Sara Insausti

Affiliations

Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080, Bilbao, Spain.

Publications (10)

Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.

Nature communications

Avec: Pablo Carravilla , Jakub Chojnacki , Edurne Rujas , Sara Insausti , Eneko Largo , Dominic Waithe , Beatriz Apellaniz , Taylor Sicard , Jean-Philippe Julien , Christian Eggeling , José L Nieva

On the antimicrobial properties and endurance of eugenol and 2-phenylphenol functionalized sol-gel coatings.

Heliyon

Avec: Ana Suárez-Vega , Gemma Berriozabal , Juan Perez de Iriarte , Jaione Lorenzo , Noelia Álvarez , Santiago Dominguez-Meister , Sara Insausti , Edurne Rujas , Jose L Nieva , Marta Brizuela , Iñigo Braceras

Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Edurne Rujas , Hong Cui , Jonathan Burnie , Clare Burn Aschner , Tiantian Zhao , Sara Insausti , Krithika Muthuraman , Anthony Semesi , Jasper Ophel , Jose L Nieva , Michael S Seaman , Christina Guzzo , Bebhinn Treanor , Jean-Philippe Julien

Generation of a Nonbilayer Lipid Nanoenvironment after Epitope Binding Potentiates Neutralizing HIV-1 MPER Antibody.

ACS applied materials & interfaces

Avec: Sara Insausti , Ander Ramos-Caballero , Brian Wiley , Saul González-Resines , Johana Torralba , Anne Elizaga-Lara , Christine Shamblin , Akio Ojida , Jose M M Caaveiro , Michael B Zwick , Edurne Rujas , Carmen Domene , José L Nieva

Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.

iScience

Avec: Edurne Rujas , Daniel P Leaman , Sara Insausti , Pablo Carravilla , Miguel García-Porras , Eneko Largo , Izaskun Morillo , Rubén Sánchez-Eugenia , Lei Zhang , Hong Cui , Ibon Iloro , Félix Elortza , Jean-Philippe Julien , Christian Eggeling , Michael B Zwick , Jose M M Caaveiro , José L Nieva

Functional Delineation of a Protein-Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8.

International journal of molecular sciences

Avec: Sara Insausti , Miguel Garcia-Porras , Johana Torralba , Izaskun Morillo , Ander Ramos-Caballero , Igor de la Arada , Beatriz Apellaniz , Jose M M Caaveiro , Pablo Carravilla , Christian Eggeling , Edurne Rujas , Jose L Nieva

Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.

Communications biology

Avec: Johana Torralba , Igor de la Arada , Angélica Partida-Hanon , Edurne Rujas , Madalen Arribas , Sara Insausti , Claire Valotteau , Javier Valle , David Andreu , José M M Caaveiro , María Angeles Jiménez , Beatriz Apellániz , Lorena Redondo-Morata , José L Nieva

A two-step mechanism for the binding of the HIV-1 MPER epitope by the 10E8 antibody onto biosensor-supported lipid bilayers.

FEBS letters

Avec: Miguel García-Porras , Johana Torralba , Sara Insausti , Javier Valle , David Andreu , Beatriz Apellániz , José L Nieva

Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope.

ACS infectious diseases

Avec: Johana Torralba , Igor de la Arada , Pablo Carravilla , Sara Insausti , Edurne Rujas , Eneko Largo , Christian Eggeling , José L R Arrondo , Beatriz Apellániz , José L Nieva

Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments.

Cell reports

Avec: Edurne Rujas , Sara Insausti , Daniel P Leaman , Pablo Carravilla , Saul González-Resines , Valérie Monceaux , Rubén Sánchez-Eugenia , Miguel García-Porras , Ibon Iloro , Lei Zhang , Félix Elortza , Jean-Philippe Julien , Asier Saéz-Cirión , Michael B Zwick , Christian Eggeling , Akio Ojida , Carmen Domene , Jose M M Caaveiro , José L Nieva

Réseau de co-auteurs

Edurne Rujas 9 collaborations

José L Nieva 7 collaborations

Pablo Carravilla 5 collaborations

Christian Eggeling 5 collaborations

Johana Torralba 5 collaborations

Jean-Philippe Julien 4 collaborations

Jose M M Caaveiro 4 collaborations

Eneko Largo 3 collaborations

Jose L Nieva 3 collaborations

Michael B Zwick 3 collaborations

Miguel García-Porras 3 collaborations

Igor de la Arada 3 collaborations

Beatriz Apellániz 3 collaborations

Beatriz Apellaniz 2 collaborations

Hong Cui 2 collaborations

Ander Ramos-Caballero 2 collaborations

Saul González-Resines 2 collaborations

Akio Ojida 2 collaborations

Carmen Domene 2 collaborations

Daniel P Leaman 2 collaborations

Izaskun Morillo 2 collaborations

Rubén Sánchez-Eugenia 2 collaborations

Lei Zhang 2 collaborations

Ibon Iloro 2 collaborations

Félix Elortza 2 collaborations

Javier Valle 2 collaborations

David Andreu 2 collaborations

Jakub Chojnacki 1 collaboration

Dominic Waithe 1 collaboration

Taylor Sicard 1 collaboration

Ana Suárez-Vega 1 collaboration

Gemma Berriozabal 1 collaboration

Juan Perez de Iriarte 1 collaboration

Jaione Lorenzo 1 collaboration

Noelia Álvarez 1 collaboration

Santiago Dominguez-Meister 1 collaboration

Marta Brizuela 1 collaboration

Iñigo Braceras 1 collaboration

Jonathan Burnie 1 collaboration

Clare Burn Aschner 1 collaboration

Tiantian Zhao 1 collaboration

Krithika Muthuraman 1 collaboration

Anthony Semesi 1 collaboration

Jasper Ophel 1 collaboration

Michael S Seaman 1 collaboration

Christina Guzzo 1 collaboration

Bebhinn Treanor 1 collaboration

Brian Wiley 1 collaboration

Anne Elizaga-Lara 1 collaboration

Christine Shamblin 1 collaboration

Miguel Garcia-Porras 1 collaboration

Angélica Partida-Hanon 1 collaboration

Madalen Arribas 1 collaboration

Claire Valotteau 1 collaboration

José M M Caaveiro 1 collaboration

María Angeles Jiménez 1 collaboration

Lorena Redondo-Morata 1 collaboration

José L R Arrondo 1 collaboration

Valérie Monceaux 1 collaboration

Asier Saéz-Cirión 1 collaboration