Simone Perazzolo

Affiliations

Department of Pharmaceutics, University of Washington, Seattle, WA, 98195, USA. Electronic address: perazs@uw.edu.

Publications (13)

Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture.

Journal of pharmaceutical sciences

Avec: Simone Perazzolo , Laura M Shireman , Danny D Shen , Rodney J Y Ho

Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity.

International journal of obesity (2005)

Avec: Birgit Hirschmugl , Simone Perazzolo , Bram G Sengers , Rohan M Lewis , Michael Gruber , Gernot Desoye , Christian Wadsack

Novel Long-Acting Drug Combination Nanoparticles Composed of Gemcitabine and Paclitaxel Enhance Localization of Both Drugs in Metastatic Breast Cancer Nodules.

Pharmaceutical research

Avec: Jesse Yu , Qingxin Mu , Simone Perazzolo , James I Griffin , Linxi Zhu , Lisa A McConnachie , Danny D Shen , Rodney Jy Ho

Physiologically based Pharmacokinetic Model Validated to Enable Predictions of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products.

Journal of pharmaceutical sciences

Avec: Simone Perazzolo , Danny D Shen , Ariel M Scott , Rodney Jy Ho

SAAM II: A general mathematical modeling rapid prototyping environment.

CPT: pharmacometrics & systems pharmacology

Avec: Simone Perazzolo

Elevations in plasma glucagon are associated with reduced insulin clearance after ingestion of a mixed-macronutrient meal in people with and without type 2 diabetes.

Diabetologia

Avec: Kieran Smith , Guy S Taylor , Wouter Peeters , Mark Walker , Simone Perazzolo , Naeimeh Atabaki-Pasdar , Kelly A Bowden Davies , Fredrik Karpe , Leanne Hodson , Emma J Stevenson , Daniel J West

Bictegravir Plus Tenofovir Alafenamide Nanoformulation as a Long-Acting Pre-Exposure Prophylaxis Regimen: Application of Modeling to Design Non-Human Primate Pharmacokinetic Experiments.

Frontiers in pharmacology

Avec: Simone Perazzolo , Subhra Mandal , Pavan K Prathipati , Christopher J Destache

Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 2: Model for the Drug-combination Nanoparticles.

Journal of pharmaceutical sciences

Avec: Simone Perazzolo , Danny D Shen , Rodney J Y Ho

A novel formulation enabled transformation of 3-HIV drugs tenofovir-lamivudine-dolutegravir from short-acting to long-acting all-in-one injectable.

AIDS (London, England)

Avec: Simone Perazzolo , Zachary R Stephen , Masa Eguchi , Xiaolin Xu , Rachele Delle Fratte , Ann C Collier , Ann J Melvin , Rodney J Y Ho

Integration of Computational and Experimental Approaches to Elucidate Mechanisms of First-Pass Lymphatic Drug Sequestration and Long-Acting Pharmacokinetics of the Injectable Triple-HIV Drug Combination TLC-ART 101.

Journal of pharmaceutical sciences

Avec: Simone Perazzolo , Laura M Shireman , Lisa A McConnachie , Josefin Koehn , Loren Kinman , Wonsok Lee , Sarah Lane , Ann C Collier , Danny D Shen , Rodney J Y Ho

In vivo kinetic study of materno-fetal fatty acid transfer in obese and normal weight pregnant women.

The Journal of physiology

Avec: Antonio Gázquez , María T Prieto-Sánchez , José E Blanco-Carnero , Dewi van Harskamp , Simone Perazzolo , J Efraim Oosterink , Hans Demmelmair , Henk Schierbeek , Bram G Sengers , Rohan M Lewis , Johannes B van Goudoever , Berthold Koletzko , Elvira Larqué

Systems and Clinical Pharmacology of COVID-19 Therapeutic Candidates: A Clinical and Translational Medicine Perspective.

Journal of pharmaceutical sciences

Avec: Simone Perazzolo , Linxi Zhu , Weixian Lin , Alexander Nguyen , Rodney J Y Ho

Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques.

Frontiers in immunology

Avec: Sharat Srinivasula , Paula Degrange , Simone Perazzolo , Andrew Bonvillain , Amanda Tobery , Jacob Kaplan , Hyukjin Jang , Refika Turnier , Michael Davies , Mackenzie Cottrell , Rodney J Y Ho , Michele Di Mascio

Réseau de co-auteurs

Rodney J Y Ho 6 collaborations

Danny D Shen 5 collaborations

Laura M Shireman 2 collaborations

Bram G Sengers 2 collaborations

Rohan M Lewis 2 collaborations

Linxi Zhu 2 collaborations

Lisa A McConnachie 2 collaborations

Rodney Jy Ho 2 collaborations

Ann C Collier 2 collaborations

Birgit Hirschmugl 1 collaboration

Michael Gruber 1 collaboration

Gernot Desoye 1 collaboration

Christian Wadsack 1 collaboration

Jesse Yu 1 collaboration

Qingxin Mu 1 collaboration

James I Griffin 1 collaboration

Ariel M Scott 1 collaboration

Kieran Smith 1 collaboration

Guy S Taylor 1 collaboration

Wouter Peeters 1 collaboration

Mark Walker 1 collaboration

Naeimeh Atabaki-Pasdar 1 collaboration

Kelly A Bowden Davies 1 collaboration

Fredrik Karpe 1 collaboration

Leanne Hodson 1 collaboration

Emma J Stevenson 1 collaboration

Daniel J West 1 collaboration

Subhra Mandal 1 collaboration

Pavan K Prathipati 1 collaboration

Christopher J Destache 1 collaboration

Zachary R Stephen 1 collaboration

Masa Eguchi 1 collaboration

Xiaolin Xu 1 collaboration

Rachele Delle Fratte 1 collaboration

Ann J Melvin 1 collaboration

Josefin Koehn 1 collaboration

Loren Kinman 1 collaboration

Wonsok Lee 1 collaboration

Sarah Lane 1 collaboration

Antonio Gázquez 1 collaboration

María T Prieto-Sánchez 1 collaboration

José E Blanco-Carnero 1 collaboration

Dewi van Harskamp 1 collaboration

J Efraim Oosterink 1 collaboration

Hans Demmelmair 1 collaboration

Henk Schierbeek 1 collaboration

Johannes B van Goudoever 1 collaboration

Berthold Koletzko 1 collaboration

Elvira Larqué 1 collaboration

Weixian Lin 1 collaboration

Alexander Nguyen 1 collaboration

Sharat Srinivasula 1 collaboration

Paula Degrange 1 collaboration

Andrew Bonvillain 1 collaboration

Amanda Tobery 1 collaboration

Jacob Kaplan 1 collaboration

Hyukjin Jang 1 collaboration

Refika Turnier 1 collaboration

Michael Davies 1 collaboration

Mackenzie Cottrell 1 collaboration

Michele Di Mascio 1 collaboration