Shiv Ram Krishn

Affiliations

Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Publications (15)

Methods for extracellular vesicle isolation from cancer cells.

Cancer drug resistance (Alhambra, Calif.)

Avec: Israa Salem , Nicole M Naranjo , Amrita Singh , Rachel DeRita , Shiv Ram Krishn , Luca S Sirman , Fabio Quaglia , Alexander Duffy , Nicholas Bowler , Aejaz Sayeed , Lucia R Languino

Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model.

Biology open

Avec: Kavita Mallya , Dhanya Haridas , Parthasarathy Seshacharyulu , Ramesh Pothuraju , Wade M Junker , Shiv Ram Krishn , Sakthivel Muniyan , Raghupathy Vengoji , Surinder K Batra , Satyanarayana Rachagani

Mechanistic and Functional Shades of Mucins and Associated Glycans in Colon Cancer.

Cancers

Avec: Ramesh Pothuraju , Shiv Ram Krishn , Shailendra K Gautam , Priya Pai , Koelina Ganguly , Sanjib Chaudhary , Satyanarayana Rachagani , Sukhwinder Kaur , Surinder K Batra

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth.

The Journal of biological chemistry

Avec: Ekta Agarwal , Brian J Altman , Jae Ho Seo , Jagadish C Ghosh , Andrew V Kossenkov , Hsin-Yao Tang , Shiv Ram Krishn , Lucia R Languino , Dmitry I Gabrilovich , David W Speicher , Chi V Dang , Dario C Altieri

Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells.

Journal of extracellular vesicles

Avec: Fabio Quaglia , Shiv Ram Krishn , George G Daaboul , Srawasti Sarker , Raffaella Pippa , Josep Domingo-Domenech , Gaurav Kumar , Paolo Fortina , Peter McCue , William K Kelly , Himisha Beltran , Qin Liu , Lucia R Languino

The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer.

Scientific reports

Avec: Fabio Quaglia , Shiv Ram Krishn , Khalid Sossey-Alaoui , Priyanka Shailendra Rana , Elzbieta Pluskota , Pyung Hun Park , Christopher D Shields , Stephen Lin , Peter McCue , Andrew V Kossenkov , Yanqing Wang , David W Goodrich , Sheng-Yu Ku , Himisha Beltran , William K Kelly , Eva Corey , Maja Klose , Christine Bandtlow , Qin Liu , Dario C Altieri , Edward F Plow , Lucia R Languino

Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment.

Developmental cell

Avec: Irene Bertolini , Jagadish C Ghosh , Andrew V Kossenkov , Sudheer Mulugu , Shiv Ram Krishn , Valentina Vaira , Jun Qin , Edward F Plow , Lucia R Languino , Dario C Altieri

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis.

Journal of extracellular vesicles

Avec: Shiv Ram Krishn , Israa Salem , Fabio Quaglia , Nicole M Naranjo , Ekta Agarwal , Qin Liu , Srawasti Sarker , Jessica Kopenhaver , Peter A McCue , Paul H Weinreb , Shelia M Violette , Dario C Altieri , Lucia R Languino

Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness.

Cancer research

Avec: Koelina Ganguly , Shiv Ram Krishn , Satyanarayana Rachagani , Rahat Jahan , Ashu Shah , Palanisamy Nallasamy , Sanchita Rauth , Pranita Atri , Jesse L Cox , Ramesh Pothuraju , Lynette M Smith , Sudhua Ayala , Christopher Evans , Moorthy P Ponnusamy , Sushil Kumar , Sukhwinder Kaur , Surinder K Batra

BCA101 Is a Tumor-Targeted Bifunctional Fusion Antibody That Simultaneously Inhibits EGFR and TGFβ Signaling to Durably Suppress Tumor Growth.

Cancer research

Avec: Srinivas Reddy Boreddy , Reshmi Nair , Prashant Kumar Pandey , Anshu Kuriakose , Shivakumar Bhadravathi Marigowda , Chaitali Dey , Arindam Banerjee , Hanumant Kulkarni , Milind Sagar , Shiv Ram Krishn , Shruthi Rao , Madhukara Ar , Vinita Tiwari , Bhavna Alke , Prashantha Kumar Mv , Meena Shri , Chaitrali Dhamne , Sonal Patel , Pinky Sharma , Sankar Periyasamy , Jaya Bhatnagar , Moni Abraham Kuriakose , Ram Bhupal Reddy , Amritha Suresh , Suma Sreenivas , Nagaraja Govindappa , Praveen Reddy Moole , Usha Bughani , Seng-Lai Tan , Pradip Nair

Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression.

PloS one

Avec: Fabio Quaglia , Shiv Ram Krishn , Yanqing Wang , David W Goodrich , Peter McCue , Andrew V Kossenkov , Amy C Mandigo , Karen E Knudsen , Paul H Weinreb , Eva Corey , William K Kelly , Lucia R Languino

Prostate cancer sheds the αvβ3 integrin in vivo through exosomes.

Matrix biology : journal of the International Society for Matrix Biology

Avec: Shiv Ram Krishn , Amrita Singh , Nicholas Bowler , Alexander N Duffy , Andrea Friedman , Carmine Fedele , Senem Kurtoglu , Sushil K Tripathi , Kerith Wang , Adam Hawkins , Aejaz Sayeed , Chirayu P Goswami , Madhukar L Thakur , Renato V Iozzo , Stephen C Peiper , William K Kelly , Lucia R Languino

Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth.

iScience

Avec: Rachel M DeRita , Aejaz Sayeed , Vaughn Garcia , Shiv Ram Krishn , Christopher D Shields , Srawasti Sarker , Andrea Friedman , Peter McCue , Sudheer Kumar Molugu , Ulrich Rodeck , Adam P Dicker , Lucia R Languino

Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance.

Molecular cancer

Avec: Ramesh Pothuraju , Satyanarayana Rachagani , Shiv Ram Krishn , Sanjib Chaudhary , Rama Krishna Nimmakayala , Jawed A Siddiqui , Koelina Ganguly , Imayavaramban Lakshmanan , Jesse L Cox , Kavita Mallya , Sukhwinder Kaur , Surinder K Batra

Small extracellular vesicle-mediated

Cancer biology & therapy

Avec: Shiv Ram Krishn , Vaughn Garcia , Nicole M Naranjo , Fabio Quaglia , Christopher D Shields , Maisha A Harris , Andrew V Kossenkov , Qin Liu , Eva Corey , Dario C Altieri , Lucia R Languino

Réseau de co-auteurs

Lucia R Languino 10 collaborations

Fabio Quaglia 6 collaborations

Andrew V Kossenkov 5 collaborations

Dario C Altieri 5 collaborations

Ramesh Pothuraju 4 collaborations

Surinder K Batra 4 collaborations

Satyanarayana Rachagani 4 collaborations

Peter McCue 4 collaborations

William K Kelly 4 collaborations

Qin Liu 4 collaborations

Nicole M Naranjo 3 collaborations

Aejaz Sayeed 3 collaborations

Koelina Ganguly 3 collaborations

Sukhwinder Kaur 3 collaborations

Srawasti Sarker 3 collaborations

Christopher D Shields 3 collaborations

Eva Corey 3 collaborations

Israa Salem 2 collaborations

Amrita Singh 2 collaborations

Nicholas Bowler 2 collaborations

Kavita Mallya 2 collaborations

Sanjib Chaudhary 2 collaborations

Ekta Agarwal 2 collaborations

Jagadish C Ghosh 2 collaborations

Himisha Beltran 2 collaborations

Yanqing Wang 2 collaborations

David W Goodrich 2 collaborations

Edward F Plow 2 collaborations

Paul H Weinreb 2 collaborations

Jesse L Cox 2 collaborations

Andrea Friedman 2 collaborations

Vaughn Garcia 2 collaborations

Rachel DeRita 1 collaboration

Luca S Sirman 1 collaboration

Alexander Duffy 1 collaboration

Dhanya Haridas 1 collaboration

Parthasarathy Seshacharyulu 1 collaboration

Wade M Junker 1 collaboration

Sakthivel Muniyan 1 collaboration

Raghupathy Vengoji 1 collaboration

Shailendra K Gautam 1 collaboration

Priya Pai 1 collaboration

Brian J Altman 1 collaboration

Jae Ho Seo 1 collaboration

Hsin-Yao Tang 1 collaboration

Dmitry I Gabrilovich 1 collaboration

David W Speicher 1 collaboration

Chi V Dang 1 collaboration

George G Daaboul 1 collaboration

Raffaella Pippa 1 collaboration

Josep Domingo-Domenech 1 collaboration

Gaurav Kumar 1 collaboration

Paolo Fortina 1 collaboration

Khalid Sossey-Alaoui 1 collaboration

Priyanka Shailendra Rana 1 collaboration

Elzbieta Pluskota 1 collaboration

Pyung Hun Park 1 collaboration

Stephen Lin 1 collaboration

Sheng-Yu Ku 1 collaboration

Maja Klose 1 collaboration

Christine Bandtlow 1 collaboration

Irene Bertolini 1 collaboration

Sudheer Mulugu 1 collaboration

Valentina Vaira 1 collaboration

Jun Qin 1 collaboration

Jessica Kopenhaver 1 collaboration

Peter A McCue 1 collaboration

Shelia M Violette 1 collaboration

Rahat Jahan 1 collaboration

Ashu Shah 1 collaboration

Palanisamy Nallasamy 1 collaboration

Sanchita Rauth 1 collaboration

Pranita Atri 1 collaboration

Lynette M Smith 1 collaboration

Sudhua Ayala 1 collaboration

Christopher Evans 1 collaboration

Moorthy P Ponnusamy 1 collaboration

Sushil Kumar 1 collaboration

Srinivas Reddy Boreddy 1 collaboration

Reshmi Nair 1 collaboration

Prashant Kumar Pandey 1 collaboration

Anshu Kuriakose 1 collaboration

Shivakumar Bhadravathi Marigowda 1 collaboration

Chaitali Dey 1 collaboration

Arindam Banerjee 1 collaboration

Hanumant Kulkarni 1 collaboration

Milind Sagar 1 collaboration

Shruthi Rao 1 collaboration

Madhukara Ar 1 collaboration

Vinita Tiwari 1 collaboration

Bhavna Alke 1 collaboration

Prashantha Kumar Mv 1 collaboration

Meena Shri 1 collaboration

Chaitrali Dhamne 1 collaboration

Sonal Patel 1 collaboration

Pinky Sharma 1 collaboration

Sankar Periyasamy 1 collaboration

Jaya Bhatnagar 1 collaboration

Moni Abraham Kuriakose 1 collaboration

Ram Bhupal Reddy 1 collaboration

Amritha Suresh 1 collaboration

Suma Sreenivas 1 collaboration

Nagaraja Govindappa 1 collaboration

Praveen Reddy Moole 1 collaboration

Usha Bughani 1 collaboration

Seng-Lai Tan 1 collaboration

Pradip Nair 1 collaboration

Amy C Mandigo 1 collaboration

Karen E Knudsen 1 collaboration

Alexander N Duffy 1 collaboration

Carmine Fedele 1 collaboration

Senem Kurtoglu 1 collaboration

Sushil K Tripathi 1 collaboration

Kerith Wang 1 collaboration

Adam Hawkins 1 collaboration

Chirayu P Goswami 1 collaboration

Madhukar L Thakur 1 collaboration

Renato V Iozzo 1 collaboration

Stephen C Peiper 1 collaboration

Rachel M DeRita 1 collaboration

Sudheer Kumar Molugu 1 collaboration

Ulrich Rodeck 1 collaboration

Adam P Dicker 1 collaboration

Rama Krishna Nimmakayala 1 collaboration

Jawed A Siddiqui 1 collaboration

Imayavaramban Lakshmanan 1 collaboration

Maisha A Harris 1 collaboration