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"name": "La dystonie affecte-t-elle la parole ?",
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"text": "Non, les symptômes peuvent varier en intensité et peuvent être exacerbés par le stress."
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"name": "La dystonie peut-elle causer de la douleur ?",
"position": 9,
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"text": "Oui, les contractions musculaires peuvent entraîner des douleurs et de l'inconfort."
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"name": "Y a-t-il des types spécifiques de dystonie ?",
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"text": "Oui, il existe plusieurs types, comme la dystonie focale et la dystonie généralisée."
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"text": "Il n'existe pas de méthode de prévention garantie, mais un mode de vie sain peut aider."
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"name": "Le stress influence-t-il la dystonie ?",
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"text": "Oui, le stress peut aggraver les symptômes de la dystonie, donc la gestion du stress est importante."
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"position": 14,
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"text": "Éviter les toxines environnementales et les traumatismes peut réduire le risque de dystonie."
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"@type": "Question",
"name": "L'éducation sur la dystonie est-elle utile ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, une meilleure compréhension de la maladie peut aider les patients à gérer leurs symptômes."
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"position": 16,
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"text": "Les traitements incluent des médicaments, des thérapies physiques et parfois la chirurgie."
}
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{
"@type": "Question",
"name": "Les médicaments sont-ils efficaces pour la dystonie ?",
"position": 17,
"acceptedAnswer": {
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"text": "Oui, des médicaments comme les anticholinergiques peuvent réduire les symptômes chez certains patients."
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"@type": "Question",
"name": "La toxine botulique est-elle utilisée pour la dystonie ?",
"position": 18,
"acceptedAnswer": {
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"text": "Oui, les injections de toxine botulique peuvent aider à réduire les spasmes musculaires."
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"name": "La thérapie physique aide-t-elle la dystonie ?",
"position": 19,
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"text": "Oui, la thérapie physique peut améliorer la mobilité et réduire la douleur associée."
}
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"@type": "Question",
"name": "Quand la chirurgie est-elle envisagée pour la dystonie ?",
"position": 20,
"acceptedAnswer": {
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"text": "La chirurgie est envisagée lorsque les traitements médicamenteux échouent à soulager les symptômes."
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"@type": "Question",
"name": "Quelles complications peuvent survenir avec la dystonie ?",
"position": 21,
"acceptedAnswer": {
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"text": "Les complications incluent des douleurs chroniques, des troubles de la posture et des difficultés fonctionnelles."
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"@type": "Question",
"name": "La dystonie peut-elle affecter la qualité de vie ?",
"position": 22,
"acceptedAnswer": {
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"text": "Oui, la dystonie peut significativement affecter la qualité de vie en limitant les activités quotidiennes."
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"@type": "Question",
"name": "Y a-t-il des risques psychologiques associés à la dystonie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent éprouver de l'anxiété et de la dépression en raison de leur condition."
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"@type": "Question",
"name": "La dystonie peut-elle entraîner des blessures ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les mouvements involontaires peuvent causer des chutes et des blessures accidentelles."
}
},
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"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées ou améliorées avec un traitement approprié."
}
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{
"@type": "Question",
"name": "Quels sont les facteurs de risque de la dystonie ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des traumatismes crâniens et certaines maladies neurologiques."
}
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{
"@type": "Question",
"name": "L'âge influence-t-il le risque de dystonie ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la dystonie peut survenir à tout âge, mais certains types apparaissent plus souvent chez les jeunes adultes."
}
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{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque de dystonie ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent que les femmes peuvent être plus susceptibles de développer certains types de dystonie."
}
},
{
"@type": "Question",
"name": "Les maladies neurologiques augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des conditions comme la maladie de Parkinson peuvent augmenter le risque de dystonie."
}
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{
"@type": "Question",
"name": "Les médicaments peuvent-ils être un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments, comme les antipsychotiques, peuvent induire des symptômes de dystonie."
}
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Data used to train supervised machine learning models are commonly split into independent training, validation, and test sets. This paper illustrates that complex data leakage cases have occurred in t...
Machine learning (ML) has been extensively applied in brain imaging studies to aid the diagnosis of psychiatric disorders and the selection of potential biomarkers. Due to the high dimensionality of i...
Reproducibility is crucial for scientific progress, yet a clear research data analysis workflow is challenging to implement and maintain. As a result, a record of computational steps performed on the ...
The aim of this study was to assess the reproducibility and physiological determinants of mixed-meal tolerance tests (MMTTs) on glucose and insulin responses....
While inpatients on a weight-maintaining diet, 894 individuals (574 with normal and 267 with impaired glucose regulation and 53 with type 2 diabetes [T2D]) underwent 9-hour MMTTs (breakfast and lunch;...
In individuals without T2D, for breakfast-versus-lunch reproducibility of glucose, AUCs were moderate (intraclass correlation coefficients [ICCs]: 0.44-0.61), and iAUCs were poor (ICCs < 0.15). For re...
Reproducibility of glucose/insulin responses to MMTTs varied by subtraction of fasting values, glucose status, and time. Insulin secretion and action explained ~20% of MMTT responses. The substantial ...
We have developed a novel radiopaque tiltmeter (ROT) that can indicate patient tilt during a radiography examination and display it on X-ray images. This study evaluated the effect of variation of pat...
We evaluated the reproducibility of Fowler's position based on changes from the first day in the central venous catheter (CVC) tip position and the cardiothoracic ratio (CTR) with and without a digita...
With regard to reproducibility in Fowler's position, changes in the CVC tip position were 2.8 ± 3.9 mm and 10.7 ± 10.6 mm with and without the tiltmeter, respectively (p < 0.05) and the respective rat...
Our novel ROT had the potential to accurately indicate patient tilt during chest radiography, which could be helpful in terms of reproducibility and precise follow-up....
Use of the ROT for determination of patient tilt can improve reproducibility in Fowler's position, allowing more accurate serial X-ray imaging....
Studies have shown the incremental value of strain imaging in various cardiac diseases. However, reproducibility and generalizability has remained an issue of concern. To overcome this, simplified alg...
A total of 4 sites retrospectively identified 80 patients and 80 healthy controls who had undergone cardiac magnetic resonance imaging (CMR) at their respective centers using locally available scanner...
There was excellent agreement between sites in feature-tracking and rapid strain values (ICC ≥ 0.96). Bland-Altman plots showed no significant bias. Bi-atrial feature-tracking and rapid strains showed...
Simplified rapid left ventricular and bi-atrial strain parameters can be reliably applied in a real-world multicenter setting. Due to the results of the regression analysis, a minimum temporal resolut...
Similar immune responses in the nasal and bronchial mucosa implies that nasal allergen challenge (NAC) is a suitable early phase experimental model for drug development targeting allergic rhinitis (AR...
20 participants with mild atopic asthma and AR underwent three single blinded nasal challenges each separated by three weeks (NCT03431961). Cohort A (n = 10) underwent a control saline challenge, foll...
NAC significantly induced acute increases in nasosorption tryptase and TNSS and reduced PNIF, and induced late increases in nasosorption IL-13 with sustained reductions in PNIF. Reproducibility across...
NAC-induced biomarkers and symptoms are reproducible and responsive to INCS. NAC is suitable for assessing pharmacodynamic activity and proof of mechanism for drugs targeting allergic inflammation....
Large clinical trials often generate complex and large datasets which need to be presented frequently throughout the trial for interim analysis or to inform a data safety monitory board (DSMB). In add...
Ultrasound shear wave elastography (SWE) is a tool that can be utilized to assess biomechanical properties of tendons. Anisotropy, an ultrasound imaging artifact has been commonly cited as a potential...
After obtaining the Institutional Review Board approval and written informed consent, we prospectively measured the shear wave velocity (SWV) of patella tendons with and without tendinopathy in 25 vol...
Differences in SWV and anisotropy coefficient between normal tendons and tendons with tendinopathy were significant (p < 0.05). The intra- and inter-observer reproducibility in performing SWE were mod...
The results of this study suggest that SWE and anisotropy coefficient are feasible tools to differentiate patellar tendinopathy from normal patella tendons. The reproducibility of performing SWE of pa...