilie Courty , Laure Rolland , Gianni Pasquetti , Xavier Gromada , Nabil Rabhi , Charlène Carney , Maeva Moreno , Raphaël Boutry , Emilie Caron , Zohra Benfodda , Patrick Meffre , Julie Kerr-Conte , François Pattou , Philippe Froguel , Amélie Bonnefond , Frédérik Oger , Jean-Sébastien Annicotte

Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes.

Diabetes care

Avec: Lise Folon , Morgane Baron , Victoria Scherrer , Bénédicte Toussaint , Emmanuel Vaillant , Hélène Loiselle , Aurélie Dechaume , Frédérique De Pooter , Raphaël Boutry , Mathilde Boissel , Aboubacar Diallo , Lijiao Ning , Beverley Balkau , Guillaume Charpentier , Sylvia Franc , Michel Marre , Mehdi Derhourhi , Philippe Froguel , Amélie Bonnefond

PNLIPRP1 hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol metabolism.

Diabetes

Avec: Lucas Maurin , Lorella Marselli , Mathilde Boissel , Lijiao Ning , Raphael Boutry , Justine Fernandes , Mara Suleiman , Carmela De Luca , Audrey Leloire , Vincent Pascat , Bénédicte Toussaint , Souhila Amanzougarene , Mehdi Derhourhi , Anne Jörns , Sigurd Lenzen , François Pattou , Julie Kerr-Conte , Mickaël Canouil , Piero Marchetti , Amélie Bonnefond , Philippe Froguel , Amna Khamis

Exploring the Role of Purinergic Receptor P2RY1 in Type 2 Diabetes Risk and Pathophysiology: Insights from Human Functional Genomics.

Molecular metabolism

Avec: Arnaud Dance , Justine Fernandes , Bénédicte Toussaint , Emmanuel Vaillant , Raphaël Boutry , Morgane Baron , Hélène Loiselle , Beverley Balkau , Guillaume Charpentier , Sylvia Franc , Mark Ibberson , Michel Marre , Marie Gernay , Marjorie Fadeur , Nicolas Paquot , Martine Vaxillaire , Mathilde Boissel , Souhila Amanzougarene , Mehdi Derhourhi , Amna Khamis , Philippe Froguel , Amélie Bonnefond

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas.

Diabetologia

Avec: Sarah Meulebrouck , Victoria Scherrer , Raphaël Boutry , Bénédicte Toussaint , Emmanuel Vaillant , Aurélie Dechaume , Hélène Loiselle , Beverley Balkau , Guillaume Charpentier , Sylvia Franc , Michel Marre , Morgane Baron , Martine Vaxillaire , Mehdi Derhourhi , Mathilde Boissel , Philippe Froguel , Amélie Bonnefond

Timed use of digoxin prevents heart ischemia-reperfusion injury through a REV-ERBα-UPS signaling pathway.

Nature cardiovascular research

Avec: Manjula Vinod , Alexandre Berthier , Xavier Maréchal , Céline Gheeraert , Raphaёl Boutry , Stéphane Delhaye , Jean-Sébastien Annicotte , Hélène Duez , Agnès Hovasse , Sarah Cianférani , David Montaigne , Jérôme Eeckhoute , Bart Staels , Philippe Lefebvre

Knocking Down

Cells

Avec: Yasmina Kahoul , Xi Yao , Frédérik Oger , Maeva Moreno , Souhila Amanzougarene , Mehdi Derhourhi , Emmanuelle Durand , Raphael Boutry , Amélie Bonnefond , Philippe Froguel , Christian Dani , Jean-Sébastien Annicotte , Christophe Breton

Control of human pancreatic beta cell kinome by glucagon-like peptide-1 receptor biased agonism.

Diabetes, obesity & metabolism

Avec: Jiannan Xiao , Liliane El Eid , Teresa Buenaventura , Raphaël Boutry , Amélie Bonnefond , Ben Jones , Guy A Rutter , Philippe Froguel , Alejandra Tomas

Réseau de co-auteurs

Philippe Froguel 11 collaborations

Amélie Bonnefond 10 collaborations

Mehdi Derhourhi 7 collaborations

Raphaël Boutry 7 collaborations

Mathilde Boissel 6 collaborations

Bénédicte Toussaint 6 collaborations

Emmanuel Vaillant 5 collaborations

Hélène Loiselle 5 collaborations

Beverley Balkau 5 collaborations

Guillaume Charpentier 5 collaborations

Sylvia Franc 5 collaborations

Michel Marre 5 collaborations

Morgane Baron 5 collaborations

Julie Kerr-Conte 4 collaborations

François Pattou 4 collaborations

Mickaël Canouil 4 collaborations

Souhila Amanzougarene 4 collaborations

Aurélie Dechaume 4 collaborations

Amna Khamis 3 collaborations

Emmanuelle Durand 3 collaborations

Victoria Scherrer 3 collaborations

Jean-Sébastien Annicotte 3 collaborations

Gianni Pasquetti 2 collaborations

Amar Abderrahmani 2 collaborations

Sarah Meulebrouck 2 collaborations

Cyril Bourouh 2 collaborations

Audrey Leloire 2 collaborations

Marlène Huyvaert 2 collaborations

Piero Marchetti 2 collaborations

Ronan Roussel 2 collaborations

Raphaël Scharfmann 2 collaborations

Maeva Moreno 2 collaborations

Frédérik Oger 2 collaborations

Lijiao Ning 2 collaborations

Justine Fernandes 2 collaborations

Martine Vaxillaire 2 collaborations

Mathie Tenenbaum 1 collaboration

Valérie Plaisance 1 collaboration

Valérie Pawlowski 1 collaboration

Cécile Jacovetti 1 collaboration

Clara Sanchez-Parra 1 collaboration

Hélène Ezanno 1 collaboration

Julien Bourry 1 collaboration

Nicole Beeler 1 collaboration

Valery Gmyr 1 collaboration

Stéphane Dalle 1 collaboration

Syu-Ichi Hirai 1 collaboration

Romano Regazzi 1 collaboration

Sumi Mathew 1 collaboration

Stephane Lobbens 1 collaboration

Hutokshi Crouch 1 collaboration

Toby Andrew 1 collaboration

Filippo Tamanini 1 collaboration

Judith Merrheim 1 collaboration

Gurvan Queniat 1 collaboration

Xiaoyan Yi 1 collaboration

Alaa Badreddine 1 collaboration

Miriam Cnop 1 collaboration

Julie Maillet 1 collaboration

Julien Philippe 1 collaboration

Jérémy Thomas 1 collaboration

Amjad Ghulam 1 collaboration

Jean-Michel Borys 1 collaboration

Claire Lévy-Marchal 1 collaboration

Maïthé Tauber 1 collaboration

Jacques Weill 1 collaboration

Cécile Aubert 1 collaboration

Stefan Gaget 1 collaboration

Emilie Courty 1 collaboration

Laure Rolland 1 collaboration

Xavier Gromada 1 collaboration

Nabil Rabhi 1 collaboration

Charlène Carney 1 collaboration

Emilie Caron 1 collaboration

Zohra Benfodda 1 collaboration

Patrick Meffre 1 collaboration

Lise Folon 1 collaboration

Frédérique De Pooter 1 collaboration

Aboubacar Diallo 1 collaboration

Lucas Maurin 1 collaboration

Lorella Marselli 1 collaboration

Mara Suleiman 1 collaboration

Carmela De Luca 1 collaboration

Vincent Pascat 1 collaboration

Anne Jörns 1 collaboration

Sigurd Lenzen 1 collaboration

Arnaud Dance 1 collaboration

Mark Ibberson 1 collaboration

Marie Gernay 1 collaboration

Marjorie Fadeur 1 collaboration

Nicolas Paquot 1 collaboration

Manjula Vinod 1 collaboration

Alexandre Berthier 1 collaboration

Xavier Maréchal 1 collaboration

Céline Gheeraert 1 collaboration

Raphaёl Boutry 1 collaboration

Stéphane Delhaye 1 collaboration

Hélène Duez 1 collaboration

Agnès Hovasse 1 collaboration

Sarah Cianférani 1 collaboration

David Montaigne 1 collaboration

Jérôme Eeckhoute 1 collaboration

Bart Staels 1 collaboration

Philippe Lefebvre 1 collaboration

Yasmina Kahoul 1 collaboration

Xi Yao 1 collaboration

Christian Dani 1 collaboration

Christophe Breton 1 collaboration

Jiannan Xiao 1 collaboration

Liliane El Eid 1 collaboration

Teresa Buenaventura 1 collaboration

Ben Jones 1 collaboration

Guy A Rutter 1 collaboration

Alejandra Tomas 1 collaboration