Protéines de découplage mitochondrial : Questions médicales fréquentes
Nom anglais: Mitochondrial Uncoupling Proteins
Descriptor UI:D000071245
Tree Number:D12.776.575.750.688
Termes MeSH sélectionnés :
Reproduction
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Protéines de découplage mitochondrial : Questions médicales les plus fréquentes",
"headline": "Protéines de découplage mitochondrial : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Protéines de découplage mitochondrial : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-25",
"dateModified": "2025-04-19",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Protéines de découplage mitochondrial"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Protéines de transport de la membrane mitochondriale",
"url": "https://questionsmedicales.fr/mesh/D033681",
"about": {
"@type": "MedicalCondition",
"name": "Protéines de transport de la membrane mitochondriale",
"code": {
"@type": "MedicalCode",
"code": "D033681",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.575.750"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Protéine-1 de découplage",
"alternateName": "Uncoupling Protein 1",
"url": "https://questionsmedicales.fr/mesh/D000071256",
"about": {
"@type": "MedicalCondition",
"name": "Protéine-1 de découplage",
"code": {
"@type": "MedicalCode",
"code": "D000071256",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.575.750.688.500"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Protéine-2 de découplage",
"alternateName": "Uncoupling Protein 2",
"url": "https://questionsmedicales.fr/mesh/D000071246",
"about": {
"@type": "MedicalCondition",
"name": "Protéine-2 de découplage",
"code": {
"@type": "MedicalCode",
"code": "D000071246",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.575.750.688.750"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Protéine-3 de découplage",
"alternateName": "Uncoupling Protein 3",
"url": "https://questionsmedicales.fr/mesh/D000071247",
"about": {
"@type": "MedicalCondition",
"name": "Protéine-3 de découplage",
"code": {
"@type": "MedicalCode",
"code": "D000071247",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.575.750.688.875"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Protéines de découplage mitochondrial",
"alternateName": "Mitochondrial Uncoupling Proteins",
"code": {
"@type": "MedicalCode",
"code": "D000071245",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Colin J Barnstable",
"url": "https://questionsmedicales.fr/author/Colin%20J%20Barnstable",
"affiliation": {
"@type": "Organization",
"name": "Department of Neural and Behavioral Sciences, The Pennsylvania State University, Hershey, PA, 17033, USA. Electronic address: cbarnstable@pennstatehealth.psu.edu."
}
},
{
"@type": "Person",
"name": "Elena A Kotova",
"url": "https://questionsmedicales.fr/author/Elena%20A%20Kotova",
"affiliation": {
"@type": "Organization",
"name": "Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia."
}
},
{
"@type": "Person",
"name": "Yuri N Antonenko",
"url": "https://questionsmedicales.fr/author/Yuri%20N%20Antonenko",
"affiliation": {
"@type": "Organization",
"name": "Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia. antonen@belozersky.msu.ru."
}
},
{
"@type": "Person",
"name": "Ljudmila S Khailova",
"url": "https://questionsmedicales.fr/author/Ljudmila%20S%20Khailova",
"affiliation": {
"@type": "Organization",
"name": "Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia."
}
},
{
"@type": "Person",
"name": "Elena E Pohl",
"url": "https://questionsmedicales.fr/author/Elena%20E%20Pohl",
"affiliation": {
"@type": "Organization",
"name": "Department of Biomedical Sciences, Institute of Physiology, Pathophysiology and Biophysics, University of Veterinary Medicine, 1210 Vienna, Austria."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Effect of Anionic and Zeolite Supplements and Oral Calcium Bolus in Prepartum Diets on Feed Intake, Milk Yield and Milk Compositions, Plasma Ca Concentration, Blood Metabolites and the Prevalence of Some Reproductive Disorders in Fresh Dairy Cows.",
"datePublished": "2022-11-07",
"url": "https://questionsmedicales.fr/article/36359182",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ani12213059"
}
},
{
"@type": "ScholarlyArticle",
"name": "A chimeric porcine reproductive and respiratory syndrome virus 1 strain containing synthetic ORF2-6 genes can trigger T follicular helper cell and heterologous neutralizing antibody responses and confer enhanced cross-protection.",
"datePublished": "2024-03-06",
"url": "https://questionsmedicales.fr/article/38449049",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13567-024-01280-3"
}
},
{
"@type": "ScholarlyArticle",
"name": "A mixed methods process evaluation: understanding the implementation and delivery of HIV prevention services integrated within sexual reproductive health (SRH) with or without peer support amongst adolescents and young adults in rural KwaZulu-Natal, South Africa.",
"datePublished": "2024-07-03",
"url": "https://questionsmedicales.fr/article/38961492",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13063-024-08279-3"
}
},
{
"@type": "ScholarlyArticle",
"name": "The effect of UNIMMAP multiple micronutrient supplements versus iron-folic acid and placebo in anemia reduction among women of reproductive age in Kebribeyah Woreda, Somali Regional State, Ethiopia: a study protocol for a community-based individual RCT.",
"datePublished": "2024-03-06",
"url": "https://questionsmedicales.fr/article/38448918",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13063-024-08024-w"
}
},
{
"@type": "ScholarlyArticle",
"name": "The impact of an innovative community-based peer-led intervention on uptake and coverage of sexual and reproductive health services among adolescents and young people 15-24 years old: results from the Yathu Yathu cluster randomised trial.",
"datePublished": "2024-05-28",
"url": "https://questionsmedicales.fr/article/38807091",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s12889-024-18894-z"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Protéines mitochondriales",
"item": "https://questionsmedicales.fr/mesh/D024101"
},
{
"@type": "ListItem",
"position": 5,
"name": "Protéines de transport de la membrane mitochondriale",
"item": "https://questionsmedicales.fr/mesh/D033681"
},
{
"@type": "ListItem",
"position": 6,
"name": "Protéines de découplage mitochondrial",
"item": "https://questionsmedicales.fr/mesh/D000071245"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Protéines de découplage mitochondrial - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Protéines de découplage mitochondrial",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-12",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Protéines de découplage mitochondrial",
"description": "Comment diagnostiquer une dysfonction des UCP ?\nQuels tests sont utilisés pour évaluer les UCP ?\nLes biopsies musculaires sont-elles utiles ?\nQuels symptômes peuvent indiquer un problème d'UCP ?\nLes tests génétiques sont-ils fiables ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Protéines de découplage mitochondrial",
"description": "Quels sont les symptômes d'une suractivité des UCP ?\nComment une sous-activité des UCP se manifeste-t-elle ?\nLes UCP affectent-ils la température corporelle ?\nY a-t-il des symptômes neurologiques associés ?\nLes UCP influencent-elles le métabolisme des lipides ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Protéines de découplage mitochondrial",
"description": "Comment prévenir les dysfonctionnements des UCP ?\nLe stress oxydatif affecte-t-il les UCP ?\nLes antioxydants aident-ils à protéger les UCP ?\nL'alimentation influence-t-elle la santé mitochondriale ?\nLe tabagisme affecte-t-il les UCP ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Protéines de découplage mitochondrial",
"description": "Quels traitements ciblent les UCP ?\nL'exercice physique aide-t-il à réguler les UCP ?\nLes suppléments nutritionnels sont-ils bénéfiques ?\nY a-t-il des traitements expérimentaux ?\nComment la diète influence-t-elle les UCP ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Protéines de découplage mitochondrial",
"description": "Quelles complications peuvent survenir avec des UCP dysfonctionnelles ?\nLes UCP sont-elles liées à l'obésité ?\nLes maladies neurodégénératives sont-elles associées aux UCP ?\nLes UCP affectent-elles la santé cardiaque ?\nY a-t-il un lien entre UCP et diabète ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Protéines de découplage mitochondrial",
"description": "Quels facteurs de risque influencent les UCP ?\nL'âge affecte-t-il la fonction des UCP ?\nLes maladies génétiques influencent-elles les UCP ?\nLe mode de vie sédentaire impacte-t-il les UCP ?\nLe stress psychologique influence-t-il les UCP ?",
"url": "https://questionsmedicales.fr/mesh/D000071245?mesh_terms=Reproduction&page=731#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une dysfonction des UCP ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses biochimiques des mitochondries peuvent être effectués."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer les UCP ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent la mesure de la respiration mitochondriale et l'analyse des métabolites."
}
},
{
"@type": "Question",
"name": "Les biopsies musculaires sont-elles utiles ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles permettent d'évaluer la fonction mitochondriale et les niveaux d'UCP."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème d'UCP ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, intolérance à l'exercice et troubles métaboliques peuvent être des signes."
}
},
{
"@type": "Question",
"name": "Les tests génétiques sont-ils fiables ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent identifier des mutations spécifiques liées aux UCP."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une suractivité des UCP ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une suractivité peut entraîner une perte de poids et une intolérance au froid."
}
},
{
"@type": "Question",
"name": "Comment une sous-activité des UCP se manifeste-t-elle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut causer une prise de poids, une fatigue accrue et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Les UCP affectent-ils la température corporelle ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles jouent un rôle dans la thermogenèse et la régulation de la température."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles cognitifs et des douleurs neuropathiques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les UCP influencent-elles le métabolisme des lipides ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont impliquées dans la régulation du métabolisme lipidique et glucidique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les dysfonctionnements des UCP ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir un mode de vie sain avec une alimentation équilibrée et de l'exercice régulier."
}
},
{
"@type": "Question",
"name": "Le stress oxydatif affecte-t-il les UCP ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress oxydatif peut altérer la fonction des UCP, donc le réduire est crucial."
}
},
{
"@type": "Question",
"name": "Les antioxydants aident-ils à protéger les UCP ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les antioxydants peuvent réduire les dommages mitochondriaux et soutenir les UCP."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle la santé mitochondriale ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en nutriments favorise la santé mitochondriale et les UCP."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il les UCP ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut nuire à la fonction mitochondriale et aux UCP."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les UCP ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme les agonistes des UCP et des interventions diététiques peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il à réguler les UCP ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice peut améliorer la fonction mitochondriale et l'activité des UCP."
}
},
{
"@type": "Question",
"name": "Les suppléments nutritionnels sont-ils bénéfiques ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antioxydants et des acides gras oméga-3 peuvent soutenir la fonction des UCP."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques et des modulateurs de l'UCP sont en cours d'étude."
}
},
{
"@type": "Question",
"name": "Comment la diète influence-t-elle les UCP ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diète riche en acides gras insaturés peut stimuler l'activité des UCP."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des UCP dysfonctionnelles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles métaboliques, des maladies cardiovasculaires et des problèmes neurologiques."
}
},
{
"@type": "Question",
"name": "Les UCP sont-elles liées à l'obésité ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une dysfonction des UCP peut contribuer à l'obésité et à la résistance à l'insuline."
}
},
{
"@type": "Question",
"name": "Les maladies neurodégénératives sont-elles associées aux UCP ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des UCP peuvent être impliquées dans des maladies comme Alzheimer."
}
},
{
"@type": "Question",
"name": "Les UCP affectent-elles la santé cardiaque ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des UCP dysfonctionnelles peuvent augmenter le risque de maladies cardiaques."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre UCP et diabète ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des UCP peuvent influencer le métabolisme du glucose et le diabète."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque influencent les UCP ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'alimentation, le mode de vie sédentaire et le stress oxydatif sont des facteurs clés."
}
},
{
"@type": "Question",
"name": "L'âge affecte-t-il la fonction des UCP ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut altérer la fonction mitochondriale et des UCP."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques influencent-elles les UCP ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines mutations génétiques peuvent affecter la production et la fonction des UCP."
}
},
{
"@type": "Question",
"name": "Le mode de vie sédentaire impacte-t-il les UCP ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire peut réduire l'activité des UCP et la santé mitochondriale."
}
},
{
"@type": "Question",
"name": "Le stress psychologique influence-t-il les UCP ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut affecter la fonction mitochondriale et des UCP."
}
}
]
}
]
}
Hypocalcaemia is an important disorder associated with an increased risk of metabolic diseases, and many studies have been going on for decades. This study investigated the effects of anionic and zeol...
The prevalence of porcine reproductive and respiratory syndrome virus 1 (PRRSV1) isolates has continued to increase in Chinese swine herds in recent years. However, no effective control strategy is av...
Combination prevention interventions, when integrated with community-based support, have been shown to be particularly beneficial to adolescent and young peoples' sexual and reproductive health. Betwe...
The process evaluation was conducted in accordance with the Medical Research Council guidelines using quantitative and qualitative approaches. Self-completed surveys and clinic and programmatic data w...
The intervention was feasible and acceptable to young people and intervention implementing teams. In particular, the STI testing and SRH components of the intervention were popular. The main challenge...
The results demonstrated that peer-led community-based care that integrates SRH services with HIV is a versatile model to decentralise health and social care. The family could be a platform to target ...
Women of reproductive age (WRA) in developing countries are often at risk of micronutrient deficiencies due to inadequate intakes and excessive losses....
The purpose of this trial is to assess the effectiveness of United Nations International Multiple Micronutrient Antenatal Preparation-Multiple Micronutrient Supplements (UNIMMAP-MMS) versus iron-folic...
Three parallel groups of WRA will participate in a community-based, individually randomized, double-blinded, placebo-controlled superiority trial. After consent, the sample of 375 mildly or moderately...
The World Health Organization (WHO) added UNIMMAP-MMS to its essential medicine lists in 2021 but recommended rigorous study. Several factors in addition to inadequate intakes of iron and folic acid c...
ClinicalTrials.gov NCT05682261. Registered on January 12, 2023....
The Yathu Yathu ("For Us, By Us") cluster-randomized trial (CRT) evaluated a peer-led community-based sexual and reproductive health(SRH) intervention implemented to address persistent barriers to SRH...
The trial was conducted from Jul 2019-Oct 2021 in two urban communities in Lusaka, Zambia, divided into 20 zones (~ 2350 AYP/zone). Zones were randomly allocated to intervention (N = 10) or control (N...
Among enumerated AYP, 93.6% (14,872/15,894) consented to participate from intervention zones and 95.1% (14,500/15,255) from control zones. Among those who accepted a PPC, 63.8% (9,493/14,872) accessed...
The Yathu Yathu intervention increased coverage of key SRH services among AYP and reached two-thirds of AYP. These findings demonstrate the potential of providing peer-led community-based SRH services...
ISRCTN75609016 (11/10/2021), clinicaltrials.gov number NCT04060420 (19/08/2019); retrospectively registered....
To better study the effect of sperm deoxyribonucleic acid fragmentation (SDF) on intracytoplasmic sperm injection (ICSI) outcomes from an ovum donation program by assessing the cumulative live birth r...
A multicenter retrospective cohort study was conducted, and the Kaplan-Meier survival curves were generated to calculate the CLBR with regard to the SDF degree....
Private university-affiliated in vitro fertilization centers....
Data from 864 couples using donated eggs and undergoing ICSI from 2000 to 2019 were analyzed. Sperm deoxyribonucleic acid fragmentation was measured using terminal deoxynucleotidyl transferase biotin ...
None....
Live birth rate (LBR) per first ET and per all consecutive ETs within the same patient and CLBR per ET, per EmbR, and per MII oocyte used considering the SDF level....
A total of 1,903 ICSI cycles were considered, encompassing 6,340 donated oocytes, 2,543 embryos, and 1,145 ETs. Comparing ≤15% SDF (low) with >15% SDF (high) or by 10% SDF ranges, the LBRs per first E...
Elevated SDF does not reduce the LBR or cumulative probability to obtain a child when calculated per ET, per EmbR, and per donated MII oocyte used in couples undergoing ICSI cycles....
Oxidative stress plays a leading role in the pathogenesis of diabetic nephropathy. However, many aspects of oxidative stress reactions in the initial stages of this disease are not fully understood. T...
Girls' and women's health as well as social and economic wellbeing are often negatively impacted by early childbearing. In many parts of Africa, adolescent girls who get pregnant often drop out of sch...
The three interventions we will assess are: a cash transfer conditioned on (re)enrolment into school or vocational training, subsidized childcare, and life skills training offered through adolescent m...
We will conduct a baseline survey among adolescent mothers aged 10-19 years (N = 270, per site) enrolled following a household listing in select enumeration areas in each site. Adolescent mothers will...
Our research will generate evidence that provides insights on interventions that can enable adolescent mothers to continue their education, as well as improve their SRH and mental health. We aim to ma...
Due to the influence of economic, social and many other factors, there are more and more reproductive problems. Originally introduced for managing male factor infertility, intracytoplasmic sperm injec...
HIV-related stigma and discrimination significantly affects health, and well-being, willingness to be tested for HIV, initiation and adherence to antiretroviral therapy, and quality of life. However, ...
The appended and most recent Demographic and Health Survey dataset of three sub-Saharan African countries from 2021 to 2022 was used for data analysis. A total of 56,690 women aged 15-49 years were in...
The overall prevalence of discriminatory attitudes against people living with HIV/AIDS was 28.19% (95% CI: 27.74%, 28.64%). In the multivariable analysis, individual level (being young, being an inter...
The prevalence of discriminatory attitudes against people living with HIV/AIDS in three sub-Saharan African countries was high. Individual and community-level variables were associated with discrimina...