Titre : Appareil de Golgi

Appareil de Golgi : Questions médicales fréquentes

Termes MeSH sélectionnés :

Logistic Models
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Appareil de Golgi : Questions médicales les plus fréquentes", "headline": "Appareil de Golgi : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Appareil de Golgi : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-01-29", "dateModified": "2025-04-23", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Appareil de Golgi" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Organites", "url": "https://questionsmedicales.fr/mesh/D015388", "about": { "@type": "MedicalCondition", "name": "Organites", "code": { "@type": "MedicalCode", "code": "D015388", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "A11.284.430.214.190.875" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Réseau trans-golgien", "alternateName": "trans-Golgi Network", "url": "https://questionsmedicales.fr/mesh/D021601", "about": { "@type": "MedicalCondition", "name": "Réseau trans-golgien", "code": { "@type": "MedicalCode", "code": "D021601", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "A11.284.430.214.190.875.336.850" } } } ], "about": { "@type": "MedicalCondition", "name": "Appareil de Golgi", "alternateName": "Golgi Apparatus", "code": { "@type": "MedicalCode", "code": "D006056", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Akihiko Nakano", "url": "https://questionsmedicales.fr/author/Akihiko%20Nakano", "affiliation": { "@type": "Organization", "name": "RIKEN Center for Advanced Photonics, Wako, Japan." } }, { "@type": "Person", "name": "Christian Makhoul", "url": "https://questionsmedicales.fr/author/Christian%20Makhoul", "affiliation": { "@type": "Organization", "name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia." } }, { "@type": "Person", "name": "Paul A Gleeson", "url": "https://questionsmedicales.fr/author/Paul%20A%20Gleeson", "affiliation": { "@type": "Organization", "name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia." } }, { "@type": "Person", "name": "Doris Hellerschmied", "url": "https://questionsmedicales.fr/author/Doris%20Hellerschmied", "affiliation": { "@type": "Organization", "name": "Faculty of Biology, Center of Medical Biotechnology, University Duisburg-Essen, Essen, Germany. doris.hellerschmied@uni-due.de." } }, { "@type": "Person", "name": "Yanzhuang Wang", "url": "https://questionsmedicales.fr/author/Yanzhuang%20Wang", "affiliation": { "@type": "Organization", "name": "Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Design and Implementation of Smart Community Big Data Dynamic Analysis Model Based on Logistic Regression Model.", "datePublished": "2022-06-22", "url": "https://questionsmedicales.fr/article/35785068", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1155/2022/4038084" } }, { "@type": "ScholarlyArticle", "name": "Prediction of protein aggregation propensity employing SqFt-based logistic regression model.", "datePublished": "2023-07-27", "url": "https://questionsmedicales.fr/article/37516225", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.ijbiomac.2023.126036" } }, { "@type": "ScholarlyArticle", "name": "Multiple logistic regression model to predict bile leak associated with subtotal cholecystectomy.", "datePublished": "2023-04-04", "url": "https://questionsmedicales.fr/article/37016083", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s00464-023-10049-2" } }, { "@type": "ScholarlyArticle", "name": "A noble extended stochastic logistic model for cell proliferation with density-dependent parameters.", "datePublished": "2022-05-30", "url": "https://questionsmedicales.fr/article/35637247", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1038/s41598-022-12719-y" } }, { "@type": "ScholarlyArticle", "name": "Combining proteomic markers to construct a logistic regression model for polycystic ovary syndrome.", "datePublished": "2023-10-03", "url": "https://questionsmedicales.fr/article/37854181", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3389/fendo.2023.1227252" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Cellules", "item": "https://questionsmedicales.fr/mesh/D002477" }, { "@type": "ListItem", "position": 3, "name": "Structures cellulaires", "item": "https://questionsmedicales.fr/mesh/D022082" }, { "@type": "ListItem", "position": 4, "name": "Espace intracellulaire", "item": "https://questionsmedicales.fr/mesh/D042541" }, { "@type": "ListItem", "position": 5, "name": "Cytoplasme", "item": "https://questionsmedicales.fr/mesh/D003593" }, { "@type": "ListItem", "position": 6, "name": "Structures cytoplasmiques", "item": "https://questionsmedicales.fr/mesh/D022083" }, { "@type": "ListItem", "position": 7, "name": "Organites", "item": "https://questionsmedicales.fr/mesh/D015388" }, { "@type": "ListItem", "position": 8, "name": "Appareil de Golgi", "item": "https://questionsmedicales.fr/mesh/D006056" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Appareil de Golgi - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Appareil de Golgi", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-18", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Recherche", "headline": "Recherche sur Appareil de Golgi", "description": "Quelles techniques sont utilisées pour étudier le Golgi ?\nQuels sont les modèles animaux pour étudier le Golgi ?\nComment les chercheurs étudient-ils les maladies du Golgi ?\nY a-t-il des traitements ciblant l'appareil de Golgi ?\nQuels sont les défis de la recherche sur le Golgi ?", "url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Logistic+Models&page=2#section-recherche" }, { "@type": "MedicalWebPage", "name": "Éducation", "headline": "Éducation sur Appareil de Golgi", "description": "Comment enseigner le rôle du Golgi en biologie ?\nQuels sont les concepts clés à enseigner sur le Golgi ?\nY a-t-il des ressources en ligne sur le Golgi ?\nComment les étudiants peuvent-ils visualiser le Golgi ?\nQuels sont les outils pédagogiques pour le Golgi ?", "url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Logistic+Models&page=2#section-éducation" }, { "@type": "MedicalWebPage", "name": "Pathologies", "headline": "Pathologies sur Appareil de Golgi", "description": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?\nComment les maladies du Golgi affectent-elles les cellules ?\nLes maladies génétiques peuvent-elles affecter l'appareil de Golgi ?\nQuels sont les symptômes d'une dysfonction de l'appareil de Golgi ?\nL'appareil de Golgi est-il impliqué dans le cancer ?", "url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Logistic+Models&page=2#section-pathologies" }, { "@type": "MedicalWebPage", "name": "Fonctionnalité", "headline": "Fonctionnalité sur Appareil de Golgi", "description": "Quel est le rôle principal de l'appareil de Golgi ?\nComment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?\nQuels types de modifications subissent les protéines dans le Golgi ?\nL'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?\nQuelles sont les structures associées à l'appareil de Golgi ?", "url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Logistic+Models&page=2#section-fonctionnalité" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Quelles techniques sont utilisées pour étudier le Golgi ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques comme la microscopie électronique et la biologie moléculaire sont utilisées." } }, { "@type": "Question", "name": "Quels sont les modèles animaux pour étudier le Golgi ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les souris et les drosophiles sont souvent utilisés pour étudier les fonctions du Golgi." } }, { "@type": "Question", "name": "Comment les chercheurs étudient-ils les maladies du Golgi ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Ils utilisent des modèles cellulaires et des études génétiques pour comprendre les mécanismes." } }, { "@type": "Question", "name": "Y a-t-il des traitements ciblant l'appareil de Golgi ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches sont en cours pour développer des thérapies ciblant les dysfonctionnements du Golgi." } }, { "@type": "Question", "name": "Quels sont les défis de la recherche sur le Golgi ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les défis incluent la complexité de ses fonctions et la diversité des maladies associées." } }, { "@type": "Question", "name": "Comment enseigner le rôle du Golgi en biologie ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Utiliser des modèles 3D et des animations pour illustrer ses fonctions et interactions." } }, { "@type": "Question", "name": "Quels sont les concepts clés à enseigner sur le Golgi ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les concepts de modification des protéines, de transport et de pathologies associées." } }, { "@type": "Question", "name": "Y a-t-il des ressources en ligne sur le Golgi ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des sites éducatifs et des vidéos explicatives sont disponibles en ligne." } }, { "@type": "Question", "name": "Comment les étudiants peuvent-ils visualiser le Golgi ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent utiliser des logiciels de modélisation et des images de microscopie." } }, { "@type": "Question", "name": "Quels sont les outils pédagogiques pour le Golgi ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des manuels, des vidéos et des simulations interactives sont des outils efficaces." } }, { "@type": "Question", "name": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Des maladies comme le syndrome de Golgi et certaines maladies neurodégénératives." } }, { "@type": "Question", "name": "Comment les maladies du Golgi affectent-elles les cellules ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent entraîner des défauts de sécrétion et des accumulations de protéines." } }, { "@type": "Question", "name": "Les maladies génétiques peuvent-elles affecter l'appareil de Golgi ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines mutations génétiques peuvent perturber sa fonction." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une dysfonction de l'appareil de Golgi ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent inclure des troubles métaboliques et des anomalies cellulaires." } }, { "@type": "Question", "name": "L'appareil de Golgi est-il impliqué dans le cancer ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des altérations de son fonctionnement peuvent contribuer à la progression tumorale." } }, { "@type": "Question", "name": "Quel est le rôle principal de l'appareil de Golgi ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Il modifie, trie et emballe les protéines et lipides pour leur transport." } }, { "@type": "Question", "name": "Comment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Il reçoit des protéines du réticulum endoplasmique pour les modifier et les expédier." } }, { "@type": "Question", "name": "Quels types de modifications subissent les protéines dans le Golgi ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations." } }, { "@type": "Question", "name": "L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule." } }, { "@type": "Question", "name": "Quelles sont les structures associées à l'appareil de Golgi ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Il est composé de citernes aplaties et de vésicules de transport." } } ] } ] }

Sources (10000 au total)

Multiple logistic regression model to predict bile leak associated with subtotal cholecystectomy.

There are no prediction models for bile leakage associated with subtotal cholecystectomy (STC). Therefore, this study aimed to generate a multivariable prediction model for post-STC bile leakage and e... We analysed prospectively managed data of patients who underwent STC by a single consultant surgeon between 14 May 2013 and 21 December 2021. STC was schematised into four variants with five subvarian... A total of 81 patients underwent the STC procedure. Twenty-eight patients (35%) developed bile leakage. Of these, 18 patients (64%) required secondary surgical intervention. Multivariable logistic reg... Open-tract STC and acute cholecystitis are the most reliable predictors of bile leakage associated with STC. Future prospective, multicentre studies with higher statistical power are needed to generat...

Combining proteomic markers to construct a logistic regression model for polycystic ovary syndrome.

Proteomics technology has been used in various fields in recent years for the Q6 exploration of novel markers and the study of disease pathogenesis, and has become one of the most important tools for ... In our previous study we used DIA proteomics to screen for proteins that were significant in 31 PCOS patients compared to women of normal reproductive age. In this study, we used logistic regression a... We constructed a logistic model using these protein markers, where HIST1H4A (OR=1.037) was an independent risk factor for polycystic ovary syndrome and TREML1 (OR=0.976) were protective factors for th... Our study is the first to use proteomic results with clinical biochemical data to construct a logistic regression model, and the model is consistent. However, our study still needs a more complete sam...

Establishment of HIV-negative neurosyphilis risk score model based on logistic regression.

To establish the risk scoring model for HIV-negative neurosyphilis (NS) patients and to optimize the lumbar puncture strategy.... From 2016 to 2021, clinical information on 319 syphilis patients was gathered. Multivariate logistic regression was used to examine the independent risk factors in NS patients who tested negative for ... There were statistically significant differences between HIV-negative NS and non-neurosyphilis (NNS) patients in the following factors. These included age, gender, neuropsychiatric symptoms (including... The risk scoring model in this study can classify the risk of neurosyphilis in syphilis patients, optimize the lumbar puncture strategy to a certain extent, and provide ideas for the clinical diagnosi...

Adjustment for baseline characteristics in randomized trials using logistic regression: sample-based model versus true model.

Adjustment for baseline prognostic factors in randomized clinical trials is usually performed by means of sample-based regression models. Sample-based models may be incorrect due to overfitting. To as... We conducted a simulation study using samples drawn from a "population" in which both the treatment effect and the effect of the potential confounder were specified. The outcome variable was binary. U... Sample-based adjustment models yielded more biased estimates of the treatment effect than adjustment models that used the true confounder effect but had similar variance, accuracy, power, and type 1 e... Sample-based adjustment yields similar results to exact adjustment in estimating the treatment effect. Sample-based adjustment is preferable to no adjustment....

A calibration and uncertainty quantification analysis of classical, fractional and multiscale logistic models of tumour growth.

The validation of mathematical models of tumour growth is frequently hampered by the lack of sufficient experimental data, resulting in qualitative rather than quantitative studies. Recent approaches ... The multiscale expansion of logistic growth models was performed by coupling gene expression profiles to the cell death rates. State-of-the-art Bayesian inference, likelihood maximisation and uncertai... The results suggest that the classical single-cell population model (SCPM) was the best fit for the untreated and low-dose treatment conditions, while the multiscale model with a cell death rate symme... Overall, the present study demonstrates that model performance can be improved by incorporating multiscale measurements of tumour growth when high-dose treatment is involved....

Minimum sample size for developing a multivariable prediction model using multinomial logistic regression.

Multinomial logistic regression models allow one to predict the risk of a categorical outcome with > 2 categories. When developing such a model, researchers should ensure the number of participants (... The first criterion aims to minimise the model overfitting. The second aims to minimise the difference between the observed and adjusted... We tested the performance of the proposed criteria (i) through a simulation study and found that it resulted in the desired level of overfitting. Criterion (ii) and (iii) were natural extensions from ... We illustrated how to implement the sample size criteria through a worked example considering the development of a multinomial risk prediction model for tumour type when presented with an ovarian mass...

A novel multivariate logistic model for predicting risk factors of failed treatment with carbapenem-resistant

This study aimed to explore the risk factors for failed treatment of carbapenem-resistant... A total of 189 CRAB-VAP patients were included in the safety analysis set from two Grade 3 A national-level hospitals between 1 January 2022 and 31 December 2022. The risk factors for failed treatment... Of the 189 patients, 106 (56.1%) patients were in the successful treatment group, and 83 (43.9%) patients were in the failed treatment group. The multivariate logistic model analysis showed that age (... Age, hypoproteinemia, daily dose, medication within 14 days prior to surgical intervention, and microbial clearance are all significant risk factors for failed treatment with CRAB-VAP, with the nomogr...