Nom anglais: Protein-Arginine N-Methyltransferases
Descriptor UI:D011484
Tree Number:D08.811.913.555.500.800.750
Termes MeSH sélectionnés :
Accelerometry
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"name": "Diagnostic",
"headline": "Diagnostic sur Protein-arginine N-methyltransferases",
"description": "Comment diagnostiquer une dysfonction des N-méthyltransférases ?\nQuels tests sont utilisés pour évaluer l'activité enzymatique ?\nY a-t-il des biomarqueurs associés à ces enzymes ?\nQuels symptômes peuvent indiquer un problème enzymatique ?\nComment les tests génétiques aident-ils au diagnostic ?",
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"description": "Quels sont les symptômes d'une carence en N-méthyltransférases ?\nLes troubles de l'humeur sont-ils liés à ces enzymes ?\nPeut-on observer des symptômes neurologiques ?\nY a-t-il des symptômes spécifiques chez les enfants ?\nComment les symptômes varient-ils selon l'âge ?",
"url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Accelerometry&page=3#section-symptômes"
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"description": "Comment prévenir les troubles liés aux N-méthyltransférases ?\nY a-t-il des mesures préventives spécifiques ?\nL'éducation sur la santé est-elle importante ?\nLes vaccinations jouent-elles un rôle préventif ?\nComment le suivi médical aide-t-il à la prévention ?",
"url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Accelerometry&page=3#section-prévention"
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"description": "Quels traitements existent pour les dysfonctionnements enzymatiques ?\nLes médicaments peuvent-ils aider à réguler ces enzymes ?\nY a-t-il des thérapies géniques disponibles ?\nComment la nutrition influence-t-elle le traitement ?\nLes traitements sont-ils personnalisés ?",
"url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Accelerometry&page=3#section-traitements"
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"description": "Quelles complications peuvent survenir avec ces troubles ?\nLes troubles cardiovasculaires sont-ils possibles ?\nComment les complications affectent-elles la qualité de vie ?\nY a-t-il des complications à long terme ?\nLes complications peuvent-elles être évitées ?",
"url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Accelerometry&page=3#section-complications"
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"headline": "Facteurs de risque sur Protein-arginine N-methyltransferases",
"description": "Quels sont les facteurs de risque associés ?\nL'environnement joue-t-il un rôle ?\nLe mode de vie affecte-t-il le risque ?\nLes infections peuvent-elles être un facteur de risque ?\nY a-t-il des groupes à risque spécifiques ?",
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction des N-méthyltransférases ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses biochimiques peuvent être utilisés pour diagnostiquer."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'activité enzymatique ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests enzymatiques spécifiques mesurent l'activité des N-méthyltransférases dans les échantillons."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à ces enzymes ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des biomarqueurs comme la méthylation de l'arginine peuvent indiquer une activité enzymatique."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème enzymatique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes variés comme des troubles neurologiques ou immunitaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment les tests génétiques aident-ils au diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils identifient des mutations spécifiques dans les gènes codant pour ces enzymes."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une carence en N-méthyltransférases ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, troubles cognitifs et anomalies immunitaires."
}
},
{
"@type": "Question",
"name": "Les troubles de l'humeur sont-ils liés à ces enzymes ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres peuvent affecter l'humeur et contribuer à des troubles psychiatriques."
}
},
{
"@type": "Question",
"name": "Peut-on observer des symptômes neurologiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles neurologiques comme des convulsions peuvent être présents."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques chez les enfants ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les enfants peuvent présenter des retards de développement et des troubles d'apprentissage."
}
},
{
"@type": "Question",
"name": "Comment les symptômes varient-ils selon l'âge ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent être plus prononcés chez les jeunes enfants et les personnes âgées."
}
},
{
"@type": "Question",
"name": "Comment prévenir les troubles liés aux N-méthyltransférases ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir ces troubles."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages précoces et des conseils génétiques peuvent être bénéfiques."
}
},
{
"@type": "Question",
"name": "L'éducation sur la santé est-elle importante ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, sensibiliser les patients et les familles peut aider à identifier les symptômes tôt."
}
},
{
"@type": "Question",
"name": "Les vaccinations jouent-elles un rôle préventif ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les symptômes."
}
},
{
"@type": "Question",
"name": "Comment le suivi médical aide-t-il à la prévention ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier permet de surveiller l'état de santé et d'ajuster les traitements."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour les dysfonctionnements enzymatiques ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent inclure des suppléments nutritionnels et des thérapies ciblées."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider à réguler ces enzymes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent moduler l'activité des N-méthyltransférases."
}
},
{
"@type": "Question",
"name": "Y a-t-il des thérapies géniques disponibles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours sur les thérapies géniques pour corriger les mutations."
}
},
{
"@type": "Question",
"name": "Comment la nutrition influence-t-elle le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en nutriments peut soutenir la fonction enzymatique."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction des besoins individuels du patient."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec ces troubles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications neurologiques, immunitaires et métaboliques peuvent se développer."
}
},
{
"@type": "Question",
"name": "Les troubles cardiovasculaires sont-ils possibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres peuvent augmenter le risque de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des limitations fonctionnelles et des besoins de soins accrus."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications chroniques peuvent affecter la santé globale et le bien-être."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être évitées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être évitées par un traitement précoce et approprié."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque associés ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des mutations génétiques et des carences nutritionnelles."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux comme la pollution peuvent influencer la fonction enzymatique."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sédentaire et une mauvaise alimentation augmentent le risque de troubles."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent exacerber les symptômes et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Y a-t-il des groupes à risque spécifiques ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes avec des antécédents familiaux ou des troubles métaboliques sont plus à risque."
}
}
]
}
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Given the evolution of processing and analysis methods for accelerometry data over the past decade, it is important to understand how newer summary measures of physical activity compare with establish...
We aimed to compare objective measures of physical activity to increase the generalizability and translation of findings of studies that use accelerometry-based data....
High-resolution accelerometry data from the Baltimore Longitudinal Study on Aging were retrospectively analyzed. Data from 655 participants who used a wrist-worn ActiGraph GT9X device continuously for...
Data were from a sample (N=655; male: n=298, 45.5%; female: n=357, 54.5%) with a mean age of 69.8 years (SD 14.2) and mean BMI of 27.3 kg/m2 (SD 5.0). The mean marginal participant-specific correlatio...
The findings from this comparison of accelerometry-based measures of physical activity can be used by researchers and facilitate the extension of knowledge from existing literature by demonstrating th...
Accurately measuring energy expenditure during physical activity outside of the laboratory is challenging, especially on a large scale. Thigh-worn accelerometers have gained popularity due to the poss...
We first trained a supervised deep learning activity classification model using pooled data from available adult accelerometer datasets. The composite energy expenditure model was then developed and v...
The activity classification model showed an overall accuracy of 99.7% across all five activity types during validation. The composite model for estimating energy expenditure achieved a mean absolute p...
The integration of thigh-worn accelerometers with machine learning models provides a highly accurate method for classifying physical activity types and estimating energy expenditure. Our novel composi...
Too much sedentary behavior (SB) and too little physical activity (PA) place adult workers at risk for chronic illness. It remains unclear which occupations and subgroups within occupations have the h...
A literature search of six databases was performed for relevant studies published through March 2023. Eligible studies were in English, targeted working populations, had a sample size > 75, and object...
We found that 63% of the studies reported daily time spent in SB and in MVPA, but fewer reported LPA, moderate PA, and vigorous PA. The average time spent in SB was 553.34 min/day, in LPA was 299.77 m...
More research is needed to explore SB and PA patterns within occupational subgroups. Additionally, it is important to explore work-related individual (e.g., job task), interpersonal (e.g., social supp...
Hip-worn triaxial accelerometers are widely used to assess physical activity in terms of energy expenditure. Methods for classification in terms of different types of activity of relevance to the skel...
Inertial signals are the most widely used signals in human activity recognition (HAR) applications, and extensive research has been performed on developing HAR classifiers using accelerometer and gyro...
The purpose of this descriptive cross-sectional study is to describe the amount and intensity of physical activity (PA) measured by accelerometry among adolescents participating in organized sports (S...
Perri, T, Reid, M, Murphy, A, Howle, K, and Duffield, R. Determining stroke and movement profiles in competitive tennis match-play from wearable sensor accelerometry. J Strength Cond Res 37(6): 1271-1...
Physical activity is deemed critical to successful ageing. Despite evidence and progress, there is still a need to determine more precisely the direction, magnitude, intensity, and volume of physical ...
Few studies have examined accelerometer-measured physical activity and incident breast cancer (BC). Thus, this study examined associations between accelerometer-measured vector magnitude counts per 15...
The WHAC comprised 21,089 postmenopausal women (15,375 from the Women's Health Study [WHS]; 5714 from the Women's Health Initiative Objective Physical Activity and Cardiovascular Health Study [OPACH])...
In covariate-adjusted models, the highest (vs. lowest) tertiles of VM/15s, TPA, LPA, and MVPA were associated with BC HRs of 0.80 (95% CI, 0.64-0.99), 0.84 (95% CI, 0.69-1.02), 0.89 (95% CI, 0.73-1.08...
Greater levels of accelerometer-assessed PA were associated with lower BC risk. Associations varied by age and obesity and were not independent of BMI or physical function....
People with cerebral palsy (CP) often have difficulties related to maintaining body balance in their daily living activities. Accelerometers are low-cost wearable devices with potential use to objecti...
What are the main characteristics and findings from protocols used in research aiming to investigate standing or dynamic body balance stability through trunk accelerometry in people with CP?...
We searched in December 2021 seven databases, Pubmed, Embase, Cochrane, Science Direct, Scopus, PEDro, and Lilacs, with descriptors related to cerebral palsy, accelerometer, and balance....
Ten studies were included, with a total of 197 evaluated people with CP. These studies were classified as moderate or high methodological quality. We found convergence on the use of the sensor at the ...
Trunk accelerometry in quiet posture and dynamic tasks was shown to be a valid and sensitive measurement to evaluate balance stability in children and adolescents with CP. It is a small, light, low-co...
