questionsmedicales.fr
Techniques d'investigation
Conservation biologique
Cryoconservation
Lyophilisation
Lyophilisation : Questions médicales fréquentes
Termes MeSH sélectionnés :
Angiotensin-Converting Enzyme 2
Diagnostic
2
Lyophilisation
Déshydratation
Analyse de la qualité
Contrôle de qualité
Symptômes
2
Produits alimentaires
Qualité des aliments
Prévention
2
Conservation
Stabilité des produits
Conditions de stockage
Humidité
Traitements
2
Réhydratation
Produits alimentaires
Conservation des aliments
Pharmaceutiques
Complications
2
Risque alimentaire
Dégradation
Produits périmés
Sécurité alimentaire
Facteurs de risque
2
Processus de lyophilisation
Température
Produits sensibles
Dégradation des aliments
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Lyophilisation : Questions médicales les plus fréquentes",
"headline": "Lyophilisation : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Lyophilisation : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-28",
"dateModified": "2025-04-22",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Lyophilisation"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Cryoconservation",
"url": "https://questionsmedicales.fr/mesh/D015925",
"about": {
"@type": "MedicalCondition",
"name": "Cryoconservation",
"code": {
"@type": "MedicalCode",
"code": "D015925",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "E05.760.156"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Congélation-dissolution",
"alternateName": "Freeze Substitution",
"url": "https://questionsmedicales.fr/mesh/D017110",
"about": {
"@type": "MedicalCondition",
"name": "Congélation-dissolution",
"code": {
"@type": "MedicalCode",
"code": "D017110",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "E05.760.156.260.270"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Lyophilisation",
"alternateName": "Freeze Drying",
"code": {
"@type": "MedicalCode",
"code": "D005612",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Davide Fissore",
"url": "https://questionsmedicales.fr/author/Davide%20Fissore",
"affiliation": {
"@type": "Organization",
"name": "Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. Electronic address: davide.fissore@polito.it."
}
},
{
"@type": "Person",
"name": "Nuria Martínez-Navarrete",
"url": "https://questionsmedicales.fr/author/Nuria%20Mart%C3%ADnez-Navarrete",
"affiliation": {
"@type": "Organization",
"name": "Food Technology Department, Food Investigation and Innovation Group, Universitat Politècnica de València, Valencia, Spain."
}
},
{
"@type": "Person",
"name": "Roberto Pisano",
"url": "https://questionsmedicales.fr/author/Roberto%20Pisano",
"affiliation": {
"@type": "Organization",
"name": "Department of Applied Science and Technology, Politecnico di Torino, 24 corso Duca degli Abruzzi, Torino 10129, Italy."
}
},
{
"@type": "Person",
"name": "Linlin Li",
"url": "https://questionsmedicales.fr/author/Linlin%20Li",
"affiliation": {
"@type": "Organization",
"name": "College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China."
}
},
{
"@type": "Person",
"name": "Weiwei Cao",
"url": "https://questionsmedicales.fr/author/Weiwei%20Cao",
"affiliation": {
"@type": "Organization",
"name": "College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Angiotensin-converting enzyme 2-at the heart of the COVID-19 pandemic.",
"datePublished": "2023-02-02",
"url": "https://questionsmedicales.fr/article/36787743",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.cell.2023.01.039"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effects of spike proteins on angiotensin converting enzyme 2 (ACE2).",
"datePublished": "2023-09-27",
"url": "https://questionsmedicales.fr/article/37769892",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.abb.2023.109769"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients.",
"datePublished": "2023-04-14",
"url": "https://questionsmedicales.fr/article/37060024",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s40360-023-00667-w"
}
},
{
"@type": "ScholarlyArticle",
"name": "Serum levels of angiotensin-converting enzyme 2 in children with Kawasaki disease.",
"datePublished": "2022-11-07",
"url": "https://questionsmedicales.fr/article/36344782",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s10238-022-00933-x"
}
},
{
"@type": "ScholarlyArticle",
"name": "Angiotensin-Converting Enzyme 2 (ACE2) Gene Polymorphism in Patients with Type 2 Diabetes (",
"datePublished": "2022-12-31",
"url": "https://questionsmedicales.fr/article/37274884",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.22092/ARI.2022.358736.2294"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Techniques d'investigation",
"item": "https://questionsmedicales.fr/mesh/D008919"
},
{
"@type": "ListItem",
"position": 3,
"name": "Conservation biologique",
"item": "https://questionsmedicales.fr/mesh/D011309"
},
{
"@type": "ListItem",
"position": 4,
"name": "Cryoconservation",
"item": "https://questionsmedicales.fr/mesh/D015925"
},
{
"@type": "ListItem",
"position": 5,
"name": "Lyophilisation",
"item": "https://questionsmedicales.fr/mesh/D005612"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Lyophilisation - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Lyophilisation",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-05",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Lyophilisation",
"description": "Comment savoir si un produit est lyophilisé ?\nQuels tests pour vérifier la qualité d'un produit lyophilisé ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Lyophilisation",
"description": "Quels sont les signes d'un produit mal lyophilisé ?\nY a-t-il des effets secondaires de la lyophilisation ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Lyophilisation",
"description": "Comment éviter la dégradation des produits lyophilisés ?\nQuelles conditions sont idéales pour stocker des produits lyophilisés ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Lyophilisation",
"description": "Comment réhydrater un produit lyophilisé ?\nQuels produits sont souvent lyophilisés ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Lyophilisation",
"description": "Quels risques si un produit lyophilisé est mal stocké ?\nPeut-on consommer un produit lyophilisé périmé ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Lyophilisation",
"description": "Quels facteurs influencent la qualité de la lyophilisation ?\nQuels produits sont plus sensibles à la lyophilisation ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Angiotensin-Converting+Enzyme+2#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment savoir si un produit est lyophilisé ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un produit lyophilisé est léger, friable et conserve sa forme d'origine après réhydratation."
}
},
{
"@type": "Question",
"name": "Quels tests pour vérifier la qualité d'un produit lyophilisé ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de solubilité, d'humidité résiduelle et d'analyse organoleptique sont effectués."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'un produit mal lyophilisé ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un produit mal lyophilisé peut présenter des grumeaux, une couleur anormale ou une odeur désagréable."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires de la lyophilisation ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "La lyophilisation n'a pas d'effets secondaires directs, mais peut altérer certains nutriments."
}
},
{
"@type": "Question",
"name": "Comment éviter la dégradation des produits lyophilisés ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Conservez-les dans un endroit frais, sec et à l'abri de la lumière pour préserver leur qualité."
}
},
{
"@type": "Question",
"name": "Quelles conditions sont idéales pour stocker des produits lyophilisés ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un environnement à faible humidité et température stable est idéal pour le stockage."
}
},
{
"@type": "Question",
"name": "Comment réhydrater un produit lyophilisé ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il suffit d'ajouter de l'eau à température ambiante ou chaude selon le produit."
}
},
{
"@type": "Question",
"name": "Quels produits sont souvent lyophilisés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les fruits, légumes, viandes et médicaments sont couramment lyophilisés pour la conservation."
}
},
{
"@type": "Question",
"name": "Quels risques si un produit lyophilisé est mal stocké ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mauvais stockage peut entraîner une perte de qualité, de goût et de valeur nutritionnelle."
}
},
{
"@type": "Question",
"name": "Peut-on consommer un produit lyophilisé périmé ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est déconseillé de consommer un produit périmé, même s'il semble intact."
}
},
{
"@type": "Question",
"name": "Quels facteurs influencent la qualité de la lyophilisation ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La température, la pression et la durée du processus de lyophilisation influencent la qualité."
}
},
{
"@type": "Question",
"name": "Quels produits sont plus sensibles à la lyophilisation ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les produits riches en graisses ou en sucres peuvent être plus sensibles à la dégradation."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 22/04/2025
Contenu vérifié selon les dernières recommandations médicales
6 publications dans cette catégorie
Affiliations :
Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. Electronic address: davide.fissore@polito.it.
3 publications dans cette catégorie
Affiliations :
Food Technology Department, Food Investigation and Innovation Group, Universitat Politècnica de València, Valencia, Spain.
Publications dans "Lyophilisation" :
3 publications dans cette catégorie
Affiliations :
Department of Applied Science and Technology, Politecnico di Torino, 24 corso Duca degli Abruzzi, Torino 10129, Italy.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Agricultural Product Drying Equipment Engineering Technology Research Center, Henan University of Science and Technology, Luoyang, China.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Agricultural Product Drying Equipment Engineering Technology Research Center, Henan University of Science and Technology, Luoyang, China.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Agricultural Product Drying Equipment Engineering Technology Research Center, Henan University of Science and Technology, Luoyang, China.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Agricultural Product Drying Equipment Engineering Technology Research Center, Henan University of Science and Technology, Luoyang, China.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
Agricultural Product Drying Equipment Engineering Technology Research Center, Henan University of Science and Technology, Luoyang, China.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
Laboratorio de Propiedades Físicas y Sensoriales y Ciencia del Consumidor, Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Valencia, Spain.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
Food Technology Department, Food Investigation and Innovation Group, Universitat Politècnica de València, Valencia, Spain.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Affiliations :
Millrock Technology, Inc., 39 Kieffer Ln, Kingston, NY, USA.
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
2 publications dans cette catégorie
Publications dans "Lyophilisation" :
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the COVID-19 pandemic, it has become one of the most therapeutically targeted human molecules in biomedicine. ACE2 serv...
The Coronavirus Disease 2019 (COVID-19) pandemic was caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which enters host cells through interactions of its spike protein to Angiot...
Renin-angiotensin-aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting enzyme 2 (ACE2) represents the main entrance of the virus, thus t...
A total of 40 healthy controls and 60 Egyptian patients suffering from chronic cardiovascular diseases were enrolled in this study. Patients were divided into 40 patients treated with ACEIs and 20 pat...
Assessment of serum ACE2 level in different groups showed a significant difference between ACEIs and healthy groups and ACEIs and ARBs group, while there was no difference between ARBs and healthy. Mu...
ACE2 levels varied between ACEIs and ARBs. It tends to be lower in ACEIs group and there is a strong positive association between ACE2 level and the female sex. This needs to be considered in Future s...
Retrospectively registered ClinicalTrials.gov ID: NCT05418361 (June 2022)....
Kawasaki disease (KD) has replaced rheumatic fever as the main cause of acquired heart disease in Japanese, American, and Chinese children. Polymorphisms in angiotensin-converting enzyme may be associ...
The increased levels of blood glucose associated with genetic and/or environmental risk factors have been known as Type 2 diabetes mellitus (T2D). T2D is categorized as a dangerous clinical syndrome f...
Rapid and cost-effective diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a critical and valuable weapon for the coronavirus disease 2019 (COVID-19) pandemic respo...
In order to prevent COVID-19 from progressing, angiotensin-converting enzyme 2 (ACE2) binds to SARS-CoV-2 and prevents the virus from entering target cells. Several studies have found a correlation be...
We conducted a systematic review using PubMed, Embase, Cochrane Library, Scopus, Science Direct and Web of Science databases. The odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. ...
It was concluded that the ACE2 G8790A polymorphism was not associated with COVID-19 based on the data collected. Moreover, subgroup analyses stratified based on race proved that the ACE2 G allele show...
The findings indicated that the G allele of ACE2 G8790A was related to an enhanced risk of COVID-19 severity in Asians. One possible reason is that ACE2 G allele was associated with a COVID-19 cytokin...
Systemic sclerosis (SSc) is a disease with cardiovascular impairment and polymorphisms of the gene coding of angiotensin-converting-enzyme 2 (ACE2) may account for its development. Three single nucleo...
Genomic DNA was isolated from whole blood. Restriction-fragment-length polymorphism was used for genotyping of rs1978124, while detection of rs879922 and rs2285666 was based on TaqMan SNP Genotyping A...
81 SSc patients (60 women, 21 men) were enrolled. Allele C of rs879922 polymorphism was associated with significantly greater risk for development of AH (OR=2.5, p=0.018), but less frequent joint invo...
Polymorphisms of ACE2 may account for the development of AH and CVS disorders in SSc patients. Strong tendencies to more frequent occurrence of disease specific characteristics distinct to macrovascul...
The quick and advancing prevalence of the new coronavirus SARS-CoV-2 produced a global crisis surge with a profound impact on human health and worldwide economic constancy. The virus is known as one s...
The Angiotensin-Converting Enzyme 2 (ACE2) is the main receptor of the SARS-CoV-2. There is contradictory evidence on how the exposure to nicotine may module the concentration of soluble ACE2 (sACE2)....
Pooled analysis performed with data retrieved from two studies (n = 634 and n = 302). Geometric mean (GM) concentrations of sACE2, both total and relative to the total amount of protein in the sample,...
We observed a significant increase of 0.108‰ and 0.087 ng/μl in the relative and absolute salivary sACE2 GM concentrations, respectively, between the lowest and highest nicotine levels. Similar result...
Salivary nicotine concentration seems to be limitedly associated with the concentration of sACE2....