Ron Daniel Jachimowicz

Affiliations

University of Cologne,University Hospital Cologne, Cologne, Germany.

Publications (18)

Genomic Amplification of

Cells

Avec: Yuta Kobayashi , Matias A Bustos , Yoshiaki Shoji , Ron D Jachimowicz , Yosef Shiloh , Dave S B Hoon

An inducible Cd79b mutation confers ibrutinib sensitivity in mouse models of Myd88-driven diffuse large B-cell lymphoma.

Blood advances

Avec: Ruth Flümann , Julia Hansen , Jörn Meinel , Pauline Pfeiffer , Hannah Goldfarb Wittkopf , Anna Lütz , Jessica Wirtz , Michael Möllmann , Tanja Zhou , Areya Tabatabai , Tim Lohmann , Maximilian Jauch , Filippo Beleggia , Benedikt Pelzer , Fabian Ullrich , Svenja Höfmann , Aastha Arora , Thorsten Persigehl , Reinhard Buettner , Bastian von Tresckow , Sebastian Klein , Ron D Jachimowicz , H Christian Reinhardt , Gero Knittel

Biallelic variants in CRIPT cause a Rothmund-Thomson-like syndrome with increased cellular senescence.

Genetics in medicine : official journal of the American College of Medical Genetics

Avec: Luisa Averdunk , Maxim A Huetzen , Daniel Moreno-Andrés , Reinhard Kalb , Shane McKee , Tzung-Chien Hsieh , Annette Seibt , Marten Schouwink , Seema Lalani , Eissa Ali Faqeih , Theresa Brunet , Peter Boor , Kornelia Neveling , Alexander Hoischen , Barbara Hildebrandt , Elisabeth Graf , Linchao Lu , Weidong Jin , Joerg Schaper , Jamal A Omer , Tanguy Demaret , Nicole Fleischer , Detlev Schindler , Peter Krawitz , Ertan Mayatepek , Dagmar Wieczorek , Lisa L Wang , Wolfram Antonin , Ron D Jachimowicz , Verena von Felbert , Felix Distelmaier

Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE): a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network.

Lancet (London, England)

Avec: Martin Dreyling , Jeanette Doorduijn , Eva Giné , Mats Jerkeman , Jan Walewski , Martin Hutchings , Ulrich Mey , Jon Riise , Marek Trneny , Vibeke Vergote , Ofer Shpilberg , Maria Gomes da Silva , Sirpa Leppä , Linmiao Jiang , Stephan Stilgenbauer , Andrea Kerkhoff , Ron D Jachimowicz , Melania Celli , Georg Hess , Luca Arcaini , Carlo Visco , Tom van Meerten , Stefan Wirths , Pier Luigi Zinzani , Urban Novak , Peter Herhaus , Fabio Benedetti , Kristina Sonnevi , Christine Hanoun , Matthias Hänel , Judith Dierlamm , Christiane Pott , Wolfram Klapper , Döndü Gözel , Christian Schmidt , Michael Unterhalt , Marco Ladetto , Eva Hoster

Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP.

Haematologica

Avec: Ron Daniel Jachimowicz , Luise Pieper , Sarah Reinke , Artur Gontarewicz , Annette Plütschow , Heinz Haverkamp , Leonie Frauenfeld , Falko Fend , Mathis Overkamp , Franziska Jochims , Christoph Thorns , Martin Leo Hansmann , Peter Möller , Andreas Rosenwald , Harald Stein , Hans Christian Reinhardt , Peter Borchmann , Bastian von Tresckow , Andreas Engert , Wolfram Klapper

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.

Nature communications

Avec: Marcel A Dammert , Johannes Brägelmann , Rachelle R Olsen , Stefanie Böhm , Niloufar Monhasery , Christopher P Whitney , Milind D Chalishazar , Hannah L Tumbrink , Matthew R Guthrie , Sebastian Klein , Abbie S Ireland , Jeremy Ryan , Anna Schmitt , Annika Marx , Luka Ozretić , Roberta Castiglione , Carina Lorenz , Ron D Jachimowicz , Elmar Wolf , Roman K Thomas , John T Poirier , Reinhard Büttner , Triparna Sen , Lauren A Byers , H Christian Reinhardt , Anthony Letai , Trudy G Oliver , Martin L Sos

Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma.

Molecular oncology

Avec: Tomohiro Murakami , Yoshiaki Shoji , Tomohiko Nishi , Shu-Ching Chang , Ron D Jachimowicz , Sojun Hoshimoto , Shigeshi Ono , Yosef Shiloh , Hiroya Takeuchi , Yuko Kitagawa , Dave S B Hoon , Matias A Bustos

Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients.

International journal of cancer

Avec: Rabea Wagener , Danielle Brandes , Marie Jung , Maxim A Huetzen , Anke K Bergmann , Stephanie Panier , Daniel Picard , Ute Fischer , Ron D Jachimowicz , Arndt Borkhardt , Triantafyllia Brozou

Mouse models of diffuse large B cell lymphoma.

Frontiers in immunology

Avec: Areya Tabatabai , Aastha Arora , Svenja Höfmann , Maximilian Jauch , Bastian von Tresckow , Julia Hansen , Ruth Flümann , Ron D Jachimowicz , Sebastian Klein , Hans Christian Reinhardt , Gero Knittel

UBQLN4 promotes non-homologous end joining by repressing DNA end-resection.

Molecular & cellular oncology

Avec: Ron D Jachimowicz , H Christian Reinhardt

Biallelic variants in YRDC cause a developmental disorder with progeroid features.

Human genetics

Avec: Julia Schmidt , Jonas Goergens , Tatiana Pochechueva , Annika Kotter , Niko Schwenzer , Maren Sitte , Gesa Werner , Janine Altmüller , Holger Thiele , Peter Nürnberg , Jörg Isensee , Yun Li , Christian Müller , Barbara Leube , H Christian Reinhardt , Tim Hucho , Gabriela Salinas , Mark Helm , Ron D Jachimowicz , Dagmar Wieczorek , Tobias Kohl , Stephan E Lehnart , Gökhan Yigit , Bernd Wollnik

Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination.

Infection

Avec: Marie-Lisa Hieber , Rosanne Sprute , Dennis A Eichenauer , Michael Hallek , Ron D Jachimowicz

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.

Blood cancer discovery

Avec: Ruth Flümann , Julia Hansen , Benedikt W Pelzer , Pascal Nieper , Tim Lohmann , Ilmars Kisis , Tobias Riet , Viktoria Kohlhas , Phuong-Hien Nguyen , Martin Peifer , Nima Abedpour , Graziella Bosco , Roman K Thomas , Moritz Kochanek , Jacqueline Knüfer , Lorenz Jonigkeit , Filippo Beleggia , Alessandra Holzem , Reinhard Büttner , Philipp Lohneis , Jörn Meinel , Monika Ortmann , Thorsten Persigehl , Michael Hallek , Dinis Pedro Calado , Markus Chmielewski , Sebastian Klein , Joachim R Göthert , Bjoern Chapuy , Branko Zevnik , F Thomas Wunderlich , Bastian von Tresckow , Ron D Jachimowicz , Ari M Melnick , Hans Christian Reinhardt , Gero Knittel

Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma.

Cells

Avec: Paul J Bröckelmann , Mathilde R W de Jong , Ron D Jachimowicz

DNA double-strand break repair pathway choice - from basic biology to clinical exploitation.

Cell cycle (Georgetown, Tex.)

Avec: Ron D Jachimowicz , Jonas Goergens , H Christian Reinhardt

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo.

Leukemia

Avec: Arina Riabinska , Daria Lehrmann , Ron Daniel Jachimowicz , Gero Knittel , Christian Fritz , Anna Schmitt , Aenne Geyer , Carola Heneweer , Maike Wittersheim , Lukas P Frenzel , Alessandro Torgovnick , Janica Lea Wiederstein , Claudia Maria Wunderlich , Monika Ortmann , Arlette Paillard , Wilhelm Wößmann , Arndt Borkhardt , Stefan Burdach , Martin-Leo Hansmann , Andreas Rosenwald , Sven Perner , Gita Mall , Wolfram Klapper , Andrea Merseburg , Marcus Krüger , Holger Grüll , Thorsten Persigehl , Frank Thomas Wunderlich , Martin Peifer , Olaf Utermöhlen , Reinhard Büttner , Filippo Beleggia , Hans Christian Reinhardt

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.

Cell

Avec: Ron D Jachimowicz , Filippo Beleggia , Jörg Isensee , Bhagya Bhavana Velpula , Jonas Goergens , Matias A Bustos , Markus A Doll , Anjana Shenoy , Cintia Checa-Rodriguez , Janica Lea Wiederstein , Keren Baranes-Bachar , Christoph Bartenhagen , Falk Hertwig , Nizan Teper , Tomohiko Nishi , Anna Schmitt , Felix Distelmaier , Hermann-Josef Lüdecke , Beate Albrecht , Marcus Krüger , Björn Schumacher , Tamar Geiger , Dave S B Hoon , Pablo Huertas , Matthias Fischer , Tim Hucho , Martin Peifer , Yael Ziv , H Christian Reinhardt , Dagmar Wieczorek , Yosef Shiloh

Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer.

Breast cancer research : BCR

Avec: Leonie Ratz , Chiara Brambillasca , Leandra Bartke , Maxim A Huetzen , Jonas Goergens , Orsolya Leidecker , Ron D Jachimowicz , Marieke van de Ven , Natalie Proost , Bjørn Siteur , Renske de Korte-Grimmerink , Peter Bouwman , Emilia M Pulver , Roebi de Bruijn , Jörg Isensee , Tim Hucho , Gaurav Pandey , Maarten van Lohuizen , Peter Mallmann , Hans Christian Reinhardt , Jos Jonkers , Julian Puppe

Réseau de co-auteurs

Ron D Jachimowicz 16 collaborations

H Christian Reinhardt 6 collaborations

Hans Christian Reinhardt 5 collaborations

Filippo Beleggia 4 collaborations

Bastian von Tresckow 4 collaborations

Sebastian Klein 4 collaborations

Gero Knittel 4 collaborations

Jonas Goergens 4 collaborations

Matias A Bustos 3 collaborations

Yosef Shiloh 3 collaborations

Dave S B Hoon 3 collaborations

Ruth Flümann 3 collaborations

Julia Hansen 3 collaborations

Thorsten Persigehl 3 collaborations

Maxim A Huetzen 3 collaborations

Dagmar Wieczorek 3 collaborations

Wolfram Klapper 3 collaborations

Anna Schmitt 3 collaborations

Reinhard Büttner 3 collaborations

Jörg Isensee 3 collaborations

Tim Hucho 3 collaborations

Martin Peifer 3 collaborations

Yoshiaki Shoji 2 collaborations

Jörn Meinel 2 collaborations

Areya Tabatabai 2 collaborations

Tim Lohmann 2 collaborations

Maximilian Jauch 2 collaborations

Svenja Höfmann 2 collaborations

Aastha Arora 2 collaborations

Felix Distelmaier 2 collaborations

Andreas Rosenwald 2 collaborations

Roman K Thomas 2 collaborations

Tomohiko Nishi 2 collaborations

Arndt Borkhardt 2 collaborations

Michael Hallek 2 collaborations

Monika Ortmann 2 collaborations

Janica Lea Wiederstein 2 collaborations

Marcus Krüger 2 collaborations

Yuta Kobayashi 1 collaboration

Pauline Pfeiffer 1 collaboration

Hannah Goldfarb Wittkopf 1 collaboration

Anna Lütz 1 collaboration

Jessica Wirtz 1 collaboration

Michael Möllmann 1 collaboration

Tanja Zhou 1 collaboration

Benedikt Pelzer 1 collaboration

Fabian Ullrich 1 collaboration

Reinhard Buettner 1 collaboration

Luisa Averdunk 1 collaboration

Daniel Moreno-Andrés 1 collaboration

Reinhard Kalb 1 collaboration

Shane McKee 1 collaboration

Tzung-Chien Hsieh 1 collaboration

Annette Seibt 1 collaboration

Marten Schouwink 1 collaboration

Seema Lalani 1 collaboration

Eissa Ali Faqeih 1 collaboration

Theresa Brunet 1 collaboration

Peter Boor 1 collaboration

Kornelia Neveling 1 collaboration

Alexander Hoischen 1 collaboration

Barbara Hildebrandt 1 collaboration

Elisabeth Graf 1 collaboration

Linchao Lu 1 collaboration

Weidong Jin 1 collaboration

Joerg Schaper 1 collaboration

Jamal A Omer 1 collaboration

Tanguy Demaret 1 collaboration

Nicole Fleischer 1 collaboration

Detlev Schindler 1 collaboration

Peter Krawitz 1 collaboration

Ertan Mayatepek 1 collaboration

Lisa L Wang 1 collaboration

Wolfram Antonin 1 collaboration

Verena von Felbert 1 collaboration

Martin Dreyling 1 collaboration

Jeanette Doorduijn 1 collaboration

Eva Giné 1 collaboration

Mats Jerkeman 1 collaboration

Jan Walewski 1 collaboration

Martin Hutchings 1 collaboration

Ulrich Mey 1 collaboration

Jon Riise 1 collaboration

Marek Trneny 1 collaboration

Vibeke Vergote 1 collaboration

Ofer Shpilberg 1 collaboration

Maria Gomes da Silva 1 collaboration

Sirpa Leppä 1 collaboration

Linmiao Jiang 1 collaboration

Stephan Stilgenbauer 1 collaboration

Andrea Kerkhoff 1 collaboration

Melania Celli 1 collaboration

Georg Hess 1 collaboration

Luca Arcaini 1 collaboration

Carlo Visco 1 collaboration

Tom van Meerten 1 collaboration

Stefan Wirths 1 collaboration

Pier Luigi Zinzani 1 collaboration

Urban Novak 1 collaboration

Peter Herhaus 1 collaboration

Fabio Benedetti 1 collaboration

Kristina Sonnevi 1 collaboration

Christine Hanoun 1 collaboration

Matthias Hänel 1 collaboration

Judith Dierlamm 1 collaboration

Christiane Pott 1 collaboration

Döndü Gözel 1 collaboration

Christian Schmidt 1 collaboration

Michael Unterhalt 1 collaboration

Marco Ladetto 1 collaboration

Eva Hoster 1 collaboration

Luise Pieper 1 collaboration

Sarah Reinke 1 collaboration

Artur Gontarewicz 1 collaboration

Annette Plütschow 1 collaboration

Heinz Haverkamp 1 collaboration

Leonie Frauenfeld 1 collaboration

Falko Fend 1 collaboration

Mathis Overkamp 1 collaboration

Franziska Jochims 1 collaboration

Christoph Thorns 1 collaboration

Martin Leo Hansmann 1 collaboration

Peter Möller 1 collaboration

Harald Stein 1 collaboration

Peter Borchmann 1 collaboration

Andreas Engert 1 collaboration

Marcel A Dammert 1 collaboration

Johannes Brägelmann 1 collaboration

Rachelle R Olsen 1 collaboration

Stefanie Böhm 1 collaboration

Niloufar Monhasery 1 collaboration

Christopher P Whitney 1 collaboration

Milind D Chalishazar 1 collaboration

Hannah L Tumbrink 1 collaboration

Matthew R Guthrie 1 collaboration

Abbie S Ireland 1 collaboration

Jeremy Ryan 1 collaboration

Annika Marx 1 collaboration

Luka Ozretić 1 collaboration

Roberta Castiglione 1 collaboration

Carina Lorenz 1 collaboration

Elmar Wolf 1 collaboration

John T Poirier 1 collaboration

Triparna Sen 1 collaboration

Lauren A Byers 1 collaboration

Anthony Letai 1 collaboration

Trudy G Oliver 1 collaboration

Martin L Sos 1 collaboration

Tomohiro Murakami 1 collaboration

Shu-Ching Chang 1 collaboration

Sojun Hoshimoto 1 collaboration

Shigeshi Ono 1 collaboration

Hiroya Takeuchi 1 collaboration

Yuko Kitagawa 1 collaboration

Rabea Wagener 1 collaboration

Danielle Brandes 1 collaboration

Marie Jung 1 collaboration

Anke K Bergmann 1 collaboration

Stephanie Panier 1 collaboration

Daniel Picard 1 collaboration

Ute Fischer 1 collaboration

Triantafyllia Brozou 1 collaboration

Julia Schmidt 1 collaboration

Tatiana Pochechueva 1 collaboration

Annika Kotter 1 collaboration

Niko Schwenzer 1 collaboration

Maren Sitte 1 collaboration

Gesa Werner 1 collaboration

Janine Altmüller 1 collaboration

Holger Thiele 1 collaboration

Peter Nürnberg 1 collaboration

Yun Li 1 collaboration

Christian Müller 1 collaboration

Barbara Leube 1 collaboration

Gabriela Salinas 1 collaboration

Mark Helm 1 collaboration

Tobias Kohl 1 collaboration

Stephan E Lehnart 1 collaboration

Gökhan Yigit 1 collaboration

Bernd Wollnik 1 collaboration

Marie-Lisa Hieber 1 collaboration

Rosanne Sprute 1 collaboration

Dennis A Eichenauer 1 collaboration

Benedikt W Pelzer 1 collaboration

Pascal Nieper 1 collaboration

Ilmars Kisis 1 collaboration

Tobias Riet 1 collaboration

Viktoria Kohlhas 1 collaboration

Phuong-Hien Nguyen 1 collaboration

Nima Abedpour 1 collaboration

Graziella Bosco 1 collaboration

Moritz Kochanek 1 collaboration

Jacqueline Knüfer 1 collaboration

Lorenz Jonigkeit 1 collaboration

Alessandra Holzem 1 collaboration

Philipp Lohneis 1 collaboration

Dinis Pedro Calado 1 collaboration

Markus Chmielewski 1 collaboration

Joachim R Göthert 1 collaboration

Bjoern Chapuy 1 collaboration

Branko Zevnik 1 collaboration

F Thomas Wunderlich 1 collaboration

Ari M Melnick 1 collaboration

Paul J Bröckelmann 1 collaboration

Mathilde R W de Jong 1 collaboration

Arina Riabinska 1 collaboration

Daria Lehrmann 1 collaboration

Christian Fritz 1 collaboration

Aenne Geyer 1 collaboration

Carola Heneweer 1 collaboration

Maike Wittersheim 1 collaboration

Lukas P Frenzel 1 collaboration

Alessandro Torgovnick 1 collaboration

Claudia Maria Wunderlich 1 collaboration

Arlette Paillard 1 collaboration

Wilhelm Wößmann 1 collaboration

Stefan Burdach 1 collaboration

Martin-Leo Hansmann 1 collaboration

Sven Perner 1 collaboration

Gita Mall 1 collaboration

Andrea Merseburg 1 collaboration

Holger Grüll 1 collaboration

Frank Thomas Wunderlich 1 collaboration

Olaf Utermöhlen 1 collaboration

Bhagya Bhavana Velpula 1 collaboration

Markus A Doll 1 collaboration

Anjana Shenoy 1 collaboration

Cintia Checa-Rodriguez 1 collaboration

Keren Baranes-Bachar 1 collaboration

Christoph Bartenhagen 1 collaboration

Falk Hertwig 1 collaboration

Nizan Teper 1 collaboration

Hermann-Josef Lüdecke 1 collaboration

Beate Albrecht 1 collaboration

Björn Schumacher 1 collaboration

Tamar Geiger 1 collaboration

Pablo Huertas 1 collaboration

Matthias Fischer 1 collaboration

Yael Ziv 1 collaboration

Leonie Ratz 1 collaboration

Chiara Brambillasca 1 collaboration

Leandra Bartke 1 collaboration

Orsolya Leidecker 1 collaboration

Marieke van de Ven 1 collaboration

Natalie Proost 1 collaboration

Bjørn Siteur 1 collaboration

Renske de Korte-Grimmerink 1 collaboration

Peter Bouwman 1 collaboration

Emilia M Pulver 1 collaboration

Roebi de Bruijn 1 collaboration

Gaurav Pandey 1 collaboration

Maarten van Lohuizen 1 collaboration

Peter Mallmann 1 collaboration

Jos Jonkers 1 collaboration

Julian Puppe 1 collaboration