Lymphocytes T CD8+ : Questions médicales fréquentes
Nom anglais: CD8-Positive T-Lymphocytes
Descriptor UI:D018414
Tree Number:A15.382.490.555.567.569.220
Termes MeSH sélectionnés :
Sensitivity and Specificity
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"description": "Comment diagnostiquer une déficience en lymphocytes T CD8+ ?\nQuels tests sont utilisés pour évaluer l'activité des lymphocytes T CD8+ ?\nQuels marqueurs sont associés aux lymphocytes T CD8+ ?\nComment évaluer la réponse immunitaire des lymphocytes T CD8+ ?\nQuel rôle joue la cytométrie en flux dans le diagnostic ?",
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"description": "Quels traitements stimulent les lymphocytes T CD8+ ?\nComment les vaccins affectent-ils les lymphocytes T CD8+ ?\nLes traitements antiviraux influencent-ils les lymphocytes T CD8+ ?\nQuel rôle joue la thérapie génique pour les lymphocytes T CD8+ ?\nLes corticostéroïdes affectent-ils les lymphocytes T CD8+ ?",
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"description": "Quelles complications peuvent survenir avec une carence en lymphocytes T CD8+ ?\nLes lymphocytes T CD8+ peuvent-ils causer des maladies auto-immunes ?\nComment une réponse immunitaire inappropriée affecte-t-elle la santé ?\nQuelles sont les conséquences d'une immunothérapie sur les lymphocytes T CD8+ ?\nLes lymphocytes T CD8+ sont-ils impliqués dans le rejet de greffe ?",
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"description": "Quels facteurs augmentent le risque de carence en lymphocytes T CD8+ ?\nLe stress chronique affecte-t-il les lymphocytes T CD8+ ?\nLes infections virales influencent-elles les lymphocytes T CD8+ ?\nL'alimentation peut-elle affecter les lymphocytes T CD8+ ?\nLes traitements immunosuppresseurs impactent-ils les lymphocytes T CD8+ ?",
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"@type": "Question",
"name": "Comment diagnostiquer une déficience en lymphocytes T CD8+ ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un test sanguin pour mesurer le nombre de lymphocytes T CD8+ est effectué."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'activité des lymphocytes T CD8+ ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de prolifération cellulaire et des dosages d'interféron gamma sont utilisés."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont associés aux lymphocytes T CD8+ ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les marqueurs CD8 et CD3 sont typiquement utilisés pour identifier ces lymphocytes."
}
},
{
"@type": "Question",
"name": "Comment évaluer la réponse immunitaire des lymphocytes T CD8+ ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "On peut utiliser des tests de cytotoxicité pour mesurer leur capacité à tuer les cellules cibles."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la cytométrie en flux dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "La cytométrie en flux permet de quantifier et de caractériser les lymphocytes T CD8+ dans le sang."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une dysfonction des lymphocytes T CD8+ ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une susceptibilité accrue aux infections virales et aux cancers peut indiquer une dysfonction."
}
},
{
"@type": "Question",
"name": "Comment une carence en lymphocytes T CD8+ se manifeste-t-elle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut se manifester par des infections récurrentes et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les lymphocytes T CD8+ affectent-ils la fatigue ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une faible activité des lymphocytes T CD8+ peut contribuer à une fatigue chronique."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont associés à une activation des lymphocytes T CD8+ ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes d'inflammation et des symptômes de réponse immunitaire peuvent apparaître."
}
},
{
"@type": "Question",
"name": "Les lymphocytes T CD8+ influencent-ils les symptômes allergiques ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent moduler la réponse immunitaire, mais ne sont pas directement responsables des allergies."
}
},
{
"@type": "Question",
"name": "Comment renforcer les lymphocytes T CD8+ par l'alimentation ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants et en vitamines peut soutenir leur fonction."
}
},
{
"@type": "Question",
"name": "Le vaccin contre la grippe aide-t-il les lymphocytes T CD8+ ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il stimule la réponse des lymphocytes T CD8+ contre le virus de la grippe."
}
},
{
"@type": "Question",
"name": "Quels modes de vie favorisent la santé des lymphocytes T CD8+ ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie actif, une bonne hygiène de sommeil et la gestion du stress favorisent leur santé."
}
},
{
"@type": "Question",
"name": "Les compléments alimentaires sont-ils bénéfiques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains compléments, comme la vitamine D, peuvent soutenir la fonction des lymphocytes T CD8+."
}
},
{
"@type": "Question",
"name": "Comment éviter les infections pour protéger les lymphocytes T CD8+ ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pratiquer une bonne hygiène, se faire vacciner et éviter les contacts avec des malades aide."
}
},
{
"@type": "Question",
"name": "Quels traitements stimulent les lymphocytes T CD8+ ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les immunothérapies, comme les inhibiteurs de points de contrôle, stimulent leur activité."
}
},
{
"@type": "Question",
"name": "Comment les vaccins affectent-ils les lymphocytes T CD8+ ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccins peuvent induire une réponse des lymphocytes T CD8+ contre des pathogènes spécifiques."
}
},
{
"@type": "Question",
"name": "Les traitements antiviraux influencent-ils les lymphocytes T CD8+ ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains traitements antiviraux peuvent améliorer la fonction des lymphocytes T CD8+."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la thérapie génique pour les lymphocytes T CD8+ ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique peut être utilisée pour modifier les lymphocytes T CD8+ afin de cibler des cancers."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes affectent-ils les lymphocytes T CD8+ ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les corticostéroïdes peuvent inhiber l'activité des lymphocytes T CD8+ et réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec une carence en lymphocytes T CD8+ ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des infections graves et des cancers peuvent survenir en raison d'une carence."
}
},
{
"@type": "Question",
"name": "Les lymphocytes T CD8+ peuvent-ils causer des maladies auto-immunes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une activation excessive peut contribuer à des maladies auto-immunes par attaque des tissus."
}
},
{
"@type": "Question",
"name": "Comment une réponse immunitaire inappropriée affecte-t-elle la santé ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut entraîner des inflammations chroniques et des dommages aux tissus sains."
}
},
{
"@type": "Question",
"name": "Quelles sont les conséquences d'une immunothérapie sur les lymphocytes T CD8+ ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunothérapie peut provoquer des effets secondaires, comme des réactions auto-immunes."
}
},
{
"@type": "Question",
"name": "Les lymphocytes T CD8+ sont-ils impliqués dans le rejet de greffe ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent reconnaître les cellules étrangères et provoquer un rejet de greffe."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de carence en lymphocytes T CD8+ ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge avancé, certaines maladies chroniques et l'immunosuppression augmentent ce risque."
}
},
{
"@type": "Question",
"name": "Le stress chronique affecte-t-il les lymphocytes T CD8+ ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut diminuer leur nombre et leur efficacité."
}
},
{
"@type": "Question",
"name": "Les infections virales influencent-elles les lymphocytes T CD8+ ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections, comme le VIH, peuvent réduire leur nombre et leur fonction."
}
},
{
"@type": "Question",
"name": "L'alimentation peut-elle affecter les lymphocytes T CD8+ ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation pauvre en nutriments essentiels peut nuire à leur développement et fonction."
}
},
{
"@type": "Question",
"name": "Les traitements immunosuppresseurs impactent-ils les lymphocytes T CD8+ ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent réduire le nombre et l'activité des lymphocytes T CD8+ dans l'organisme."
}
}
]
}
]
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Most studies assessing the sensitivity and specificity of caries detection methods have been performed in vitro using the histological method as the gold standard showing inconsistent values. The aim ...
One hundred sixty children, ages 7-12 years, participated in the study. Five zones in the occlusal surfaces of 859 primary and 632 first permanent molars were examined visually using ICDAS-II, the RM ...
For all molars combined and for primary molars only, the sensitivity of ICDAS II was higher for detecting total caries (p < 0.001), caries in enamel (p < 0.001), and caries in dentin (p = 0.016), but ...
The sensitivity and specificity of ICDAS II and RM changes depending on whether the carious lesion compromises the enamel or dentin, and if the caries detection is performed in the primary molars or p...
During early phases of the SARS-CoV-2 epidemic, many research laboratories repurposed their efforts towards developing diagnostic testing that could aid public health surveillance while commercial and...
Establishing whether fasting plasma glucose (FPG), postprandial glucose (PPG), and HbA1c have the same diagnostic accuracy in NAFLD versus otherwise healthy people could inform T2DM screening recommen...
Cross-sectional analysis of the Third National Health and Nutrition Examination Survey (NHANES III) 1989-1994. T2DM was defined as PPG ≥ 200 mg/dL, FPG ≥ 126 mg/dL, or HbA1c ≥ 6.5 %. We estimated sens...
There were 3652 people with mean age 55.6 years and 49.4 % were men; 673 (18.4 %) people had NAFLD. Compared to NAFLD-free individuals, those with NAFLD had lower specificity in all pairwise compariso...
While these T2DM diagnostic criteria may capture different patients both in people with and without NAFLD, in the NAFLD population FPG appears to have the best sensitivity and there were no difference...
To determine if the sensitivity of the lateral flow test is dependent on the viral load and on the location of swabbing in the respiratory tract in children....
Phase 1: Routinely performed reverse transcriptase PCR (RT-PCR) using nose and throat (NT) swabs or endotracheal (ET) aspirates were compared with Innova lateral flow tests (LFTs) using anterior nasal...
Tertiary paediatric hospitals....
Children under the age of 18 years. Phase 1: undergoing routine testing, phase 2: known SARS-CoV-2 positive....
Phase 1: 435 paired swabs taken in 431 asymptomatic patients resulted in 8 positive RT-PCRs, 9 PCR test failures and 418 negative RT-PCRs from NT or ET swabs. The test performance of AN LFT demonstrat...
The NPV, PPV and specificity of LFTs are excellent. The sensitivity of LFTs compared with RT-PCR is good when the samples are colocated but may be reduced when the LFT swab is taken from the AN. Bucca...
NCT04629157....
Fast and reliable testing for the COVID 19 infection is the need of the hour for the development of effective and reliable tools and assays. However, it is difficult to find the performance relativity...
Single-visit testing and treatment for syphilis can reduce follow-up visits. The objectives of this study were to evaluate the performance and treatment outcomes of two dual syphilis/HIV point-of-care...
Participants aged 16 years and older were offered concurrent syphilis/HIV POCTs with fingerstick blood sampling using two extremely rapid (<5 minutes) devices (MedMira Multiplo Rapid TP/HIV test and I...
Between August 2020 and February 2022, 1526 visits were completed. Both POCTs accurately identified participants with HIV (sensitivity, 100% [24 of 24]; 95% CI, 86.2-100%; specificity, 99.6% [1319 of ...
Two extremely rapid (<5 minutes) dual syphilis/HIV POCTs showed excellent sensitivity and specificity for the diagnosis of active syphilis (RPR, ≥1:8 dilutions) and HIV and confirmed the ability to of...
Sensitivity is the proportion of people classified as diseased (i.e., no false negatives). A test with low sensitivity can be thought of as being too cautious in finding a positive result....
The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed for this systematic review and meta-analysis. The databases used were PubMed, Google Scholar, Jane, and ...
A total of 11 individual studies were included in the meta-analysis. The lowest sensitivity of MUAC with the detection of severe acute malnutrition (SAM) was 5% in Vietnam, and the highest sensitivity...
The sensitivity of MUAC is lower compared with the specificity to detect SAM, and varies from area to area....
We evaluate the diagnostic performance of dried blood microsampling combined with a high-throughput microfluidic nano-immunoassay (NIA) for the identification of anti-SARS-CoV-2 Spike IgG seropositivi...
We conducted a serological study among 192 individuals with documented prior SARS-CoV-2 infection and 44 SARS-CoV-2 negative individuals. Participants with prior SARS-CoV-2 infection had a long interv...
Using serum samples, we achieve a clinical sensitivity of 98·33% and specificity of 97·62% on NIA, affirming the high performance of NIA in participants 11 months post infection. Combining microsampli...
High sensitivity and specificity was demonstrated when testing micro-volume capillary dried blood samples using NIA, which is expected to facilitate its use in large-scale studies using home-based sam...
Magnetic resonance imaging (MRI) plays an important role in the diagnosis of leptomeningeal metastases (LM); however, some sub-centimeter lesions may be missed. Positron emission tomography/computed t...
Patients with SLM who had undergone...
A total of 16 patients with SLM were included in this study from October 2010 to April 2022. The primary tumor involved the lungs, liver, ovaries, prostate, esophagus, and unknown primary site. The me...
Trained dogs can recognize the volatile organic compounds contained in biological samples of patients with COVID-19 infection. We assessed the sensitivity and specificity of...