Titre : Benzocycloheptènes

Benzocycloheptènes : Questions médicales fréquentes

Termes MeSH sélectionnés :

MEDLINE

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment identifier les benzocycloheptènes ?

L'identification se fait par des techniques de spectroscopie et de chromatographie.
Spectroscopie Chromatographie
#2

Quels tests sont utilisés pour les benzocycloheptènes ?

Des tests de toxicité et d'efficacité sont réalisés en laboratoire.
Tests de toxicité Efficacité
#3

Les benzocycloheptènes sont-ils détectables dans le sang ?

Oui, ils peuvent être détectés par des analyses spécifiques dans des échantillons biologiques.
Analyse sanguine Échantillons biologiques
#4

Y a-t-il des marqueurs spécifiques pour ces composés ?

Des marqueurs biologiques peuvent indiquer l'exposition à ces composés.
Marqueurs biologiques Exposition
#5

Peut-on utiliser l'imagerie pour les benzocycloheptènes ?

L'imagerie moléculaire peut aider à visualiser leur distribution dans les tissus.
Imagerie moléculaire Distribution tissulaire

Symptômes 5

#1

Quels sont les effets secondaires des benzocycloheptènes ?

Ils peuvent provoquer des nausées, des vertiges ou des réactions allergiques.
Effets secondaires Réactions allergiques
#2

Les benzocycloheptènes causent-ils des douleurs ?

Des douleurs peuvent survenir en cas de toxicité ou d'allergie.
Douleurs Toxicité
#3

Y a-t-il des symptômes neurologiques associés ?

Oui, des symptômes comme des maux de tête ou des troubles de la coordination peuvent apparaître.
Symptômes neurologiques Troubles de la coordination
#4

Peut-on observer des symptômes cutanés ?

Des éruptions cutanées peuvent survenir en cas de réaction allergique.
Éruptions cutanées Réaction allergique
#5

Les benzocycloheptènes affectent-ils le système respiratoire ?

Une exposition excessive peut entraîner des irritations respiratoires.
Système respiratoire Irritations

Prévention 5

#1

Comment prévenir l'exposition aux benzocycloheptènes ?

Utiliser des équipements de protection et suivre les protocoles de sécurité en laboratoire.
Équipements de protection Protocoles de sécurité
#2

Y a-t-il des formations pour manipuler ces composés ?

Oui, des formations spécifiques sont souvent requises pour les chercheurs.
Formations Manipulation
#3

Quels sont les risques en milieu industriel ?

Les travailleurs peuvent être exposés à des niveaux élevés sans protection adéquate.
Milieu industriel Exposition
#4

Des réglementations existent-elles pour leur usage ?

Oui, des réglementations strictes encadrent leur utilisation en laboratoire et en industrie.
Réglementations Usage industriel
#5

Comment évaluer les risques d'exposition ?

Des évaluations de risque doivent être effectuées régulièrement dans les environnements de travail.
Évaluation des risques Environnements de travail

Traitements 5

#1

Comment traiter une intoxication aux benzocycloheptènes ?

Le traitement inclut l'élimination de l'exposition et des soins symptomatiques.
Intoxication Soins symptomatiques
#2

Y a-t-il des antidotes pour ces composés ?

Actuellement, il n'existe pas d'antidote spécifique pour les benzocycloheptènes.
Antidotes Composés chimiques
#3

Quels médicaments peuvent aider en cas d'allergie ?

Des antihistaminiques peuvent être utilisés pour traiter les réactions allergiques.
Antihistaminiques Réactions allergiques
#4

Les benzocycloheptènes nécessitent-ils une hospitalisation ?

Une hospitalisation peut être nécessaire en cas de symptômes graves.
Hospitalisation Symptômes graves
#5

Comment gérer les effets à long terme ?

Un suivi médical régulier est recommandé pour surveiller les effets à long terme.
Suivi médical Effets à long terme

Complications 5

#1

Quelles complications peuvent survenir avec ces composés ?

Des complications comme des lésions organiques peuvent survenir en cas d'exposition prolongée.
Complications Lésions organiques
#2

Les benzocycloheptènes peuvent-ils causer des cancers ?

Des études suggèrent un potentiel cancérigène, mais des recherches supplémentaires sont nécessaires.
Cancers Potentiel cancérigène
#3

Y a-t-il des effets sur la reproduction ?

Des effets néfastes sur la reproduction ont été observés dans certaines études animales.
Effets sur la reproduction Études animales
#4

Peut-on développer des allergies à long terme ?

Oui, des sensibilisations peuvent se développer avec une exposition répétée.
Allergies Sensibilisations
#5

Les benzocycloheptènes affectent-ils le système immunitaire ?

Une exposition prolongée peut altérer la fonction immunitaire, augmentant les infections.
Système immunitaire Infections

Facteurs de risque 5

#1

Qui est le plus à risque d'exposition ?

Les travailleurs en laboratoire et en industrie chimique sont les plus exposés.
Travailleurs Industrie chimique
#2

L'âge influence-t-il la sensibilité ?

Oui, les jeunes et les personnes âgées peuvent être plus sensibles aux effets toxiques.
Âge Sensibilité
#3

Y a-t-il des prédispositions génétiques ?

Certaines prédispositions génétiques peuvent augmenter la sensibilité aux toxines.
Prédispositions génétiques Sensibilité aux toxines
#4

Les antécédents médicaux jouent-ils un rôle ?

Oui, des antécédents d'allergies ou de maladies respiratoires augmentent le risque.
Antécédents médicaux Allergies
#5

L'environnement de travail influence-t-il le risque ?

Oui, un environnement de travail mal ventilé augmente le risque d'exposition.
Environnement de travail Ventilation
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 08/03/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Jiatian Li

1 publication dans cette catégorie

Affiliations :
  • State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.

Xiangwen Tan

1 publication dans cette catégorie

Affiliations :
  • State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.

Huanfeng Jiang

1 publication dans cette catégorie

Affiliations :
  • State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.

Wanqing Wu

1 publication dans cette catégorie

Affiliations :
  • State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.

Sources (103 au total)

MEDLINE citation tool accuracy: an analysis in two platforms.

Libraries provide access to databases with auto-cite features embedded into the services; however, the accuracy of these auto-cite buttons is not very high in humanities and social sciences databases.... This case compares two biomedical databases, Ovid MEDLINE and PubMed, to see if either is reliable enough to confidently recommend to students for use when writing papers. A total of 60 citations were... Error rates were higher in Ovid MEDLINE than PubMed but neither database platform provided error-free references. The auto-cite tools were not reliable. Zero of the 60 citations examined were 100% cor...

Search strategies (filters) to identify systematic reviews in MEDLINE and Embase.

Bibliographic databases provide access to an international body of scientific literature in health and medical sciences. Systematic reviews are an important source of evidence for clinicians, research... To review systematically empirical studies that report the development, evaluation, or comparison of search filters to retrieve reports of systematic reviews in MEDLINE and Embase.... We searched the following databases from inception to January 2023: MEDLINE, Embase, PsycINFO; Library, Information Science & Technology Abstracts (LISTA) and Science Citation Index (Web of Science).... We included studies if one of their primary objectives is the development, evaluation, or comparison of a search filter that could be used to retrieve systematic reviews on MEDLINE, Embase, or both.... Two review authors independently extracted data using a pre-specified and piloted data extraction form using InterTASC Information Specialist Subgroup (ISSG) Search Filter Evaluation Checklist.... We identified eight studies that developed filters for MEDLINE and three studies that developed filters for Embase. Most studies are very old and some were limited to systematic reviews in specific cl... Studies reporting the development, evaluation, or comparison of search filters to retrieve reports of systematic reviews in MEDLINE showed similar sensitivity and precision, with one filter showing hi...

Network analysis for estimating standardization trends in genomics using MEDLINE.

Biotechnology in genomics, such as sequencing devices and gene quantification software, has proliferated and been applied to clinical settings. However, the lack of standards applicable to it poses pr... Of 16,538 articles retrieved from PubMed, published from 1975 to 2020, using search keywords "genomics and standard" and "clinical genomic sequence and standard", terms were extracted from the abstrac... Our research trend showed an increasing trend from 2003, years marked by the completion of the human genome project (2003). The content analysis showed that keywords related to such concepts as gene t... Through comprehensive trend analysis from our study, we provided the trend shifts and high-demand items in standardization for clinical genetics....

Suitability of indexing terms in the MEDLINE bibliographic database on drug-related problems.

For years, there has been controversy about the meaning of medication-related problems (MRPs). This has led several authors to attempt to redefine and classify this term with the aim of using it corre... To describe and analyze the appropriateness of the existing indexing of scientific publications in the MEDLINE bibliographical database with respect to drug-related problems (DRPs) and to determine wh... A descriptive study was conducted, using the following search terms: Medication Errors; Drug Interactions; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Contraindications, Drug. The ... The 1930 records analyzed showed a total of 2888 different major topics. These major topics were present, with at least one of the five descriptors studied, in 482 (25.0%; 95% CI 23.0-27.0) documentar... There was a very good direct exponential trend of the overall scientific output retrieved with the terms associated with DRPs, although the progression of the five descriptors separately did not show ...

Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE.

Cluster randomized trials (CRTs) are becoming an increasingly important design. However, authors of CRTs do not always adhere to requirements to explicitly identify the design as cluster randomized in... We trained, internally validated, and externally validated two convolutional neural networks and one support vector machine (SVM) algorithm to predict whether a citation is a CRT report or not. We exc... In internal validation, the ensemble algorithm discriminated best for identifying CRT reports with an AUC of 98.6% (95% confidence interval: 97.8%, 99.4%), sensitivity of 97.7% (94.3%, 100%), and spec... We successfully developed high-performance algorithms that identified whether a citation was a CRT report with high sensitivity and moderately high specificity. We provide open-source software to faci...

Development and validation of paired MEDLINE and Embase search filters for cost-utility studies.

Search filters are standardised sets of search terms, with validated performance, that are designed to retrieve studies with specific characteristics. A cost-utility analysis (CUA) is the preferred ty... We developed search filters to retrieve CUAs from MEDLINE and Embase. Our aim was to achieve recall of 90% or better across both databases while reducing the overall yield compared with our existing b... All 3 filter-pairs exceeded our target recall and led to substantial improvements in search proxy-precision. Our paired 'sensitive' filters achieved 100% recall (95% CI 99.0 to 100%) in the validation... Each of the 3 paired cost-utility filters enable the identification of almost all CUAs from MEDLINE and Embase from the validation set, with substantial savings in screening workload compared to our p...

The NICE search filters for treating and managing COVID-19: validation in MEDLINE and Embase (Ovid).

In this paper we report how the United Kingdom's National Institute for Health and Care Excellence (NICE) search filters for treating and managing COVID-19 were validated for use in MEDLINE (Ovid) and... We did two tests of recall to finalize the draft search filters. We updated the data from an earlier peer-reviewed publication for the first recall test. For the second test, we collated a set of syst... In the first recall test, both filters had 99.5% recall. In the second test, recall was 99.7% and 99.8% in MEDLINE and Embase respectively. Precision was 91.1% in a deduplicated sample of records. In ... We have validated search filters to identify records on treating and managing COVID-19. The filters may require subsequent updates, if new SARS-CoV-2 variants of concern or interest are discussed in f...

Updated generic search filters for finding studies of adverse drug effects in Ovid medline and Embase may retrieve up to 90% of relevant studies.

The most current objectively derived search filters for adverse drug effects are 15 years old and other strategies have not been developed and tested empirically.... To develop and validate search filters to retrieve evidence on adverse drug effects from Ovid medline and Ovid Embase.... We identified systematic reviews of adverse drug effects in Epistemonikos. From these reviews, we collated their included studies which we then randomly divided into three tests and one validation set... Of 107 systematic reviews which met our inclusion criteria, 1948 unique included studies were available from medline and 1980 from Embase. Generic adverse drug effects searches in medline and Embase a... We have derived and validated search filters that retrieve around 90% of records with adverse drug effects data in medline and Embase. The addition of specific adverse effects terms is required to ach...

Application of text mining to the development and validation of a geographic search filter to facilitate evidence retrieval in Ovid MEDLINE: An example from the United States.

Given the increasing volume of published research in bibliographic databases, efficient retrieval of evidence is crucial and represents an opportunity to integrate novel techniques such as text mining... To develop and validate a geographic search filter for identifying research from the United States (US) in Ovid MEDLINE.... US and non-US citations were collected from bibliographies of evidence-based reviews. Citations were partitioned by US/non-US status and randomly divided to a training and testing set. Using text mini... Common US-related terms included (as ratio of frequency in US/non-US citations) US populations and geographic terms [e.g., 'Americans' (15.5), 'Baltimore' (20.0)]. Common non-US terms were non-US geog... This search filter will streamline the identification of evidence from the US. Periodic updates may be necessary to reflect changes in MEDLINE's controlled vocabulary.... Text mining was instrumental to the development of this search filter. A novel technique generated a gold standard set comprising >20,000 citations. This method may be adapted to develop subsequent ge...