Is implementation science a science? Not yet.
Getting the science right for implementation is critical for making the processes for improving outcomes more predictable and effective in global public health. Unfortunately, "implementation science"...
Benzènesulfonates : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer une exposition aux benzènesulfonates ?
Le diagnostic repose sur l'historique d'exposition et des tests biologiques spécifiques.
#2
Quels tests sont utilisés pour détecter les benzènesulfonates ?
Des analyses de sang et d'urine peuvent être effectuées pour détecter ces composés.
#3
Quels symptômes indiquent une intoxication aux benzènesulfonates ?
Les symptômes incluent des maux de tête, des nausées et des irritations cutanées.
#4
Les benzènesulfonates sont-ils détectables par imagerie ?
Non, l'imagerie ne permet pas de détecter les benzènesulfonates, seuls des tests biologiques le peuvent.
#5
Y a-t-il des marqueurs biologiques pour les benzènesulfonates ?
Oui, des métabolites spécifiques peuvent être mesurés dans les fluides corporels.
Symptômes 5
#1
Quels sont les symptômes d'une exposition aiguë ?
Les symptômes incluent des vertiges, des nausées et des irritations des voies respiratoires.
#2
Les benzènesulfonates provoquent-ils des allergies ?
Oui, ils peuvent provoquer des réactions allergiques cutanées chez certaines personnes.
#3
Quels effets à long terme peuvent causer les benzènesulfonates ?
Une exposition prolongée peut entraîner des troubles respiratoires et des problèmes dermatologiques.
#4
Les benzènesulfonates affectent-ils le système nerveux ?
Oui, une exposition peut causer des troubles neurologiques comme des maux de tête persistants.
#5
Peut-on ressentir des symptômes digestifs ?
Oui, des symptômes comme des nausées et des douleurs abdominales peuvent survenir.
Prévention 5
#1
Comment prévenir l'exposition aux benzènesulfonates ?
Utiliser des équipements de protection individuelle et suivre les protocoles de sécurité.
#2
Des formations sont-elles nécessaires pour manipuler ces composés ?
Oui, des formations sur la sécurité chimique sont essentielles pour les travailleurs.
#3
Quels équipements de protection sont recommandés ?
Des gants, des masques et des lunettes de protection sont recommandés.
#4
Les fuites de benzènesulfonates doivent-elles être signalées ?
Oui, toute fuite doit être signalée immédiatement aux autorités compétentes.
#5
Comment stocker les benzènesulfonates en toute sécurité ?
Les stocker dans des contenants hermétiques et dans un endroit bien ventilé.
Traitements 5
#1
Quel traitement pour une intoxication aux benzènesulfonates ?
Le traitement consiste à éliminer l'exposition et à gérer les symptômes cliniques.
#2
Des antidotes existent-ils pour les benzènesulfonates ?
Il n'existe pas d'antidote spécifique, le traitement est symptomatique.
#3
Comment traiter les irritations cutanées causées par ces composés ?
Utiliser des crèmes apaisantes et éviter tout contact avec le produit irritant.
#4
Les soins d'urgence sont-ils nécessaires ?
Oui, en cas d'exposition sévère, des soins d'urgence peuvent être requis.
#5
Quels médicaments peuvent aider en cas d'exposition ?
Des antihistaminiques peuvent être prescrits pour les réactions allergiques.
Complications 5
#1
Quelles complications peuvent survenir après exposition ?
Des complications respiratoires et dermatologiques peuvent se développer après exposition.
#2
Les benzènesulfonates peuvent-ils causer des cancers ?
Des études suggèrent un lien potentiel avec certains types de cancers, mais des recherches sont nécessaires.
#3
Y a-t-il des effets sur la reproduction ?
Une exposition prolongée pourrait affecter la fertilité, mais des études supplémentaires sont requises.
#4
Les benzènesulfonates affectent-ils le développement des enfants ?
Des recherches indiquent des risques potentiels pour le développement, nécessitant une attention particulière.
#5
Peut-on développer une sensibilisation aux benzènesulfonates ?
Oui, une sensibilisation peut se développer, entraînant des réactions allergiques plus graves.
Facteurs de risque 5
#1
Qui est le plus à risque d'exposition ?
Les travailleurs dans l'industrie chimique et ceux manipulant des produits contenant ces composés.
#2
Les enfants sont-ils plus vulnérables ?
Oui, les enfants peuvent être plus sensibles aux effets toxiques des benzènesulfonates.
#3
Les personnes allergiques sont-elles plus à risque ?
Oui, les personnes ayant des antécédents d'allergies peuvent être plus susceptibles de réagir.
#4
L'environnement peut-il influencer le risque d'exposition ?
Oui, vivre près d'industries utilisant ces composés augmente le risque d'exposition.
#5
Les habitudes de travail influencent-elles le risque ?
Oui, des pratiques de travail non sécurisées augmentent le risque d'exposition aux benzènesulfonates.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 21/04/2025
Contenu vérifié selon les dernières recommandations médicales
Sous-catégories
4 au total
└─
Dobésilate de calcium
Calcium DobesilateD002123 -
D02.886.645.600.080.050.100.075
└─
4-Chloromercurio-benzènesulfonate
4-ChloromercuribenzenesulfonateD002731 -
D02.886.645.600.080.050.100.100
└─
1,2-Dihydroxy-benzène-3,5-disulfonate de disodium
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltD014013 -
D02.886.645.600.080.050.100.150
└─
Étamsylate
EthamsylateD004979 -
D02.886.645.600.080.050.100.300
Auteurs principaux
Atziri Corin Chavez Alvarez
8 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe oncologie, Québec, QC, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec QC G1V 0A6, Canada; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, 2725 chemin Ste-Foy, Québec QC G1V 4G5, Canada.
Publications dans "Benzènesulfonates" :
-
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bioorganic chemistry 2024-03-20
-
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.
Chemical biology & drug design 2021-10-17
-
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Bioorganic & medicinal chemistry letters 2024-04-11
-
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.
RSC medicinal chemistry 2024-08-27
-
Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
European journal of medicinal chemistry 2021-01-06
Sébastien Fortin
8 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe oncologie, Québec, QC, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec QC G1V 0A6, Canada. Electronic address: sebastien.fortin@pha.ulaval.ca.
Publications dans "Benzènesulfonates" :
-
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bioorganic chemistry 2024-03-20
-
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.
Chemical biology & drug design 2021-10-17
-
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Bioorganic & medicinal chemistry letters 2024-04-11
-
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.
RSC medicinal chemistry 2024-08-27
-
Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
European journal of medicinal chemistry 2021-01-06
Chahrazed Bouzriba
7 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe oncologie, Québec, QC, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec QC G1V 0A6, Canada; These authors contributed equally to this work. Electronic address: chahrazed.bouzriba.1@ulaval.ca.
Publications dans "Benzènesulfonates" :
-
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bioorganic chemistry 2024-03-20
-
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.
Chemical biology & drug design 2021-10-17
-
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Bioorganic & medicinal chemistry letters 2024-04-11
-
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.
RSC medicinal chemistry 2024-08-27
-
Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
European journal of medicinal chemistry 2021-01-06
Mathieu Gagné-Boulet
5 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe oncologie, Québec, QC, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec QC G1V 0A6, Canada; These authors contributed equally to this work.
Publications dans "Benzènesulfonates" :
-
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bioorganic chemistry 2024-03-20
-
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.
Chemical biology & drug design 2021-10-17
-
Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
European journal of medicinal chemistry 2021-01-06
-
Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.
European journal of medicinal chemistry 2021-11-19
-
Evaluation of the time-dependent antiproliferative activity and liver microsome stability of 3 phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as promising CYP1A1-dependent antimicrotubule prodrugs.
The Journal of pharmacy and pharmacology 2019-11-14
Vincent Ouellette
5 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe oncologie, Québec, QC, Canada; Faculté de pharmacie, Université Laval, Pavillon Ferdinand-Vandry, 1050 avenue de la Médecine, Québec QC G1V 0A6, Canada.
Publications dans "Benzènesulfonates" :
-
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents.
Bioorganic chemistry 2024-03-20
-
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Bioorganic & medicinal chemistry letters 2024-04-11
-
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.
RSC medicinal chemistry 2024-08-27
-
Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.
European journal of medicinal chemistry 2021-11-19
-
Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.
Journal of medicinal chemistry 2023-02-13
René C-Gaudreault
3 publications dans cette catégorie
Affiliations :
- Centre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Hôpital Saint-François d'Assise, 10 Rue de l'Espinay, Québec, QC, G1L 3L5, Canada; Département de médecine moléculaire, Faculté de médecine, Université Laval, Québec, QC, G1V 0A6, Canada.
Publications dans "Benzènesulfonates" :
-
Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.
European journal of medicinal chemistry 2021-11-19
-
Evaluation of the time-dependent antiproliferative activity and liver microsome stability of 3 phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as promising CYP1A1-dependent antimicrotubule prodrugs.
The Journal of pharmacy and pharmacology 2019-11-14
-
Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.
Journal of medicinal chemistry 2023-02-13
Xuelian Zhou
2 publications dans cette catégorie
Affiliations :
- Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China; International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, China.
Publications dans "Benzènesulfonates" :
-
Benzenesulfonic acid-based hydrotropic system for achieving lignocellulose separation and utilization under mild conditions.
Bioresource technology 2021-06-04
-
Mechanistic insights into morphological and chemical changes during benzenesulfonic acid pretreatment and simultaneous saccharification and fermentation process for ethanol production.
Bioresource technology 2022-07-04
Hongqi Dai
2 publications dans cette catégorie
Affiliations :
- Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China; International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, China.
Publications dans "Benzènesulfonates" :
-
Benzenesulfonic acid-based hydrotropic system for achieving lignocellulose separation and utilization under mild conditions.
Bioresource technology 2021-06-04
-
Mechanistic insights into morphological and chemical changes during benzenesulfonic acid pretreatment and simultaneous saccharification and fermentation process for ethanol production.
Bioresource technology 2022-07-04
Javed Masood Khan
2 publications dans cette catégorie
Affiliations :
- King Saud University, Department of Food Science and Nutrition, Faculty of Food and Agricultural Sciences, 2460, Riyadh 11451, Saudi Arabia. Electronic address: jmkhan@ksu.edu.sa.
Publications dans "Benzènesulfonates" :
-
Deciphering the role of premicellar and micellar concentrations of sodium dodecyl benzenesulfonate surfactant in insulin fibrillation at pH 2.0.
International journal of biological macromolecules 2020-01-23
-
Different conformational states of hen egg white lysozyme formed by exposure to the surfactant of sodium dodecyl benzenesulfonate.
International journal of biological macromolecules 2019-01-22
Ajamaluddin Malik
2 publications dans cette catégorie
Affiliations :
- King Saud University, Department of Biochemistry, College of Science, Riyadh 11451, Saudi Arabia.
Publications dans "Benzènesulfonates" :
-
Deciphering the role of premicellar and micellar concentrations of sodium dodecyl benzenesulfonate surfactant in insulin fibrillation at pH 2.0.
International journal of biological macromolecules 2020-01-23
-
Different conformational states of hen egg white lysozyme formed by exposure to the surfactant of sodium dodecyl benzenesulfonate.
International journal of biological macromolecules 2019-01-22
Priyankar Sen
2 publications dans cette catégorie
Affiliations :
- Vellore Institute of Technology, Centre for Bioseparation Technology, Vellore 632014, India.
Publications dans "Benzènesulfonates" :
-
Deciphering the role of premicellar and micellar concentrations of sodium dodecyl benzenesulfonate surfactant in insulin fibrillation at pH 2.0.
International journal of biological macromolecules 2020-01-23
-
Different conformational states of hen egg white lysozyme formed by exposure to the surfactant of sodium dodecyl benzenesulfonate.
International journal of biological macromolecules 2019-01-22
Anwar Ahmed
2 publications dans cette catégorie
Affiliations :
- King Saud University, Department of Biochemistry, College of Science, Riyadh 11451, Saudi Arabia.
Publications dans "Benzènesulfonates" :
-
Deciphering the role of premicellar and micellar concentrations of sodium dodecyl benzenesulfonate surfactant in insulin fibrillation at pH 2.0.
International journal of biological macromolecules 2020-01-23
-
Different conformational states of hen egg white lysozyme formed by exposure to the surfactant of sodium dodecyl benzenesulfonate.
International journal of biological macromolecules 2019-01-22
Qiyu Wang
2 publications dans cette catégorie
Affiliations :
- School of Metallurgy and Environment, Hunan Province Key Laboratory of Nonferrous Value-Added Metallurgy, Central South University, Changsha 410083, Hunan, China; Engineering Research Centre of Advanced Battery Materials, The Ministry of Education, Changsha 410083, Huanan, China. Electronic address: wangqiyucsu@163.com.
Publications dans "Benzènesulfonates" :
-
Ammonium benzenesulfonate as an electrolyte additive to relieve the irreversible accumulation of lithium sulfide for high-energy density lithium-sulfur battery.
Journal of colloid and interface science 2022-08-27
-
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway.
Toxicology 2023-04-13
Geneviève Hamel-Côté
2 publications dans cette catégorie
Affiliations :
- Centre de recherche du CHU de Québec-Université Laval, Axe Oncologie, Hôpital Saint-François d'Assise, 10 rue de l'Espinay, Québec, QC G1L 3L5, Canada. Electronic address: genevieve.hamel-cote@crchudequebec.ulaval.ca.
Publications dans "Benzènesulfonates" :
-
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Bioorganic & medicinal chemistry letters 2024-04-11
-
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells.
RSC medicinal chemistry 2024-08-27
Marie-France Côté
2 publications dans cette catégorie
Affiliations :
- Centre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Hôpital Saint-François d'Assise, 10 Rue de l'Espinay, Québec, QC, G1L 3L5, Canada.
Publications dans "Benzènesulfonates" :
-
Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation.
European journal of medicinal chemistry 2021-11-19
-
Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.
Journal of medicinal chemistry 2023-02-13
Mitra Zarifi Khosroshahi
2 publications dans cette catégorie
Affiliations :
- Oncology Division, CHU de Québec-Université Laval Research Center, Hôpital Saint-François d'Assise, Quebec City, QC, Canada.
- Faculty of Pharmacy, Université Laval, Quebec City, QC, Canada.
Publications dans "Benzènesulfonates" :
-
Evaluation of the time-dependent antiproliferative activity and liver microsome stability of 3 phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as promising CYP1A1-dependent antimicrotubule prodrugs.
The Journal of pharmacy and pharmacology 2019-11-14
-
Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.
Journal of medicinal chemistry 2023-02-13
Shoniya Thomas
1 publication dans cette catégorie
Affiliations :
- School of Chemical Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India.
Publications dans "Benzènesulfonates" :
-
Sonochemical degradation of benzenesulfonic acid in aqueous medium.
Chemosphere 2020-03-13
Manoj P Rayaroth
1 publication dans cette catégorie
Affiliations :
- School of Environmental Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India.
Publications dans "Benzènesulfonates" :
-
Sonochemical degradation of benzenesulfonic acid in aqueous medium.
Chemosphere 2020-03-13
Sunil Paul M Menacherry
1 publication dans cette catégorie
Affiliations :
- School of Environmental Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India.
Publications dans "Benzènesulfonates" :
-
Sonochemical degradation of benzenesulfonic acid in aqueous medium.
Chemosphere 2020-03-13
Usha K Aravind
1 publication dans cette catégorie
Affiliations :
- School of Environmental Studies, Cochin University of Science and Technology (CUSAT), Kochi, 682022, India.
Publications dans "Benzènesulfonates" :
-
Sonochemical degradation of benzenesulfonic acid in aqueous medium.
Chemosphere 2020-03-13
Sources (10000 au total)
Evidence for objects of implementation in healthcare: considerations for Implementation Science and Implementation Science Communications.
The journals Implementation Science and Implementation Science Communications are focused on the implementation of evidence into healthcare practice and policy. This editorial offers reflections on ho...
Revisiting the scope and expectations of Implementation Science and Implementation Science Communications.
This editorial updates the scope and submission expectations of Implementation Science and Implementation Science Communications. We refine our protocol publishing policies and set out new expectation...
Advancing environmental health sciences through implementation science.
Environmental health sciences have identified and characterized a range of environmental exposures and their associated risk for disease, as well as informed the development of interventions, includin... Numerous studies have documented the enormous time lag between research and practice, noting that dissemination and implementation are not passive processes but rely on active and intentional strategi... Environmental health researchers are well positioned to advance health promotion and disease prevention by incorporating implementation science into their work. This article describes the rationale fo...
Making implementation science more real.
Implementation science in healthcare aims to understand how to get evidence into practice. Once this is achieved in one setting, it becomes increasingly difficult to replicate elsewhere. The problem i...
Using Implementation Science in Nursing Research.
Clinical research continues to build knowledge that can potentially improve clinical and health service outcomes; however, integrating evidence into routine care is challenging, resulting in a knowled... A narrative synthesis of the implementation science literature was conducted. A series of case studies were purposively selected to demonstrate the application of commonly used implementation theories... Implementation science theoretical approaches have been used by nurses and multidisciplinary teams to better understand the gap between knowledge and practice for better informed implementation. These... By using implementation science research practice, nurses can also build a strong foundation of evidence about nursing clinical practice. As an approach, implementation science is practical and can op...
Implementation science for quality improvement in pediatric surgery.
Despite the widespread integration of quality improvement principles into pediatric surgical practice, the actual adoption of evidence-based practices continues to be a challenge. The field of pediatr...
Implementation science: why should we care?
There is a 17-year gap between the publication of research which proves an intervention is efficacious and effective and the implementation of that same intervention into practice [1]. In behavioral h...
What is the role of randomised trials in implementation science?
There is a consistent demand for implementation science to inform global efforts to close the gap between evidence and practice. Key evaluation questions for any given implementation strategy concern ... There is a continuing debate about the primacy of the place of randomised trials in evaluating implementation strategies, especially given the evolution of more rigorous quasi-experimental designs. Fu... Policy-makers and researchers should avoid prematurely discarding trial designs when evaluating implementation strategies and work to enhance the conditions for their conduct....
Implementation science in nursing education research: An exemplar.
Using evidence-based teaching approaches can improve nursing students' learning. However, variation in how - or if - these approaches are implemented by faculty and nursing educators is prevalent. A t... The purpose of this project was to use an implementation science framework to implement and evaluate the quality of a doctor of nursing practice (DNP) course before and after implementing evidence-bas... A pre/post design was used to evaluate course outcomes following implementation of evidence-based teaching approaches.... A small, private university in the southeastern United States.... Students who enrolled in a DNP healthcare quality improvement course.... An implementation science framework for integrating evidence-based teaching approaches was used to guide this project. Revisions were made to a DNP course, with evidence-based teaching approaches impl... After using the implementation science framework to translate evidence-based teaching approaches, there was a statistically significant improvement in three course evaluation questions and the overall... Using a structured implementation science framework and plan to translate and evaluate evidence-based teaching approaches resulted in significant improvements in course outcomes. Nurse educators shoul...