Sara Rattik

Affiliations

Center for Systems Biology and Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Publications (13)

Liver X receptors are required for thymic resilience and T cell output.

The Journal of experimental medicine

Avec: Christopher T Chan , Ashley M Fenn , Nina K Harder , John E Mindur , Cameron S McAlpine , Jyoti Patel , Colin Valet , Sara Rattik , Yoshiko Iwamoto , Shun He , Atsushi Anzai , Florian Kahles , Wolfram C Poller , Henrike Janssen , Lai Ping Wong , Carlos Fernandez-Hernando , David R Koolbergen , Anja M van der Laan , Laurent Yvan-Charvet , Ruslan I Sadreyev , Matthias Nahrendorf , Marit Westerterp , Alan R Tall , Jan-Ake Gustafsson , Filip K Swirski

Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.

Annals of the rheumatic diseases

Avec: Caitríona Grönberg , Sara Rattik , Cuong Tran-Manh , Xiang Zhou , Aleix Rius Rigau , Yi-Nan Li , Andrea-Hermina Györfi , Nicholas Dickel , Meik Kunz , Alexander Kreuter , Emil-Alexandru Matei , Honglin Zhu , Petter Skoog , David Liberg , Jörg Hw Distler , Thuong Trinh-Minh

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.

Nature

Avec: Shun He , Florian Kahles , Sara Rattik , Manfred Nairz , Cameron S McAlpine , Atsushi Anzai , Daniel Selgrade , Ashley M Fenn , Christopher T Chan , John E Mindur , Colin Valet , Wolfram C Poller , Lennard Halle , Noemi Rotllan , Yoshiko Iwamoto , Gregory R Wojtkiewicz , Ralph Weissleder , Peter Libby , Carlos Fernández-Hernando , Daniel J Drucker , Matthias Nahrendorf , Filip K Swirski

Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.

Cell reports

Avec: James K Fields , Elin Jaensson Gyllenbäck , Marek Bogacz , Juliet Obi , Gabriel Svensson Birkedal , Kjell Sjöström , Kino Maravillas , Caitríona Grönberg , Sara Rattik , Kyle Kihn , Maria Flowers , Ally K Smith , Nils Hansen , Thoas Fioretos , Chau Huyhn , David Liberg , Daniel Deredge , Eric J Sundberg

Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.

Scientific reports

Avec: Daniel Engelbertsen , Anu Autio , Robin A F Verwilligen , Marie A C Depuydt , Gail Newton , Sara Rattik , Erik Levinsohn , Gurpanna Saggu , Petr Jarolim , Huan Wang , Francisco Velazquez , Andrew H Lichtman , Francis W Luscinskas

Elevated circulating effector memory T cells but similar levels of regulatory T cells in patients with type 2 diabetes mellitus and cardiovascular disease.

Diabetes & vascular disease research

Avec: Sara Rattik , Daniel Engelbertsen , Maria Wigren , Irena Ljungcrantz , Gerd Östling , Margaretha Persson , Gunilla Nordin Fredrikson , Eva Bengtsson , Jan Nilsson , Harry Björkbacka

Immune responses against oxidized LDL as possible targets for prevention of atherosclerosis in systemic lupus erythematosus.

Vascular pharmacology

Avec: Ingrid Yao Mattisson , Sara Rattik , Harry Björkbacka , Irena Ljungcrantz , Manuela Terrinoni , Michael Lebens , Jan Holmgren , Gunilla Nordin Fredrikson , Birgitta Gullstrand , Anders A Bengtsson , Jan Nilsson , Maria Wigren

IL-2Rβγ signalling in lymphocytes promotes systemic inflammation and reduces plasma cholesterol in atherosclerotic mice.

Atherosclerosis

Avec: Megan Mulholland , Gabriel Jakobsson , Yu Lei , Lena Sundius , Irena Ljungcrantz , Sara Rattik , Uwe J F Tietge , Daniel Engelbertsen

Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic hypercholesterolemia.

NPJ aging and mechanisms of disease

Avec: Nicholas Don-Doncow , Lotte Vanherle , Frank Matthes , Sine Kragh Petersen , Hana Matuskova , Sara Rattik , Anetta Härtlova , Anja Meissner

Sleep modulates haematopoiesis and protects against atherosclerosis.

Nature

Avec: Cameron S McAlpine , Máté G Kiss , Sara Rattik , Shun He , Anne Vassalli , Colin Valet , Atsushi Anzai , Christopher T Chan , John E Mindur , Florian Kahles , Wolfram C Poller , Vanessa Frodermann , Ashley M Fenn , Annemijn F Gregory , Lennard Halle , Yoshiko Iwamoto , Friedrich F Hoyer , Christoph J Binder , Peter Libby , Mehdi Tafti , Thomas E Scammell , Matthias Nahrendorf , Filip K Swirski

Lack of Ability to Present Antigens on Major Histocompatibility Complex Class II Molecules Aggravates Atherosclerosis in ApoE

Circulation

Avec: Maria Wigren , Sara Rattik , Ingrid Yao Mattisson , Lukas Tomas , Caitriona Grönberg , Ingrid Söderberg , Ragnar Alm , Lena Sundius , Irena Ljungcrantz , Harry Björkbacka , Gunilla Nordin Fredrikson , Jan Nilsson

Self-reactive CD4

The Journal of experimental medicine

Avec: Atsushi Anzai , John E Mindur , Lennard Halle , Soichi Sano , Jennifer L Choi , Shun He , Cameron S McAlpine , Christopher T Chan , Florian Kahles , Colin Valet , Ashley M Fenn , Manfred Nairz , Sara Rattik , Yoshiko Iwamoto , DeLisa Fairweather , Kenneth Walsh , Peter Libby , Matthias Nahrendorf , Filip K Swirski

Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.

Cardiovascular research

Avec: Megan Mulholland , Marie A C Depuydt , Gabriel Jakobsson , Irena Ljungcrantz , Andrietta Grentzmann , Fong To , Eva Bengtsson , Elin Jaensson Gyllenbäck , Caitríona Grönberg , Sara Rattik , David Liberg , Alexandru Schiopu , Harry Björkbacka , Johan Kuiper , Ilze Bot , Bram Slütter , Daniel Engelbertsen

Réseau de co-auteurs

Irena Ljungcrantz 5 collaborations

Christopher T Chan 4 collaborations

Ashley M Fenn 4 collaborations

John E Mindur 4 collaborations

Cameron S McAlpine 4 collaborations

Colin Valet 4 collaborations

Yoshiko Iwamoto 4 collaborations

Shun He 4 collaborations

Atsushi Anzai 4 collaborations

Florian Kahles 4 collaborations

Matthias Nahrendorf 4 collaborations

Filip K Swirski 4 collaborations

Daniel Engelbertsen 4 collaborations

Harry Björkbacka 4 collaborations

Wolfram C Poller 3 collaborations

Caitríona Grönberg 3 collaborations

David Liberg 3 collaborations

Lennard Halle 3 collaborations

Peter Libby 3 collaborations

Maria Wigren 3 collaborations

Gunilla Nordin Fredrikson 3 collaborations

Jan Nilsson 3 collaborations

Manfred Nairz 2 collaborations

Elin Jaensson Gyllenbäck 2 collaborations

Marie A C Depuydt 2 collaborations

Eva Bengtsson 2 collaborations

Ingrid Yao Mattisson 2 collaborations

Megan Mulholland 2 collaborations

Gabriel Jakobsson 2 collaborations

Lena Sundius 2 collaborations

Nina K Harder 1 collaboration

Jyoti Patel 1 collaboration

Henrike Janssen 1 collaboration

Lai Ping Wong 1 collaboration

Carlos Fernandez-Hernando 1 collaboration

David R Koolbergen 1 collaboration

Anja M van der Laan 1 collaboration

Laurent Yvan-Charvet 1 collaboration

Ruslan I Sadreyev 1 collaboration

Marit Westerterp 1 collaboration

Alan R Tall 1 collaboration

Jan-Ake Gustafsson 1 collaboration

Cuong Tran-Manh 1 collaboration

Xiang Zhou 1 collaboration

Aleix Rius Rigau 1 collaboration

Yi-Nan Li 1 collaboration

Andrea-Hermina Györfi 1 collaboration

Nicholas Dickel 1 collaboration

Meik Kunz 1 collaboration

Alexander Kreuter 1 collaboration

Emil-Alexandru Matei 1 collaboration

Honglin Zhu 1 collaboration

Petter Skoog 1 collaboration

Jörg Hw Distler 1 collaboration

Thuong Trinh-Minh 1 collaboration

Daniel Selgrade 1 collaboration

Noemi Rotllan 1 collaboration

Gregory R Wojtkiewicz 1 collaboration

Ralph Weissleder 1 collaboration

Carlos Fernández-Hernando 1 collaboration

Daniel J Drucker 1 collaboration

James K Fields 1 collaboration

Marek Bogacz 1 collaboration

Juliet Obi 1 collaboration

Gabriel Svensson Birkedal 1 collaboration

Kjell Sjöström 1 collaboration

Kino Maravillas 1 collaboration

Kyle Kihn 1 collaboration

Maria Flowers 1 collaboration

Ally K Smith 1 collaboration

Nils Hansen 1 collaboration

Thoas Fioretos 1 collaboration

Chau Huyhn 1 collaboration

Daniel Deredge 1 collaboration

Eric J Sundberg 1 collaboration

Anu Autio 1 collaboration

Robin A F Verwilligen 1 collaboration

Gail Newton 1 collaboration

Erik Levinsohn 1 collaboration

Gurpanna Saggu 1 collaboration

Petr Jarolim 1 collaboration

Huan Wang 1 collaboration

Francisco Velazquez 1 collaboration

Andrew H Lichtman 1 collaboration

Francis W Luscinskas 1 collaboration

Gerd Östling 1 collaboration

Margaretha Persson 1 collaboration

Manuela Terrinoni 1 collaboration

Michael Lebens 1 collaboration

Jan Holmgren 1 collaboration

Birgitta Gullstrand 1 collaboration

Anders A Bengtsson 1 collaboration

Yu Lei 1 collaboration

Uwe J F Tietge 1 collaboration

Nicholas Don-Doncow 1 collaboration

Lotte Vanherle 1 collaboration

Frank Matthes 1 collaboration

Sine Kragh Petersen 1 collaboration

Hana Matuskova 1 collaboration

Anetta Härtlova 1 collaboration

Anja Meissner 1 collaboration

Máté G Kiss 1 collaboration

Anne Vassalli 1 collaboration

Vanessa Frodermann 1 collaboration

Annemijn F Gregory 1 collaboration

Friedrich F Hoyer 1 collaboration

Christoph J Binder 1 collaboration

Mehdi Tafti 1 collaboration

Thomas E Scammell 1 collaboration

Lukas Tomas 1 collaboration

Caitriona Grönberg 1 collaboration

Ingrid Söderberg 1 collaboration

Ragnar Alm 1 collaboration

Soichi Sano 1 collaboration

Jennifer L Choi 1 collaboration

DeLisa Fairweather 1 collaboration

Kenneth Walsh 1 collaboration

Andrietta Grentzmann 1 collaboration

Fong To 1 collaboration

Alexandru Schiopu 1 collaboration

Johan Kuiper 1 collaboration

Ilze Bot 1 collaboration

Bram Slütter 1 collaboration