Quels types de modifications subissent les protéines dans le Golgi ?
Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations.
GlycosylationPhosphorylationProtéines
#4
L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?
Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule.
Sécrétion cellulaireProtéinesAppareil de Golgi
#5
Quelles sont les structures associées à l'appareil de Golgi ?
Il est composé de citernes aplaties et de vésicules de transport.
VésiculesCisternesAppareil de Golgi
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The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France; Sorbonne Université, UPMC University Paris 06, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France.
Chronic Obstructive Pulmonary Disease (COPD) is a disease that is spreading worldwide and is responsible for a huge number of deaths annually. It is characterized by progressive and often irreversible...
Background and Objectives: Muscle blood flow is impeded during resistance exercise contractions, but immediately increases during recovery. The purpose of this study was to determine the impact of bri...
Patients with chronic obstructive pulmonary disease (COPD) have difficulties inhaling as the diaphragm becomes flattened and weakened due to lung hyperinflation. This weakened respiratory function is ...
This study aimed to evaluate the difference in the SCM thickening fraction (SCM TF) of each respiratory phase (end-expiration, resting inspiration, and end-inspiration), as measured using ultrasonogra...
Patients with COPD (n = 44) and age-matched controls (n = 20) underwent US for determination of the SCM TF. Ventilation parameters, including the peak oxygen uptake (peak VO2) and the change in the in...
The SCM was significantly thinner in patients with COPD than in controls at end-expiration. The increase in the SCM TF from end-expiration to end-inspiration in patients with COPD did not differ signi...
The SCM may be thinner in patients with COPD than in controls. The SCM TF may also be associated with exercise tolerance....
What is the central question of this study? Does prescribing exercise intensity using physiological thresholds create a more homogeneous exercise stimulus than using traditional intensity anchors? Wha...
The objective of this study was to determine whether the variability in exercise tolerance and physiological responses is lower when exercise is prescribed relative to physiological thresholds (THR) c...
Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This...
Twenty-three patients with MS (13 women) and 20 age-matched and sex-matched healthy controls (13 women) performed a cardiopulmonary exercise test. Muscle fibre type composition, size, succinate dehydr...
Patients with MS had lower maximal oxygen uptake compared with healthy controls (V̇O...
Skeletal muscle oxidative phenotype (mitochondrial complex I and II content, SDH activity) is lower in patients with MS, contributing to reduced exercise tolerance. However, skeletal muscle mitochondr...
Following ST-segment elevation myocardial infarction (STEMI), patients with cardiac dysfunction have limitations in performing physical activity. Right ventricular (RV) function is a determinant in im...
To evaluate the association of RV function with exercise tolerance after a CR program in patients with STEMI....
Retrospective cohort study in patients with STEMI from January to December 2019. They underwent an echocardiographic assessment of RV function before a 16-session CR program. A cardiopulmonary exercis...
A total of 109 patients were included. Of all, 3.7% had global RV dysfunction, 10.1% had radial RV dysfunction, and 11% had longitudinal RV dysfunction. An association between radial or longitudinal R...
RV dysfunction is associated with a lower capacity to exercise; CR programs can be extended or modified in these patients....
The Buffalo Concussion Treadmill Test (BCTT) is a standard assessment of exercise tolerance utilized for exercise prescription following concussion and to inform decisions regarding return to play. On...
Prospective cohort study, pretest/posttest....
A total of 30 participants included 13 women (43.3%), age 23.4 (1.93) years, height 173.56 (10) cm, weight 77.35 (16.3) kg, and 11 (36.7%) with history of concussion. All participants completed a neur...
BCTT: Average percentage of heart rate maximum (%HRmax) = 93.97% (4.8%); average maximum rating of perceived exertion = 18.6 (1.5). Time-based performance in single-task and dual-task conditions signi...
Healthy participants demonstrated improvements across multiple domains of neurocognitive performance following the exercise tolerance testing on the BCTT. Understanding normal responses in neurocognit...
Critical torque (CT) and work done above it ( W ') are key predictors of exercise performance associated with neuromuscular fatigue. The aim of the present study was to understand the role of the meta...
Twelve subjects performed four knee extension time trials (6, 8, 10, and 12 min) using eccentric, isometric, or concentric contractions (3-s on/2-s off at 90°·s -1 or 30°·s -1 ) to modulate the metabo...
Compared with isometric exercise, total impulse (+36% ± 21%; P < 0.001), CT (+27% ± 30%; P < 0.001), and W ' (+67% ± 99%; P < 0.001) were increased during eccentric exercise, whereas total impulse (-2...
The contraction mode influenced both CT and W ', and consequently exercise tolerance, indicating that the metabolic cost of contraction played a key role....
In patients with chronic obstructive pulmonary disease (COPD), the clinical use of the minute ventilation-carbon dioxide production ([Formula: see text]...
We hypothesized that the [Formula: see text]...
Compared with the GOLD I-II group (n = 51), peak [Formula: see text]...
The OUES may be less useful in advanced COPD with exertional hypoxemia. The [Formula: see text]...
COVID-19 is not only a short-term infection, as patients (pts) recovering from SARS-CoV-2 infection complain of persisting symptoms, which may lead to chronic fatigue syndrome. There is currently no e...
The study population was composed of 50 pts who had recovered from symptomatic COVID-19. The selected pts were randomized into two groups: Gr 1 (NO-1-MNA)-without supplementation; Gr 2 (1-MNA) with 1-...
A significant improvement in the mean distance covered in the 6MWT was noted at follow-up in Gr 1-MNA, compared with Gr NO-1-MNA. We also noted that in Gr 1-MNA, the 6MWT distance was significantly hi...
1-MNA supplementation significantly improved physical performance in a 6-min walk test and reduced the percentage of patients with severe fatigue after COVID-19. The comprehensive action of 1-MNA, inc...