Robyn Meech

Affiliations

Department of Clinical Pharmacology and Flinders Cancer Centre, Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia. Electronic address: robyn.meech@flinders.edu.au.

Publications (24)

The UGTome: The expanding diversity of UDP glycosyltransferases and its impact on small molecule metabolism.

Pharmacology & therapeutics

Avec: Dong Gui Hu , J Ulie-Ann Hulin , Pramod C Nair , Alex Z Haines , Ross A McKinnon , Peter I Mackenzie , Robyn Meech

The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms.

Physiological reviews

Avec: Robyn Meech , Dong Gui Hu , Ross A McKinnon , Siti Nurul Mubarokah , Alex Z Haines , Pramod C Nair , Andrew Rowland , Peter I Mackenzie

Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.

Investigative ophthalmology & visual science

Avec: Emma N Finburgh , Olivier Mauduit , Takako Noguchi , Jennifer J Bu , Anser A Abbas , Dominic F Hakim , Saverio Bellusci , Robyn Meech , Helen P Makarenkova , Natalie A Afshari

Wnt/β-catenin signaling induces the myomiRs miR-133b and miR-206 to suppress Pax7 and induce the myogenic differentiation program.

Journal of cellular biochemistry

Avec: Shuang Cui , Liang Li , Siti Nurul Mubarokah , Robyn Meech

Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres.

International journal of molecular sciences

Avec: Olga A Sukocheva , Dong Gui Hu , Robyn Meech , Anupam Bishayee

D-methionine administered as late as 36 hours post-noise exposure rescues from permanent threshold shift and dose-dependently increases serum antioxidant levels.

International journal of audiology

Avec: Kathleen C M Campbell , Nicole Cosenza , Robert Meech , Michael Buhnerkempe , Jun Qin , Leonard Rybak , Daniel J Fox

A Physiologically Based Pharmacokinetic Model to Predict Determinants of Variability in Epirubicin Exposure and Tissue Distribution.

Pharmaceutics

Avec: Radwan Ansaar , Robyn Meech , Andrew Rowland

The Somatic Mutation Landscape of UDP-Glycosyltransferase (

Cancers

Avec: Dong Gui Hu , Shashikanth Marri , Julie-Ann Hulin , Ross A McKinnon , Peter I Mackenzie , Robyn Meech

Isolation and Propagation of Lacrimal Gland Putative Epithelial Progenitor Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Helen P Makarenkova , Robyn Meech

The Expression Profiles of ADME Genes in Human Cancers and Their Associations with Clinical Outcomes.

Cancers

Avec: Dong Gui Hu , Peter I Mackenzie , Pramod C Nair , Ross A McKinnon , Robyn Meech

D-methionine immediate and continued rescue after noise exposure does not prevent temporary threshold shift but alters cochlear and serum antioxidant levels.

International journal of audiology

Avec: Kathleen C M Campbell , Nicole Cosenza , Robert Meech , Michael Buhnerkempe , Jun Qin , Leonard Rybak , Daniel J Fox

A Comprehensive Bioinformatic Analysis of RNA-seq Datasets Reveals a Differential and Variable Expression of Wildtype and Variant UGT1A Transcripts in Human Tissues and Their Deregulation in Cancers.

Cancers

Avec: Dong Gui Hu , Shashikanth Marri , Julie-Ann Hulin , Ross A McKinnon , Peter I Mackenzie , Robyn Meech

Plasma extracellular nanovesicle (exosome)-derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure.

British journal of clinical pharmacology

Avec: Andrew Rowland , Warit Ruanglertboon , Madelé van Dyk , Dhilushi Wijayakumara , Linda S Wood , Robyn Meech , Peter I Mackenzie , A David Rodrigues , Jean-Claude Marshall , Michael J Sorich

Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma.

The Journal of pharmacology and experimental therapeutics

Avec: Dong Gui Hu , Shashikanth Marri , Ross A McKinnon , Peter I Mackenzie , Robyn Meech

Circular RNAs of UDP-Glycosyltransferase (

Molecular pharmacology

Avec: Dong Gui Hu , Peter I Mackenzie , Julie-Ann Hulin , Ross A McKinnon , Robyn Meech

Integrative Transcriptomic Network Analysis of Butyrate Treated Colorectal Cancer Cells.

Cancers

Avec: Saira R Ali , Ayla Orang , Shashikanth Marri , Ross A McKinnon , Robyn Meech , Michael Z Michael

Regulation of human UDP-glycosyltransferase (

Drug metabolism reviews

Avec: Dong Gui Hu , Peter I Mackenzie , Julie-Ann Hulin , Ross A McKinnon , Robyn Meech

The Expression Profiles and Deregulation of UDP-Glycosyltransferase (

Cancers

Avec: Dong Gui Hu , Shashikanth Marri , Peter I Mackenzie , Julie-Ann Hulin , Ross A McKinnon , Robyn Meech

Activation of Cryptic Donor Splice Sites Within the UGT1A First-Exon Region Generates Variant Transcripts That Encode UGT1A Proteins With Truncated Aglycone-binding Domains.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Dong Gui Hu , Shashikanth Marri , Julie-Ann Hulin , Radwan Ansaar , Peter I Mackenzie , Ross A McKinnon , Robyn Meech

β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin.

Development (Cambridge, England)

Avec: Shuang Cui , Liang Li , Ruth T Yu , Michael Downes , Ronald M Evans , Julie-Ann Hulin , Helen P Makarenkova , Robyn Meech

Pannexin 1 Regulates Skeletal Muscle Regeneration by Promoting Bleb-Based Myoblast Migration and Fusion Through a Novel Lipid Based Signaling Mechanism.

Frontiers in cell and developmental biology

Avec: Katia Suarez-Berumen , Henry Collins-Hooper , Anastasia Gromova , Robyn Meech , Alessandra Sacco , Phil R Dash , Robert Mitchell , Valery I Shestopalov , Thomas E Woolley , Sakthivel Vaiyapuri , Ketan Patel , Helen P Makarenkova

Preloaded D-methionine protects from steady state and impulse noise-induced hearing loss and induces long-term cochlear and endogenous antioxidant effects.

PloS one

Avec: Kathleen Campbell , Nicole Cosenza , Robert Meech , Michael Buhnerkempe , Jun Qin , Leonard Rybak , Daniel Fox

Functional high-throughput screen identifies microRNAs that promote butyrate-induced death in colorectal cancer cells.

Molecular therapy. Nucleic acids

Avec: Saira R Ali , Karen J Humphreys , Kaylene J Simpson , Ross A McKinnon , Robyn Meech , Michael Z Michael

Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance.

Pharmacology & therapeutics

Avec: John O Miners , Thomas M Polasek , Julie-Ann Hulin , Andrew Rowland , Robyn Meech

Réseau de co-auteurs

Ross A McKinnon 12 collaborations

Dong Gui Hu 11 collaborations

Peter I Mackenzie 11 collaborations

Julie-Ann Hulin 8 collaborations

Shashikanth Marri 6 collaborations

Andrew Rowland 4 collaborations

Helen P Makarenkova 4 collaborations

Pramod C Nair 3 collaborations

Nicole Cosenza 3 collaborations

Robert Meech 3 collaborations

Michael Buhnerkempe 3 collaborations

Jun Qin 3 collaborations

Leonard Rybak 3 collaborations

Alex Z Haines 2 collaborations

Siti Nurul Mubarokah 2 collaborations

Shuang Cui 2 collaborations

Liang Li 2 collaborations

Kathleen C M Campbell 2 collaborations

Daniel J Fox 2 collaborations

Radwan Ansaar 2 collaborations

Saira R Ali 2 collaborations

Michael Z Michael 2 collaborations

J Ulie-Ann Hulin 1 collaboration

Emma N Finburgh 1 collaboration

Olivier Mauduit 1 collaboration

Takako Noguchi 1 collaboration

Jennifer J Bu 1 collaboration

Anser A Abbas 1 collaboration

Dominic F Hakim 1 collaboration

Saverio Bellusci 1 collaboration

Natalie A Afshari 1 collaboration

Olga A Sukocheva 1 collaboration

Anupam Bishayee 1 collaboration

Warit Ruanglertboon 1 collaboration

Madelé van Dyk 1 collaboration

Dhilushi Wijayakumara 1 collaboration

Linda S Wood 1 collaboration

A David Rodrigues 1 collaboration

Jean-Claude Marshall 1 collaboration

Michael J Sorich 1 collaboration

Ayla Orang 1 collaboration

Ruth T Yu 1 collaboration

Michael Downes 1 collaboration

Ronald M Evans 1 collaboration

Katia Suarez-Berumen 1 collaboration

Henry Collins-Hooper 1 collaboration

Anastasia Gromova 1 collaboration

Alessandra Sacco 1 collaboration

Phil R Dash 1 collaboration

Robert Mitchell 1 collaboration

Valery I Shestopalov 1 collaboration

Thomas E Woolley 1 collaboration

Sakthivel Vaiyapuri 1 collaboration

Ketan Patel 1 collaboration

Kathleen Campbell 1 collaboration

Daniel Fox 1 collaboration

Karen J Humphreys 1 collaboration

Kaylene J Simpson 1 collaboration

John O Miners 1 collaboration

Thomas M Polasek 1 collaboration