Quels facteurs de risque sont étudiés avec les A549 ?
Des facteurs comme le tabagisme, l'exposition à des agents chimiques et la pollution.
Facteurs de risquePollution
#2
Les A549 aident-elles à identifier des facteurs génétiques ?
Elles peuvent être utilisées pour étudier l'expression génique liée à des prédispositions au cancer.
Facteurs génétiquesExpression génique
#3
Comment les A549 sont-elles utilisées pour étudier l'environnement ?
Elles permettent d'évaluer l'impact des toxines environnementales sur les cellules pulmonaires.
Toxines environnementalesImpact environnemental
#4
Peut-on étudier l'alimentation avec les A549 ?
Indirectement, elles peuvent être utilisées pour explorer l'impact des nutriments sur le cancer.
AlimentationNutriments
#5
Les A549 sont-elles utiles pour étudier le stress oxydatif ?
Oui, elles sont souvent utilisées pour examiner les effets du stress oxydatif sur les cellules.
Stress oxydatifCellules
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"@type": "Question",
"name": "Quelles techniques sont utilisées pour étudier les cellules A549 ?",
"position": 2,
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"@type": "Question",
"name": "Les cellules A549 sont-elles tumorales ?",
"position": 3,
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"@type": "Question",
"name": "Peut-on détecter des marqueurs spécifiques dans les A549 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des marqueurs comme le CD44 et le p53 peuvent être analysés dans les A549."
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"@type": "Question",
"name": "Les cellules A549 sont-elles sensibles à des médicaments ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont souvent utilisées pour tester la sensibilité aux chimiothérapies."
}
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{
"@type": "Question",
"name": "Quels symptômes sont associés aux cellules A549 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les cellules A549 ne présentent pas de symptômes, car elles sont in vitro."
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"@type": "Question",
"name": "Les cellules A549 peuvent-elles simuler des symptômes humains ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent être utilisées pour étudier des symptômes liés aux maladies pulmonaires."
}
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{
"@type": "Question",
"name": "Comment les A549 aident-elles à comprendre les symptômes du cancer ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'étudier la réponse des cellules tumorales aux traitements et aux facteurs de croissance."
}
},
{
"@type": "Question",
"name": "Les cellules A549 montrent-elles des signes de stress cellulaire ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent montrer des signes de stress en réponse à des agents cytotoxiques."
}
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{
"@type": "Question",
"name": "Peut-on observer des symptômes de résistance dans les A549 ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent être utilisées pour étudier la résistance aux médicaments anticancéreux."
}
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{
"@type": "Question",
"name": "Les cellules A549 aident-elles à la prévention du cancer ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, elles sont utilisées pour étudier les mécanismes de la carcinogenèse."
}
},
{
"@type": "Question",
"name": "Comment les A549 contribuent-elles à la recherche préventive ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'identifier des biomarqueurs et des cibles pour la prévention du cancer."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser les A549 pour étudier des facteurs de risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont utilisées pour étudier l'impact de divers facteurs environnementaux sur le cancer."
}
},
{
"@type": "Question",
"name": "Les A549 sont-elles utiles pour la recherche sur le tabagisme ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont souvent utilisées pour étudier les effets du tabagisme sur les cellules pulmonaires."
}
},
{
"@type": "Question",
"name": "Comment les A549 aident-elles à comprendre la prévention des maladies ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'explorer les mécanismes de protection et les interventions préventives."
}
},
{
"@type": "Question",
"name": "Quels traitements sont testés sur les cellules A549 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements anticancéreux et les thérapies ciblées sont souvent testés sur ces cellules."
}
},
{
"@type": "Question",
"name": "Les A549 sont-elles utilisées pour des essais cliniques ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, elles sont utilisées pour des études précliniques et non pour des essais cliniques directs."
}
},
{
"@type": "Question",
"name": "Comment les A549 aident-elles à développer de nouveaux traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'évaluer l'efficacité et la toxicité des nouveaux composés thérapeutiques."
}
},
{
"@type": "Question",
"name": "Les cellules A549 peuvent-elles prédire la réponse au traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent fournir des indications sur la réponse aux traitements, mais ne sont pas définitives."
}
},
{
"@type": "Question",
"name": "Quels agents sont souvent testés sur les A549 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des agents chimiothérapeutiques comme le cisplatine et des inhibiteurs de tyrosine kinase."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent être étudiées avec les A549 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'étudier les complications liées aux traitements du cancer et aux métastases."
}
},
{
"@type": "Question",
"name": "Les A549 peuvent-elles simuler des complications pulmonaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont utilisées pour modéliser des complications comme la fibrose pulmonaire."
}
},
{
"@type": "Question",
"name": "Comment les A549 aident-elles à comprendre les complications du cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'étudier les interactions entre les cellules tumorales et le microenvironnement."
}
},
{
"@type": "Question",
"name": "Peut-on étudier la résistance aux traitements avec les A549 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont souvent utilisées pour comprendre les mécanismes de résistance aux traitements."
}
},
{
"@type": "Question",
"name": "Les A549 sont-elles impliquées dans des complications métaboliques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent être utilisées pour étudier les effets métaboliques des traitements anticancéreux."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont étudiés avec les A549 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs comme le tabagisme, l'exposition à des agents chimiques et la pollution."
}
},
{
"@type": "Question",
"name": "Les A549 aident-elles à identifier des facteurs génétiques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent être utilisées pour étudier l'expression génique liée à des prédispositions au cancer."
}
},
{
"@type": "Question",
"name": "Comment les A549 sont-elles utilisées pour étudier l'environnement ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent d'évaluer l'impact des toxines environnementales sur les cellules pulmonaires."
}
},
{
"@type": "Question",
"name": "Peut-on étudier l'alimentation avec les A549 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, elles peuvent être utilisées pour explorer l'impact des nutriments sur le cancer."
}
},
{
"@type": "Question",
"name": "Les A549 sont-elles utiles pour étudier le stress oxydatif ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont souvent utilisées pour examiner les effets du stress oxydatif sur les cellules."
}
}
]
}
]
}
Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China. Electronic address: taolm@ecust.edu.cn.
Will Rogers Institute Pulmonary Research Center and Hastings Center for Pulmonary Research, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Will Rogers Institute Pulmonary Research Center and Hastings Center for Pulmonary Research, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Physiology and Neurosciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA.
Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Sonny Astani Department of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Will Rogers Institute Pulmonary Research Center and Hastings Center for Pulmonary Research, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
The objective of this study was to investigate the predictability of overbite correction in patients with deepbite using the clear aligners (Invisalign, Align Technology, San Jose, Calif) and examine ...
This retrospective study included 24 deepbite patients (10 males and 14 females; aged 32.8 ± 11.9 years; an initial overbite of 5.20 ± 0.95 mm; an average treatment period of 11.04 ± 4.14 months) cons...
Mean overbite correction was 33%, with a 1.15 mm improvement after the first set of aligners. All teeth demonstrated statistically significant differences between planned and achieved amounts in verti...
Clear aligner treatment showed an average of 33% overbite correction. Overcorrection and additional refinement treatments are needed in most patients with a deepbite....
Although the Invisalign appliance has reported difficulty in achieving the overbite outcomes predicted by ClinCheck software (Align Technology, Santa Clara, Calif), the effect of modifications to the ...
A retrospective study was conducted using pretreatment and posttreatment intraoral scans and predicted outcomes (ClinCheck) stereolithography files of 2 groups of consecutively treated adult patients ...
The regression coefficient analysis indicated that for both groups, the deeper the pretreatment overbite and the greater overbite reduction projected according to ClinCheck, there is a linear increase...
The use of precision bite ramps does not appear to significantly improve the ability of SmartTrack material to predictably open the bite. SmartTrack material with or without bite ramps does not appear...
Deep overbite has been shown to be difficult to correct with clear aligners. Optimized deep bite attachments are reported to facilitate deep bite correction with aligners. The aim of this retrospectiv...
This was a retrospective cohort study. The pretreatment and post-treatment intraoral scans of patients with deep overbite treated with Invisalign clear aligners were accessed. Patients were divided in...
Seventy-eight patients were included. There was no statistically significant difference in overbite reduction between patients who had conventional versus optimized attachments. The amount of overbite...
Deep overbite correction with aligners remains difficult regardless of the type of attachment used. Optimized attachments are no more effective than using conventional attachments in reducing deep ove...
When correcting deep bite with clear aligners, the attachment type does not improve the success rate. Clinicians should plan to overcorrect deep bite reduction to expect only 33% to 40% of their plann...
This study sought to correct the assessment of orthodontic camouflage treatment to provide a harmonized soft-tissue profile, consistent occlusion, and a pleasant smile....
Class-II, division 2 malocclusions can be treated through dental compensation and growth modification methods instead of surgical-orthodontic treatment, which can be determined by the growth and age o...
This case report was of a 14-year-old Chinese female whose chief complaint was crowding of anterior teeth and required treatment for the same. On necessary clinical and radiographical examination, dia...
Using a utility arch with orthodontic camouflage treatment can help to reinforce molar anchoring and improve a deep bite in the maxillary dentitions. The patient was treated with the devised treatment...
To correct a maxillomandibular discrepancy, an orthodontist may conduct a process known as camouflage therapy without necessity of surgery. However, patient selection forms a crucial role, and hence s...
This retrospective study used cone-beam computed tomography to investigated the crown-root morphology and alveolar bone structure in incisors region in subjects with closed deep overbite and compariso...
This prospective study aimed to compare regional soft tissue changes between patients with class III overbite and open bite deformities treated with bimaxillary surgery involving clockwise and counter...
Class III deformity adults receiving Le Fort I and bilateral sagittal split osteotomies were grouped according to the incisal occlusion: overbite (n = 30) and open bite (n = 30). Combined cone-beam CT...
Postoperative changes for the overbite and open bite groups included anterior repositioning of nose (-0.8 ± 1.2 mm and -1.1 ± 1.1 mm, respectively) and cheek (-1.9 ± 1.3 mm and -1.7 ± 2.6 mm, respecti...
Treatment of class III overbite and open bite deformities with bimaxillary rotational surgery resulted in comparable regional soft tissue changes, except for upper lip, lower lip and chin....
To investigate whether the predicted changes in overbite (OB) and overjet (OJ) in Align Technology's (Santa Jose, Calif) digital treatment plan for the prescribed course of treatment with the Invisali...
Geomagic Control X software was used to determine OB and OJ differences between the pretreatment and predicted outcome. STL files for patients satisfying inclusion criteria and undergoing nonextractio...
Data regarding 76 adult patients who satisfied strict inclusion criteria were assessed. The Shapiro-Wilks test indicated normality (P > .05). The Bland-Altman analysis showed high levels of agreement ...
Clinicians and researchers can be confident that measurement data provided by Invisalign's ClinCheck digital treatment-planning facility concerning OB and OJ changes from the initial to the predicted ...
To determine recognition ability and the levels of esthetic tolerance of deep bite and anterior open bite (AOB) among laypeople and investigate the factors affecting levels of tolerance....
Using a questionnaire, laypeople (N = 100) were examined, and overbite was measured. They were tested for whether they recognized deep bite and AOB. Esthetic tolerance thresholds for deep bite and AOB...
Of the participants, 55% and 94% recognized deep bite and AOB, respectively. Participants with a deep bite were significantly more likely to esthetically tolerate deep bite compared with those without...
Participants with a deep bite or those who did not recognize a deep bite had significantly higher esthetic tolerance of deep bite than those without or those who recognized the problem (P < .05)....
To determine the association between the facial biotype, the overbite and the overjet in digital lateral skull radiographs....
230 digital skull lateral radiographs of patients with permanent dentition with 18 to 55 years old were used as sample. The VERT index and the Ricketts analysis were considered to identify the facial ...
The facial biotype with the highest prevalence was dolichofacial with 36.52% (n=84), being more frequent in the female sex. However, the mesofacial biotype predominated in the male sex. On the other h...
With the results obtained, it is concluded that there is an association between facial biotype, overbite and overjet....
To determine whether achieved outcome regarding overjet and overbite matched the predicted outcome following treatment with Invisalign (Align Technology, San Jose, Calif) aligner appliances....
Data including pretreatment, predicted and achieved overjet, and overbite measurements provided by Align's digital treatment facility, ClinCheck Pro, were evaluated. Descriptive statistics, Mann-Whitn...
From an initial sample of 600, 355 adult patients satisfied the inclusion and exclusion criteria. ICC scores for data input were excellent. Median (interquartile range [IQR]) age was 30.14 (23.33, 39....
Achieved overjet and overbite measurements differed significantly from the predicted outcomes at the end of an initial sequence of aligners. Planned increases in overbite resulted in greater overbite ...
