Uwe Liebchen

Affiliations

Department of Anesthesiology, University Hospital, LMU Munich, Germany.

Publications (43)

Trough concentrations of meropenem and piperacillin during slow extended dialysis in critically ill patients with intermittent and continuous infusion: A prospective observational study.

Journal of critical care

Avec: Uwe Liebchen , Michael Paal , Veronika Bucher , Michael Vogeser , Michael Irlbeck , Ines Schroeder , Michael Zoller , Christina Scharf

Combination of Pharmacokinetic and Pathogen Susceptibility Information To Optimize Meropenem Treatment of Gram-Negative Infections in Critically Ill Patients.

Antimicrobial agents and chemotherapy

Avec: Uwe Liebchen , Ferdinand Weinelt , Christina Scharf , Ines Schroeder , Michael Paal , Michael Zoller , Charlotte Kloft , Jette Jung , Robin Michelet

Does the cytokine adsorber CytoSorb

Annals of intensive care

Avec: Christina Scharf , Ferdinand Weinelt , Ines Schroeder , Michael Paal , Michael Weigand , Michael Zoller , Michael Irlbeck , Charlotte Kloft , Josef Briegel , Uwe Liebchen

Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain.

Antimicrobial agents and chemotherapy

Avec: Zhendong Chen , Max Taubert , Chunli Chen , Charalambos Dokos , Uwe Fuhr , Thomas Weig , Michael Zoller , Suzette Heck , Konstantinos Dimitriadis , Nicole Terpolilli , Christina Kinast , Christina Scharf , Constantin Lier , Christoph Dorn , Uwe Liebchen

Systematic Evaluation of Pharmacokinetic Models for Model-Informed Precision Dosing of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy.

Antimicrobial agents and chemotherapy

Avec: Lea Marie Schatz , Alexander Brinkmann , Anka Röhr , Otto Frey , Sebastian Greppmair , Ferdinand Weinelt , Michael Zoller , Christina Scharf , Georg Hempel , Uwe Liebchen

Software- and TDM-Guided Dosing of Meropenem Promises High Rates of Target Attainment in Critically Ill Patients.

Antibiotics (Basel, Switzerland)

Avec: Ute Chiriac , Daniel Richter , Otto R Frey , Anka C Röhr , Sophia Helbig , Stefan Hagel , Uwe Liebchen , Markus A Weigand , Alexander Brinkmann

Pharmacokinetics of immunosuppressive agents during hemoperfusion in a sheep model.

Frontiers in medicine

Avec: Bettina Leber , Uwe Liebchen , Lisa Rohrhofer , Jennifer Weber , Teresa Klaus , Joerg Scheier , Robert Sucher , Philipp Stiegler

Can the cytokine adsorber CytoSorb

Annals of intensive care

Avec: Christina Scharf , Ines Schroeder , Michael Paal , Martin Winkels , Michael Irlbeck , Michael Zoller , Uwe Liebchen

The effect of cytosorb® application on kidney recovery in critically ill patients with severe rhabdomyolysis: a propensity score matching analysis.

Renal failure

Avec: Caroline Gräfe , Uwe Liebchen , Antonia Greimel , Nils Maciuga , Mathias Bruegel , Michael Irlbeck , Lorenz Weidhase , Michael Zoller , Michael Paal , Christina Scharf

Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients.

Pharmaceutics

Avec: Hannah Kipka , Roland Tomasi , Max Hübner , Uwe Liebchen , Christian Hagl , Klaus T Wanner , Hanna Mannell , Georg Höfner

Serum linezolid concentrations are reduced in critically ill patients with pulmonary infections: A prospective observational study.

Journal of critical care

Avec: Michael Zoller , Michael Paal , Antonia Greimel , Simon Kallee , Michael Vogeser , Michael Irlbeck , Ines Schroeder , Uwe Liebchen , Christina Scharf

Can linezolid be validly measured in endotracheal aspiration in critically ill patients? A proof-of-concept trial.

Intensive care medicine experimental

Avec: Diana Rebholz , Uwe Liebchen , Michael Paal , Michael Vogeser , Johannes Starp , Caroline Gräfe , Clara I Brozat , Felix L Happich , Katharina Habler , Christina Scharf

Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass.

Frontiers in cardiovascular medicine

Avec: Hannah Kipka , Uwe Liebchen , Max Hübner , Georg Höfner , Otto Frey , Klaus T Wanner , Erich Kilger , Christian Hagl , Roland Tomasi , Hanna Mannell

Extracorporeal Elimination of Pro- and Anti-inflammatory Modulators by the Cytokine Adsorber CytoSorb

Infectious diseases and therapy

Avec: Helen Graf , Caroline Gräfe , Mathias Bruegel , Felix L Happich , Vassilissa Wustrow , Aljoscha Wegener , Wolfgang Wilfert , Michael Zoller , Uwe Liebchen , Michael Paal , Christina Scharf

Digestive enzymes of fungal origin as a relevant cause of false positive Aspergillus antigen testing in intensive care unit patients.

Infection

Avec: Ines Schroeder , Karl Dichtl , Uwe Liebchen , Johannes Wagener , Michael Irlbeck , Michael Zoller , Christina Scharf

CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm.

Case reports in critical care

Avec: Alice-Christin Acevedo , Michael Zoller , Christina Scharf , Uwe Liebchen , Michael Irlbeck , Ines Schroeder

The higher the better? Defining the optimal beta-lactam target for critically ill patients to reach infection resolution and improve outcome.

Journal of intensive care

Avec: Christina Scharf , Uwe Liebchen , Michael Paal , Max Taubert , Michael Vogeser , Michael Irlbeck , Michael Zoller , Ines Schroeder

The ONTAI study - a survey on antimicrobial dosing and the practice of therapeutic drug monitoring in German intensive care units.

Journal of critical care

Avec: U Liebchen , M Paal , C Scharf , I Schroeder , B Grabein , J Zander , C Siebers , M Zoller

Evaluation of the MeroRisk Calculator, A User-Friendly Tool to Predict the Risk of Meropenem Target Non-Attainment in Critically Ill Patients.

Antibiotics (Basel, Switzerland)

Avec: Uwe Liebchen , Marian Klose , Michael Paal , Michael Vogeser , Michael Zoller , Ines Schroeder , Lisa Schmitt , Wilhelm Huisinga , Robin Michelet , Johannes Zander , Christina Scharf , Ferdinand A Weinelt , Charlotte Kloft

The Role of Non-Enzymatic Degradation of Meropenem-Insights from the Bottle to the Body.

Antibiotics (Basel, Switzerland)

Avec: Uwe Liebchen , Sophie Rakete , Michael Vogeser , Florian M Arend , Christina Kinast , Christina Scharf , Michael Zoller , Ulf Schönermarck , Michael Paal

Target Site Pharmacokinetics of Meropenem: Measurement in Human Explanted Lung Tissue by Bronchoalveolar Lavage, Microdialysis, and Homogenized Lung Tissue.

Antimicrobial agents and chemotherapy

Avec: Michael Paal , Christina Scharf , Ann Katrin Denninger , Luis Ilia , Charlotte Kloft , Nikolaus Kneidinger , Uwe Liebchen , Sebastian Michel , Christian Schneider , Sebastian Schröpf , Carina Schuster , Michael Vogeser , Ferdinand Weinelt , Johannes Zander , Michael Zoller , Ines Schroeder

Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case-control study over 5 years.

Intensive care medicine

Avec: Boacheng Wang , Josef Briegel , Wolfgang A Krueger , Rika Draenert , Jette Jung , Alexandra Weber , Johannes Bogner , Sören Schubert , Uwe Liebchen , Sandra Frank , Michael Zoller , Michael Irlbeck , Ludwig Ney , Thomas Weig , Ludiwg Hinske , Sebastian Niedermayer , Erich Kilger , Patrick Möhnle , Beatrice Grabein

[Therapeutic drug monitoring and pharmacokinetic models as a strategy for rational antibiotic therapy in intensive care patients].

Die Anaesthesiologie

Avec: Lea Marie Schatz , Michael Zoller , Christina Scharf , Uwe Liebchen

Cefepime Population Pharmacokinetics, Antibacterial Target Attainment, and Estimated Probability of Neurotoxicity in Critically Ill Patients.

Antimicrobial agents and chemotherapy

Avec: Muhammad Bilal , Michael Zoller , Uwe Fuhr , Ulrich Jaehde , Sami Ullah , Uwe Liebchen , Sören Büsker , Johannes Zander , Baharak Babouee Flury , Max Taubert

Correlation between Bilirubin Elimination with the Cytokine Adsorber CytoSorb® and Mortality in Critically Ill Patients with Hyperbilirubinemia.

Blood purification

Avec: Caroline Gräfe , Michael Paal , Martin Winkels , Michael Irlbeck , Uwe Liebchen , Christina Scharf

Meropenem pharmacokinetics in cerebrospinal fluid: comparing intermittent and continuous infusion strategies in critically ill patients-a prospective cohort study.

Antimicrobial agents and chemotherapy

Avec: Sebastian G Wicha , Christina Kinast , Max Münchow , Sandra Wittova , Sebastian Greppmair , Alexandra K Kunzelmann , Michael Zoller , Michael Paal , Michael Vogeser , Katharina Habler , Thomas Weig , Nicole Terpolilli , Suzette Heck , Konstantinos Dimitriadis , Christina Scharf , Uwe Liebchen

Therapeutic drug monitoring-guided high dose meropenem therapy of a multidrug resistant

Respiratory medicine case reports

Avec: U Liebchen , M Paal , J Jung , I Schroeder , L Frey , M Zoller , C Scharf

Therapeutic Drug Monitoring of Meropenem and Piperacillin in Critical Illness-Experience and Recommendations from One Year in Routine Clinical Practice.

Antibiotics (Basel, Switzerland)

Avec: Christina Scharf , Michael Paal , Ines Schroeder , Michael Vogeser , Rika Draenert , Michael Irlbeck , Michael Zoller , Uwe Liebchen

Successful elimination of bilirubin in critically ill patients with acute liver dysfunction using a cytokine adsorber and albumin dialysis: a pilot study.

Scientific reports

Avec: Christina Scharf , Uwe Liebchen , Michael Paal , Andrea Becker-Pennrich , Michael Irlbeck , Michael Zoller , Ines Schroeder

Does Sample Size, Sampling Strategy, or Handling of Concentrations Below the Lower Limit of Quantification Matter When Externally Evaluating Population Pharmacokinetic Models?

European journal of drug metabolism and pharmacokinetics

Avec: Mehdi El Hassani , Uwe Liebchen , Amélie Marsot

Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting.

Intensive care medicine

Avec: Sebastian Greppmair , Alexander Brinkmann , Anka Roehr , Otto Frey , Stefan Hagel , Christoph Dorn , Amélie Marsot , Ibrahim El-Haffaf , Michael Zoller , Thomas Saller , Johannes Zander , Lea Marie Schatz , Christina Scharf , Josef Briegel , Iris K Minichmayr , Sebastian G Wicha , Uwe Liebchen

Correlation of bilirubin and toxic bile acids in critically ill patients with cholestatic liver dysfunction and adsorber application.

Scientific reports

Avec: Caroline Gräfe , Helen Graf , Vassilissa Wustrow , Uwe Liebchen , Philippe Conter , Michael Paal , Katharina Habler , Christina Scharf

Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum.

Journal of pharmaceutical and biomedical analysis

Avec: Katharina Habler , Mathias Brügel , Daniel Teupser , Uwe Liebchen , Christina Scharf , Ulf Schönermarck , Michael Vogeser , Michael Paal

Blood purification with a cytokine adsorber for the elimination of myoglobin in critically ill patients with severe rhabdomyolysis.

Critical care (London, England)

Avec: Christina Scharf , Uwe Liebchen , Michael Paal , Michael Irlbeck , Michael Zoller , Ines Schroeder

Comparative LC-MS/MS and HPLC-UV Analyses of Meropenem and Piperacillin in Critically Ill Patients.

Clinical laboratory

Avec: Michael Paal , Marcus Heilmann , Simone Koch , Thomas Bertsch , Jörg Steinmann , Rainer Höhl , Uwe Liebchen , Carina Schuster , Frederick M Kleine , Michael Vogeser

Isotope dilution LC-orbitrap-HRMS with automated sample preparation for the simultaneous quantification of 11 antimycotics in human serum.

Journal of pharmaceutical and biomedical analysis

Avec: Carina Schuster , Michael Paal , Johanna Lindner , Michael Zoller , Uwe Liebchen , Christina Scharf , Michael Vogeser

Comparing posaconazole and itraconazole for antifungal prophylaxis in critically ill lung transplant recipients: Efficacy and plasma concentrations.

Transplant infectious disease : an official journal of the Transplantation Society

Avec: Simon Kallee , Christina Scharf , Ines Schroeder , Michael Paal , Michael Vogeser , Michael Irlbeck , Johannes Zander , Michael Zoller , Jette Jung , Nikolaus Kneidinger , Christian Schneider , Sebastian Michel , Uwe Liebchen

Optimal loading dose of meropenem before continuous infusion in critically ill patients: a simulation study.

Scientific reports

Avec: Uwe Liebchen , Hanna Salletmeier , Simon Kallee , Christina Scharf , Lucas Huebner , Alexandra Weber , Michael Zoller

Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients.

International journal of antimicrobial agents

Avec: Lea Marie Schatz , Sebastian Greppmair , Alexandra K Kunzelmann , Johannes Starp , Alexander Brinkmann , Anka Roehr , Otto Frey , Stefan Hagel , Christoph Dorn , Michael Zoller , Christina Scharf , Sebastian G Wicha , Uwe Liebchen

Systematic Evaluation of Voriconazole Pharmacokinetic Models without Pharmacogenetic Information for Bayesian Forecasting in Critically Ill Patients.

Pharmaceutics

Avec: Simon Kallee , Christina Scharf , Lea Marie Schatz , Michael Paal , Michael Vogeser , Michael Irlbeck , Johannes Zander , Michael Zoller , Uwe Liebchen

[Hemoperfusion in anesthesia and intensive care medicine: benefits, risks, and evidence for different systems].

Die Anaesthesiologie

Avec: Caroline Gräfe , Lorenz Weidhase , Uwe Liebchen , Markus A Weigand , Christina Scharf

Extracorporeal adsorption of protective and toxic bile acids and bilirubin in patients with cholestatic liver dysfunction: a prospective study.

Annals of intensive care

Avec: Antonia Greimel , Katharina Habler , Caroline Gräfe , Nils Maciuga , Clara Isabell Brozat , Michael Vogeser , Michael Zoller , Felix L Happich , Uwe Liebchen , Sandra Frank , Michael Paal , Christina Scharf

Therapeutic Drug Monitoring of Elexacaftor, Tezacaftor, and Ivacaftor in Adult People with Cystic Fibrosis.

Journal of personalized medicine

Avec: Susanne Naehrig , Christina Shad , Magdalena Breuling , Melanie Goetschke , Katharina Habler , Sarah Sieber , Johanna Kastenberger , Alexandra Katharina Kunzelmann , Olaf Sommerburg , Uwe Liebchen , Juergen Behr , Michael Vogeser , Michael Paal

Réseau de co-auteurs

Christina Scharf 32 collaborations

Michael Zoller 29 collaborations

Michael Paal 25 collaborations

Michael Vogeser 16 collaborations

Michael Irlbeck 15 collaborations

Ines Schroeder 14 collaborations

Caroline Gräfe 7 collaborations

Katharina Habler 6 collaborations

Johannes Zander 6 collaborations

Lea Marie Schatz 5 collaborations

Ferdinand Weinelt 4 collaborations

Charlotte Kloft 4 collaborations

Alexander Brinkmann 4 collaborations

Otto Frey 4 collaborations

Sebastian Greppmair 4 collaborations

Simon Kallee 4 collaborations

Jette Jung 3 collaborations

Josef Briegel 3 collaborations

Max Taubert 3 collaborations

Thomas Weig 3 collaborations

Christina Kinast 3 collaborations

Christoph Dorn 3 collaborations

Stefan Hagel 3 collaborations

Antonia Greimel 3 collaborations

Felix L Happich 3 collaborations

Carina Schuster 3 collaborations

Sebastian G Wicha 3 collaborations

Robin Michelet 2 collaborations

Uwe Fuhr 2 collaborations

Suzette Heck 2 collaborations

Konstantinos Dimitriadis 2 collaborations

Nicole Terpolilli 2 collaborations

Markus A Weigand 2 collaborations

Martin Winkels 2 collaborations

Nils Maciuga 2 collaborations

Mathias Bruegel 2 collaborations

Lorenz Weidhase 2 collaborations

Hannah Kipka 2 collaborations

Roland Tomasi 2 collaborations

Max Hübner 2 collaborations

Christian Hagl 2 collaborations

Klaus T Wanner 2 collaborations

Hanna Mannell 2 collaborations

Georg Höfner 2 collaborations

Johannes Starp 2 collaborations

Erich Kilger 2 collaborations

Helen Graf 2 collaborations

Vassilissa Wustrow 2 collaborations

U Liebchen 2 collaborations

M Paal 2 collaborations

C Scharf 2 collaborations

I Schroeder 2 collaborations

M Zoller 2 collaborations

Ulf Schönermarck 2 collaborations

Nikolaus Kneidinger 2 collaborations

Sebastian Michel 2 collaborations

Christian Schneider 2 collaborations

Rika Draenert 2 collaborations

Alexandra Weber 2 collaborations

Sandra Frank 2 collaborations

Alexandra K Kunzelmann 2 collaborations

Amélie Marsot 2 collaborations

Anka Roehr 2 collaborations

Veronika Bucher 1 collaboration

Michael Weigand 1 collaboration

Zhendong Chen 1 collaboration

Chunli Chen 1 collaboration

Charalambos Dokos 1 collaboration

Constantin Lier 1 collaboration

Anka Röhr 1 collaboration

Georg Hempel 1 collaboration

Ute Chiriac 1 collaboration

Daniel Richter 1 collaboration

Otto R Frey 1 collaboration

Anka C Röhr 1 collaboration

Sophia Helbig 1 collaboration

Bettina Leber 1 collaboration

Lisa Rohrhofer 1 collaboration

Jennifer Weber 1 collaboration

Teresa Klaus 1 collaboration

Joerg Scheier 1 collaboration

Robert Sucher 1 collaboration

Philipp Stiegler 1 collaboration

Diana Rebholz 1 collaboration

Clara I Brozat 1 collaboration

Aljoscha Wegener 1 collaboration

Wolfgang Wilfert 1 collaboration

Karl Dichtl 1 collaboration

Johannes Wagener 1 collaboration

Alice-Christin Acevedo 1 collaboration

B Grabein 1 collaboration

J Zander 1 collaboration

C Siebers 1 collaboration

Marian Klose 1 collaboration

Lisa Schmitt 1 collaboration

Wilhelm Huisinga 1 collaboration

Ferdinand A Weinelt 1 collaboration

Sophie Rakete 1 collaboration

Florian M Arend 1 collaboration

Ann Katrin Denninger 1 collaboration

Luis Ilia 1 collaboration

Sebastian Schröpf 1 collaboration

Boacheng Wang 1 collaboration

Wolfgang A Krueger 1 collaboration

Johannes Bogner 1 collaboration

Sören Schubert 1 collaboration

Ludwig Ney 1 collaboration

Ludiwg Hinske 1 collaboration

Sebastian Niedermayer 1 collaboration

Patrick Möhnle 1 collaboration

Beatrice Grabein 1 collaboration

Muhammad Bilal 1 collaboration

Ulrich Jaehde 1 collaboration

Sami Ullah 1 collaboration

Sören Büsker 1 collaboration

Baharak Babouee Flury 1 collaboration

Max Münchow 1 collaboration

Sandra Wittova 1 collaboration

J Jung 1 collaboration

L Frey 1 collaboration

Andrea Becker-Pennrich 1 collaboration

Mehdi El Hassani 1 collaboration

Ibrahim El-Haffaf 1 collaboration

Thomas Saller 1 collaboration

Iris K Minichmayr 1 collaboration

Philippe Conter 1 collaboration

Mathias Brügel 1 collaboration

Daniel Teupser 1 collaboration

Marcus Heilmann 1 collaboration

Simone Koch 1 collaboration

Thomas Bertsch 1 collaboration

Jörg Steinmann 1 collaboration

Rainer Höhl 1 collaboration

Frederick M Kleine 1 collaboration

Johanna Lindner 1 collaboration

Hanna Salletmeier 1 collaboration

Lucas Huebner 1 collaboration

Clara Isabell Brozat 1 collaboration

Susanne Naehrig 1 collaboration

Christina Shad 1 collaboration

Magdalena Breuling 1 collaboration

Melanie Goetschke 1 collaboration

Sarah Sieber 1 collaboration

Johanna Kastenberger 1 collaboration

Alexandra Katharina Kunzelmann 1 collaboration

Olaf Sommerburg 1 collaboration

Juergen Behr 1 collaboration