questionsmedicales.fr
Malformations et maladies congénitales, héréditaires et néonatales
Malformations
Malformations du système stomatognathique
Malformations de la bouche
Malformations de la bouche : Questions médicales fréquentes
Termes MeSH sélectionnés :
STAT3 Transcription Factor
Diagnostic
5
Anomalies Congénitales
Diagnostic Médical
Imagerie Médicale
Anomalies Congénitales
Anomalies Congénitales
Nouveau-né
Échographie
Anomalies Congénitales
Chirurgie Maxillo-Faciale
Orthodontie
Symptômes
5
Symptômes
Anomalies Congénitales
Douleur
Anomalies Congénitales
Infection
Anomalies Congénitales
Troubles de la Parole
Anomalies Congénitales
Anomalies Dentaires
Anomalies Congénitales
Prévention
5
Prévention
Soins Prénatals
Acide Folique
Prévention des Malformations
Vaccination
Prévention des Malformations
Facteurs Environnementaux
Anomalies Congénitales
Traitements
5
Chirurgie
Soins Conservateurs
Traitement Précoce
Anomalies Congénitales
Soins Post-Opératoires
Douleur
Efficacité du Traitement
Anomalies Congénitales
Complications
5
Nutrition
Anomalies Congénitales
Santé Mentale
Anomalies Congénitales
Croissance
Anomalies Congénitales
Complications à Long Terme
Anomalies Dentaires
Facteurs de risque
5
Facteurs de Risque
Anomalies Congénitales
Âge Maternel
Anomalies Congénitales
Médicaments
Anomalies Congénitales
Infections
Anomalies Congénitales
Nutrition
Anomalies Congénitales
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"name": "Les malformations affectent-elles la parole ?",
"position": 9,
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"text": "Oui, elles peuvent entraîner des troubles de la parole en raison de la position des organes buccaux."
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"@type": "Question",
"name": "Peut-on observer des malformations dentaires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des malformations de la bouche peuvent également entraîner des anomalies dentaires."
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"@type": "Question",
"name": "Peut-on prévenir les malformations de la bouche ?",
"position": 11,
"acceptedAnswer": {
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"text": "Certaines malformations peuvent être prévenues par une bonne nutrition et des soins prénatals."
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"@type": "Question",
"name": "Quel rôle joue l'acide folique dans la prévention ?",
"position": 12,
"acceptedAnswer": {
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"text": "L'acide folique réduit le risque de malformations congénitales, y compris buccales."
}
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"@type": "Question",
"name": "Les habitudes maternelles influencent-elles ces malformations ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes comme le tabagisme ou l'alcoolisme pendant la grossesse augmentent les risques."
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"@type": "Question",
"name": "Les vaccinations maternelles sont-elles importantes ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, certaines vaccinations peuvent réduire le risque de malformations congénitales."
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"name": "Les facteurs environnementaux jouent-ils un rôle ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, l'exposition à des toxines environnementales peut augmenter le risque de malformations."
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"name": "Quels traitements sont disponibles pour ces malformations ?",
"position": 16,
"acceptedAnswer": {
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"text": "Les traitements incluent la chirurgie, l'orthodontie et la thérapie de la parole."
}
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{
"@type": "Question",
"name": "La chirurgie est-elle toujours nécessaire ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pas toujours, certaines malformations peuvent être gérées par des soins conservateurs."
}
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{
"@type": "Question",
"name": "À quel âge peut-on traiter ces malformations ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut commencer dès la naissance ou être planifié selon la gravité."
}
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"@type": "Question",
"name": "Y a-t-il des soins post-opératoires spécifiques ?",
"position": 19,
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"name": "Les traitements sont-ils efficaces ?",
"position": 20,
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"name": "Quelles complications peuvent survenir après un traitement ?",
"position": 21,
"acceptedAnswer": {
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"text": "Des complications peuvent inclure des infections, des cicatrices ou des problèmes fonctionnels."
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"name": "Les malformations de la bouche entraînent-elles des problèmes nutritionnels ?",
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"text": "Oui, elles peuvent causer des difficultés à manger, entraînant des carences nutritionnelles."
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"name": "Y a-t-il des risques psychologiques associés ?",
"position": 23,
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"text": "Oui, les malformations peuvent entraîner des problèmes d'estime de soi et d'anxiété sociale."
}
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"@type": "Question",
"name": "Les malformations peuvent-elles affecter la croissance ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des difficultés alimentaires peuvent impacter la croissance et le développement global."
}
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"@type": "Question",
"name": "Quelles sont les complications à long terme possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications à long terme incluent des problèmes dentaires, de parole et d'estime de soi."
}
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{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour ces malformations ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des maladies maternelles et des habitudes de vie."
}
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{
"@type": "Question",
"name": "L'âge maternel influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes de plus de 35 ans ont un risque accru de malformations congénitales."
}
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"@type": "Question",
"name": "Les médicaments pendant la grossesse sont-ils un risque ?",
"position": 28,
"acceptedAnswer": {
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"text": "Oui, certains médicaments peuvent augmenter le risque de malformations buccales."
}
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"@type": "Question",
"name": "Les infections maternelles peuvent-elles affecter le fœtus ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines infections comme la rubéole peuvent causer des malformations congénitales."
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"@type": "Question",
"name": "L'alimentation maternelle joue-t-elle un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation pauvre en nutriments peut augmenter le risque de malformations."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 02/05/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Publications dans "Malformations de la bouche" :
2 publications dans cette catégorie
Publications dans "Malformations de la bouche" :
2 publications dans cette catégorie
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
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1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
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Children's Hospital of Nanjing Medical University, Nanjing, China. Electronic address: medtronic@163.com.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
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Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China. Electronic address: guowei1205@cpu.edu.cn.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Radiology, Graduate School of Medicine, The University of Tokyo.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Radiology, Graduate School of Medicine, The University of Tokyo.
Division of Neuroradiology, Department of Radiology, University of Michigan.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Radiology, Graduate School of Medicine, The University of Tokyo.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Radiology, Graduate School of Medicine, The University of Tokyo.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
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Department of Oral Diagnostic Sciences, Nihon University School of Dentistry.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Oral Diagnostic Sciences, Nihon University School of Dentistry.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Oral and Maxillofacial Radiology, Nihon University School of Dentistry.
Publications dans "Malformations de la bouche" :
1 publication dans cette catégorie
Affiliations :
Department of Radiology, Graduate School of Medicine, The University of Tokyo.
Publications dans "Malformations de la bouche" :
Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that promotes cell proliferation and immunomodulation in untransformed cells and maintains stemness of t...
Although previously reported as an activating mutation, the STAT3-D427H mutant neither showed elevated cytokine-induced tyrosine phosphorylation nor altered nuclear accumulation, as compared to the WT...
Based on our data, it is unlikely that the D427H missense mutation in the STAT3 protein possesses an oncogenic potential beyond the WT molecule....
Cancer cells inevitably develop radioresistance during lung adenocarcinoma radiotherapy. However, the mechanisms are incompletely clarified. In this study, we show that FIBP protein expression in lung...
The continuous activation of transcription factors drives many diseases, including tumors, autoimmune disease, neurodegenerative disease, and male infertility. Thus, Blocking the transcriptional activ...
Fusing the transcriptional inhibitory domain KRAB with STAT3 successfully blocked the transcription activity of STAT3 in cancer cells without affecting its function in the mitochondria and lysosomes....
the expression of KRAB-STAT3 fusion protein inhibited the growth of tumor cells....
The KRAB-STAT3 fusion protein provides a novel approach for drug development for the treatment of cancer or autoimmune diseases....
The transcription factor STAT3 is a potent activator of transcription, but evidence exists that STAT3 can also repress gene expression. However, little is known about the molecular mechanisms involved...
To investigate hypoxia-induced Nestin regulates lung cancer viability and metabolism by targeting transcription factors Nrf2, STAT3, and SOX2....
Eighty-four cases of nonsmall cell lung cancer (nonsmall cell lung cancer, NSCLC), which had been treated from June 2020 to February 2021, were randomly selected from our clinicopathology database. Im...
Clinicopathological findings showed significant differences in lymph node metastasis, tissue differentiation, and histology on induction of Nestin expression; Nestin expression correlated with STAT3, ...
Hypoxia-induced Nestin promotes the progression of nonsmall lung cancer cells by targeting the downstream transcription factors STAT3, Nrf2, and SOX2....
Medulloblastoma is the most common malignant brain tumor of childhood accounting for about 60% of all pediatric embryonal tumors. Despite improvements in the overall survival rate, this tumor still la...
To explore the expression of frizzled related protein (FRZB) in triple-negative breast cancer (TNBC) and role of FRZB in TNBC cell growth and invasion....
Breast cancer clinical data were downloaded from the Cancer Genome Atlas. FRZB and early growth response 1 (EGR1) mRNA levels in TNBC were measured by quantitative real-time polymerase chain reaction....
FRZB was low expressed in TNBC tissues and cells. Silencing FRZB promoted cell proliferation, migration, invasion, and EMT and activated JAK/STAT pathway in MDA-MB-468 and MDA-MB-231 cells, but overex...
FRZB was low expressed in TNBC and was regulated by EGR1, and FRZB inhibited TNBC cell growth and invasion by regulating the JAK/STAT3 pathway....
Precision medicine and customized therapeutics based on the features of each patient are important for maximizing therapeutic effects. Because most cases of HCC occur in the damaged liver through vari...
Using HBV infection models and gene knockout cells, we determined the crucial signaling axis responsible for the effects of cabozantinib on HBV. A chromatin immunoprecipitation assay was performed to ...
Cabozantinib inhibited HBV replication through the HGF-mesenchymal-epithelial transition factor-signal transducer and activator of transcription 3 (MET-STAT3) signaling axis. The importance of STAT3 i...
Cabozantinib has favorable therapeutic effects on HBV-related HCC because it inhibits HCC not only directly but also indirectly by means of inhibitory effects on HBV....
The constitutive activation and aberrant expression of Signal Transducer and Activator of Transcription 3 (STAT3) plays a key role in initiation and progression of cervical cancer (CaCx). How STAT3 in...
CMTR1, also called IFN-stimulated gene 95 kDa protein (ISG95), is elevated by viral infection in a variety of cells. However, the functions of CMTR1 in colorectal cancer (CRC), especially its roles in...