questionsmedicales.fr
Systèmes sanguin et immunitaire
Système immunitaire
Leucocytes
Granulocytes
Granulocytes : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Granulocytes
Granulocytopénie
Numération formule sanguine
Granulocytes
Symptômes
5
Granulocytopénie
Infection
Réaction allergique
Granulocytes
Inflammation
Granulocytes
Infection bactérienne
Granulocytes
Prévention
5
Prévention des infections
Granulocytes
Complications
Granulocytes
Traitements
5
Granulocytopénie
Transfusion
Corticostéroïdes
Inflammation
Greffe de moelle osseuse
Granulocytes
Complications
5
Granulocytopénie
Infection
Leucémie myéloïde
Granulocytes
Cicatrisation
Granulocytes
Immunosuppresseurs
Granulocytes
Effets secondaires
Granulocytes
Facteurs de risque
5
Immunodépression
Infection
Maladies auto-immunes
Granulocytes
Produits chimiques
Granulocytes
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Granulocytes : Questions médicales les plus fréquentes",
"headline": "Granulocytes : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Granulocytes : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-04-22",
"dateModified": "2025-04-17",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Granulocytes"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Leucocytes",
"url": "https://questionsmedicales.fr/mesh/D007962",
"about": {
"@type": "MedicalCondition",
"name": "Leucocytes",
"code": {
"@type": "MedicalCode",
"code": "D007962",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A15.382.490"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Granulocytes basophiles",
"alternateName": "Basophils",
"url": "https://questionsmedicales.fr/mesh/D001491",
"about": {
"@type": "MedicalCondition",
"name": "Granulocytes basophiles",
"code": {
"@type": "MedicalCode",
"code": "D001491",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A15.382.490.315.120"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Granulocytes éosinophiles",
"alternateName": "Eosinophils",
"url": "https://questionsmedicales.fr/mesh/D004804",
"about": {
"@type": "MedicalCondition",
"name": "Granulocytes éosinophiles",
"code": {
"@type": "MedicalCode",
"code": "D004804",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A15.382.490.315.251"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Granulocytes",
"alternateName": "Granulocytes",
"code": {
"@type": "MedicalCode",
"code": "D006098",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Cathy Conry-Cantilena",
"url": "https://questionsmedicales.fr/author/Cathy%20Conry-Cantilena",
"affiliation": {
"@type": "Organization",
"name": "Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD."
}
},
{
"@type": "Person",
"name": "Michael Gruber",
"url": "https://questionsmedicales.fr/author/Michael%20Gruber",
"affiliation": {
"@type": "Organization",
"name": "Department of Anesthesiology, University Hospital Regensburg, Raubling, Germany."
}
},
{
"@type": "Person",
"name": "Hans-Uwe Simon",
"url": "https://questionsmedicales.fr/author/Hans-Uwe%20Simon",
"affiliation": {
"@type": "Organization",
"name": "Institute of Pharmacology, University of Bern, Bern, Switzerland; email: thomas.kaufmann@pki.unibe.ch, hans-uwe.simon@pki.unibe.ch."
}
},
{
"@type": "Person",
"name": "Yu Hao",
"url": "https://questionsmedicales.fr/author/Yu%20Hao",
"affiliation": {
"@type": "Organization",
"name": "Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China."
}
},
{
"@type": "Person",
"name": "Can Zhang",
"url": "https://questionsmedicales.fr/author/Can%20Zhang",
"affiliation": {
"@type": "Organization",
"name": "Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "LC-MS/MS method for proline-glycine-proline and acetylated proline-glycine-proline in human plasma.",
"datePublished": "2023-07-05",
"url": "https://questionsmedicales.fr/article/37453387",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jchromb.2023.123815"
}
},
{
"@type": "ScholarlyArticle",
"name": "Microbial Proline Racemase-Proline Dehydrogenase Cascade for Efficient Production of D-proline and N-boc-5-hydroxy-L-proline from L-proline.",
"datePublished": "2022-05-30",
"url": "https://questionsmedicales.fr/article/35635604",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s12010-022-03980-y"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cu(Proline)",
"datePublished": "2022-09-09",
"url": "https://questionsmedicales.fr/article/36144582",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/molecules27185846"
}
},
{
"@type": "ScholarlyArticle",
"name": "d-Proline Reductase Underlies Proline-Dependent Growth of Clostridioides difficile.",
"datePublished": "2022-07-13",
"url": "https://questionsmedicales.fr/article/35862761",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1128/jb.00229-22"
}
},
{
"@type": "ScholarlyArticle",
"name": "Proline interacts with Ca",
"datePublished": "2023-09-01",
"url": "https://questionsmedicales.fr/article/37660866",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ijbiomac.2023.126655"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Systèmes sanguin et immunitaire",
"item": "https://questionsmedicales.fr/mesh/D006424"
},
{
"@type": "ListItem",
"position": 3,
"name": "Système immunitaire",
"item": "https://questionsmedicales.fr/mesh/D007107"
},
{
"@type": "ListItem",
"position": 4,
"name": "Leucocytes",
"item": "https://questionsmedicales.fr/mesh/D007962"
},
{
"@type": "ListItem",
"position": 5,
"name": "Granulocytes",
"item": "https://questionsmedicales.fr/mesh/D006098"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Granulocytes - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Granulocytes",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-16",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Granulocytes",
"description": "Comment diagnostiquer une granulocytopénie ?\nQuels tests pour évaluer les granulocytes ?\nQuels signes indiquent une infection liée aux granulocytes ?\nComment évaluer la fonction des granulocytes ?\nQuel rôle joue la biopsie dans le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Granulocytes",
"description": "Quels symptômes d'une carence en granulocytes ?\nComment se manifeste une réaction allergique ?\nQuels symptômes d'une inflammation ?\nQuels signes d'une infection bactérienne ?\nQuels symptômes d'une leucémie ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Granulocytes",
"description": "Comment prévenir les infections chez les patients à faible granulocytes ?\nQuels vaccins sont recommandés ?\nComment éviter les complications liées aux granulocytes ?\nQuel rôle de l'alimentation dans la prévention ?\nComment gérer le stress pour la santé des granulocytes ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Granulocytes",
"description": "Comment traiter une granulocytopénie ?\nQuels médicaments stimulent les granulocytes ?\nComment traiter une infection liée aux granulocytes ?\nQuel rôle des corticostéroïdes dans le traitement ?\nQuand envisager une greffe de moelle osseuse ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Granulocytes",
"description": "Quelles complications d'une granulocytopénie sévère ?\nQuels risques d'une leucémie myéloïde ?\nComment les granulocytes affectent-ils la cicatrisation ?\nQuelles sont les complications des traitements immunosuppresseurs ?\nQuels effets secondaires des médicaments sur les granulocytes ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Granulocytes",
"description": "Quels facteurs augmentent le risque d'infections ?\nQuel rôle des maladies auto-immunes ?\nComment le tabagisme affecte-t-il les granulocytes ?\nQuels risques liés à l'exposition aux produits chimiques ?\nQuel impact de la génétique sur les granulocytes ?",
"url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=Proline#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une granulocytopénie ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un hémogramme révèle une diminution des granulocytes dans le sang."
}
},
{
"@type": "Question",
"name": "Quels tests pour évaluer les granulocytes ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins comme la numération formule sanguine sont utilisés."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une infection liée aux granulocytes ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, fatigue et inflammation peuvent signaler une infection."
}
},
{
"@type": "Question",
"name": "Comment évaluer la fonction des granulocytes ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de phagocytose et de dégranulation peuvent être réalisés."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la biopsie dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une biopsie médullaire peut aider à évaluer la production de granulocytes."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une carence en granulocytes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections fréquentes, fièvre et fatigue sont des symptômes courants."
}
},
{
"@type": "Question",
"name": "Comment se manifeste une réaction allergique ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éruptions cutanées, démangeaisons et œdème peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une inflammation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Rougeur, chaleur, gonflement et douleur sont des signes d'inflammation."
}
},
{
"@type": "Question",
"name": "Quels signes d'une infection bactérienne ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, frissons et douleur localisée peuvent indiquer une infection."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une leucémie ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, ecchymoses et infections fréquentes peuvent être présents."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections chez les patients à faible granulocytes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène et éviter les foules sont essentiels."
}
},
{
"@type": "Question",
"name": "Quels vaccins sont recommandés ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccins contre la grippe et le pneumocoque sont souvent conseillés."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications liées aux granulocytes ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Surveiller les signes d'infection et consulter rapidement un médecin."
}
},
{
"@type": "Question",
"name": "Quel rôle de l'alimentation dans la prévention ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée renforce le système immunitaire."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour la santé des granulocytes ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de relaxation peuvent aider à réduire le stress."
}
},
{
"@type": "Question",
"name": "Comment traiter une granulocytopénie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des transfusions de granulocytes ou des médicaments stimulants peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels médicaments stimulent les granulocytes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le filgrastim et le pegfilgrastim sont des agents couramment utilisés."
}
},
{
"@type": "Question",
"name": "Comment traiter une infection liée aux granulocytes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antibiotiques sont prescrits pour traiter les infections bactériennes."
}
},
{
"@type": "Question",
"name": "Quel rôle des corticostéroïdes dans le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation et moduler la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quand envisager une greffe de moelle osseuse ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de maladies graves affectant la production de granulocytes."
}
},
{
"@type": "Question",
"name": "Quelles complications d'une granulocytopénie sévère ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections graves, septicémie et complications hémorragiques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels risques d'une leucémie myéloïde ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Risque accru d'infections et de saignements en raison de la production anormale."
}
},
{
"@type": "Question",
"name": "Comment les granulocytes affectent-ils la cicatrisation ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diminution des granulocytes peut retarder la cicatrisation des plaies."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications des traitements immunosuppresseurs ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections opportunistes et cancers peuvent survenir avec ces traitements."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires des médicaments sur les granulocytes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent entraîner une diminution des granulocytes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'infections ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une immunodépression, le diabète et l'âge avancé augmentent le risque."
}
},
{
"@type": "Question",
"name": "Quel rôle des maladies auto-immunes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner une destruction accrue des granulocytes."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme affecte-t-il les granulocytes ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme peut altérer la fonction des granulocytes et augmenter l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels risques liés à l'exposition aux produits chimiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains produits chimiques peuvent endommager la moelle osseuse et réduire les granulocytes."
}
},
{
"@type": "Question",
"name": "Quel impact de la génétique sur les granulocytes ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des prédispositions génétiques peuvent influencer la production et la fonction des granulocytes."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 17/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, University Hospital Regensburg, Raubling, Germany.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmacology, University of Bern, Bern, Switzerland; email: thomas.kaufmann@pki.unibe.ch, hans-uwe.simon@pki.unibe.ch.
Department of Clinical Immunology and Allergology, Sechenov University, Moscow, Russia.
Laboratory of Molecular Immunology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Brandenburg Medical School, Neuruppin, Germany.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China. Electronic address: zhangju@mail.ccmu.edu.cn.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Immunology, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Laboratory Medicine, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Immunology, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Cayuga Medical Center, 101 Dates Drive, Ithaca, NY 14850, USA; Weill Cornell Medicine. Electronic address: dmac92077@gmail.com.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Cayuga Medical Center, 101 Dates Drive, Ithaca, NY 14850, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Comparative Pathobiology, Tufts University, Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA. Electronic address: rnolenw@upenn.edu.
Publications dans "Granulocytes" :
The extracellular cellular matrix (ECM) maintains tissue structure and regulates signaling functions by continuous degradation and remodeling. Inflammation or other disease conditions activate proteas...
D-proline and N-boc-5-hydroxy-L-proline are key chiral intermediates in the production of eletriptan and saxagliptin, respectively. An efficient proline racemase-proline dehydrogenase cascade was deve...
Clostridioides difficile is a nosocomial pathogen that colonizes the gut and causes diarrhea, colitis, and severe inflammation. Recently, C. difficile has been shown to use toxin-mediated inflammation...
The entrance of chromium (Cr) into the agricultural system would exert a negative influence on the carbon/nitrogen metabolism (CNM) of plants. In this study, we investigated the role of exogenous prol...
We employed density functional theory (DFT) methods to investigate the most plausible mechanism of cyclization/ring expansion of proline with...
Amino acids in the bone marrow microenvironment (BMME) are a critical factor for multiple myeloma (MM) progression. Here, we have determined that proline is elevated in BMME of MM patients and links t...
Proline residues within proteins lack a traditional hydrogen bond donor. However, the hydrogens of the proline ring are all sterically accessible, with polarized C-H bonds at Hα and Hδ that exhibit gr...
Maillard reaction products obtained from the model system of binary amino acids (asparagine and proline) with glucose were first studied. GC-MS results showed that proline-specific aromatic compounds,...
The protective effects of L-aspartic acid, L-valine, and L-proline on the stability of mulberry anthocyanins were investigated. Results showed that L-aspartic acid, L-valine, and L-proline significant...