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Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Molécules d'interaction stromale
Molécules d'interaction stromale : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Biopsie
Immunohistochimie
Marqueurs tumoraux
Tumeurs
Imagerie par résonance magnétique
Interactions cellulaires
Biopsie
Analyse histologique
Symptômes
5
Croissance tumorale
Symptômes
Tumeurs
Environnement tumoral
Symptômes précoces
Symptômes tardifs
Traitement
Réversibilité des symptômes
Prévention
5
Prévention
Facteurs de risque
Mode de vie sain
Prévention des tumeurs
Dépistage
Détection précoce
Éducation sur le cancer
Sensibilisation
Vaccins
Prévention du cancer
Traitements
5
Thérapies ciblées
Immunothérapie
Efficacité des traitements
Tumeurs
Effets secondaires
Réactions immunitaires
Médecine personnalisée
Profil moléculaire
Thérapies combinées
Efficacité des traitements
Complications
5
Progression tumorale
Complications
Gestion des complications
Suivi médical
Prévisibilité
Interactions tumorales
Qualité de vie
Complications
Facteurs de risque
5
Facteurs de risque
Inflammation chronique
Alimentation
Antioxydants
Antécédents familiaux
Prédisposition génétique
Toxines
Exposition environnementale
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"@type": "Question",
"name": "Quels tests sont utilisés pour les molécules stromales ?",
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"@type": "Question",
"name": "Les interactions stromales causent-elles des symptômes ?",
"position": 7,
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"@type": "Question",
"name": "Comment les symptômes varient-ils selon les tumeurs ?",
"position": 8,
"acceptedAnswer": {
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"text": "Les symptômes dépendent du type de tumeur et de l'environnement stromal spécifique."
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{
"@type": "Question",
"name": "Les symptômes sont-ils précoces ou tardifs ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent être précoces ou tardifs, selon la nature de l'interaction stromale."
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{
"@type": "Question",
"name": "Les symptômes sont-ils réversibles ?",
"position": 10,
"acceptedAnswer": {
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"text": "Certains symptômes peuvent s'améliorer avec un traitement ciblant les interactions stromales."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les interactions stromales ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par la réduction des facteurs de risque liés aux tumeurs et à l'inflammation."
}
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"@type": "Question",
"name": "Quels modes de vie aident à prévenir les tumeurs ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, peut réduire les risques."
}
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"@type": "Question",
"name": "Les dépistages réguliers sont-ils utiles ?",
"position": 13,
"acceptedAnswer": {
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"text": "Oui, les dépistages peuvent aider à détecter les tumeurs précocement, limitant les interactions stromales."
}
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{
"@type": "Question",
"name": "L'éducation sur le cancer est-elle importante ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, l'éducation aide à sensibiliser aux facteurs de risque et aux signes précoces de cancer."
}
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{
"@type": "Question",
"name": "Les vaccins peuvent-ils prévenir les tumeurs ?",
"position": 15,
"acceptedAnswer": {
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"text": "Certains vaccins, comme ceux contre le HPV, peuvent réduire le risque de cancers associés."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les molécules stromales ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des immunothérapies sont en développement pour cibler ces molécules."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité varie selon le type de tumeur et la nature des interactions stromales."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires des traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent entraîner des effets secondaires, notamment des réactions immunitaires."
}
},
{
"@type": "Question",
"name": "Comment les traitements sont-ils personnalisés ?",
"position": 19,
"acceptedAnswer": {
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"text": "Les traitements sont adaptés en fonction du profil moléculaire de la tumeur et de l'environnement stromal."
}
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"@type": "Question",
"name": "Les traitements sont-ils combinés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des combinaisons de traitements sont souvent utilisées pour améliorer l'efficacité."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la progression tumorale, la résistance au traitement et la métastase."
}
},
{
"@type": "Question",
"name": "Les interactions stromales aggravent-elles les complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent favoriser la progression tumorale et compliquer le traitement."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion implique des traitements ciblés et un suivi régulier pour adapter les thérapies."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être anticipées en fonction du type de tumeur et des interactions."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement impacter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque des interactions stromales ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'inflammation chronique, le tabagisme et des prédispositions génétiques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en antioxydants peut réduire les risques d'interactions stromales."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut influencer l'inflammation et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancer peuvent augmenter le risque d'interactions stromales."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines est-elle un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des substances toxiques peut favoriser les interactions stromales et le cancer."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 02/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, London, ON, N6A 5C1, Canada. Electronic address: pstatho@uwo.ca.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada. Electronic address: mikura@uhnresearch.ca.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A5C1, Canada.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering & Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering, Siming south road 422, 3012, Xiamen, CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics, Indiana University Indianapolis, Indianpolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Hadhramout University, Faculty of Medicine and Health Sciences, Department of Basic Medical Sciences, Hadhramout, Yemen
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Publications dans "Molécules d'interaction stromale" :
To evaluate the effect of placental location on the severity of placenta accreta spectrum (PAS)....
We analyzed 390 patients with placenta previa combined with placenta accreta spectrum who underwent cesarean section between January 1, 2014 and December 30, 2020 in the electronic case database of th...
The history of cesarean delivery rates in the anterior group (91.67%) and the non-central group (85.71%) were statistically different from the posterior group (63.74%)(P < 0.001). Univariate logistic ...
Compared with posterior placenta, anterior and non-central placenta are independent risk factors for invasive PAS in patients with placenta previa, during which we should be more cautious in treatment...
Placenta accreta spectrum (PAS) is one of the most dangerous conditions in pregnancy and is increasing in frequency. The risk of life-threatening bleeding is present throughout pregnancy but is partic...
We are pleased to present this Special Issue of the...
Preeclampsia (PE) is a hypertensive pregnancy disorder linked to placental dysfunction, often involving pathological lesions like acute atherosis, decidual vasculopathy, accelerated villous maturation...
A total of 168 placental whole-slide images (WSIs) of patients from Seoul National University Hospital (comprising 84 PE cases and 84 normal controls) were used for model development and internal vali...
Using ensemble modeling, we developed a model to identify PE placentas. The model showed good performance (area under the precision-recall curve [AUPRC], 0.771; 95% confidence interval [CI], 0.752-0.7...
The proposed computational pathology model demonstrated a strong ability to identify preeclamptic placentas. Computational pathology has the potential to improve the identification of PE placentas....
This study aimed to identify if placental thickness measured from MRI images correlated with placenta percreta in patients with placenta previa....
Placental thickness was retrospectively measured in 161 patients from July 2018 to August 2020. The measurements were performed at the thickest part of the placenta in the lower uterine segment on the...
Placental thickness in patients with placenta percreta was significantly higher than in patients with placenta increta, placenta accreta, and normal placentas (p < 0.05). Multivariate analysis reveale...
Patients with placenta percreta had the highest placental thickness. Placental thickness was correlated with placenta percreta....
The objective of this study was to assess the performance of ultrasound and magnetic resonance imaging (MRI) features in helping to classify the type of placenta accreta spectrum (PAS; accreta/increta...
We conducted a retrospective study in 82 pregnant women with PAS who underwent ultrasound and MRI examination of the pelvis before delivery (from an initial cohort of 185 women with PAS). We estimated...
Among the 82 patients, 29 (35%) had placenta accreta/increta and 53 (65%) had placenta percreta. The best features to discriminate between placenta accreta/increta and placenta percreta with ultrasoun...
The nomogram we developed to predict the risk of placenta percreta among patients with PAS had good discriminative capabilities. This performance and its impact on maternal morbidity should be confirm...
Although historically pre-eclampsia, preterm birth, abruption, fetal growth restriction and stillbirth have been viewed as clinically distinct entities, a growing body of literature has demonstrated t...
Placental accreta spectrum (PAS) disorder with bladder involvement can be associated with maternal and neonatal morbidity. Magnetic resonance imaging (MRI) may provide accurate preoperative diagnoses....
This study had 2 aims: to retrospectively review the MRI findings for bladder involvement in PAS with placental previa and to correlate bladder involvement with maternal and neonatal outcomes....
MRI images of 48 patients with severe PAS (increta and percreta) with placenta previa/low-lying placenta were evaluated by 2 experienced radiologists blinded to the final diagnoses. Nine MRI findings ...
Of the 48 patients, 27 did not have bladder involvement, while 21 did. Logistic regression analysis identified 2 predictive MRI features for bladder involvement. They were abnormal vascularization (OR...
PAS with bladder involvement was significantly correlated with massive surgical blood loss. Prenatally, the disorder was predicted with high specificity by the combination of loss of chemical shift ar...
To determine the rate of resolution of placenta previa and low-lying placenta (LLP) and the effect of pelvic rest recommendations on the timing of follow-up imaging....
Retrospective review of pregnancies with previa/LLP detected on mid-trimester exam at our ultrasound unit from 2019 to 2021. LLP was defined as the lower edge of placenta located within 2 cm of the in...
Exactly 144 patients had previa and 266 had LLP on the mid-trimester exam with complete records. Previa resolution happened in 51.4% (74/144) of cases. Exactly 62% (46/74) of previa resolutions occurr...
Most societies recommend follow-up imaging at 32 weeks; however, our results suggest this may be done sooner and closer to 28 weeks. Pelvic rest did not affect timing of repeat imaging or delivery....
To determine whether women who experience resolution of low placentation (low-lying placenta or placenta previa) are at increased risk of postpartum hemorrhage compared to those with normal placentati...
This was a retrospective cohort study of women who delivered at Mount Sinai Hospital between 2015 and 2019, and who were diagnosed with low-lying placenta or placenta previa on transvaginal ultrasound...
A total of 1256 women were identified for analysis, of whom 628 had resolved low placentation and 628 had normal placentation. Women with resolved low placentation, compared to those with normal place...
Despite high rates of resolution of low-lying placenta and placenta previa by term, women with resolved low placentation remain at increased risk of postpartum hemorrhage compared to those with normal...