Molecular dynamics simulation study on
EngA, a GTPase contains two GTP binding domains [GD1, GD2], and the C-terminal KH domain shown to be involved in the later stages of ribosome maturation. Association of EngA to the ribosomal subunit i...
Activité de type insulinique non suppressible : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer l'activité insulinique non suppressible ?
Des tests sanguins mesurant les niveaux d'insuline et de glucose sont effectués.
#2
Quels tests sont utilisés pour évaluer cette condition ?
Le test de tolérance au glucose et les dosages d'insuline sont courants.
#3
Quels signes cliniques indiquent cette activité ?
Des symptômes comme l'hyperglycémie persistante peuvent être observés.
#4
L'imagerie est-elle utile pour le diagnostic ?
L'imagerie n'est généralement pas utilisée pour cette condition spécifique.
#5
Peut-on utiliser des biomarqueurs pour le diagnostic ?
Oui, des biomarqueurs comme le peptide C peuvent aider à évaluer l'insulinémie.
Symptômes 5
#1
Quels sont les symptômes courants de cette condition ?
Les symptômes incluent fatigue, soif excessive et besoin fréquent d'uriner.
#2
L'hypoglycémie est-elle un symptôme possible ?
Oui, des épisodes d'hypoglycémie peuvent survenir malgré une insulinémie élevée.
#3
Y a-t-il des symptômes liés à la prise de poids ?
Oui, une prise de poids inexpliquée peut être un symptôme associé.
#4
Les troubles de la vision sont-ils possibles ?
Oui, des troubles visuels peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Des symptômes cutanés peuvent-ils apparaître ?
Oui, des infections cutanées fréquentes peuvent être un signe d'insulinorésistance.
Prévention 5
#1
Comment prévenir l'activité insulinique non suppressible ?
Maintenir un poids santé et adopter un mode de vie actif sont essentiels.
#2
L'alimentation joue-t-elle un rôle préventif ?
Oui, une alimentation équilibrée peut réduire le risque de résistance à l'insuline.
#3
Le dépistage précoce est-il important ?
Oui, le dépistage régulier peut aider à identifier les problèmes tôt.
#4
Le stress influence-t-il cette condition ?
Oui, le stress peut aggraver la résistance à l'insuline et les symptômes.
#5
Les habitudes de sommeil affectent-elles la prévention ?
Oui, un sommeil de qualité est crucial pour la régulation de l'insuline.
Traitements 5
#1
Quels traitements sont disponibles pour cette condition ?
Les traitements incluent des médicaments antidiabétiques et des modifications du mode de vie.
#2
L'insuline est-elle utilisée dans le traitement ?
Oui, l'insuline peut être administrée pour contrôler les niveaux de glucose.
#3
Les changements alimentaires sont-ils recommandés ?
Oui, un régime équilibré et pauvre en glucides est souvent conseillé.
#4
La thérapie physique peut-elle aider ?
Oui, l'exercice régulier peut améliorer la sensibilité à l'insuline.
#5
Des traitements alternatifs existent-ils ?
Certaines approches comme la médecine complémentaire peuvent être explorées.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications comme le diabète de type 2 et des maladies cardiovasculaires peuvent se développer.
#2
L'insulinorésistance peut-elle entraîner des complications ?
Oui, l'insulinorésistance est liée à des complications métaboliques graves.
#3
Des problèmes rénaux peuvent-ils se développer ?
Oui, des maladies rénales chroniques peuvent être une complication de cette condition.
#4
Les troubles neurologiques sont-ils possibles ?
Oui, des neuropathies peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Y a-t-il un risque accru de maladies cardiaques ?
Oui, le risque de maladies cardiaques est significativement augmenté.
Facteurs de risque 5
#1
Quels sont les principaux facteurs de risque ?
L'obésité, le manque d'exercice et des antécédents familiaux sont des facteurs clés.
#2
L'âge influence-t-il le risque ?
Oui, le risque augmente avec l'âge, surtout après 45 ans.
#3
Le tabagisme est-il un facteur de risque ?
Oui, le tabagisme est associé à une augmentation de la résistance à l'insuline.
#4
Les antécédents médicaux jouent-ils un rôle ?
Oui, des antécédents de diabète gestationnel augmentent le risque futur.
#5
Le stress chronique est-il un facteur de risque ?
Oui, le stress chronique peut contribuer à l'insulinorésistance.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Jie Li
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Xiao-Chen Bai
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
- Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Eunhee Choi
4 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA. EC3477@cumc.columbia.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Catherine Hall
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Jiayi Wu
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Junhee Park
2 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Christopher T V Swain
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Ann E Drummond
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Roger L Milne
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Dallas R English
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Kristy A Brown
2 publications dans cette catégorie
Affiliations :
- Department of Medicine, Weill Cornell Medicine, New York, New York.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tina L Skinner
2 publications dans cette catégorie
Affiliations :
- The University of Queensland, School of Human Movement and Nutrition Sciences, St. Lucia, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Eline H van Roekel
2 publications dans cette catégorie
Affiliations :
- Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Melissa M Moore
2 publications dans cette catégorie
Affiliations :
- Medical Oncology, St. Vincent's Hospital, Melbourne, Australia.
- Department of Medicine, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tom R Gaunt
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Richard M Martin
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
- IHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Sarah J Lewis
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Brigid M Lynch
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Physical Activity Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Carlie Delaine
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Briony E Forbes
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Sources (10000 au total)
Molecular dynamics simulation of ssDNA and cationic polythiophene.
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Residence Times from Molecular Dynamics Simulations.
In this work, efficient methods are proposed for the calculation, from molecular dynamics trajectories, of residence times (RTs) and related quantities. One of these was designed to obtain RT distribu...
Accelerators for Classical Molecular Dynamics Simulations of Biomolecules.
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Molecular Dynamics Simulations of Different Nanoparticles at Substrates.
We report the results of large-scale molecular dynamics simulations of adsorption nanoparticles on solid surfaces. The particles were modeled as stiff aggregates of spherical segments. Three types of ...
Reactive Molecular Dynamics Simulations of Polystyrene Pyrolysis.
Polymers' controlled pyrolysis is an economical and environmentally friendly solution to prepare activated carbon. However, due to the experimental difficulty in measuring the dependence between micro...
Molecular Dynamics Simulations of Deformable Viral Capsomers.
Most coarse-grained models of individual capsomers associated with viruses employ rigid building blocks that do not exhibit shape adaptation during self-assembly. We develop a coarse-grained general m...
Molecular-dynamics simulation methods for macromolecular crystallography.
It is investigated whether molecular-dynamics (MD) simulations can be used to enhance macromolecular crystallography (MX) studies. Historically, protein crystal structures have been described using a ...
Molecular Dynamics Simulation Prediction of the Partitioning Constants (
The tendency of organic contaminants (OCs) to partition between different phases is a key set of properties that underlie their human and ecological health impacts and the success of remediation effor...
Molecular dynamics simulations for the study of chromatin biology.
The organization of Eukaryotic DNA into chromatin has profound implications for the processing of genetic information. In the past years, molecular dynamics (MD) simulations proved to be a powerful to...