Titre : Transgènes

Transgènes : Questions médicales fréquentes

Termes MeSH sélectionnés :

Manometry
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peuvent-ils être détectés dans les aliments ?\nQuelles méthodes sont utilisées pour le diagnostic des transgènes ?\nPeut-on identifier des transgènes dans des tissus humains ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Transgènes", "description": "Quels symptômes peuvent résulter de l'expression de transgènes ?\nLes transgènes provoquent-ils des effets indésirables ?\nY a-t-il des symptômes associés aux aliments transgéniques ?\nLes transgènes peuvent-ils affecter la santé humaine ?\nQuels symptômes sont liés aux thérapies géniques ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Transgènes", "description": "Comment prévenir les risques liés aux transgènes ?\nPeut-on éviter les aliments transgéniques ?\nQuelles mesures de sécurité sont prises pour les transgènes ?\nComment sensibiliser sur les transgènes ?\nLes organismes de réglementation surveillent-ils les transgènes ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Transgènes", "description": "Comment les transgènes sont-ils utilisés en médecine ?\nLes transgènes peuvent-ils traiter des maladies ?\nQuels traitements utilisent des transgènes ?\nLes transgènes sont-ils utilisés en oncologie ?\nQuels sont les risques des traitements par transgènes ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Transgènes", "description": "Quelles complications peuvent survenir avec les transgènes ?\nLes transgènes peuvent-ils causer des maladies ?\nY a-t-il des complications environnementales liées aux transgènes ?\nComment les transgènes affectent-ils la santé publique ?\nLes transgènes peuvent-ils affecter la reproduction ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Transgènes", "description": "Quels facteurs augmentent les risques liés aux transgènes ?\nLes allergies sont-elles un facteur de risque pour les transgènes ?\nL'environnement joue-t-il un rôle dans les risques des transgènes ?\nLes antécédents médicaux influencent-ils les risques liés aux transgènes ?\nL'âge est-il un facteur de risque pour les effets des transgènes ?", "url": "https://questionsmedicales.fr/mesh/D019076?mesh_terms=Manometry&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment détecte-t-on des transgènes dans un organisme ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "On utilise des techniques comme la PCR et le séquençage pour identifier les transgènes." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour analyser les transgènes ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent l'analyse de l'ADN par électrophorèse et la hybridation." } }, { "@type": "Question", "name": "Les transgènes peuvent-ils être détectés dans les aliments ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des tests spécifiques peuvent identifier la présence de transgènes dans les aliments." } }, { "@type": "Question", "name": "Quelles méthodes sont utilisées pour le diagnostic des transgènes ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les méthodes incluent la PCR quantitative et les tests de Southern blot." } }, { "@type": "Question", "name": "Peut-on identifier des transgènes dans des tissus humains ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des techniques comme la PCR peuvent détecter des transgènes dans des échantillons de tissus." } }, { "@type": "Question", "name": "Quels symptômes peuvent résulter de l'expression de transgènes ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes varient selon le transgène, mais peuvent inclure des réactions immunitaires." } }, { "@type": "Question", "name": "Les transgènes provoquent-ils des effets indésirables ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des effets indésirables peuvent survenir, comme des allergies ou des toxicités." } }, { "@type": "Question", "name": "Y a-t-il des symptômes associés aux aliments transgéniques ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Certaines personnes peuvent éprouver des symptômes allergiques après consommation." } }, { "@type": "Question", "name": "Les transgènes peuvent-ils affecter la santé humaine ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des études suggèrent que certains transgènes peuvent avoir des impacts sur la santé." } }, { "@type": "Question", "name": "Quels symptômes sont liés aux thérapies géniques ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les thérapies géniques peuvent entraîner des réactions comme de la fièvre ou des douleurs." } }, { "@type": "Question", "name": "Comment prévenir les risques liés aux transgènes ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La réglementation stricte et les tests de sécurité sont essentiels pour prévenir les risques." } }, { "@type": "Question", "name": "Peut-on éviter les aliments transgéniques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, en choisissant des produits bio ou en lisant les étiquettes des aliments." } }, { "@type": "Question", "name": "Quelles mesures de sécurité sont prises pour les transgènes ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Des études de sécurité et des évaluations environnementales sont réalisées avant leur utilisation." } }, { "@type": "Question", "name": "Comment sensibiliser sur les transgènes ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Des campagnes d'information et des programmes éducatifs peuvent sensibiliser le public." } }, { "@type": "Question", "name": "Les organismes de réglementation surveillent-ils les transgènes ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des organismes comme l'EFSA surveillent l'utilisation et la sécurité des transgènes." } }, { "@type": "Question", "name": "Comment les transgènes sont-ils utilisés en médecine ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Ils sont utilisés pour développer des thérapies géniques pour traiter des maladies génétiques." } }, { "@type": "Question", "name": "Les transgènes peuvent-ils traiter des maladies ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les transgènes sont utilisés pour traiter des maladies comme la fibrose kystique." } }, { "@type": "Question", "name": "Quels traitements utilisent des transgènes ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements comme la thérapie génique et les vaccins génétiquement modifiés en font partie." } }, { "@type": "Question", "name": "Les transgènes sont-ils utilisés en oncologie ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils sont utilisés pour développer des traitements ciblés contre certains cancers." } }, { "@type": "Question", "name": "Quels sont les risques des traitements par transgènes ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les risques incluent des réactions immunitaires et des effets secondaires imprévus." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec les transgènes ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des réactions allergiques et des effets à long terme non prévus." } }, { "@type": "Question", "name": "Les transgènes peuvent-ils causer des maladies ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Il existe des préoccupations sur le potentiel des transgènes à induire des maladies." } }, { "@type": "Question", "name": "Y a-t-il des complications environnementales liées aux transgènes ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des impacts sur la biodiversité et des effets sur les écosystèmes sont possibles." } }, { "@type": "Question", "name": "Comment les transgènes affectent-ils la santé publique ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent poser des risques pour la santé publique, nécessitant une surveillance continue." } }, { "@type": "Question", "name": "Les transgènes peuvent-ils affecter la reproduction ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Des études suggèrent que certains transgènes pourraient avoir des effets sur la reproduction." } }, { "@type": "Question", "name": "Quels facteurs augmentent les risques liés aux transgènes ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "L'exposition à des transgènes non réglementés et la consommation d'aliments non testés augmentent les risques." } }, { "@type": "Question", "name": "Les allergies sont-elles un facteur de risque pour les transgènes ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les personnes allergiques peuvent avoir des réactions plus sévères aux aliments transgéniques." } }, { "@type": "Question", "name": "L'environnement joue-t-il un rôle dans les risques des transgènes ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les conditions environnementales peuvent influencer l'impact des transgènes sur la santé." } }, { "@type": "Question", "name": "Les antécédents médicaux influencent-ils les risques liés aux transgènes ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents d'allergies ou de maladies auto-immunes peuvent augmenter les risques." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque pour les effets des transgènes ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les jeunes enfants et les personnes âgées peuvent être plus sensibles aux effets des transgènes." } } ] } ] }

Sources (342 au total)

Comparison of electromyography, sound, bioimpedance, and high-resolution manometry for differentiating swallowing and vocalization events.

Non-invasive surface recording devices used for detecting swallowing events include electromyography (EMG), sound, and bioimpedance. However, to our knowledge there are no comparative studies in which... Six participants randomly performed saliva swallow or vocalization of "ah" 62 times. Pharyngeal pressure data were obtained using an HRM catheter. EMG, sound, and bioimpedance data were recorded using... Classification accuracy was significantly different between the four measurement methods (P < 0.001). The highest classification accuracy was for HRM topography (>99%), followed by sound and bioimpeda... HRM, EMG, sound, and bioimpedance have fairly reliable discrimination capabilities for swallowing and non-swallowing events. User experience with EMG may increase identification and interrater reliabi...

Association of delivery mode and number of pregnancies with anorectal manometry data in patients with postpartum constipation.

To explore the association of delivery mode and the number of pregnancies with anorectal manometry data in patients with postpartum constipation.... This retrospective study included women with postpartum constipation treated at the pelvic floor rehabilitation department of Huzhou Maternity & Child Health Care Hospital between January 2018 and Dec... Among 127 patients included, 55 (43.3%) had one pregnancy, 72 (56.7%) had two pregnancies, 96 (75.6%) delivered spontaneously, 25 (16.7%) underwent Cesarean section, and six (4.7%) needed a Cesarean s... The patients with a spontaneous delivery had a lower change in maximal contracting sphincter pressure compared with those with a Cesarean section, suggesting that patients with Cesarean may retain a b...

The colonic motility and classification of patients with slow transit constipation by high-resolution colonic manometry.

This study aimed to evaluate the colonic motility of slow transit constipation (STC) patients using high-resolution colonic manometry (HRCM) and classify the patients' subtypes to instruct treatment b... This study enrolled one hundred and twenty-six STC patients and 35 volunteers (healthy controls, HCs). Ambulatory HRCM was performed in all participants by placing a 36-sensor water-perfused probe up ... The occurrence rate and times of high amplitude propagated contraction (HAPC) in STC patients were lower than HCs. As for the HAPC contraction characteristics, the mean velocity was similar, contracti... HRCM serves as a valuable tool in characterizing, classifying the pathophysiology, and guiding clinical management for STC....

Evaluating the impact of position, volume, and consistency on high-resolution esophageal manometry outcomes.

The Chicago classification primarily utilizes ten 5 mL liquid swallows in a supine position as the standard high-resolution esophageal manometry (HRM) protocol. HRM can be performed with varying volum... HRM was performed in healthy volunteers (HV) with the following protocol of swallows: liquids 10 × 5 mL, 5 × 10 mL, and 3 × 10 mL multiple rapid swallows; applesauce 5 × 5 mL and 5 × 10 mL; and bread ... Thirty-seven HVs, median age 27 years, 64% female completed this study. Median distal contractile integral (DCI) and integrated relaxation pressure 4 s (IRP4) of 5 mL liquid swallows significantly dif... The volume and consistency of a swallow and the position it is performed in, significantly alter HRM metrics. Interpretation of HRM studies should incorporate different normative values which are spec...

Ethnic Differences in Clinical Presentations and Esophageal High-Resolution Manometry Findings in Patients with Achalasia.

Ethnic differences in achalasia presentations have scarcely been described. The association between achalasia and immunologic HLA haplotypes suggests that there may be a genetic predisposition. We aim... A retrospective study was performed at two medical centers. High-resolution manometry (HRM) reports were reviewed for newly-diagnosed achalasia patients. Demographic data, clinical presentations, endo... Overall, 94 achalasia patients were included (53.2% male; mean age 54.5 ± 18.0). 43 patients were IA (45.7%). Body mass index (BMI) was similar in both groups. Compared to IJ, the IA patients had more... Ethnicity appears to affect achalasia clinical presentation and HRM findings. IA achalasia patients are diagnosed at a younger age, present with more severe esophageal symptoms, and have a higher IRP ...

The role of anal manometry in the follow-up of women with obstetric anal sphincter injuries (OASI).

Mode of birth (MOB) following OASI is determined by choice, symptoms and anorectal study results in asymptomatic women. Endoanal ultrasound (EAUS) is the gold-standard imaging modality. EAUS use in MO... A retrospective observational study was conducted from 2007 to 2020. Women underwent symptom assessment using validated ePAQ and St Mark's incontinence score (SMIS). Anorectal studies using EAUS and A... A total of 1348 women were included over 13 years. Among these, 454 women were symptomatic, 894 were asymptomatic; 274 (31%) asymptomatic women had isolated abnormal AM results, 313 (35%) had two abno... AM identifies more women with sphincter function impairment than EAUS alone. Without AM, almost one third of asymptomatic women would not have been identified and could have been inadequately counsell...

Investigating the diagnostic utility of high-resolution oesophageal manometry in patients with refractory respiratory symptoms.

The interaction between the respiratory and gastrointestinal systems, and the role of the latter in the development of respiratory pathology, has been examined with a focus on gastro-oesophageal reflu... In this study, we examined patterns in oesophageal motility using high-resolution oesophageal manometry (HROM) in patients with refractory respiratory symptoms.... Data were collected retrospectively for all patients that were investigated using HROM at a single centre for refractory respiratory symptoms between January 1st, 2011-December 1st, 2021. Patients wer... 441 patients were investigated with HROM (64% female, mean age = 56.5 [SD = 13.9]). The commonest diagnoses of these patients were Chronic Cough (77%, n = 339), Asthma (10%, n = 44), and Interstitial ... Two-thirds of patients with refractory respiratory symptoms were found to have oesophageal dysmotility on HROM. These findings suggest motility disorders of the oesophagus may contribute to the develo...

Comparison of Anorectal Manometry, Rectal Balloon Expulsion Test, and Defecography for Diagnosing Defecatory Disorders.

The utility of high-resolution anorectal manometry (HR-ARM) for diagnosing defecatory disorders (DDs) is unclear because healthy people may have features of dyssynergia. We aimed to identify objective... Constipated patients were assessed with HR-ARM and rectal balloon expulsion time (BET), and a subset underwent defecography. Normal values were established by assessing 184 sex-matched healthy individ... A total of 474 constipated individuals (420 women) underwent HR-ARM and BET, and 158 underwent defecography. BET was prolonged, suggesting a DD, for 152 patients (32%). Rectal evacuation was lower for... HR-ARM, BET, and defecography findings were concordant for constipated patients, and reduced rectoanal gradient was the best HR-ARM predictor of prolonged BET or reduced rectal evacuation. Prolonged B...

Should anorectal manometry be routine before stoma reversal in patients after an intersphincteric resection?

Anorectal manometry (ARM) is sometimes performed before ostomy reversal in patients with an intersphincteric resection (ISR) to predict bowel function. However, no clinical predictive data exist regar... The single-centre, retrospective data of ISR patients who had an ARM prior to ostomy reversal, and bowel functional assessment with the low anterior resection syndrome (LARS) and Wexner incontinence s... Eighty-nine patients were included. The median basal and squeeze pressures were 41 and 100 mmHg, respectively. Any LARS (score ≥20) and major incontinence (score ≥11) was observed in 51.7% and 16.9%, ... Anorectal manometry (ARM) before ostomy reversal to predict bowel function at 6 months or beyond was not helpful in patients with an ISR and diverting stoma. No manometric parameter correlated with th...

Impact of peroral endoscopic myotomy on high-resolution manometry findings and their association with the procedure's outcomes.

Peroral endoscopic myotomy (POEM) is conducted for patients with esophageal motility disorders based on high-resolution manometry (HRM) findings. However, the impact of POEM on HRM findings and the as... In a multicenter, observational, cohort study, patients with achalasia treated by POEM received follow-up HRM. Associations between patient characteristics, POEM procedures, and post-POEM HRM findings... Of 2171 patients, 151 (7.0%) showed residual high post-POEM IRP (≥26 mm Hg; Starlet [Starmedical Ltd, Tokyo, Japan]). In a multivariate analysis, high pre-POEM IRPs (odds ratio [OR], 24.3) and gastric... Extended gastric myotomy decreased IRP values, whereas peristalsis recovery depended on the characteristics of achalasia. A residual high post-POEM IRP does not necessarily mean clinical failure. Rout...