Comment diagnostiquer une acidose métabolique ?

Un diagnostic se fait par analyse des gaz du sang et des tests biochimiques.

Quels tests pour détecter des acides carboxyliques ?

Des tests chromatographiques comme la chromatographie en phase gazeuse sont utilisés.

Quels symptômes indiquent une intoxication ?

Des symptômes comme des nausées, vomissements et troubles neurologiques peuvent apparaître.

Comment évaluer l'exposition aux acides ?

L'évaluation se fait par des tests sanguins et urinaires pour mesurer les niveaux d'acides.

Quels marqueurs biologiques sont pertinents ?

Les niveaux de lactate et d'acide pyruvique sont des marqueurs importants à surveiller.

Quels sont les symptômes d'une acidose ?

Les symptômes incluent fatigue, confusion, respiration rapide et maux de tête.

Comment se manifeste une intoxication par acides ?

Elle se manifeste par des brûlures, des douleurs abdominales et des troubles respiratoires.

Quels signes indiquent une acidémie ?

Des signes comme une respiration profonde et des troubles de la conscience peuvent survenir.

Quels symptômes sont liés à l'acide acétique ?

L'exposition à l'acide acétique peut causer irritation des yeux, de la peau et des voies respiratoires.

Quels symptômes d'une surconsommation d'acides ?

Des douleurs abdominales, des nausées et des vomissements peuvent survenir.

Comment prévenir l'exposition aux acides ?

Utiliser des équipements de protection et suivre les protocoles de sécurité en laboratoire.

Quelles mesures pour éviter l'acidose ?

Maintenir une alimentation équilibrée et surveiller les maladies métaboliques.

Comment éviter les intoxications ?

Éviter le contact direct avec des produits chimiques et respecter les consignes de sécurité.

Quelles précautions en milieu industriel ?

Mettre en place des systèmes de ventilation et des formations pour les employés.

Comment prévenir les brûlures chimiques ?

Utiliser des gants et des lunettes de protection lors de la manipulation d'acides.

Quel traitement pour l'acidose métabolique ?

Le traitement peut inclure des bicarbonates de sodium et des soins de soutien.

Comment traiter une intoxication par acides ?

Le traitement consiste en des soins d'urgence, y compris la décontamination et l'hydratation.

Quels médicaments pour réduire l'acidité ?

Des antiacides et des inhibiteurs de la pompe à protons peuvent être prescrits.

Comment gérer les brûlures chimiques ?

Il faut rincer abondamment à l'eau et consulter un médecin pour évaluation.

Quel rôle des fluides intraveineux ?

Les fluides IV aident à corriger les déséquilibres électrolytiques et l'hydratation.

Quelles complications de l'acidose ?

Les complications incluent des troubles cardiaques, des convulsions et un coma.

Quels risques d'une intoxication prolongée ?

Une intoxication prolongée peut entraîner des lésions organiques et des troubles neurologiques.

Quelles complications des brûlures chimiques ?

Les complications peuvent inclure des infections et des cicatrices permanentes.

Quels effets à long terme de l'acidose ?

Des effets à long terme peuvent inclure des problèmes rénaux et des troubles métaboliques.

Quelles complications d'une surconsommation d'acides ?

Une surconsommation peut causer des ulcères gastriques et des hémorragies internes.

Quels facteurs de risque pour l'acidose ?

Les maladies chroniques comme le diabète et les maladies rénales augmentent le risque.

Qui est à risque d'intoxication par acides ?

Les travailleurs en milieu industriel et ceux manipulant des produits chimiques sont à risque.

Quels comportements augmentent le risque d'acidose ?

Une alimentation déséquilibrée et la déshydratation peuvent augmenter le risque.

Quels médicaments peuvent causer l'acidose ?

Certains diurétiques et médicaments anti-inflammatoires peuvent provoquer l'acidose.

Quels antécédents médicaux sont préoccupants ?

Des antécédents de maladies métaboliques ou rénales sont des facteurs de risque importants.

Acides carboxyliques - Informations médicales vérifiées

Topical diquafosol versus hyaluronic acid for the treatment of dry eye disease: a meta-analysis of randomized controlled trials.

Dec 2023

DOI: 10.1007/s00417-023-06083-4 PMID: 37162564

Diquafosol enhances fluid transfer and mucin secretion on ocular surface, which has been suggested as an effective treatment for dry eye disease (DED). The aim of the systematic review and meta-analys... Relevant randomized controlled trials were obtained via search of electronic including PubMed, Embase, Cochrane Library, and Web of Science. A random-effects model was used to pool the results after i... A total of nine RCTs involving 1295 patients with DED were included in the meta-analysis. Compared to treatment with 0.1% HA, topical treatment with 3% diquafosol significantly improved the Ocular Sur... Topical treatment with 3% diquafosol may be more effective than 0.1% HA for patients with DED. However, the long-term efficacy and tolerability of diquafosol still need to be determined....

Humans Hyaluronic Acid Ophthalmic Solutions Randomized Controlled Trials as Topic Dry Eye Syndromes +1 autres

The UPDATE trial (UVB Phototherapy in Dermatology for ATopic Eczema): study protocol for a randomized controlled trial of narrowband UVB with optimal topical therapy versus optimal topical therapy in patients with atopic eczema.

16 Jul 2024

DOI: 10.1186/s13063-024-08334-z PMID: 39014498

Narrowband ultraviolet B (NB-UVB) phototherapy is commonly prescribed for patients with moderate-to-severe atopic eczema (AE). The efficacy of NB-UVB, however, has not yet properly been established, a... A pragmatic, multicenter, PROBE trial will be performed with 1:1 randomization of 316 adult patients with moderate-to-severe AE who have inadequate disease control with topical therapy and who are eli... The UPDATE trial aims to provide high-quality evidence regarding the (cost-)effectiveness and safety of NB-UVB phototherapy in moderate-to-severe AE patients. Challenges that are addressed in the prot... ClinicalTrials.gov NCT05704205. Registered on December 8, 2022....

Humans Ultraviolet Therapy Dermatitis, Atopic Prospective Studies Multicenter Studies as Topic +11 autres

Design and Methodological Issues of Within-Person (Split-Body) Randomized Controlled Trials Evaluating a Topical Treatment: A Systematic Review.

2023

DOI: 10.1159/000530149 PMID: 36990057

Topical drugs are often used as first-line treatment for dermatological conditions. A within-person design may then be well adapted: it consists of randomizing lesions/body sites rather than patients,... The aim of this review was to provide a methodological overview of within-person randomized trials (WP-RCTs) in dermatology.... We searched for eligible trials published between 2017 and 2021 in MEDLINE, Embase, and Central in dermatology journals and the 6 highest-impact-factor general medical journals. Two authors selected p... From 1,034 articles identified, we included 54 WP-RCTs, mainly for acne vulgaris, psoriasis, actinic keratosis, and atopic dermatitis. In most of the trials, patients had only 2 lesions/body sites. In... Our systematic review highlights that despite the publication of the CONSORT checklist extension for WP-RCTs in 2017, this design is rarely used, and when it is, there are methodological and reporting...

Humans Randomized Controlled Trials as Topic Acne Vulgaris Dermatitis, Atopic Checklist

Laser and light therapy combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials.

17 Feb 2023

DOI: 10.1007/s10103-023-03734-0 PMID: 36800063

We aim to evaluate the clinical efficacy and safety of using laser and light combined with topical minoxidil for alopecia areata. We searched PubMed, Embase, Web of Science, the Cochrane Library, Chin...

Humans Minoxidil Alopecia Areata Randomized Controlled Trials as Topic Phototherapy +1 autres

Nd:YAG/Er:YAG dual laser vs. topical steroid to treat vulvar lichen sclerosus: study protocol of a randomized controlled trial.

08 2023

DOI: 10.1007/s00404-023-07055-z PMID: 37145134

Vulvar lichen sclerosus (LS) is a chronic debilitating inflammatory skin disease. Today, the gold standard is a life-long topical steroid treatment. Alternative options are highly desired. We present ... We recruited 66 patients, 44 in the laser arm and 22 in the steroid arm. Patients with a physician-administered clinical LS score ≥ 4 were included. Participants received either four laser treatments ... The findings of this trial have the potential to offer a novel treatment option for LS. The standardized Nd:YAG/Er:YAG laser settings and the treatment regime are presented in this paper.... NCT03926299....

Female Humans Vulvar Lichen Sclerosus Lasers, Solid-State Prospective Studies +4 autres

Efficacy and safety of compound glycyrrhizin combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials.

Dec 2024

DOI: 10.1080/09546634.2024.2381766 PMID: 39230160

Alopecia areata (AA) is a common autoimmune skin disease. Our study aimed to systematically evaluate the efficacy and safety of compound glycyrrhizin (CG) combined with topical minoxidil therapy in tr... We searched the PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases. Randomized controlled trials (RCTs) on CG combined with topical minoxidil therapy compared with topi... 11 RCTs and 1189 patients were included. Compared with topical minoxidil therapy alone, CG combined with topical minoxidil therapy was more effective at improving the clinical efficacy (RR = 1.36, 95%... The current evidence indicates that CG combined with topical minoxidil therapy is effective and safe for AA. However, owing to the suboptimal quality of the included studies, more high-quality and lar...

Humans Alopecia Areata Minoxidil Randomized Controlled Trials as Topic Drug Therapy, Combination +3 autres

Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

13 11 2022

DOI: 10.3390/ijerph192214921 PMID: 36429639

The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized con...

Humans Pressure Ulcer Olive Oil Randomized Controlled Trials as Topic Incidence +1 autres

Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials.

Dec 2022

DOI: 10.1080/17512433.2022.2134114 PMID: 36210241

To investigate the clinical efficacy and safety of topical difamilast in mild-to-moderate atopic dermatitis (AD).... Only randomized controlled trials (RCTs) that compared topical difamilast with vehicle treatment for patients with AD were included. PubMed, Web of Science, Ovid Medline, Cochrane Library, ClinicalTri... Five studies enrolling a total of 1009 patients with mild-to-moderate AD were identified. Compared with the topical vehicle, topical difamilast was associated with a significantly higher success rate ... This meta-analysis suggests that topical difamilast is an effective and safe treatment for mild-to-moderate AD....

Humans Dermatitis, Atopic Randomized Controlled Trials as Topic Treatment Outcome Eczema +2 autres

Effectiveness of laser and topical tranexamic acid combination therapy in melasma: An updated systematic review and meta-analysis of randomized controlled trials.

16 Jun 2023

DOI: 10.1007/s10103-023-03810-5 PMID: 37326860

Melasma is a chronic relapsing skin condition. Laser therapy is a new advancement in treatment. Whether the topical application of tranexamic acid (TXA) increases the efficacy of laser therapy in mela...

Humans Tranexamic Acid Carbon Dioxide Randomized Controlled Trials as Topic Lasers, Gas +2 autres

Randomized controlled trials of biomarker targets.

02 2023

DOI: 10.1177/17407745221131820 PMID: 36373783

Randomized controlled trials are used to estimate the causal effect of a treatment on a health outcome of interest in a patient population. Often the specified treatment in a randomized controlled tri... We use causal reasoning to explain why randomized controlled trials of biomarker targets can arrive at conflicting or misleading conclusions. We describe four key threats to the validity of trials of ... We illustrate these findings using evidence from 15 randomized controlled trials of blood pressure targets for management of hypertension. Randomized trials of blood pressure targets exhibit substanti... Researchers should critically assess meta-analyses of trials of targets for variation in the types, distributions, and off-target effects of therapies studied. Trial investigators should release detai...

Humans Randomized Controlled Trials as Topic Hypertension Blood Pressure Biomarkers

Acides carboxyliques : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Acides acycliques

Acides aldéhydiques

Acides carbocycliques

Esters

Hydroxyacides

Cétoacides

Acétamides

Anhydrides acétiques

Acide aminooxy-acétique

Acide édétique

Acide egtazique

Acide nitrilo-triacétique

Acide pentétique

Acide peracétique

Acrylamides

Méthacrylates

Aldicarb

Carisoprodol

Méprobamate

Phényl-carbamates

Uréthane

Adipates

Acide bongkrékique

Fumarates

Glutarates

Maléates

Malonates

Oxalates

Acides piméliques

Succinates

Formamides

Esters d'acide formique

Dextropropoxyphène

Lévopropoxyphène

Nafénopine

Acide aconitique

Citrates

Proadifène

Acides caféiques

Cinansérine

Acides coumariques

Acide aurintricarboxylique

Acide chlorogénique

Tilidine

Acide tranéxamique

Cyclopentolate

Diclofenac

Acide 3,4-dihydroxy-benzèneacétique

Acides diphénylacétiques

Guanfacine

Acide homogentisique

Acide homovanillique

Propanidide

Fénoprofène

Ibuprofène

Kétoprofène

Suprofène

Phtalate de dibutyle

Phtalate de bis[2-éthylhexyle]

Phtalaldéhyde

Anhydrides phtaliques

Bénactyzine

Halofénate

Méclofénoxate

Phénoxy-acétates

Déferoxamine

Vorinostat

Oxybate de sodium

Acide lactique