Titre : Granulomatose avec polyangéite

Granulomatose avec polyangéite : Questions médicales fréquentes

Termes MeSH sélectionnés :

Predictive Value of Tests
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Granulomatose avec polyangéite - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Granulomatose avec polyangéite", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-12", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Granulomatose avec polyangéite", "description": "Comment diagnostiquer la granulomatose avec polyangéite ?\nQuels tests sanguins sont utilisés pour le diagnostic ?\nQuel rôle joue la biopsie dans le diagnostic ?\nQuels symptômes cliniques orientent vers cette maladie ?\nComment les examens d'imagerie aident-ils au diagnostic ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Granulomatose avec polyangéite", "description": "Quels sont les symptômes courants de cette maladie ?\nLa granulomatose affecte-t-elle les voies respiratoires ?\nQuels problèmes rénaux peuvent survenir ?\nY a-t-il des manifestations cutanées ?\nLes symptômes varient-ils d'un patient à l'autre ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Granulomatose avec polyangéite", "description": "Peut-on prévenir la granulomatose avec polyangéite ?\nComment éviter les complications ?\nLes vaccinations sont-elles recommandées ?\nY a-t-il des conseils de mode de vie à suivre ?\nLes patients doivent-ils éviter certains médicaments ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Granulomatose avec polyangéite", "description": "Quels traitements sont utilisés pour cette maladie ?\nComment les corticostéroïdes aident-ils ?\nQuels sont les effets secondaires des traitements ?\nLa thérapie biologique est-elle une option ?\nQuelle est l'importance du suivi médical ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Granulomatose avec polyangéite", "description": "Quelles sont les complications possibles ?\nComment l'insuffisance rénale se manifeste-t-elle ?\nLes infections sont-elles fréquentes ?\nQuels problèmes pulmonaires peuvent survenir ?\nComment gérer les complications ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Granulomatose avec polyangéite", "description": "Quels sont les facteurs de risque connus ?\nLe tabagisme augmente-t-il le risque ?\nLes infections peuvent-elles déclencher la maladie ?\nY a-t-il un lien avec d'autres maladies auto-immunes ?\nL'âge influence-t-il le risque ?", "url": "https://questionsmedicales.fr/mesh/D014890?mesh_terms=Predictive+Value+of+Tests&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer la granulomatose avec polyangéite ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des tests sanguins, des biopsies et des examens d'imagerie." } }, { "@type": "Question", "name": "Quels tests sanguins sont utilisés pour le diagnostic ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent la recherche d'anticorps anti-PR3 et des marqueurs d'inflammation." } }, { "@type": "Question", "name": "Quel rôle joue la biopsie dans le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "La biopsie permet d'identifier les granulomes et l'inflammation des vaisseaux." } }, { "@type": "Question", "name": "Quels symptômes cliniques orientent vers cette maladie ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des douleurs articulaires, des éruptions cutanées et des problèmes respiratoires." } }, { "@type": "Question", "name": "Comment les examens d'imagerie aident-ils au diagnostic ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les examens comme la radiographie ou l'IRM montrent des anomalies dans les poumons et les reins." } }, { "@type": "Question", "name": "Quels sont les symptômes courants de cette maladie ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, fièvre, perte de poids, et douleurs musculaires." } }, { "@type": "Question", "name": "La granulomatose affecte-t-elle les voies respiratoires ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut provoquer des sinusites, des saignements de nez et des toux persistantes." } }, { "@type": "Question", "name": "Quels problèmes rénaux peuvent survenir ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des atteintes rénales peuvent entraîner une insuffisance rénale et des urines anormales." } }, { "@type": "Question", "name": "Y a-t-il des manifestations cutanées ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des éruptions cutanées, des nodules et des ulcères peuvent apparaître." } }, { "@type": "Question", "name": "Les symptômes varient-ils d'un patient à l'autre ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'intensité et la combinaison des symptômes peuvent varier considérablement." } }, { "@type": "Question", "name": "Peut-on prévenir la granulomatose avec polyangéite ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de méthode de prévention spécifique, mais un suivi médical peut aider." } }, { "@type": "Question", "name": "Comment éviter les complications ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Un traitement précoce et un suivi régulier permettent de réduire le risque de complications." } }, { "@type": "Question", "name": "Les vaccinations sont-elles recommandées ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les vaccinations peuvent être recommandées pour prévenir certaines infections." } }, { "@type": "Question", "name": "Y a-t-il des conseils de mode de vie à suivre ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, est conseillé." } }, { "@type": "Question", "name": "Les patients doivent-ils éviter certains médicaments ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments peuvent aggraver la maladie et doivent être évités." } }, { "@type": "Question", "name": "Quels traitements sont utilisés pour cette maladie ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des corticostéroïdes et des immunosuppresseurs pour réduire l'inflammation." } }, { "@type": "Question", "name": "Comment les corticostéroïdes aident-ils ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Ils réduisent l'inflammation et soulagent les symptômes rapidement." } }, { "@type": "Question", "name": "Quels sont les effets secondaires des traitements ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires peuvent inclure des infections, des troubles digestifs et des problèmes osseux." } }, { "@type": "Question", "name": "La thérapie biologique est-elle une option ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des thérapies biologiques ciblées peuvent être utilisées pour les cas réfractaires." } }, { "@type": "Question", "name": "Quelle est l'importance du suivi médical ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi régulier est crucial pour ajuster le traitement et surveiller les complications." } }, { "@type": "Question", "name": "Quelles sont les complications possibles ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent l'insuffisance rénale, les infections et les problèmes pulmonaires." } }, { "@type": "Question", "name": "Comment l'insuffisance rénale se manifeste-t-elle ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Elle peut se manifester par une diminution de la production d'urine et un gonflement." } }, { "@type": "Question", "name": "Les infections sont-elles fréquentes ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les patients sont plus susceptibles de développer des infections en raison du traitement." } }, { "@type": "Question", "name": "Quels problèmes pulmonaires peuvent survenir ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des complications pulmonaires peuvent inclure des hémorragies et des nodules pulmonaires." } }, { "@type": "Question", "name": "Comment gérer les complications ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "La gestion des complications nécessite un suivi médical étroit et des ajustements de traitement." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque connus ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, le tabagisme et certaines infections." } }, { "@type": "Question", "name": "Le tabagisme augmente-t-il le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme est un facteur de risque significatif pour cette maladie." } }, { "@type": "Question", "name": "Les infections peuvent-elles déclencher la maladie ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections, comme celles des voies respiratoires, peuvent être des déclencheurs." } }, { "@type": "Question", "name": "Y a-t-il un lien avec d'autres maladies auto-immunes ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les personnes atteintes d'autres maladies auto-immunes peuvent avoir un risque accru." } }, { "@type": "Question", "name": "L'âge influence-t-il le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "La maladie est plus fréquente chez les adultes jeunes à moyens, généralement entre 30 et 60 ans." } } ] } ] }

Sources (10000 au total)

Value of faecal exfoliated cells in colorectal tumour screening using SDC2 methylation test.

This study aimed to evaluate the diagnostic value of a non-invasive methylation gene test in clinical colorectal tumour screening.... The quantitative methylation-specific PCR technique was used to detect faecal methylated syndecan-2 (mSDC2) in patients who received the screening of colorectal cancer (CRC).To evaluate the positive p... The PPV of CRC, CRC + AA and CRN in male patients were 28.03%, 43.55% and 56.24%, respectively, which were higher than female patients. The positive detection rate of mSDC2 and the PPV of CRC graduall... The mSDC2 test has a higher PPV in patients with colorectal cancer and colorectal adenoma (AD), especially in high-risk groups over 50 years of age, and may help in the early diagnosis of colorectal t...

Positive Predictive Value of Diagnosis Codes for Hidradenitis Suppurativa and Cutaneous Abscess.

Requisite to the application of clinical databases for observational research in hidradenitis suppurativa (HS) is the identification of an accurate case cohort. There is limited information on the val... The objective of the study was to assess the validity in utilizing diagnosis codes to establish the HS and CA cohorts from an integrated health system clinical database.... In this retrospective study, we evaluated a case-finding algorithm for HS which included the presence of at least one diagnosis code for HS and no diagnosis codes for CA of the axilla, groin, perineum... Among 100 HS patients, median age (interquartile range) in the HS cohort was 33 (24.75, 43.25) years. HS patients were predominantly female (82%) and white (70%). Median age among 100 CA patients was ... The case-finding algorithms employing at least one diagnosis code for HS and CA of the axilla, groin, perineum, or buttock, with the exclusion of the other's diagnosis codes, has good to strong PPV an...

Positive Predictive Value of Primary Subarachnoid Hemorrhage Diagnoses on Death Certificates.

Epidemiological studies of primary subarachnoid hemorrhage (pSAH) frequently include population-based death registries for case finding. The positive predictive value of pSAH diagnoses in death regist... This cross-sectional study identified all people in Ontario, Canada with pSAH listed as a cause of death between 2013 and 2017. pSAH was classified as "very likely" if diagnosis of pSAH was confirmed ... 1,613 deaths attributed to pSAH were identified (mean 322/year). pSAH classification frequencies were as follows: very likely 528 (32.7%); very unlikely 433 (26.8%); and status unknown 652 (40.4%).... We found that a quarter of pSAH cases in our province's death registry were very unlikely to be true pSAH while 40% had unknown veracity. These data should be considered when using death registries fo...

Negative predictive value of the FebriDx host response point-of-care test in patients presenting to a single Australian emergency department with suspected COVID-19: an observational diagnostic accuracy study.

To determine the negative predictive value (NPV) of the FebriDx point-of-care host response device in patients presenting with symptoms suggestive of COVID-19 infection in a mostly immunised Australia... Observational diagnostic accuracy study comparing FebriDx point-of-care test to SARS-CoV-2 PCR.... An ED in Melbourne, Australia, with 63 000 annual presentations in 2021.... Patients aged 16 and over who met the Victorian Department of Health case definition for suspected COVID-19 infection PCR testing. Patients meeting any of the following criteria were excluded: <16 yea... COVID-19 PCR results (detected, not detected) and FebriDx results (bacterial positive, viral negative, viral positive).... 94 participants were enrolled (female: 46; male: 48), 34% of participants (tested positive for COVID-19 according to PCR results, with a background incidence among all adult ED attenders of 2.5%. The ... In the context of a population with low COVID-19 infection rates, an evolved variant of COVID-19 and a very high community COVID-19 vaccination rate, FebriDx demonstrated reduced sensitivity and NPV r... ACTRN12620001029987 (Australian Clinical Trials)....

Positive Predictive Value of Endoscopic Findings to Diagnose Vocal Fold Paresis.

Laryngoscopy corresponding with laryngeal electromyography (LEMG) is essential in diagnosing vocal fold paresis. However, baseline asymmetry or other diseases oftentimes confound the exam, making diag... We performed a retrospective review of patients with laryngeal asymmetry on laryngoscopy. Patients were divided into two groups: those with consistent paresis triad findings across all pitches and int... Twelve patients met inclusion criteria (age 50 +/-15, 7F:5M). Nine had the paresis triad. Three had an inconsistent triad. All patients with the paresis triad had LEMG findings consistent with neurolo... Our findings suggest the proposed laryngoscopic paresis triad may be useful objective criteria to diagnose paresis without the need for LEMG. Further prospective studies should examine a larger series... 4 Laryngoscope, 133:1712-1716, 2023....

Positive predictive value of humeral fractures in the Danish National Patient Registry.

The purpose of this study was to validate the humeral fracture diagnoses for adults in the Danish National Patient Registry (DNPR).... This was a population-based validity study, including adult patients (≥ 18 years) with a humeral fracture referred to the emergency department of hospitals in three Danish regions from March 2017 to F... In total, 661 patients were sampled between all available diagnosis codes. Overall, the PPV for humeral fracture was 89.3% (95% CI: 86.6-91.4%). PPVs for the subdivision codes were 91.0% (95% CI: 84.0... The validity of the humeral fracture diagnosis and the classifications of proximal and diaphyseal fractures in the DNPR is high, and the DNPR may therefore be used in registry research. Diagnosis of d... none.... not relevant....

Discriminative value of different combinations of tests to detect unilateral neglect in patients with right hemisphere damage.

This study was undertaken to assess the most sensitive combination of tests to detect peripersonal unilateral neglect (UN) after stroke.... The present study is a secondary analysis of a previously reported multicentric study of 203 individuals with right hemisphere damage (RHD), mainly subacute stroke, 11 weeks postonset on average, and ... A combination of four z-scores based on the following three tests provided good discrimination of patients with RHD from matched healthy controls: the starting point and the difference between the num... The most sensitive and parsimonious combination of tests to detect UN after stroke relies on four scores from three simple tests (bells test, line bisection, and reading). Future study is warranted to...