Mitochondrial Factors in the Cell Nucleus.
The origin of eukaryotic organisms involved the integration of mitochondria into the ancestor cell, with a massive gene transfer from the original proteobacterium to the host nucleus. Thus, mitochondr...
Activité de type insulinique non suppressible : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer l'activité insulinique non suppressible ?
Des tests sanguins mesurant les niveaux d'insuline et de glucose sont effectués.
#2
Quels tests sont utilisés pour évaluer cette condition ?
Le test de tolérance au glucose et les dosages d'insuline sont courants.
#3
Quels signes cliniques indiquent cette activité ?
Des symptômes comme l'hyperglycémie persistante peuvent être observés.
#4
L'imagerie est-elle utile pour le diagnostic ?
L'imagerie n'est généralement pas utilisée pour cette condition spécifique.
#5
Peut-on utiliser des biomarqueurs pour le diagnostic ?
Oui, des biomarqueurs comme le peptide C peuvent aider à évaluer l'insulinémie.
Symptômes 5
#1
Quels sont les symptômes courants de cette condition ?
Les symptômes incluent fatigue, soif excessive et besoin fréquent d'uriner.
#2
L'hypoglycémie est-elle un symptôme possible ?
Oui, des épisodes d'hypoglycémie peuvent survenir malgré une insulinémie élevée.
#3
Y a-t-il des symptômes liés à la prise de poids ?
Oui, une prise de poids inexpliquée peut être un symptôme associé.
#4
Les troubles de la vision sont-ils possibles ?
Oui, des troubles visuels peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Des symptômes cutanés peuvent-ils apparaître ?
Oui, des infections cutanées fréquentes peuvent être un signe d'insulinorésistance.
Prévention 5
#1
Comment prévenir l'activité insulinique non suppressible ?
Maintenir un poids santé et adopter un mode de vie actif sont essentiels.
#2
L'alimentation joue-t-elle un rôle préventif ?
Oui, une alimentation équilibrée peut réduire le risque de résistance à l'insuline.
#3
Le dépistage précoce est-il important ?
Oui, le dépistage régulier peut aider à identifier les problèmes tôt.
#4
Le stress influence-t-il cette condition ?
Oui, le stress peut aggraver la résistance à l'insuline et les symptômes.
#5
Les habitudes de sommeil affectent-elles la prévention ?
Oui, un sommeil de qualité est crucial pour la régulation de l'insuline.
Traitements 5
#1
Quels traitements sont disponibles pour cette condition ?
Les traitements incluent des médicaments antidiabétiques et des modifications du mode de vie.
#2
L'insuline est-elle utilisée dans le traitement ?
Oui, l'insuline peut être administrée pour contrôler les niveaux de glucose.
#3
Les changements alimentaires sont-ils recommandés ?
Oui, un régime équilibré et pauvre en glucides est souvent conseillé.
#4
La thérapie physique peut-elle aider ?
Oui, l'exercice régulier peut améliorer la sensibilité à l'insuline.
#5
Des traitements alternatifs existent-ils ?
Certaines approches comme la médecine complémentaire peuvent être explorées.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications comme le diabète de type 2 et des maladies cardiovasculaires peuvent se développer.
#2
L'insulinorésistance peut-elle entraîner des complications ?
Oui, l'insulinorésistance est liée à des complications métaboliques graves.
#3
Des problèmes rénaux peuvent-ils se développer ?
Oui, des maladies rénales chroniques peuvent être une complication de cette condition.
#4
Les troubles neurologiques sont-ils possibles ?
Oui, des neuropathies peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Y a-t-il un risque accru de maladies cardiaques ?
Oui, le risque de maladies cardiaques est significativement augmenté.
Facteurs de risque 5
#1
Quels sont les principaux facteurs de risque ?
L'obésité, le manque d'exercice et des antécédents familiaux sont des facteurs clés.
#2
L'âge influence-t-il le risque ?
Oui, le risque augmente avec l'âge, surtout après 45 ans.
#3
Le tabagisme est-il un facteur de risque ?
Oui, le tabagisme est associé à une augmentation de la résistance à l'insuline.
#4
Les antécédents médicaux jouent-ils un rôle ?
Oui, des antécédents de diabète gestationnel augmentent le risque futur.
#5
Le stress chronique est-il un facteur de risque ?
Oui, le stress chronique peut contribuer à l'insulinorésistance.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Jie Li
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Xiao-Chen Bai
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
- Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Eunhee Choi
4 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA. EC3477@cumc.columbia.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Catherine Hall
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Jiayi Wu
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Junhee Park
2 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Christopher T V Swain
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Ann E Drummond
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Roger L Milne
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Dallas R English
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Kristy A Brown
2 publications dans cette catégorie
Affiliations :
- Department of Medicine, Weill Cornell Medicine, New York, New York.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tina L Skinner
2 publications dans cette catégorie
Affiliations :
- The University of Queensland, School of Human Movement and Nutrition Sciences, St. Lucia, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Eline H van Roekel
2 publications dans cette catégorie
Affiliations :
- Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Melissa M Moore
2 publications dans cette catégorie
Affiliations :
- Medical Oncology, St. Vincent's Hospital, Melbourne, Australia.
- Department of Medicine, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tom R Gaunt
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Richard M Martin
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
- IHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Sarah J Lewis
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Brigid M Lynch
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Physical Activity Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Carlie Delaine
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Briony E Forbes
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Sources (10000 au total)
The Material Properties of the Cell Nucleus: A Matter of Scale.
Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules. The nucleus contains macromole...
Comparison of cell type distribution between single-cell and single-nucleus RNA sequencing: enrichment of adherent cell types in single-nucleus RNA sequencing.
Single-cell ribonucleic acid (RNA) sequencing (scRNA-seq) is an effective technique for estimating the cellular composition and transcriptional profiles of individual cells from fresh tissue. Single-n...
Measurement of the Compressibility of Cell and Nucleus Based on Acoustofluidic Microdevice.
Cell mechanics play an important role in tumor metastasis, malignant transformation of cells, and radiosensitivity. During these processes, studying the mechanical properties of the cells is often cha...
ANNEXIN A1: Roles in Placenta, Cell Survival, and Nucleus.
The unbiased approaches of the last decade have enabled the collection of new data on the biology of annexin A1 (ANXA1) in a variety of scientific aspects, creating opportunities for new biomarkers an...
Nucleus size and its effect on nucleosome stability in living cells.
DNA architectural proteins play a major role in organization of chromosomal DNA in living cells by packaging it into chromatin, whose spatial conformation is determined by an intricate interplay betwe...
Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.
The HIV-1 genome encodes a small number of proteins with structural, enzymatic, regulatory, and accessory functions. These viral proteins interact with a number of host factors to promote the early an...
Live Cell Imaging Reveals HBV Capsid Translocation from the Nucleus To the Cytoplasm Enabled by Cell Division.
Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress pathway. To better define sites of HBV capsi...
Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast.
Cells actively position their nuclei based on their activity. In fission yeast, microtubule-dependent nuclear centering is critical for symmetrical cell division. After spindle disassembly at the end ...
The dual role of FSP1 in programmed cell death: resisting ferroptosis in the cell membrane and promoting necroptosis in the nucleus of THP-1 cells.
Acute monocytic leukemia-M5 (AML-M5) remains a challenging disease due to its high morbidity and poor prognosis. In addition to the evidence mentioned earlier, several studies have shown that programm... THP-1 cells were mainly treated with Erastin and IMP-366. The changes of ferroptosis and necroptosis levels were detected by CCK-8, western blot, quantitative real-time PCR, and electron microscopy. F... The addition of the myristoylation inhibitor IMP-366 to erastin-treated acute monocytic leukemia cell line THP-1 cell not only resulted in greater susceptibility to ferroptosis characterized by lipid ... We demonstrated that inhibition of myristoylation by IMP-366 is capable of switching ferroptosis and ferroptosis-dependent necroptosis in THP-1 cells. In these findings, FSP1-mediated ferroptosis and ...