Ruth Perets

Affiliations

Rambam Health Care Campus, Haifa, Israel.

Publications (20)

Pharmacokinetics of mitomycin-c lipidic prodrug entrapped in liposomes and clinical correlations in metastatic colorectal cancer patients.

Investigational new drugs

Avec: Alberto A Gabizon , Esther Tahover , Talia Golan , Ravit Geva , Ruth Perets , Yasmine Amitay , Hilary Shmeeda , Patricia Ohana

A phase 1a/1b trial of CSF-1R inhibitor LY3022855 in combination with durvalumab or tremelimumab in patients with advanced solid tumors.

Investigational new drugs

Avec: Gerald S Falchook , Marc Peeters , Sylvie Rottey , Luc Y Dirix , Radka Obermannova , Jonathan E Cohen , Ruth Perets , Ronnie Shapira Frommer , Todd M Bauer , Judy S Wang , Richard D Carvajal , Joshua Sabari , Sonya Chapman , Wei Zhang , Boris Calderon , Daniel A Peterson

PAX8 in the Junction between Development and Tumorigenesis.

International journal of molecular sciences

Avec: Reli Rachel Kakun , Zohar Melamed , Ruth Perets

Phase 2 study of the antitumour activity and safety of simlukafusp alfa (FAP-IL2v) combined with atezolizumab in patients with recurrent and/or metastatic cervical squamous cell carcinoma.

EBioMedicine

Avec: Loic Verlingue , Antoine Italiano , Hans Prenen , Eva Maria Guerra Alia , Diego Tosi , Ruth Perets , Iwona Lugowska , Vladimir Moiseyenko , Mahmut Gumus , Cagatay Arslan , Colin R Lindsay , Sanjeev Deva , Álvaro Taus , Ana Oaknin , Sylvie Rottey , Irfan Cicin , Sema Sezgin Goksu , Alexey Smolin , Susana Roselló-Keränen , Christin Habigt , Daniel Marbach , Christophe Boetsch , David Dejardin , Nassim Sleiman , Stefan Evers , Muriel Richard , Caroline Ardeshir , Jehad Charo , Anton Kraxner , Volker Teichgräber , Nino Keshelava , Rafal Dziadziuszko

Anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody quavonlimab in combination with pembrolizumab: Safety and efficacy from a phase I study in previously treated extensive-stage small cell lung cancer.

Lung cancer (Amsterdam, Netherlands)

Avec: Byoung Chul Cho , Kiyotaka Yoh , Ruth Perets , Adnan Nagrial , David R Spigel , Martin Gutierrez , Dong-Wan Kim , Dusan Kotasek , Drew Rasco , Jiaxin Niu , Miyako Satouchi , Myung-Ju Ahn , Dae Ho Lee , Corinne Maurice-Dror , Shabana Siddiqi , Yixin Ren , Rachel A Altura , Jair Bar

The KEYVIBE program: vibostolimab and pembrolizumab for the treatment of advanced malignancies.

Future oncology (London, England)

Avec: Ronnie Shapira-Frommer , Jiaxin Niu , Ruth Perets , Solange Peters , Geoffrey Shouse , Iwona Lugowska , Marina C Garassino , Jacob Sands , Tanya Keenan , Bin Zhao , Jane Healy , Myung-Ju Ahn

Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment.

Cell reports

Avec: Eleni Maniati , Chiara Berlato , Ganga Gopinathan , Owen Heath , Panoraia Kotantaki , Anissa Lakhani , Jacqueline McDermott , Colin Pegrum , Robin M Delaine-Smith , Oliver M T Pearce , Priyanka Hirani , Joash D Joy , Ludmila Szabova , Ruth Perets , Owen J Sansom , Ronny Drapkin , Peter Bailey , Frances R Balkwill

Radium-223 in combination with paclitaxel in cancer patients with bone metastases: safety results from an open-label, multicenter phase Ib study.

European journal of nuclear medicine and molecular imaging

Avec: Ravit Geva , Juanita Lopez , Sarah Danson , Heikki Joensuu , Avivit Peer , Samuel J Harris , Fabricio Souza , Kaline M C Pereira , Ruth Perets

Checkpoint Inhibitors in Gynecological Malignancies: Are we There Yet?

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Avec: Tarek Taha , Ari Reiss , Amnon Amit , Ruth Perets

First-in-Class Anti-immunoglobulin-like Transcript 4 Myeloid-Specific Antibody MK-4830 Abrogates a PD-1 Resistance Mechanism in Patients with Advanced Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Lillian L Siu , Ding Wang , John Hilton , Ravit Geva , Drew Rasco , Ruth Perets , Anson K Abraham , Douglas C Wilson , Julia F Markensohn , Jared Lunceford , Leah Suttner , Shabana Siddiqi , Rachel A Altura , Corinne Maurice-Dror

PAX8 plays an essential antiapoptotic role in uterine serous papillary cancer.

Oncogene

Avec: Basem Fares , Liron Berger , Einav Bangiev-Girsh , Reli Rachel Kakun , Dima Ghannam-Shahbari , Yuval Tabach , Yaniv Zohar , Eyal Gottlieb , Ruth Perets

FRACTION-RCC: nivolumab plus ipilimumab for advanced renal cell carcinoma after progression on immuno-oncology therapy.

Journal for immunotherapy of cancer

Avec: Toni K Choueiri , Harriet Kluger , Saby George , Scott S Tykodi , Timothy M Kuzel , Ruth Perets , Suresh Nair , Giuseppe Procopio , Michael A Carducci , Vincent Castonguay , Edmund Folefac , Chung-Han Lee , Sebastien J Hotte , Wilson H Miller , Shruti Shally Saggi , Chung-Wei Lee , Heshani Desilva , Prabhu Bhagavatheeswaran , Robert J Motzer , Bernard Escudier

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Hyun Cheol Chung , Willeke Ros , Jean-Pierre Delord , Ruth Perets , Antoine Italiano , Ronnie Shapira-Frommer , Lyudmila Manzuk , Sarina A Piha-Paul , Lei Xu , Susan Zeigenfuss , Scott K Pruitt , Alexandra Leary

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.

Nature

Avec: Mark A Eckert , Fabian Coscia , Agnieszka Chryplewicz , Jae Won Chang , Kyle M Hernandez , Shawn Pan , Samantha M Tienda , Dominik A Nahotko , Gang Li , Ivana Blaženović , Ricardo R Lastra , Marion Curtis , S Diane Yamada , Ruth Perets , Stephanie M McGregor , Jorge Andrade , Oliver Fiehn , Raymond E Moellering , Matthias Mann , Ernst Lengyel

Safety and efficacy of quavonlimab, a novel anti-CTLA-4 antibody (MK-1308), in combination with pembrolizumab in first-line advanced non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: R Perets , J Bar , D W Rasco , M-J Ahn , K Yoh , D-W Kim , A Nagrial , M Satouchi , D H Lee , D R Spigel , D Kotasek , M Gutierrez , J Niu , S Siddiqi , X Li , J Cyrus , A Chackerian , A Chain , R A Altura , B C Cho

DIO3, the thyroid hormone inactivating enzyme, promotes tumorigenesis and metabolic reprogramming in high grade serous ovarian cancer.

Cancer letters

Avec: Dotan Moskovich , Adi Alfandari , Yael Finkelshtein , Avivit Weisz , Aviva Katzav , Debora Kidron , Evgeny Edelstein , Daniel Veroslavski , Ruth Perets , Nissim Arbib , Yfat Kadan , Ami Fishman , Bernard Lerer , Martin Ellis , Osnat Ashur-Fabian

Mutated p53 in HGSC-From a Common Mutation to a Target for Therapy.

Cancers

Avec: Aya Saleh , Ruth Perets

A phase 1 study of intravenous mitazalimab, a CD40 agonistic monoclonal antibody, in patients with advanced solid tumors.

Investigational new drugs

Avec: Victor Moreno , Ruth Perets , Tamar Peretz-Yablonski , Nele Fourneau , Suzette Girgis , Yue Guo , Peter Hellemans , Raluca Verona , Natalia Pendás , Qi Xia , Ravit Geva , Emiliano Calvo

Phase II study to determine the anti-tumor activity and safety of simlukafusp alfa (FAP-IL2v) combined with atezolizumab in esophageal cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Hans Prenen , Sanjeev Deva , Bhumsuk Keam , Colin R Lindsay , Iwona Lugowska , James C Yang , Federico Longo , Maria de Miguel , Mariano Ponz-Sarvise , Myung-Ju Ahn , Mahmut Gumus , Stephane Champiat , Antoine Italiano , Sebastien Salas , Ruth Perets , Cagatay Arslan , Byoung C Cho , Stefan Evers , Christophe Boetsch , Daniel Marbach , David Dejardin , Nassim Sleiman , Caroline Ardeshir , Muriel Richard , Jehad Charo , Anton Kraxner , Nino Keshelava , Volker Teichgräber , Victor Moreno

Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers.

Cancers

Avec: Martha Dillon , Antonio Lopez , Edward Lin , Dominic Sales , Ron Perets , Pooja Jain

Réseau de co-auteurs

Ravit Geva 4 collaborations

Antoine Italiano 3 collaborations

Iwona Lugowska 3 collaborations

Myung-Ju Ahn 3 collaborations

Sylvie Rottey 2 collaborations

Reli Rachel Kakun 2 collaborations

Hans Prenen 2 collaborations

Mahmut Gumus 2 collaborations

Cagatay Arslan 2 collaborations

Colin R Lindsay 2 collaborations

Sanjeev Deva 2 collaborations

Daniel Marbach 2 collaborations

Christophe Boetsch 2 collaborations

David Dejardin 2 collaborations

Nassim Sleiman 2 collaborations

Stefan Evers 2 collaborations

Muriel Richard 2 collaborations

Caroline Ardeshir 2 collaborations

Jehad Charo 2 collaborations

Anton Kraxner 2 collaborations

Volker Teichgräber 2 collaborations

Nino Keshelava 2 collaborations

Drew Rasco 2 collaborations

Jiaxin Niu 2 collaborations

Corinne Maurice-Dror 2 collaborations

Shabana Siddiqi 2 collaborations

Rachel A Altura 2 collaborations

Ronnie Shapira-Frommer 2 collaborations

Victor Moreno 2 collaborations

Alberto A Gabizon 1 collaboration

Esther Tahover 1 collaboration

Talia Golan 1 collaboration

Yasmine Amitay 1 collaboration

Hilary Shmeeda 1 collaboration

Patricia Ohana 1 collaboration

Gerald S Falchook 1 collaboration

Marc Peeters 1 collaboration

Luc Y Dirix 1 collaboration

Radka Obermannova 1 collaboration

Jonathan E Cohen 1 collaboration

Ronnie Shapira Frommer 1 collaboration

Todd M Bauer 1 collaboration

Judy S Wang 1 collaboration

Richard D Carvajal 1 collaboration

Joshua Sabari 1 collaboration

Sonya Chapman 1 collaboration

Wei Zhang 1 collaboration

Boris Calderon 1 collaboration

Daniel A Peterson 1 collaboration

Zohar Melamed 1 collaboration

Loic Verlingue 1 collaboration

Eva Maria Guerra Alia 1 collaboration

Diego Tosi 1 collaboration

Vladimir Moiseyenko 1 collaboration

Álvaro Taus 1 collaboration

Ana Oaknin 1 collaboration

Irfan Cicin 1 collaboration

Sema Sezgin Goksu 1 collaboration

Alexey Smolin 1 collaboration

Susana Roselló-Keränen 1 collaboration

Christin Habigt 1 collaboration

Rafal Dziadziuszko 1 collaboration

Byoung Chul Cho 1 collaboration

Kiyotaka Yoh 1 collaboration

Adnan Nagrial 1 collaboration

David R Spigel 1 collaboration

Martin Gutierrez 1 collaboration

Dong-Wan Kim 1 collaboration

Dusan Kotasek 1 collaboration

Miyako Satouchi 1 collaboration

Dae Ho Lee 1 collaboration

Yixin Ren 1 collaboration

Jair Bar 1 collaboration

Solange Peters 1 collaboration

Geoffrey Shouse 1 collaboration

Marina C Garassino 1 collaboration

Jacob Sands 1 collaboration

Tanya Keenan 1 collaboration

Bin Zhao 1 collaboration

Jane Healy 1 collaboration

Eleni Maniati 1 collaboration

Chiara Berlato 1 collaboration

Ganga Gopinathan 1 collaboration

Owen Heath 1 collaboration

Panoraia Kotantaki 1 collaboration

Anissa Lakhani 1 collaboration

Jacqueline McDermott 1 collaboration

Colin Pegrum 1 collaboration

Robin M Delaine-Smith 1 collaboration

Oliver M T Pearce 1 collaboration

Priyanka Hirani 1 collaboration

Joash D Joy 1 collaboration

Ludmila Szabova 1 collaboration

Owen J Sansom 1 collaboration

Ronny Drapkin 1 collaboration

Peter Bailey 1 collaboration

Frances R Balkwill 1 collaboration

Juanita Lopez 1 collaboration

Sarah Danson 1 collaboration

Heikki Joensuu 1 collaboration

Avivit Peer 1 collaboration

Samuel J Harris 1 collaboration

Fabricio Souza 1 collaboration

Kaline M C Pereira 1 collaboration

Tarek Taha 1 collaboration

Ari Reiss 1 collaboration

Amnon Amit 1 collaboration

Lillian L Siu 1 collaboration

Ding Wang 1 collaboration

John Hilton 1 collaboration

Anson K Abraham 1 collaboration

Douglas C Wilson 1 collaboration

Julia F Markensohn 1 collaboration

Jared Lunceford 1 collaboration

Leah Suttner 1 collaboration

Basem Fares 1 collaboration

Liron Berger 1 collaboration

Einav Bangiev-Girsh 1 collaboration

Dima Ghannam-Shahbari 1 collaboration

Yuval Tabach 1 collaboration

Yaniv Zohar 1 collaboration

Eyal Gottlieb 1 collaboration

Toni K Choueiri 1 collaboration

Harriet Kluger 1 collaboration

Saby George 1 collaboration

Scott S Tykodi 1 collaboration

Timothy M Kuzel 1 collaboration

Suresh Nair 1 collaboration

Giuseppe Procopio 1 collaboration

Michael A Carducci 1 collaboration

Vincent Castonguay 1 collaboration

Edmund Folefac 1 collaboration

Chung-Han Lee 1 collaboration

Sebastien J Hotte 1 collaboration

Wilson H Miller 1 collaboration

Shruti Shally Saggi 1 collaboration

Chung-Wei Lee 1 collaboration

Heshani Desilva 1 collaboration

Prabhu Bhagavatheeswaran 1 collaboration

Robert J Motzer 1 collaboration

Bernard Escudier 1 collaboration

Hyun Cheol Chung 1 collaboration

Willeke Ros 1 collaboration

Jean-Pierre Delord 1 collaboration

Lyudmila Manzuk 1 collaboration

Sarina A Piha-Paul 1 collaboration

Lei Xu 1 collaboration

Susan Zeigenfuss 1 collaboration

Scott K Pruitt 1 collaboration

Alexandra Leary 1 collaboration

Mark A Eckert 1 collaboration

Fabian Coscia 1 collaboration

Agnieszka Chryplewicz 1 collaboration

Jae Won Chang 1 collaboration

Kyle M Hernandez 1 collaboration

Shawn Pan 1 collaboration

Samantha M Tienda 1 collaboration

Dominik A Nahotko 1 collaboration

Gang Li 1 collaboration

Ivana Blaženović 1 collaboration

Ricardo R Lastra 1 collaboration

Marion Curtis 1 collaboration

S Diane Yamada 1 collaboration

Stephanie M McGregor 1 collaboration

Jorge Andrade 1 collaboration

Oliver Fiehn 1 collaboration

Raymond E Moellering 1 collaboration

Matthias Mann 1 collaboration

Ernst Lengyel 1 collaboration

R Perets 1 collaboration

J Bar 1 collaboration

D W Rasco 1 collaboration

M-J Ahn 1 collaboration

K Yoh 1 collaboration

D-W Kim 1 collaboration

A Nagrial 1 collaboration

M Satouchi 1 collaboration

D H Lee 1 collaboration

D R Spigel 1 collaboration

D Kotasek 1 collaboration

M Gutierrez 1 collaboration

J Niu 1 collaboration

S Siddiqi 1 collaboration

X Li 1 collaboration

J Cyrus 1 collaboration

A Chackerian 1 collaboration

A Chain 1 collaboration

R A Altura 1 collaboration

B C Cho 1 collaboration

Dotan Moskovich 1 collaboration

Adi Alfandari 1 collaboration

Yael Finkelshtein 1 collaboration

Avivit Weisz 1 collaboration

Aviva Katzav 1 collaboration

Debora Kidron 1 collaboration

Evgeny Edelstein 1 collaboration

Daniel Veroslavski 1 collaboration

Nissim Arbib 1 collaboration

Yfat Kadan 1 collaboration

Ami Fishman 1 collaboration

Bernard Lerer 1 collaboration

Martin Ellis 1 collaboration

Osnat Ashur-Fabian 1 collaboration

Aya Saleh 1 collaboration

Tamar Peretz-Yablonski 1 collaboration

Nele Fourneau 1 collaboration

Suzette Girgis 1 collaboration

Yue Guo 1 collaboration

Peter Hellemans 1 collaboration

Raluca Verona 1 collaboration

Natalia Pendás 1 collaboration

Qi Xia 1 collaboration

Emiliano Calvo 1 collaboration

Bhumsuk Keam 1 collaboration

James C Yang 1 collaboration

Federico Longo 1 collaboration

Maria de Miguel 1 collaboration

Mariano Ponz-Sarvise 1 collaboration

Stephane Champiat 1 collaboration

Sebastien Salas 1 collaboration

Byoung C Cho 1 collaboration

Martha Dillon 1 collaboration

Antonio Lopez 1 collaboration

Edward Lin 1 collaboration

Dominic Sales 1 collaboration

Ron Perets 1 collaboration

Pooja Jain 1 collaboration