Modeling Alzheimer's disease (AD) using human-induced pluripotent stem cells (iPSCs) is a field now spanning 15 years. Developments in the field have shown a shift in using simple 2D cortical neuron m...
Stroke is a life-threatening condition with many complications. Sleep disturbances is one of them. Sleep disturbances effect quality of life, recovery and rehabilitation process. It is crucial to reve...
After translation and culture validation of the scale was done, Pittsburgh Sleep Quality Index (PSQI) and the Turkish version of the GSDS was applied at admission and at 24 h to the 58 patients with s...
Cronbach alpha coefficient of total score was found as 0.850 and test re-test reliability-related Cronbach alpha coefficient was 0.785....
GSDS-T is a reliable and valid tool to assess sleep disturbance in stroke patients....
A new element for job stress called Illegitimate Tasks has been investigated in recent years, along with stress as an offense to self-theory. Illegitimate tasks are those that are either needless or u...
This study aimed to adapt the Bern Illegitimate Tasks Scale to Portuguese and provide evidence of its validity, through a confirmatory factor analysis with a sample of 472 workers from different secto...
The internal consistency, of the whole scale, measured by Cronbach's alpha, was 0.923 and 0.902 and 0.928 for the unnecessary tasks and, for unreasonable tasks subscales respectively. The confirmatory...
The Portuguese version of the Bern Illegitimate Tasks Scale presents very good psychometric properties for the intended measurement goals and can now be used in research with Portuguese speaking sampl...
Mental workload (MWL) is a relevant construct involved in all cognitively demanding activities, and its assessment is an important goal in many research fields. This paper aims at evaluating the repro...
Thirteen young healthy adults were enrolled and were asked to perform 45 min of Simon's task to elicit a cognitive demand. EEG data were collected using a 32-channel system with different electrode co...
MWL assessed with different PPPs showed reliability ranging from good to very good in most of the electrode configurations (average consistency > 0.87 and average absolute agreement > 0.92). Larger fr...
The most complex PPPs have been proven to ensure good reliability (>0.90) and sensitivity in all experimental conditions. In conclusion, we propose to use at least a two-electrode configuration (Fz an...
Chronic viral hepatitis (CH) is a stage prior to cirrhosis and primary cancer. Standard protocols for CH assessment during the long follow-up period are of great importance for precise treatment and l...
Total 503 lines of laboratory data from 2012 to 2021 were extracted from103 CHB patients who were followed-up in our hospital. They were divided into the remission group and the progression group acco...
The models revealed that abundant serum alpha-fetoprotein (AFP) in the remission group was characteristically associated with hepatocyte destruction markers aspartate aminotransferase (AST) and alanin...
This study clearly demonstrates the intrinsic quantitative relationship between serum AFP and liver aminotransferases involving antivirus treatment response. The model-based equation compensates for s...
The chest-related electronic patient reported outcome (ePRO) diary was recently developed to assess chest-related symptoms experienced by pediatric and adolescent populations during upper respiratory ...
This non-interventional, psychometric validation study involved participants (N = 195; n = 42 6-8 years; n = 47 9-11 years; n = 55 12-17 years, n = 51 18+ years) completing the chest-related ePRO diar...
The measure demonstrated strong quality of completion and showed relatively similar trajectories of symptom scores over time within different age subgroups and good item response distribution properti...
The findings demonstrate that the chest-related ePRO diary provides a valid, reliable, responsive measure of chest congestion symptoms experienced with the common cold in pediatric and adolescent popu...
A capillary zone electrophoretic (CZE) method was developed, validated, and applied for the assay of metformin (MET) and pioglitazone (PIO) in pharmaceutical formulations. The optimum running buffer c...
Quantitative and qualitative procedures are necessary components of instrument development and assessment. However, validation studies conventionally emphasise quantitative assessments while neglectin...
We employ a convergent parallel mixed methods design to analyse quantitative and qualitative questionnaire data. Data were collected from staff, supervisors, and patients of a university hospital and ...
Questionnaires from 435 staff, 133 supervisors, and 189 patients were collected. Analysis of congruence potentially provides explanations why respondents' comments are off topic. Convergence between q...
Mixed methods provide alternative means of collecting construct validity evidence. Our suggested procedures can be easily applied on empirical data and allow the congruence, convergence, and credibili...
Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diag...
This was a historical cohort study nationwide with 30 centers in China between January 2000 and December 2019. Clinical data, including age, histology, method of myometrial invasion evaluation (MRI, C...
Among the 490 patients, 89.59% presented myometrial invasion. The methods reported for myometrial invasion assessment were IFS in 23.47%, IGE in 69.59%, MRI in 37.96%, and CT in 10.20% of cases. The h...
In China, the assessment of myometrial invasion in non-endometrioid endometrial carcinoma is often performed via IGE, but the reliability is relatively low in contrast to IFS. In clinical practice, IF...
The sensitive determination of food-borne pathogens from food products is essential to ensure food safety and to protect people's health. Herein, a novel photoelectrochemical (PEC) aptasensor was manu...
