Titre : Uridine diphosphate

Uridine diphosphate : Questions médicales fréquentes

Termes MeSH sélectionnés :

Intestinal Failure
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Uridine diphosphate : Questions médicales les plus fréquentes", "headline": "Uridine diphosphate : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Uridine diphosphate : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-22", "dateModified": "2025-04-18", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Uridine diphosphate" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Nucléotides uridyliques", "url": "https://questionsmedicales.fr/mesh/D014500", "about": { "@type": "MedicalCondition", "name": "Nucléotides uridyliques", "code": { "@type": "MedicalCode", "code": "D014500", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Uridine diphosphate ose", "alternateName": "Uridine Diphosphate Sugars", "url": "https://questionsmedicales.fr/mesh/D014539", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate ose", "code": { "@type": "MedicalCode", "code": "D014539", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Uridine diphosphate N-acétylgalactosamine", "alternateName": "Uridine Diphosphate N-Acetylgalactosamine", "url": "https://questionsmedicales.fr/mesh/D014536", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate N-acétylgalactosamine", "code": { "@type": "MedicalCode", "code": "D014536", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.100" } } }, { "@type": "MedicalWebPage", "name": "Uridine diphosphate N-acétylglucosamine", "alternateName": "Uridine Diphosphate N-Acetylglucosamine", "url": "https://questionsmedicales.fr/mesh/D014537", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate N-acétylglucosamine", "code": { "@type": "MedicalCode", "code": "D014537", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.120" } } }, { "@type": "MedicalWebPage", "name": "Acide uridine diphosphate N-acétylmuramique", "alternateName": "Uridine Diphosphate N-Acetylmuramic Acid", "url": "https://questionsmedicales.fr/mesh/D014538", "about": { "@type": "MedicalCondition", "name": "Acide uridine diphosphate N-acétylmuramique", "code": { "@type": "MedicalCode", "code": "D014538", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.150" } } }, { "@type": "MedicalWebPage", "name": "Uridine diphosphate galactose", "alternateName": "Uridine Diphosphate Galactose", "url": "https://questionsmedicales.fr/mesh/D014531", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate galactose", "code": { "@type": "MedicalCode", "code": "D014531", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.300" } } }, { "@type": "MedicalWebPage", "name": "Uridine diphosphate glucose", "alternateName": "Uridine Diphosphate Glucose", "url": "https://questionsmedicales.fr/mesh/D014532", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate glucose", "code": { "@type": "MedicalCode", "code": "D014532", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.350" } } }, { "@type": "MedicalWebPage", "name": "Acide uridine diphosphate glucuronique", "alternateName": "Uridine Diphosphate Glucuronic Acid", "url": "https://questionsmedicales.fr/mesh/D014535", "about": { "@type": "MedicalCondition", "name": "Acide uridine diphosphate glucuronique", "code": { "@type": "MedicalCode", "code": "D014535", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.375" } } }, { "@type": "MedicalWebPage", "name": "Uridine diphosphate xylose", "alternateName": "Uridine Diphosphate Xylose", "url": "https://questionsmedicales.fr/mesh/D014540", "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate xylose", "code": { "@type": "MedicalCode", "code": "D014540", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D13.695.827.919.600.677.800" } } } ] } ], "about": { "@type": "MedicalCondition", "name": "Uridine diphosphate", "alternateName": "Uridine Diphosphate", "code": { "@type": "MedicalCode", "code": "D014530", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Takayuki Matsumoto", "url": "https://questionsmedicales.fr/author/Takayuki%20Matsumoto", "affiliation": { "@type": "Organization", "name": "Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan. Electronic address: t-matsu@hoshi.ac.jp." } }, { "@type": "Person", "name": "Kumiko Taguchi", "url": "https://questionsmedicales.fr/author/Kumiko%20Taguchi", "affiliation": { "@type": "Organization", "name": "Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan." } }, { "@type": "Person", "name": "Tsuneo Kobayashi", "url": "https://questionsmedicales.fr/author/Tsuneo%20Kobayashi", "affiliation": { "@type": "Organization", "name": "Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan. Electronic address: tkoba@hoshi.ac.jp." } }, { "@type": "Person", "name": "Rafal Jonczyk", "url": "https://questionsmedicales.fr/author/Rafal%20Jonczyk", "affiliation": { "@type": "Organization", "name": "Biotechnology of Natural Products, Technische Universität München, 85354 Freising, Germany." } }, { "@type": "Person", "name": "Thomas Hoffmann", "url": "https://questionsmedicales.fr/author/Thomas%20Hoffmann", "affiliation": { "@type": "Organization", "name": "Biotechnology of Natural Products, Technische Universität München, 85354 Freising, Germany." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Central venous catheter safety in pediatric patients with intestinal failure.", "datePublished": "2023-08-03", "url": "https://questionsmedicales.fr/article/37537891", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/ncp.11047" } }, { "@type": "ScholarlyArticle", "name": "ESPEN guideline on chronic intestinal failure in adults - Update 2023.", "datePublished": "2023-07-29", "url": "https://questionsmedicales.fr/article/37639741", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.clnu.2023.07.019" } }, { "@type": "ScholarlyArticle", "name": "Assessment of body composition in pediatric intestinal failure: A comparison study.", "datePublished": "2023-07-17", "url": "https://questionsmedicales.fr/article/37355855", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/jpen.2540" } }, { "@type": "ScholarlyArticle", "name": "Development of a core outcome set for pediatric chronic intestinal failure.", "datePublished": "2023-01-08", "url": "https://questionsmedicales.fr/article/36546585", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/jpen.2468" } }, { "@type": "ScholarlyArticle", "name": "Characteristics of adult intestinal failure centers: An international multicenter survey.", "datePublished": "2022-10-29", "url": "https://questionsmedicales.fr/article/36309481", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/ncp.10926" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Acides nucléiques, nucléotides et nucléosides", "item": "https://questionsmedicales.fr/mesh/D009706" }, { "@type": "ListItem", "position": 3, "name": "Nucléotides", "item": "https://questionsmedicales.fr/mesh/D009711" }, { "@type": "ListItem", "position": 4, "name": "Ribonucléotides", "item": "https://questionsmedicales.fr/mesh/D012265" }, { "@type": "ListItem", "position": 5, "name": "Nucléotides uridyliques", "item": "https://questionsmedicales.fr/mesh/D014500" }, { "@type": "ListItem", "position": 6, "name": "Uridine diphosphate", "item": "https://questionsmedicales.fr/mesh/D014530" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Uridine diphosphate - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Uridine diphosphate", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-12", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Uridine diphosphate", "description": "Comment diagnostiquer une carence en UDP ?\nQuels tests sont utilisés pour évaluer l'UDP ?\nL'UDP peut-il être mesuré dans le sang ?\nQuels symptômes indiquent un problème d'UDP ?\nY a-t-il des marqueurs spécifiques pour l'UDP ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Uridine diphosphate", "description": "Quels sont les symptômes d'une carence en UDP ?\nL'UDP affecte-t-il le système nerveux ?\nDes douleurs musculaires peuvent-elles être liées à l'UDP ?\nL'UDP influence-t-il l'humeur ?\nY a-t-il des signes cutanés associés à l'UDP ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Uridine diphosphate", "description": "Comment prévenir une carence en UDP ?\nLes suppléments sont-ils nécessaires pour l'UDP ?\nY a-t-il des groupes à risque pour l'UDP ?\nLes habitudes de vie influencent-elles l'UDP ?\nDes conseils nutritionnels existent-ils pour l'UDP ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Uridine diphosphate", "description": "Comment traiter une carence en UDP ?\nLes médicaments peuvent-ils aider à l'UDP ?\nY a-t-il des thérapies alternatives pour l'UDP ?\nLes changements alimentaires sont-ils efficaces ?\nDes traitements spécifiques existent-ils pour l'UDP ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Uridine diphosphate", "description": "Quelles complications peuvent survenir avec une carence en UDP ?\nL'UDP peut-il affecter le développement ?\nDes maladies chroniques sont-elles liées à l'UDP ?\nL'UDP est-il impliqué dans des maladies héréditaires ?\nDes troubles immunitaires peuvent-ils être liés à l'UDP ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Uridine diphosphate", "description": "Quels sont les facteurs de risque pour l'UDP ?\nL'âge influence-t-il les niveaux d'UDP ?\nLe stress peut-il affecter l'UDP ?\nLes maladies génétiques influencent-elles l'UDP ?\nLes habitudes alimentaires jouent-elles un rôle ?", "url": "https://questionsmedicales.fr/mesh/D014530?mesh_terms=Intestinal+Failure&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une carence en UDP ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests biochimiques mesurant les niveaux d'UDP dans les cellules peuvent être effectués." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'UDP ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests enzymatiques et chromatographiques sont couramment utilisés pour évaluer l'UDP." } }, { "@type": "Question", "name": "L'UDP peut-il être mesuré dans le sang ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "L'UDP est généralement mesuré dans les tissus plutôt que dans le sang en raison de sa faible concentration." } }, { "@type": "Question", "name": "Quels symptômes indiquent un problème d'UDP ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme la fatigue, des troubles neurologiques ou des anomalies métaboliques peuvent survenir." } }, { "@type": "Question", "name": "Y a-t-il des marqueurs spécifiques pour l'UDP ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de marqueurs spécifiques, mais des niveaux d'enzymes peuvent indiquer des anomalies." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une carence en UDP ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, faiblesse musculaire et troubles cognitifs." } }, { "@type": "Question", "name": "L'UDP affecte-t-il le système nerveux ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une carence en UDP peut entraîner des troubles neurologiques et cognitifs." } }, { "@type": "Question", "name": "Des douleurs musculaires peuvent-elles être liées à l'UDP ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des douleurs musculaires peuvent survenir en raison d'un métabolisme énergétique altéré." } }, { "@type": "Question", "name": "L'UDP influence-t-il l'humeur ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Une carence en UDP peut affecter l'humeur et entraîner des troubles de l'humeur." } }, { "@type": "Question", "name": "Y a-t-il des signes cutanés associés à l'UDP ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des anomalies cutanées peuvent apparaître, mais elles sont moins fréquentes." } }, { "@type": "Question", "name": "Comment prévenir une carence en UDP ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée riche en acides nucléiques peut aider à prévenir une carence." } }, { "@type": "Question", "name": "Les suppléments sont-ils nécessaires pour l'UDP ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Les suppléments peuvent être bénéfiques, surtout en cas de régime alimentaire pauvre." } }, { "@type": "Question", "name": "Y a-t-il des groupes à risque pour l'UDP ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes ayant des troubles métaboliques ou des régimes restrictifs sont à risque." } }, { "@type": "Question", "name": "Les habitudes de vie influencent-elles l'UDP ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes de vie saines, comme l'exercice, peuvent soutenir le métabolisme de l'UDP." } }, { "@type": "Question", "name": "Des conseils nutritionnels existent-ils pour l'UDP ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, consulter un nutritionniste peut aider à élaborer un plan alimentaire adapté." } }, { "@type": "Question", "name": "Comment traiter une carence en UDP ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut inclure des suppléments d'uridine et des modifications alimentaires." } }, { "@type": "Question", "name": "Les médicaments peuvent-ils aider à l'UDP ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Certains médicaments peuvent améliorer le métabolisme de l'UDP, mais nécessitent une prescription." } }, { "@type": "Question", "name": "Y a-t-il des thérapies alternatives pour l'UDP ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des thérapies comme la nutrition ciblée peuvent être bénéfiques, mais nécessitent des études." } }, { "@type": "Question", "name": "Les changements alimentaires sont-ils efficaces ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en acides nucléiques peut aider à augmenter les niveaux d'UDP." } }, { "@type": "Question", "name": "Des traitements spécifiques existent-ils pour l'UDP ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de traitements spécifiques approuvés pour les troubles liés à l'UDP." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec une carence en UDP ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications neurologiques et métaboliques peuvent survenir si non traitées." } }, { "@type": "Question", "name": "L'UDP peut-il affecter le développement ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une carence en UDP peut nuire au développement cognitif et physique chez les enfants." } }, { "@type": "Question", "name": "Des maladies chroniques sont-elles liées à l'UDP ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies métaboliques chroniques peuvent être exacerbées par une carence en UDP." } }, { "@type": "Question", "name": "L'UDP est-il impliqué dans des maladies héréditaires ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles héréditaires du métabolisme peuvent affecter les niveaux d'UDP." } }, { "@type": "Question", "name": "Des troubles immunitaires peuvent-ils être liés à l'UDP ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Une carence en UDP peut affaiblir le système immunitaire, augmentant le risque d'infections." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour l'UDP ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les régimes alimentaires pauvres, les maladies métaboliques et le stress sont des facteurs de risque." } }, { "@type": "Question", "name": "L'âge influence-t-il les niveaux d'UDP ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les niveaux d'UDP peuvent diminuer avec l'âge, augmentant le risque de carence." } }, { "@type": "Question", "name": "Le stress peut-il affecter l'UDP ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut perturber le métabolisme de l'UDP et entraîner des carences." } }, { "@type": "Question", "name": "Les maladies génétiques influencent-elles l'UDP ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies génétiques peuvent affecter la synthèse et l'utilisation de l'UDP." } }, { "@type": "Question", "name": "Les habitudes alimentaires jouent-elles un rôle ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation déséquilibrée peut augmenter le risque de carence en UDP." } } ] } ] }

Sources (10000 au total)

ESPEN guideline on chronic intestinal failure in adults - Update 2023.

In 2016, ESPEN published the guideline for Chronic Intestinal Failure (CIF) in adults. An updated version of ESPEN guidelines on CIF due to benign disease in adults was devised in order to incorporate... The grading system of the Scottish Intercollegiate Guidelines Network (SIGN) was used to grade the literature. Recommendations were graded according to the levels of evidence available as A (strong), ... The recommendations of the 2016 guideline were reviewed, particularly focusing on definitions, and new chapters were included to devise recommendations on IF centers, chronic enterocutaneous fistulas,... It is confirmed that CIF management requires complex technologies, multidisciplinary and multiprofessional activity, and expertise to care for the underlying gastrointestinal disease and to provide HP...

Assessment of body composition in pediatric intestinal failure: A comparison study.

The objective of the study was to compare bioelectrical impedance analysis (BIA) and skinfolds with dual energy x-ray absorptiometry (DXA) in the assessment of body composition of children with intest... Children aged 1-18 years with intestinal failure whohave DXA as part of routine clinical monitoring were eligible. BIA measured total body water on the same day as DXA. Skinfold measurements were take... Sixty-eight children with intestinal failure, mean age 8.9 ± 4.2 years, were studied. There was no difference between %FFM and %FM obtained by DXA and BIA (P = 0.26), with a mean bias (95% CI) of -0.6... BIA is an acceptable clinical tool for assessing body composition in pediatric intestinal failure....

Development of a core outcome set for pediatric chronic intestinal failure.

In research on pediatric chronic intestinal failure, heterogeneity in reported definitions and outcomes exists. This leads to a risk of reporting bias and impossibility of evidence synthesis. Also, re... Candidate outcomes were selected from a recent systematic review. A three-round Delphi study among key stakeholders and a consensus meeting with an expert panel were undertaken to achieve consensus on... Seventy-two stakeholders (79%) completed all three rounds of the Delphi process. Ninety-eight outcomes were assessed, and five new outcomes were added after the first round. Ten outcomes were included... This pediatric chronic intestinal failure COS consists of 10 outcomes important for all key stakeholders. Usage of this set in future research should minimize outcome heterogeneity and enhance the val...

Characteristics of adult intestinal failure centers: An international multicenter survey.

Current guidelines recommend that patients with chronic intestinal failure (CIF) should be managed by a multidisciplinary team (MDT). However, the characteristics of real-world IF centers and the pati... This is an international multicenter study of adult IF centers using a survey. The questionnaire survey included questions regarding program and patient characteristics. Thirty-three investigational c... The survey center response rate was 91%. The median number of patients with CIF per center was 128 (range, 30-380). The most common disciplines reported were gastroenterologist (93%), dietitian (90%),... The majority of centers were managing around 100 patients with CIF. Despite the widespread use of the MDT, there are some variances in team characteristics. Gastroenterologists were the most common ph...

High Rate of Venous Thromboembolism in Severe Pediatric Intestinal Failure.

To quantify the rate of venous thromboembolism (VTE) in patients with pediatric intestinal failure and identify associated risk factors.... We performed a retrospective cohort study in pediatric patients (<21 years old) with severe pediatric intestinal failure (≥90 consecutive days of parenteral nutrition) secondary to short bowel syndrom... A total of 263 patients (59.7% male) met the criteria for inclusion. The cumulative incidence of VTE was 28.1%, with a rate of 0.32 VTEs per 1000 catheter-days. On univariate analysis, the number of c... In this retrospective study, 28.1% of patients with severe pediatric intestinal failure developed VTE; the number of catheters and early gestational age were noted to be independent risk factors for V...

Pitfalls of iron supplementation in parenteral nutrition admixtures for children with intestinal failure.

Pediatric patients with intestinal failure are at increased risk for iron deficiency. Supplementation is not routinely included in parenteral nutrition solutions. There is currently limited research r... We review a patient case and the current available literature related to iron in parenteral nutrition.... Five major concerns are identified: peroxidation reactions, incompatibility, hypersensitivity, infection risk, and iron overload.... We propose an argument against the preferential use of iron supplementation within parenteral nutrition in children with intestinal failure when enteral supplementation or intermittent parenteral infu...

Chronic Mucosal Inflammation in Pediatric Intestinal Failure Patients-A Unique Phenomenon.

As intestinal failure (IF) management improves and long-term survival rate increases, its physiological complications have become more apparent. The development of chronic intestinal inflammation rese... This retrospective study was based on the electronic medical records of pediatric patients seen at the Cincinnati Children's Hospital Medical Center between January 2000 and July 2022. Demographic and... During the follow-up period, 23 children were diagnosed with chronic intestinal inflammation. Of these, 12 (52%) were males, with a median age of 4.5 (3-7) years at diagnosis. Nearly one-third of the ... SBS patients are at risk of relatively early onset chronic intestinal inflammation. The absence of an ICV (and adjoin ileum) and prior lengthening procedures emerge as factors associated with the risk...

Nutritional Management of Intestinal Failure due to Short Bowel Syndrome in Children.

The most common cause of intestinal failure (IF) in childhood remains short bowel syndrome (SBS), where bowel mass is significantly reduced due to a congenital atresia or resection and parenteral nutr... A literature search was performed from 1992 to 2022 using Pubmed, MEDLINE and Cochrane Database of Systematic Reviews, and recent guidelines were reviewed. In the absence of evidence, recommendations ... Consensus on the best possible way of feeding children with IF-SBS is lacking and practice varies widely between centres. Feeding should commence as soon as possible following surgery. Oral feeding is... To date, uniform agreement on the optimal type of feed, timing of food introduction and feeding regime used is lacking and great difference in practice remains. There is need for more research to esta...