Molecular Biophysics and Structural Biology (MBSB) Group, Department of Biochemistry and Microbiology, University of Zululand KwaDlangezwa 3886, South Africa.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Molecular Biophysics and Structural Biology (MBSB) Group, Department of Biochemistry and Microbiology, University of Zululand KwaDlangezwa 3886, South Africa.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Université de Montréal, Département de Médecine Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger-Pavillon R 900 Saint Denis Street Montreal, Quebec Canada, H2X 0A9, Montréal, Canada.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Université de Montréal, Département de Médecine Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger-Pavillon R 900 Saint Denis Street Montreal, Quebec Canada, H2X 0A9, Montréal, Canada. shao.ling.zhang@umontreal.ca.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Université de Montréal, Département de Médecine Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Tour Viger-Pavillon R 900 Saint Denis Street Montreal, Quebec Canada, H2X 0A9, Montréal, Canada. john.chan@umontreal.ca.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. T.Lashley@ucl.ac.uk.
Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK. T.Lashley@ucl.ac.uk.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Office of the Saskatchewan Multiple Sclerosis Clinical Research Chair, Cameco MS Neuroscience Research Centre, Department of Medicine, Neurology Division, College of Medicine, University of Saskatchewan, Saskatoon, SK S7K 0M7, Canada.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
Office of the Saskatchewan Multiple Sclerosis Clinical Research Chair, Cameco MS Neuroscience Research Centre, Department of Anatomy, Physiology and Pharmacology, Department of Medicine, Neurology Division, College of Medicine, University of Saskatchewan, Saskatoon, SK S7K 0M7, Canada.
Publications dans "Petites ribonucléoprotéines nucléaires U2" :
The conserved SR-like protein Npl3 promotes splicing of diverse pre-mRNAs. However, the RNA sequence(s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 during the splicing reaction rema...
Small nuclear ribonucleoprotein U1 subunit 70 (SNRNP70) as one of the components of the U1 small nuclear ribonucleoprotein (snRNP) is rarely reported in cancers. This study aims to estimate the applic...
Based on the TCGA database and cohort of HCC patients, we investigated the expression patterns and prognostic value of SNRNP70 in HCC. Then, the combination of SNRNP70 and alpha-fetoprotein (AFP) in 2...
SNRNP70 was highly expressed in HCC. Its expression was increasingly high during the progression of HCC and was positively related to immune infiltration cells. Higher SNRNP70 expression indicated a p...
SNRNP70 may be a new biomarker for HCC progression and HCC diagnosis as well as prognosis. SNRNP70 combined with serum AFP may indicate the prognosis and recurrence status of HCC patients after operat...
TDP-43 is an essential RNA-binding protein strongly implicated in the pathogenesis of neurodegenerative disorders characterized by cytoplasmic aggregates and loss of nuclear TDP-43. The protein shuttl...
TDP-43 is an essential RNA-binding protein strongly implicated in the pathogenesis of neurodegenerative disorders characterized by cytoplasmic aggregates and loss of nuclear TDP-43. The protein shuttl...
HnRNPs are ubiquitously expressed RNA-binding proteins, tightly controlling posttranscriptional gene regulation. Consequently, hnRNP networks are essential for cellular homeostasis and their dysregula...
Changes in nuclear morphology, alterations to the nuclear pore complex (NPC), including loss, aggregation, and dysfunction of nucleoporins (Nups), and nucleocytoplasmic transport (NCT) abnormalities h...
We performed knockdown of hnRNP A1 in Neuro-2A cells, a neuronal cell line, to examine nuclear morphology, NPC, and NCT....
First, we examined nuclear morphology using Lamin B, wherein we observed increased nuclear envelope abnormalities in cells with hnRNP A1 knockdown as compared to control. To quantify changes in Lamin ...
Together, these data implicate hnRNP A1 as an important contributor to nuclear morphology, Nup expression and distribution, and NCT and suggest that hnRNP A1 dysfunction may lead to defects in these p...
N-acetylglucosamine kinase (NAGK) has been identified as an anchor protein that facilitates neurodevelopment with its non-canonical structural role. Similarly, small nuclear ribonucleoprotein polypept...
The resistance of tumor cells to chemotherapy drugs is a critical determinant in the recurrence and metastasis of nasopharyngeal carcinoma (NPC). Therefore, it is crucial to identify effective biotarg...
Genetic variants affecting Heterogeneous Nuclear Ribonucleoprotein U (HNRNPU) have been identified in several neurodevelopmental disorders (NDDs). HNRNPU is widely expressed in the human brain and sho...
Non-small cell lung cancer (NSCLC) is marked by complex molecular aberrations including differential expression of circular RNAs (circRNAs). hsa_circ_0002360, a circRNA, has been identified as overexp...