Comment diagnostiquer une dépendance aux benzodiazépines ?

Le diagnostic repose sur l'évaluation des symptômes et l'historique d'utilisation des médicaments.

Quels tests sont utilisés pour évaluer l'usage des benzodiazépines ?

Des tests de dépistage de drogues et des évaluations psychologiques peuvent être utilisés.

Quels critères DSM sont utilisés pour le diagnostic ?

Les critères DSM-5 incluent l'usage excessif et les symptômes de sevrage.

Comment évaluer l'efficacité d'un traitement par benzodiazépines ?

L'efficacité est évaluée par la réduction des symptômes d'anxiété ou d'insomnie.

Quels signes indiquent une surdose de benzodiazépines ?

Les signes incluent confusion, somnolence excessive et difficultés respiratoires.

Quels sont les effets secondaires courants des benzodiazépines ?

Les effets secondaires incluent somnolence, vertiges et troubles de la mémoire.

Comment reconnaître une réaction allergique aux benzodiazépines ?

Les réactions allergiques peuvent se manifester par éruptions cutanées et démangeaisons.

Quels symptômes indiquent un sevrage des benzodiazépines ?

Les symptômes de sevrage incluent anxiété, insomnie et tremblements.

Les benzodiazépines provoquent-elles des troubles cognitifs ?

Oui, elles peuvent entraîner des troubles de la mémoire et de la concentration.

Quels symptômes peuvent nécessiter une consultation médicale urgente ?

Des symptômes comme confusion sévère ou difficultés respiratoires nécessitent une urgence.

Comment prévenir la dépendance aux benzodiazépines ?

La prévention inclut une prescription prudente et une éducation sur les risques.

Quels conseils donner aux patients sur l'utilisation des benzodiazépines ?

Les patients doivent être informés des risques et de l'importance de suivre les prescriptions.

Comment surveiller l'utilisation des benzodiazépines ?

Les médecins doivent effectuer des suivis réguliers pour évaluer l'usage et les effets.

Quelles stratégies non médicamenteuses peuvent aider ?

Des techniques comme la méditation et l'exercice physique peuvent réduire l'anxiété.

Comment sensibiliser sur les risques des benzodiazépines ?

Des campagnes d'information et des ateliers peuvent sensibiliser le public aux risques.

Comment traiter une dépendance aux benzodiazépines ?

Le traitement inclut une désintoxication supervisée et une thérapie comportementale.

Quelles alternatives existent aux benzodiazépines pour l'anxiété ?

Les alternatives incluent les antidépresseurs et les thérapies cognitivo-comportementales.

Comment réduire progressivement l'utilisation des benzodiazépines ?

La réduction doit être progressive, sous supervision médicale pour éviter le sevrage.

Quels médicaments peuvent aider à gérer le sevrage ?

Des médicaments comme le diazépam peuvent être utilisés pour atténuer les symptômes de sevrage.

Quelle est la durée recommandée pour l'utilisation des benzodiazépines ?

L'utilisation est généralement recommandée pour une courte durée, souvent moins de 4 semaines.

Quelles complications peuvent survenir avec l'usage prolongé ?

L'usage prolongé peut entraîner des troubles cognitifs et une dépendance sévère.

Comment les benzodiazépines affectent-elles la santé mentale ?

Elles peuvent aggraver des troubles mentaux comme la dépression et l'anxiété.

Quels risques sont associés à l'association avec d'autres médicaments ?

L'association avec des opioïdes ou l'alcool augmente le risque de dépression respiratoire.

Les benzodiazépines peuvent-elles provoquer des chutes chez les personnes âgées ?

Oui, elles augmentent le risque de chutes et de fractures chez les personnes âgées.

Quels effets à long terme sur la mémoire sont observés ?

L'usage prolongé peut entraîner des troubles de la mémoire et des difficultés d'apprentissage.

Quels facteurs augmentent le risque de dépendance ?

Les antécédents de troubles mentaux et l'usage prolongé augmentent le risque de dépendance.

Comment l'âge influence-t-il l'usage des benzodiazépines ?

Les personnes âgées sont plus susceptibles de subir des effets secondaires et des complications.

Quel rôle joue l'environnement social dans l'usage ?

Un environnement stressant ou un manque de soutien social peut augmenter l'usage des benzodiazépines.

Les antécédents familiaux influencent-ils l'usage ?

Oui, des antécédents familiaux de dépendance peuvent augmenter le risque d'usage problématique.

Comment les troubles de santé mentale affectent-ils l'usage ?

Les personnes avec des troubles de santé mentale sont plus susceptibles d'utiliser des benzodiazépines.

Benzodiazépines - Informations médicales vérifiées

Developing a fall prevention intervention economic model.

2023

DOI: 10.1371/journal.pone.0280572 PMID: 36706109

Model-based economic evaluations require conceptualization of the model structure. Our objectives were to identify important health states, events, and patient attributes to be included in a model-bas... An expert panel comprising clinicians, health service researchers, health economists, a patient partner, and policy makers completed two rounds of online surveys to gain consensus on health states, ev... In total, 11 experts rated 24 health states/events and 41 patient attributes. Consensus was achieved on 14 health states/events and 26 patient characteristics. The proposed model structure incorporate... There is a dearth of studies presenting the model conceptualization process; consequently, this study involving multiple end user partners with opportunities for input at several stages adds to the li...

Humans Aged Cost-Benefit Analysis Consensus Models, Economic

Construction and application of economic resilience evaluation model for megacities.

2024

DOI: 10.1371/journal.pone.0301840 PMID: 38787848

Economic resilience provides a new perspective for megacities to achieve sustainable development when facing multiple shocks, and its accurate evaluation is an essential prerequisite for optimizing ur...

Cities Humans Models, Economic China Sustainable Development

Assessing economic investment required to scale up bariatric surgery capacity in England: a health economic modelling analysis.

31 Jul 2024

DOI: 10.1136/bmjopen-2024-084356 PMID: 39089720

To quantify the economic investment required to increase bariatric surgery (BaS) capacity in National Health Service (NHS) England considering the growing obesity prevalence and low provision of BaS i... Data were included for the patients with obesity who were eligible for BaS. We used a decision-tree approach including four distinct steps of the patient pathway to capture all associated resource use... BaS centres based in NHS and private sector hospitals in England.... Number of BaS procedures (including revision surgery), cost (GBP) and resource utilisation over 20 years.... At current capacity, the number of BaS procedures and the total cost over 20 years were estimated to be 140 220 and £1.4 billion, respectively. For strategy 1, these values were projected to increase ... The expansion of BaS capacity in England beyond a small proportion of the eligible population will likely be challenging given the significant upfront economic investment and additional requirement of...

Humans England Bariatric Surgery State Medicine Models, Economic +3 autres

Design and testing of a health economic Markov model for treatment of anorexia nervosa.

Dec 2022

DOI: 10.1080/14737167.2022.2119130 PMID: 36047856

Anorexia Nervosa (AN) is a severe psychiatric disorder and knowledge about the cost-effectiveness of potential interventions is limited. The aim of this paper is to introduce the... AnoMod-TI is a state-transition cohort simulation (Markov) model developed from a Dutch societal perspective, which consists of four health states - namely full remission (FR), partial remission (PR),... For the purpose of demonstrating AnoMod-TI and how it could be used to estimate cost-effectiveness over a 20-year time horizon, it was applied to a hypothetical treatment scenario. Results illustrate ... AnoMod-TI can be used to examine long-term cost-effectiveness of various interventions aimed at either treating AN or preventing relapse from a state of partial or full remission. AnoMod-TI is freely ...

Adult Adolescent Humans Anorexia Nervosa Models, Economic +4 autres

Examining the correlation between treatment effects in clinical trials and economic modeling.

Oct 2022

DOI: 10.1080/14737167.2022.2079497 PMID: 35582876

Many diseases have a sequential treatment pathway. Compared with patients without previous treatment, patients who fail initial treatment may have lower success rates with a second treatment. This phe... We developed a statistical model of covariance for the underlying unobserved correlation between treatments and established a mathematical expression for the magnitude of the latent correlation term. ... Our simulation study confirmed that a treatment correlation reduces the probability of success for the second treatment, compared with no correlation. We found that treatment correlations may be obser... We evaluated the correlation between treatment effects and our approach can be applied to clinical trial design and economic modeling of sequential clinical treatment pathways....

Clinical Trials as Topic Cost-Benefit Analysis Humans Models, Economic Models, Statistical

Data needs for integrated economic-epidemiological models of pandemic mitigation policies.

12 2022

DOI: 10.1016/j.epidem.2022.100644 PMID: 36375311

The COVID-19 pandemic and the mitigation policies implemented in response to it have resulted in economic losses worldwide. Attempts to understand the relationship between economics and epidemiology h...

Humans Pandemics COVID-19 Epidemiological Models Models, Economic +1 autres

Projecting overall survival in health-economic models: uncertainty and maturity of data.

03 2023

DOI: 10.1080/03007995.2023.2167442 PMID: 36628431

As lifetime horizons are considered for economic evaluations, the Kaplan-Meier (KM) estimate is used to extrapolate survival in cases of immature overall survival (OS) data. This study estimated the e... Fifteen phase 3 trials reporting KM estimates of OS where at least 70% maturity (i.e. 70% of the population had died during follow-up) were included and compared to artificially created truncated data... The Weibull (33%), log-logistic (32%) and log-normal (27%) were most often selected as the best fitting distribution. Compared to LM at full maturity, LM was overestimated in 23 and 40% of cases, at 3... The extent of OS maturity increases the risk of error when projecting long-term life expectancy for economic models. Even marginal gains in OS maturity result in more accurate estimations and should b...

Humans Survival Analysis Uncertainty Bayes Theorem Kaplan-Meier Estimate +1 autres

An Economic Model for Estimating Trial Costs with an Application to Placebo Surgery Trials.

03 2023

DOI: 10.1007/s40258-022-00775-4 PMID: 36575335

Waste in clinical trials remains rife. We developed an economic model to predict the cost of trials based on input costs, duration, power, number of sites, recruitment eligibility and consenting rates... We parameterised the model for three proxy placebo-controlled surgical trials using data from a systematic review, a bespoke cost survey, and from the literature. We used the model to compare target a... Successful trials more accurately anticipated the true recruitment rate that they achieved and those that overestimated this were most likely to fail. The costs of overestimating recruitment rates wer... This model shows the trade-offs between time and cost, or both, when recruitment is lower than anticipated. Greater consideration is needed to improve trial planning, reviewing, and funding of these t...

Humans Budgets Models, Economic Cost-Benefit Analysis

Patient and Public Involvement in Health Economics Modelling Raises the Need for Normative Guidance.

07 2023

DOI: 10.1007/s40273-023-01274-7 PMID: 37106229

Patient and public involvement in health economics research and health technology assessment has been increasing for some time; however, patient and public involvement in health economics modelling is...

Economics, Medical Models, Economic

Costs and models used in the economic analysis of Total Knee Replacement (TKR): A systematic review.

2023

DOI: 10.1371/journal.pone.0280371 PMID: 37490490

The main objective of this review is to summarize the evidence on the core modelling specifications and methodology on the cost-effectiveness of TKR compared to non-surgical management. Another object... The electronic databases used for this review were MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), HTAIn repository, Cost effectiveness Analysis (CEA) registry, and Google ... Thirty-two studies were included in this review, out of which eight studies used Markov model, five used regression model, one each reported Marginal structure model, discrete simulation model, decisi... The findings of this review showed that the Markov model was most widely used in the analysis of the cost effectiveness of TKR. Our review also concluded that the cost of TKR was higher in the develop...

Humans Arthroplasty, Replacement, Knee Cost-Benefit Analysis Cost-Effectiveness Analysis Osteoarthritis +3 autres

Benzodiazépines : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Alprazolam

Benzodiazépinones

Chlordiazépoxyde

Clobazam

Clorazépate dipotassique

Estazolam

Médazépam

Midazolam

Olanzapine

Triazolam

Bromazépam

Clonazépam

Dévazépide

Diazépam

Flumazénil

Flunitrazépam

Flurazépam

Lorazépam

Nitrazépam

Oxazépam

Pirenzépine

Prazépam

Témazépam

Nordazépam

Auteurs principaux

Sources (10000 au total)