Quels types de modifications subissent les protéines dans le Golgi ?
Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations.
GlycosylationPhosphorylationProtéines
#4
L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?
Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule.
Sécrétion cellulaireProtéinesAppareil de Golgi
#5
Quelles sont les structures associées à l'appareil de Golgi ?
Il est composé de citernes aplaties et de vésicules de transport.
VésiculesCisternesAppareil de Golgi
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Appareil de Golgi : Questions médicales les plus fréquentes",
"headline": "Appareil de Golgi : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Appareil de Golgi : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-29",
"dateModified": "2025-04-23",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Appareil de Golgi"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Organites",
"url": "https://questionsmedicales.fr/mesh/D015388",
"about": {
"@type": "MedicalCondition",
"name": "Organites",
"code": {
"@type": "MedicalCode",
"code": "D015388",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A11.284.430.214.190.875"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Réseau trans-golgien",
"alternateName": "trans-Golgi Network",
"url": "https://questionsmedicales.fr/mesh/D021601",
"about": {
"@type": "MedicalCondition",
"name": "Réseau trans-golgien",
"code": {
"@type": "MedicalCode",
"code": "D021601",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A11.284.430.214.190.875.336.850"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Appareil de Golgi",
"alternateName": "Golgi Apparatus",
"code": {
"@type": "MedicalCode",
"code": "D006056",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Akihiko Nakano",
"url": "https://questionsmedicales.fr/author/Akihiko%20Nakano",
"affiliation": {
"@type": "Organization",
"name": "RIKEN Center for Advanced Photonics, Wako, Japan."
}
},
{
"@type": "Person",
"name": "Christian Makhoul",
"url": "https://questionsmedicales.fr/author/Christian%20Makhoul",
"affiliation": {
"@type": "Organization",
"name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia."
}
},
{
"@type": "Person",
"name": "Paul A Gleeson",
"url": "https://questionsmedicales.fr/author/Paul%20A%20Gleeson",
"affiliation": {
"@type": "Organization",
"name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia."
}
},
{
"@type": "Person",
"name": "Doris Hellerschmied",
"url": "https://questionsmedicales.fr/author/Doris%20Hellerschmied",
"affiliation": {
"@type": "Organization",
"name": "Faculty of Biology, Center of Medical Biotechnology, University Duisburg-Essen, Essen, Germany. doris.hellerschmied@uni-due.de."
}
},
{
"@type": "Person",
"name": "Yanzhuang Wang",
"url": "https://questionsmedicales.fr/author/Yanzhuang%20Wang",
"affiliation": {
"@type": "Organization",
"name": "Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Identification and management of acute alcohol intoxication.",
"datePublished": "2022-08-16",
"url": "https://questionsmedicales.fr/article/35985955",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ejim.2022.08.013"
}
},
{
"@type": "ScholarlyArticle",
"name": "Acute Alcohol Intoxication in Pediatric Emergencies.",
"datePublished": "2022-07-24",
"url": "https://questionsmedicales.fr/article/35876736",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/PEC.0000000000002808"
}
},
{
"@type": "ScholarlyArticle",
"name": "Episodic foresight is impaired following acute alcohol intoxication.",
"datePublished": "2023-02-24",
"url": "https://questionsmedicales.fr/article/36825668",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1177/02698811231154851"
}
},
{
"@type": "ScholarlyArticle",
"name": "Role of Hemodialysis in Acute Severe Alcohol Intoxication: A Meta-Analysis.",
"datePublished": "2022-11-30",
"url": "https://questionsmedicales.fr/article/36450226",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1159/000527622"
}
},
{
"@type": "ScholarlyArticle",
"name": "Detection of Alcohol Intoxication Using Voice Features: A Controlled Laboratory Study.",
"datePublished": "2023-06-09",
"url": "https://questionsmedicales.fr/article/37306378",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.15288/jsad.22-00375"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Cellules",
"item": "https://questionsmedicales.fr/mesh/D002477"
},
{
"@type": "ListItem",
"position": 3,
"name": "Structures cellulaires",
"item": "https://questionsmedicales.fr/mesh/D022082"
},
{
"@type": "ListItem",
"position": 4,
"name": "Espace intracellulaire",
"item": "https://questionsmedicales.fr/mesh/D042541"
},
{
"@type": "ListItem",
"position": 5,
"name": "Cytoplasme",
"item": "https://questionsmedicales.fr/mesh/D003593"
},
{
"@type": "ListItem",
"position": 6,
"name": "Structures cytoplasmiques",
"item": "https://questionsmedicales.fr/mesh/D022083"
},
{
"@type": "ListItem",
"position": 7,
"name": "Organites",
"item": "https://questionsmedicales.fr/mesh/D015388"
},
{
"@type": "ListItem",
"position": 8,
"name": "Appareil de Golgi",
"item": "https://questionsmedicales.fr/mesh/D006056"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Appareil de Golgi - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Appareil de Golgi",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-19",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Recherche",
"headline": "Recherche sur Appareil de Golgi",
"description": "Quelles techniques sont utilisées pour étudier le Golgi ?\nQuels sont les modèles animaux pour étudier le Golgi ?\nComment les chercheurs étudient-ils les maladies du Golgi ?\nY a-t-il des traitements ciblant l'appareil de Golgi ?\nQuels sont les défis de la recherche sur le Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Alcoholic+Intoxication#section-recherche"
},
{
"@type": "MedicalWebPage",
"name": "Éducation",
"headline": "Éducation sur Appareil de Golgi",
"description": "Comment enseigner le rôle du Golgi en biologie ?\nQuels sont les concepts clés à enseigner sur le Golgi ?\nY a-t-il des ressources en ligne sur le Golgi ?\nComment les étudiants peuvent-ils visualiser le Golgi ?\nQuels sont les outils pédagogiques pour le Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Alcoholic+Intoxication#section-éducation"
},
{
"@type": "MedicalWebPage",
"name": "Pathologies",
"headline": "Pathologies sur Appareil de Golgi",
"description": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?\nComment les maladies du Golgi affectent-elles les cellules ?\nLes maladies génétiques peuvent-elles affecter l'appareil de Golgi ?\nQuels sont les symptômes d'une dysfonction de l'appareil de Golgi ?\nL'appareil de Golgi est-il impliqué dans le cancer ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Alcoholic+Intoxication#section-pathologies"
},
{
"@type": "MedicalWebPage",
"name": "Fonctionnalité",
"headline": "Fonctionnalité sur Appareil de Golgi",
"description": "Quel est le rôle principal de l'appareil de Golgi ?\nComment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?\nQuels types de modifications subissent les protéines dans le Golgi ?\nL'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?\nQuelles sont les structures associées à l'appareil de Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Alcoholic+Intoxication#section-fonctionnalité"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Quelles techniques sont utilisées pour étudier le Golgi ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la microscopie électronique et la biologie moléculaire sont utilisées."
}
},
{
"@type": "Question",
"name": "Quels sont les modèles animaux pour étudier le Golgi ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les souris et les drosophiles sont souvent utilisés pour étudier les fonctions du Golgi."
}
},
{
"@type": "Question",
"name": "Comment les chercheurs étudient-ils les maladies du Golgi ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils utilisent des modèles cellulaires et des études génétiques pour comprendre les mécanismes."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements ciblant l'appareil de Golgi ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours pour développer des thérapies ciblant les dysfonctionnements du Golgi."
}
},
{
"@type": "Question",
"name": "Quels sont les défis de la recherche sur le Golgi ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les défis incluent la complexité de ses fonctions et la diversité des maladies associées."
}
},
{
"@type": "Question",
"name": "Comment enseigner le rôle du Golgi en biologie ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser des modèles 3D et des animations pour illustrer ses fonctions et interactions."
}
},
{
"@type": "Question",
"name": "Quels sont les concepts clés à enseigner sur le Golgi ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les concepts de modification des protéines, de transport et de pathologies associées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des ressources en ligne sur le Golgi ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des sites éducatifs et des vidéos explicatives sont disponibles en ligne."
}
},
{
"@type": "Question",
"name": "Comment les étudiants peuvent-ils visualiser le Golgi ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent utiliser des logiciels de modélisation et des images de microscopie."
}
},
{
"@type": "Question",
"name": "Quels sont les outils pédagogiques pour le Golgi ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des manuels, des vidéos et des simulations interactives sont des outils efficaces."
}
},
{
"@type": "Question",
"name": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies comme le syndrome de Golgi et certaines maladies neurodégénératives."
}
},
{
"@type": "Question",
"name": "Comment les maladies du Golgi affectent-elles les cellules ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des défauts de sécrétion et des accumulations de protéines."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques peuvent-elles affecter l'appareil de Golgi ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines mutations génétiques peuvent perturber sa fonction."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une dysfonction de l'appareil de Golgi ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des troubles métaboliques et des anomalies cellulaires."
}
},
{
"@type": "Question",
"name": "L'appareil de Golgi est-il impliqué dans le cancer ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des altérations de son fonctionnement peuvent contribuer à la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quel est le rôle principal de l'appareil de Golgi ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il modifie, trie et emballe les protéines et lipides pour leur transport."
}
},
{
"@type": "Question",
"name": "Comment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il reçoit des protéines du réticulum endoplasmique pour les modifier et les expédier."
}
},
{
"@type": "Question",
"name": "Quels types de modifications subissent les protéines dans le Golgi ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations."
}
},
{
"@type": "Question",
"name": "L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule."
}
},
{
"@type": "Question",
"name": "Quelles sont les structures associées à l'appareil de Golgi ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est composé de citernes aplaties et de vésicules de transport."
}
}
]
}
]
}
The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France; Sorbonne Université, UPMC University Paris 06, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France.
Acute alcohol intoxication (AAI) is a harmful clinical condition, potentially life-threatening, secondary to the intake of large amounts of alcohol. Clinical manifestations of AAI are characterized by...
Alcohol intoxication in pediatrics is a growing problem in our environment. The objectives of this study are to define the prevalence of acute alcohol intoxication in the pediatric emergency departmen...
This cross-sectional study includes patients younger than 16 years with a diagnosis of acute alcohol intoxication between March 2010 and October 2018 in the PED of a tertiary hospital. Patients with c...
There were 136 episodes of alcohol intoxication, which represents a prevalence of 24.1/100,000 emergencies. After excluding 10 patients because of positive screening for other drugs, 126 patients with...
Alcohol intoxication is a rare consultation reason in the PED. They usually present with mild and self-limited symptoms, being the decrease in the level of consciousness and hypokalemia the most frequ...
Alcohol intoxication disrupts many aspects of cognition, including the generation of phenomenological characteristics of future events (a component of episodic foresight), and the execution of directe...
This study was designed to provide the first test of how alcohol intoxication influences the functional application of episodic foresight. The secondary aim was to establish the degree to which any ob...
Healthy adult social drinkers randomly received either a moderate dose of 0.6 g/kg alcohol (...
Relative to the placebo condition, episodic foresight was impaired by acute alcohol consumption, with this impairment related to poorer retrospective memory, but not executive control. The negative ef...
Even a moderate level of intoxication impairs the ability to use episodic foresight in a functionally adaptive way. These findings have implications for understanding many of the maladaptive behaviour...
Hemodialysis therapy has been used in the treatment of acute alcohol intoxication for many years, especially acute severe alcohol intoxication....
This study aimed to evaluate whether the combination of conventional treatment and naloxone with hemodialysis has advantages over conventional treatment and naloxone alone in patients with acute sever...
After searching 12 databases and 2 clinical trial centers. According to the established inclusion and exclusion criteria, the qualified literatures were screened. The outcome indicators were length of...
This meta-analysis included 13 studies, including 932 subjects. In the treatment of acute severe alcohol intoxication, the use of hemodialysis on the basis of conventional treatment and naloxone could...
It can be concluded that compared with the use of conventional treatment and naloxone alone, the use of hemodialysis on the basis of conventional treatment and naloxone for acute severe alcohol intoxi...
Devices such as mobile phones and smart speakers could be useful to remotely identify voice alterations associated with alcohol intoxication that could be used to deliver just-in-time interventions, b...
A total of 18 participants (72% male, ages 21-62 years) read a randomly assigned tongue twister before drinking and each hour for up to 7 hours after drinking a weight-based dose of alcohol. Vocal seg...
Alcohol intoxication was predicted with an accuracy of 98% (95% CI [97.1, 98.6]); mean sensitivity = .98; specificity = .97; positive predictive value = .97; and negative predictive value = .98....
In this small, controlled laboratory study, voice spectrographic signatures collected from brief recorded English segments were useful in identifying alcohol intoxication. Larger studies using varied ...
This study aims to explore the prevalence of creatinine kinase elevation amongst a sample of Dutch adolescents admitted for acute alcohol intoxication. The data on all admitted adolescents < 18 years ...
Drug and alcohol intoxication is common among injured patients altering trauma presentation and characteristics. However, uncertainty exists regarding the effect of intoxication on injury severity, as...
All major trauma patients captured in our centre's Trauma Registry between July 2010 and June 2020 were included. Demographic, injury characteristic, outcome and substance-use data were collected. Dif...
Among 9700 patients, 9% were drug-intoxicated prior to injury, while 9.4% were alcohol-intoxicated. Drug use almost tripled between 2010 (4.8%) and 2020 (13.3%), while alcohol intoxication fell, from ...
Within this contemporary Australian population, we demonstrate escalating rates of drug intoxication and declining rates of alcohol intoxication prior to trauma. Intoxication was associated with more ...
The toxic properties of ethanol are inextricably linked to oxidative stress. Despite many reports on the effects of alcohol dependence on blood redox homeostasis, there are no data on the oxidative st...
Alcohol is one of the most commonly used substances and frequently abused, yet little is known about the neural underpinnings driving variability in inhibitory control performance after ingesting alco...
When evaluating an emergency department (ED) patient who presents with suicidal ideation, it is a common practice to wait until the patient's ethanol level is known or calculated to be less than 80 mg...
We conducted a retrospective review of patients evaluated in a Midwestern ED for the calendar year 2017. Cases were selected if they had a psychiatric social work consult and a blood alcohol level dra...
Among patients presenting with suicidal ideation and a concurrent BAL ≥80 mg/dl, 69% no longer reported suicidal ideation when their BAL was <80 mg/dl, compared to 38% for patients without a positive ...
Our data show that patients presenting to the ED with complaints related to suicidal behavior who have a BAL ≥80 mg/dl are more likely to no longer endorse having suicidal ideation once their BAL is <...