questionsmedicales.fr
Procédures de chirurgie opératoire
Procédures orthopédiques
Allongement osseux
Technique d'Ilizarov
Technique d'Ilizarov : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Déformations osseuses
Imagerie par résonance magnétique
Longueur osseuse
Radiographie
Chirurgie orthopédique
Douleur
Symptômes
5
Infection osseuse
Chirurgie
Distraction osseuse
Douleur
Effets secondaires
Infection
Prévention
5
Prévention des fractures
Sport
Complications
Chirurgie orthopédique
Déformations osseuses
Croissance
Traitements
5
Technique d'Ilizarov
Régénération osseuse
Fractures
Déformations osseuses
Distraction osseuse
Allongement osseux
Soins post-opératoires
Réhabilitation
Durée du traitement
Technique d'Ilizarov
Complications
5
Douleur chronique
Réhabilitation
Non-consolidation
Circulation sanguine
Facteurs de risque
5
Médicaments
Cicatrisation
Antécédents médicaux
Complications
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"@type": "Question",
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"@type": "Question",
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"@type": "Question",
"name": "Comment évaluer la longueur des os ?",
"position": 4,
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"@type": "Question",
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{
"@type": "Question",
"name": "Quels sont les symptômes d'une fracture ?",
"position": 6,
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"@type": "Question",
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"position": 7,
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{
"@type": "Question",
"name": "Quels signes indiquent une mauvaise cicatrisation ?",
"position": 8,
"acceptedAnswer": {
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"text": "Douleur persistante, mobilité limitée et déformation visible de l'os."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent survenir après la distraction osseuse ?",
"position": 9,
"acceptedAnswer": {
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"text": "Douleur, gonflement et parfois des picotements au niveau du site de distraction."
}
},
{
"@type": "Question",
"name": "Quels sont les effets secondaires possibles de la technique ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Inconfort, infection, et parfois des problèmes de croissance osseuse."
}
},
{
"@type": "Question",
"name": "Comment prévenir les fractures chez les sportifs ?",
"position": 11,
"acceptedAnswer": {
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"text": "Renforcement musculaire, échauffement adéquat et utilisation d'équipements de protection."
}
},
{
"@type": "Question",
"name": "Quelles mesures prendre pour éviter les infections post-chirurgicales ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène, suivre les instructions médicales et surveiller les signes d'infection."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications après une chirurgie osseuse ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Suivre les recommandations médicales, éviter les activités à risque et faire des contrôles réguliers."
}
},
{
"@type": "Question",
"name": "Quels conseils pour une bonne cicatrisation osseuse ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée, repos suffisant et éviter le tabac favorisent la cicatrisation."
}
},
{
"@type": "Question",
"name": "Comment prévenir les déformations osseuses chez les enfants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Surveiller la croissance, encourager l'activité physique et consulter un médecin si nécessaire."
}
},
{
"@type": "Question",
"name": "Comment fonctionne la technique d'Ilizarov ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle utilise un cadre externe pour stabiliser l'os et favoriser la régénération."
}
},
{
"@type": "Question",
"name": "Quels types de fractures sont traités par cette technique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fractures complexes, fractures non consolidées et déformations osseuses."
}
},
{
"@type": "Question",
"name": "Quel est le rôle de la distraction osseuse ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'allonger l'os progressivement en créant un nouvel os entre les segments."
}
},
{
"@type": "Question",
"name": "Quels soins post-opératoires sont nécessaires ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Surveillance des signes d'infection, gestion de la douleur et rééducation."
}
},
{
"@type": "Question",
"name": "Combien de temps dure le traitement avec la technique d'Ilizarov ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut durer de plusieurs semaines à plusieurs mois selon le cas."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de la technique d'Ilizarov ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections, douleurs chroniques, et problèmes de consolidation osseuse."
}
},
{
"@type": "Question",
"name": "Comment gérer une infection après la chirurgie ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antibiotiques et soins locaux sont nécessaires pour traiter l'infection efficacement."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une complication grave ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre élevée, douleur intense et écoulement purulent au site opératoire."
}
},
{
"@type": "Question",
"name": "Comment prévenir les douleurs chroniques après la chirurgie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une rééducation précoce et une gestion adéquate de la douleur sont essentielles."
}
},
{
"@type": "Question",
"name": "Quels sont les risques de non-consolidation osseuse ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Mauvaise circulation sanguine, infection ou mauvaise technique chirurgicale peuvent causer cela."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de fractures ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge avancé, l'ostéoporose et les activités sportives à risque augmentent ce risque."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme influence-t-il la cicatrisation osseuse ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme retarde la cicatrisation et augmente le risque d'infections post-opératoires."
}
},
{
"@type": "Question",
"name": "Quels médicaments peuvent affecter la guérison osseuse ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes et certains anti-inflammatoires peuvent retarder la guérison."
}
},
{
"@type": "Question",
"name": "Comment l'alimentation influence-t-elle la santé osseuse ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en calcium et vitamine D est essentielle pour la santé osseuse."
}
},
{
"@type": "Question",
"name": "Quels antécédents médicaux augmentent les risques de complications ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antécédents de maladies osseuses, diabète ou troubles circulatoires augmentent les risques."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 10/04/2025
Contenu vérifié selon les dernières recommandations médicales
6 publications dans cette catégorie
Affiliations :
Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, 830054, Urumqi, Xinjiang, China. ahmatjang@163.com.
6 publications dans cette catégorie
Affiliations :
Department and Clinic of Orthopaedic and Traumatologic Surgery, Wroclaw Medical University, Borowska 213, 50-556, Wroclaw, Poland.
Department of Orthopaedic and Trauma Surgery, University Hospital in Opole, Institute of Medical Sciences, University of Opole, Witosa 26, 41-405, Opole, Poland.
5 publications dans cette catégorie
Affiliations :
Department of Orthopedic Surgery, The Fourth Affiliated Hospital of Xinjiang Medical University, Traditional Chinese Medicine Hospital of Xinjiang Uyghur Autonomous Region, Ürümqi, Xinjiang, People's Republic of China. 424257832@qq.com.
Publications dans "Technique d'Ilizarov" :
4 publications dans cette catégorie
Affiliations :
Department of Orthopedics, Rehabilitation Hospital, National Research Center for Rehabilitation, Beijing, China.
Publications dans "Technique d'Ilizarov" :
4 publications dans cette catégorie
Affiliations :
Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, 830054, Urumqi, Xinjiang, China.
Publications dans "Technique d'Ilizarov" :
4 publications dans cette catégorie
Affiliations :
Department of Orthopedics and Musculoskeletal Traumatology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland. L.szelerski@gmail.com.
Publications dans "Technique d'Ilizarov" :
4 publications dans cette catégorie
Affiliations :
Department of Orthopedics and Musculoskeletal Traumatology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland.
Publications dans "Technique d'Ilizarov" :
4 publications dans cette catégorie
Affiliations :
Department of Physiotherapy in Motor Disorders and Dysfunctions, University School of Physical Education in Wroclaw, 51-612 Wroclaw, Poland.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Orthopaedic Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. hanpei_cn@163.com.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, 830054, Urumqi, Xinjiang, China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopedics and Musculoskeletal Traumatology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedic Surgery, 920th Hospital of Joint Logistics Support Force, Kunming Yunnan, 650032, P.R.China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedic Surgery, 920th Hospital of Joint Logistics Support Force, Kunming Yunnan, 650032, P.R.China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedic Surgery, 920th Hospital of Joint Logistics Support Force, Kunming Yunnan, 650032, P.R.China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedic Surgery, 920th Hospital of Joint Logistics Support Force, Kunming Yunnan, 650032, P.R.China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Orthopaedic Surgery, 920th Hospital of Joint Logistics Support Force, Kunming Yunnan, 650032, P.R.China.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Microrepair and Reconstruction, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. 8212682@qq.com.
Publications dans "Technique d'Ilizarov" :
3 publications dans cette catégorie
Affiliations :
Department of Massage and Physical Therapy, Faculty of Physiotherapy, Wroclaw University of Health and Sport Sciences, 51-612 Wrocław, Poland.
Publications dans "Technique d'Ilizarov" :
Although super-boosted lopinavir/ritonavir (LPV/r; ratio 4:4 instead of 4:1) is recommended for infants living with HIV and receiving concomitant rifampicin, in clinical practice, many different LPV/r...
This was a 2-arm pharmacokinetic substudy nested within the EMPIRICAL trial (#NCT03915366). Infants aged 1-12 months recruited into the main study were administered LPV/r according to local guidelines...
In total, 14/16 included infants had evaluable pharmacokinetic curves; 9/14 had rifampicin cotreatment (5 received double-dosed and 4 semisuperboosted LPV/r). The median (IQR) age was 6.4 months (5.4-...
Double-dosed or semisuperboosted LPV/r for infants aged 1-12 months receiving rifampicin resulted in substantial proportions of subtherapeutic LPV levels. There is an urgent need for data on alternati...
Lopinavir/ritonavir plasma concentrations are profoundly reduced when co-administered with rifampicin. Super-boosting of lopinavir/ritonavir is limited by nonavailability of single-entity ritonavir, w...
Children with HIV/tuberculosis coinfection weighing 3.0 to 19.9 kg, on rifampicin-based antituberculosis treatment were commenced or switched to 8-hourly liquid lopinavir/ritonavir 4:1 with increased ...
Of 20 children enrolled; 15, 1-7 years old, had pharmacokinetics sampling available for analysis. Lopinavir concentrations (median [range]) on 8-hourly lopinavir/ritonavir co-administered with rifampi...
Modified 8-hourly dosing of lopinavir/ritonavir failed to achieve adequate lopinavir concentrations with concurrent antituberculosis treatment. The subtherapeutic lopinavir exposures on standard dosin...
Recently, the U.S. Food and Drug Administration (FDA) approved the first oral antiviral drug to treat mild to moderate cases of coronavirus disease. The combination of nirmatrelvir with an already use...
The COVID-19 pandemic has led to a significant increase in antibiotic consumption, along with a 70% rise in antiviral drug concentrations in aquatic ecosystems. For the effective adsorption of antibio...
Effective and widely available therapies are still needed for outpatients with COVID-19. We aimed to evaluate the efficacy and safety of lopinavir/ritonavir (LPV/r) for early treatment of non-hospital...
This randomized, placebo (Plb)-controlled, double-blind, multi-site decentralized clinical trial enrolled non-hospitalized adults with confirmed SARS-CoV-2 infection and six or fewer days of acute res...
Between June 2020 and December 2021, 448 participants were randomized to receive either LPV/r (n = 216) or Plb (n = 221). The mean symptom duration before randomization was 4.3 days (SD 1.3). There we...
LPV/r did not significantly improve symptom resolution or reduce hospitalization in non-hospitalized participants with COVID-19....
ClinicalTrials.gov Identifier: NCT04372628....
Treatment of HIV and tuberculosis co-infection leads to significant mortality in pediatric patients, and treatment can be challenging due to the clinically significant drug-drug interaction (DDI) betw...
Adult and pediatric PBPK models for LPV/RTV with rifampin were developed, including CYP3A and P-glycoprotein inhibition and induction....
Data for LPV/RTV model development and evaluation were available from the pediatric AIDS Clinical Trials Group....
Dosing simulations were next performed to optimize dosing in children (2 months to 8 years of age)....
Exposure following super-boosted LPV/RTV with 10 and 15 mg/kg PO daily rifampin was simulated....
Simulated parameters were within twofold observations for LPV, RTV, and rifampin in adults and children ≥2 weeks old. The model predicted that, in healthy adults receiving 400/100 mg oral LPV/RTV twic...
Super-boosted LPV/RTV with 15 mg/kg rifampin achieves therapeutic LPV troughs in HIV/TB-infected simulated children....
Prior to dolutegravir availability, ritonavir-boosted lopinavir (LPV/r) was an alternative recommendation when first-line drugs could not be used. A high concentration of protease inhibitors was obser...
LPV and RTV trough concentrations from Thai PLWH were combined with intensive data. The data were analyzed by the nonlinear mixed-effects modeling approach. The influence of RTV concentration on LPV o...
Rifampicin (RIF) use increased LPV and RTV CL/F by 2.16-fold and 1.99-fold, respectively. The reduced dose of 300/75 and 200/150 mg twice daily provided a comparable percentage of patients achieving L...
The population pharmacokinetic model was developed by integrating the interaction between LPV and RTV. The reduced LPV/r dosage offers sufficient LPV exposure for Thai PLWH....
Study of liquid lopinavir/ritonavir (LPV/r) in young infants has been limited by concerns for its safety in neonates....
International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1106 was a phase IV, prospective, trial evaluating the safety and pharmacokinetics of antiretroviral medications administered ...
Safety and pharmacokinetics results were similar in 13/28 (46%) infants initiating LPV/r <42 weeks postmenstrual age (PMA) and in those starting ≥42 weeks PMA. LPV/r was started at a median (range) ag...
LPV/r oral solution was safely initiated in a relatively small sample size of infants ≥34 weeks PMA and >2 weeks of life. No serious drug-related safety signal was observed; however, adrenal function ...
The SARS-CoV-2 virus, which emerged in December 2019, has infected millions worldwide and caused many deaths. Due to its high mortality rate, several studies assessed the effectiveness of different dr...
Antiretroviral drug resistance is a therapeutic obstacle for people with HIV. HIV protease inhibitors darunavir and lopinavir are recommended for resistant infections. We characterized a protease muta...