questionsmedicales.fr
Maladies du système immunitaire
Hypersensibilité
Hypersensibilité retardée
Hypersensibilité retardée : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hypersensibilité retardée
Tests cutanés
Tests de patch
Lymphocytes T
Éruption cutanée
Réaction allergique
Analyse sanguine
Inflammation
Antécédents médicaux
Allergènes
Symptômes
5
Éruption cutanée
Démangeaisons
Réaction retardée
Allergène
Symptômes systémiques
Fatigue
Réaction cutanée
Vésicules
Variabilité des symptômes
Réaction individuelle
Prévention
5
Tests d'allergie
Prévention des réactions
Changements de mode de vie
Allergènes alimentaires
Antihistaminiques
Prévention
Gestion des allergies
Médicaments d'urgence
Traitements
5
Corticostéroïdes
Évitement des allergènes
Antihistaminiques
Démangeaisons
Corticostéroïdes
Inflammation
Traitements topiques
Pommades corticostéroïdes
Traitement pédiatrique
Hypersensibilité
Complications
5
Infections cutanées
Complications
Maladies chroniques
Réactions répétées
Anaphylaxie
Réactions sévères
Qualité de vie
Démangeaisons
Hospitalisation
Traitement intensif
Facteurs de risque
5
Facteurs de risque
Antécédents d'allergies
Professions à risque
Produits chimiques
Antécédents familiaux
Allergies
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"name": "Comment diagnostiquer l'hypersensibilité retardée ?",
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"text": "Le diagnostic repose sur l'historique médical et des tests cutanés spécifiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de patch et les tests de stimulation lymphocytaire sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une hypersensibilité retardée ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des éruptions cutanées, démangeaisons et rougeurs apparaissent après exposition à l'allergène."
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"@type": "Question",
"name": "Peut-on diagnostiquer par des analyses sanguines ?",
"position": 4,
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"@type": "Question",
"name": "Quel rôle joue l'historique médical dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
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"text": "L'historique médical aide à identifier les allergènes potentiels et les antécédents d'exposition."
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"@type": "Question",
"name": "Quels sont les symptômes courants ?",
"position": 6,
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"@type": "Question",
"name": "Les symptômes apparaissent-ils immédiatement ?",
"position": 7,
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"text": "Non, ils apparaissent généralement 24 à 72 heures après l'exposition à l'allergène."
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"@type": "Question",
"name": "Y a-t-il des symptômes systémiques ?",
"position": 8,
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"text": "Des symptômes systémiques comme la fièvre ou la fatigue peuvent survenir dans certains cas."
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"name": "Comment se manifeste une réaction cutanée ?",
"position": 9,
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"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, l'intensité et la nature des symptômes peuvent varier selon les individus."
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{
"@type": "Question",
"name": "Comment prévenir l'hypersensibilité retardée ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'exposition aux allergènes connus est la meilleure méthode de prévention."
}
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"@type": "Question",
"name": "Les tests d'allergie aident-ils à la prévention ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests d'allergie peuvent identifier les allergènes à éviter pour prévenir les réactions."
}
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{
"@type": "Question",
"name": "Les changements de mode de vie sont-ils nécessaires ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des changements de mode de vie, comme éviter certains aliments ou produits, peuvent être nécessaires."
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"@type": "Question",
"name": "Les médicaments préventifs sont-ils disponibles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antihistaminiques peuvent être pris en prévention avant une exposition connue."
}
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"@type": "Question",
"name": "Comment gérer les expositions accidentelles ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Avoir un plan d'action et des médicaments d'urgence peut aider à gérer les expositions accidentelles."
}
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"@type": "Question",
"name": "Quel est le traitement principal de l'hypersensibilité retardée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement principal consiste en l'évitement de l'allergène et l'utilisation de corticostéroïdes."
}
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{
"@type": "Question",
"name": "Les antihistaminiques sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antihistaminiques peuvent soulager les démangeaisons, mais ne traitent pas la cause."
}
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{
"@type": "Question",
"name": "Comment les corticostéroïdes aident-ils ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes réduisent l'inflammation et soulagent les symptômes cutanés."
}
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{
"@type": "Question",
"name": "Y a-t-il des traitements topiques recommandés ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des crèmes ou pommades corticostéroïdes peuvent être appliquées sur les zones affectées."
}
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"@type": "Question",
"name": "Les traitements sont-ils différents pour les enfants ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction de l'âge et de la gravité des symptômes."
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des infections cutanées peuvent survenir si les lésions sont grattées."
}
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"@type": "Question",
"name": "L'hypersensibilité retardée peut-elle entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des réactions répétées peuvent contribuer à des maladies cutanées chroniques."
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"@type": "Question",
"name": "Y a-t-il un risque d'anaphylaxie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'anaphylaxie est rare dans l'hypersensibilité retardée, mais des réactions sévères peuvent survenir."
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"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent entraîner des douleurs, des démangeaisons et une gêne sociale."
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"@type": "Question",
"name": "Les complications nécessitent-elles une hospitalisation ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas graves, une hospitalisation peut être nécessaire pour un traitement intensif."
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"@type": "Question",
"name": "Quels sont les facteurs de risque principaux ?",
"position": 26,
"acceptedAnswer": {
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"text": "Les antécédents d'allergies, l'exposition répétée et la génétique sont des facteurs de risque."
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"@type": "Question",
"name": "L'âge influence-t-il le risque d'hypersensibilité ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les jeunes enfants et les personnes âgées peuvent être plus à risque."
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"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut exacerber les symptômes et augmenter la sensibilité aux allergènes."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un historique familial d'allergies peut augmenter le risque d'hypersensibilité retardée."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 30/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Elizabeth.j.phillips@vumc.org.
Publications dans "Hypersensibilité retardée" :
3 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, No.155, Sec.2, Linong Street, Taipei, 112 Taiwan. Electronic address: sihung@cgmh.org.tw.
Publications dans "Hypersensibilité retardée" :
3 publications dans cette catégorie
Affiliations :
Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia.
Clinical Immunology and Allergy, McGill University Health Center, Montréal, Canada.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, No. 123, Xiafei Road, Haicang District, Xiamen, China.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, No. 123, Xiafei Road, Haicang District, Xiamen, China; Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Maijin Rd., Anle Dist., Keelung 204, Taiwan; College of Medicine, Chang Gung University, No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan 333, Taiwan. Electronic address: chung1@cgmh.org.tw.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
IRCCS Oasi Maria S.S., Troina, Italy.
Fondazione Mediterranea G.B. Morgagni, Italy.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
département de Dermatologie et Allergologie, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP.Sorbonne Université, Hôpital Tenon, Paris F75020, France. Electronic address: annick.barbaud@aphp.fr.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Faculty of Health Sciences, Universidad Europea de Valencia, 46010 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Faculty of Health Sciences, Universidad Europea de Valencia, 46010 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Pharmacy Unit, University General Hospital Consortium, 46014 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Research and Teaching Unit, University General Hospital Consortium, 46014 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Infectious Diseases, Austin Health, Center for Antibiotic Allergy and Research, Heidelberg, VIC, Australia.
Department of Oncology, Sir Peter MacCallum Cancer Center, The University of Melbourne, Parkville, VIC, Australia.
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, VIC, Australia.
The National Center for Infections in Cancer, Peter MacCallum Cancer Center, Melbourne, VIC, Australia.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Allergy, Zhongnan Hospital of Wuhan University, Wuhan, China.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Department of Immunology, Hospital de la Princesa, Health Research Institute of Princesa Hospital (ISS-IP), Autonomous University of Madrid, 28006 Madrid, Spain.
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Werner Siemens Imaging Center, Department of Preclinical Imaging and RadiopharmacyEberhard Karls University, 72076 Tübingen, Germany.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Eberhard Karls University, 72076 Tübingen, Germany.
Publications dans "Hypersensibilité retardée" :
Ameloblastoma is the most common odontogenic tumour and its histomorphological distinction into growth patterns and variants, does not accurately convey information about its biologic aggressiveness. ...
This is a retrospective study conducted to evaluate the immunoprofile of selected clinical subtypes and histological variants to EMT factors via immunostaining to SLUG and ECAD/NCAD antibodies. Mean a...
A higher staining SLUG intensity in the stellate reticulum (SR) like areas relative to the ameloblast like areas (AR) was observed, without concomitant E-cadherin repression or elimination. However, a...
Expression of SLUG in the SR like areas can be utilized to predict the biologic behavior of specific clinico-histological variants, however its mechanism via alterations in cadherin switching is equiv...
Cadherins are a family of cell surface glycoproteins that mediate Ca...
N-cadherin-mediated cell adhesion is a vital inductor for mesenchymal condensation in chondrogenesis. Recent studies have revealed the involvement of E-cadherin in enhancing the multipotency of mesenc...
This study aimed to explore the synergistic modulation of E/N-cadherin in the chondrogenic differentiation of MSC aggregates....
Human E/N-cadherin-functionalized (hE/N-cad-Fc) poly (lactic-co-glycolic acid) (PLGA) microparticles (hE/N-cad-PLGA) were incorporated into the human MSC (hMSC) aggregates to upregulate the expression...
A total of 1083 DEGs, comprising 111 upregulated and 972 downregulated genes, were discovered to be related to the enhanced chondrogenic differentiation modulated by hE/N-cad-Fc. The GO and KEGG funct...
To the best of our knowledge, our study is the first to reveal that the synergistic modulation of E/N-cadherin enhances the chondrogenic differentiation of hMSCs via the ERK1/2-p53 signaling axis....
Cell adhesion systems commonly operate in close partnership with the cytoskeleton. Adhesion receptors bind to the cortex and regulate its dynamics, organization and mechanics; conversely, the cytoskel...
Reduced or null expression of E-cadherin protein is a frequent cause of diffuse gastric cancer (DGC). More than 50% of patients with DGC present somatic variants in...
The objectives of this study were to study E-cadherin expression and identify variants in the...
We studied 18 Mexican DGC patients who attended a hospital of the Mexican Social Security Institute; E-cadherin expression was determined by immunohistochemistry, and variants were identified by Sange...
We found that 56% of DGC patients showed reduced expression of E-cadherin. All patients carried...
In this Mexican population, the percentage of diffuse gastric tumors with reduced expression of E-cadherin was similar to that reported in other populations. All gastric tumors of DGC patients studied...
The engagement of cadherins, cell-to-cell adhesion proteins, triggers a dramatic increase in the levels and activity of the Rac/Cdc42 GTPases, through the inhibition of proteasomal degradation. This l...
Invasive lobular carcinoma exhibits unique morphological features frequently associated with alterations in...
The formation of a centralised apical membrane initiation site (AMIS) is a key event in epithelial cell polarisation. A recent study by Liang et al demonstrates that AMIS localisation relies on cadher...
Cadherins mediate cell-cell adhesion and help the cell determine its shape and function. Here we study collective cadherin organization and interactions within cell-cell contact areas, and find the ca...
Cadherins are essential cell-cell adhesion proteins that interact in two distinct conformations: X-dimers and strand-swap dimers. Both X-dimers and strand-swap dimers are thought to exclusively rely o...