Comment diagnostiquer une dysrégulation des chimiokines CXC ?

Des tests sanguins et des analyses de cytokines peuvent aider à évaluer les niveaux de chimiokines.

Quels tests sont utilisés pour mesurer les chimiokines CXC ?

Les dosages ELISA et les tests multiplex sont couramment utilisés pour mesurer les chimiokines.

Les chimiokines CXC sont-elles liées à des maladies spécifiques ?

Oui, elles sont souvent associées à des maladies inflammatoires et auto-immunes.

Peut-on détecter les chimiokines CXC dans les biopsies ?

Oui, les chimiokines peuvent être détectées dans les tissus par immunohistochimie.

Les niveaux de chimiokines CXC varient-ils selon l'âge ?

Oui, les niveaux de chimiokines peuvent varier avec l'âge et l'état de santé général.

Quels symptômes sont associés à une surproduction de chimiokines CXC ?

Les symptômes incluent inflammation, douleur, fatigue et troubles immunitaires.

Les chimiokines CXC peuvent-elles causer des symptômes respiratoires ?

Oui, elles sont impliquées dans des maladies respiratoires comme l'asthme et la BPCO.

Comment les chimiokines CXC affectent-elles le système nerveux ?

Elles peuvent contribuer à des troubles neurologiques en modulant l'inflammation cérébrale.

Les chimiokines CXC sont-elles liées à des symptômes cutanés ?

Oui, elles peuvent être impliquées dans des maladies cutanées inflammatoires comme le psoriasis.

Peut-on observer des symptômes digestifs liés aux chimiokines CXC ?

Oui, elles peuvent jouer un rôle dans des maladies inflammatoires de l'intestin.

Peut-on prévenir les maladies liées aux chimiokines CXC ?

Une bonne hygiène de vie et la gestion du stress peuvent aider à prévenir certaines maladies.

L'alimentation influence-t-elle les chimiokines CXC ?

Oui, une alimentation riche en antioxydants peut réduire l'inflammation et les chimiokines.

L'exercice physique affecte-t-il les niveaux de chimiokines CXC ?

Oui, l'exercice régulier peut moduler les niveaux de chimiokines et améliorer la santé immunitaire.

Le tabagisme influence-t-il les chimiokines CXC ?

Oui, le tabagisme augmente les niveaux de chimiokines et contribue à l'inflammation.

Le stress chronique affecte-t-il les chimiokines CXC ?

Oui, le stress chronique peut augmenter l'expression des chimiokines et aggraver l'inflammation.

Quels traitements ciblent les chimiokines CXC ?

Des thérapies biologiques et des inhibiteurs de chimiokines sont en développement.

Les corticostéroïdes affectent-ils les chimiokines CXC ?

Oui, les corticostéroïdes peuvent réduire l'expression des chimiokines CXC dans l'inflammation.

Comment les inhibiteurs de chimiokines CXC fonctionnent-ils ?

Ils bloquent les récepteurs des chimiokines, réduisant ainsi l'inflammation et la migration cellulaire.

Les traitements anti-inflammatoires influencent-ils les chimiokines CXC ?

Oui, ils peuvent moduler les niveaux de chimiokines et améliorer les symptômes inflammatoires.

Y a-t-il des essais cliniques sur les chimiokines CXC ?

Oui, plusieurs essais cliniques évaluent des traitements ciblant les chimiokines CXC.

Quelles complications peuvent survenir avec des niveaux élevés de chimiokines CXC ?

Des complications incluent des maladies auto-immunes, des infections chroniques et des cancers.

Les chimiokines CXC sont-elles impliquées dans le cancer ?

Oui, elles peuvent favoriser la progression tumorale et la métastase dans certains cancers.

Comment les chimiokines CXC affectent-elles la cicatrisation des plaies ?

Une surproduction peut retarder la cicatrisation en exacerbant l'inflammation.

Les maladies cardiovasculaires sont-elles liées aux chimiokines CXC ?

Oui, des niveaux élevés de chimiokines sont associés à un risque accru de maladies cardiovasculaires.

Les chimiokines CXC peuvent-elles causer des troubles neurologiques ?

Oui, elles sont impliquées dans des troubles comme la sclérose en plaques et l'Alzheimer.

Quels facteurs de risque augmentent les niveaux de chimiokines CXC ?

L'obésité, le tabagisme et le stress chronique sont des facteurs de risque connus.

Les infections peuvent-elles influencer les chimiokines CXC ?

Oui, les infections aiguës et chroniques peuvent augmenter l'expression des chimiokines.

L'exposition à des polluants affecte-t-elle les chimiokines CXC ?

Oui, l'exposition à des polluants environnementaux peut augmenter les niveaux de chimiokines.

Le vieillissement influence-t-il les chimiokines CXC ?

Oui, le vieillissement peut entraîner une augmentation des niveaux de chimiokines et de l'inflammation.

Les maladies métaboliques sont-elles liées aux chimiokines CXC ?

Oui, des maladies comme le diabète peuvent augmenter les niveaux de chimiokines et l'inflammation.

Chimiokines CXC - Informations médicales vérifiées

Effectiveness of gluteal control training in chronic low back pain patients with functional leg length inequality.

18 Oct 2024

DOI: 10.1038/s41598-024-74348-x PMID: 39424858

Chronic low back pain (LBP) is a common musculoskeletal disorder and is often accompanied by functional leg length inequality (FLLI). However, little was known about the effects of gluteal muscle cont...

Humans Low Back Pain Female Male Middle Aged +10 autres

Asymmetric Flexion Contracture is Associated With Leg Length Inequality in Patients With Knee Osteoarthritis: Data From the Osteoarthritis Initiative.

Dec 2023

DOI: 10.1016/j.apmr.2023.04.021 PMID: 37209935

To evaluate whether knee flexion contracture (FC) was associated with leg length inequality (LLI) and/or morbidity in knee osteoarthritis (OA).... We accessed 2 databases: (1) the Osteoarthritis Initiative (OAI) cohort, including participants with, or at-risk of OA, and (2) the Ottawa Knee Osteoarthritis cross-sectional database (OKOA), includin... Tertiary care academic rheumatology and orthopedic clinics.... Patients with or at-risk of primary OA. We included 881 OAI and 72 OKOA participants (N=953).... Not applicable.... The primary outcome tested the association between the difference in knee extensions of the OA and contralateral knees (the knee extension difference, or KExD) and LLI. This was evaluated using bivari... OAI participants had less severe knee OA [Kellgren and Lawrence (KL) score 1.9±1.3] vs OKOA (KL score 3.4±0.6). The KExD correlated with LLI for both databases (OAI: R=0.167; P≤.001; OKOA: R=0.339; P=... OA-related loss of knee extension was associated with LLI for those with moderate-severe OA. Because LLI correlates with worse knee OA symptoms, discovering an FC should cue clinicians to evaluate for...

Humans Osteoarthritis, Knee Leg Leg Length Inequality Knee Joint +2 autres

Induced leg length inequality affects pelvis orientation during upright standing immediately following a sit-to-stand transfer: a pre-post measurement study.

17 Mar 2023

DOI: 10.1186/s12891-023-06302-3 PMID: 36932408

Leg length inequality (LLI) greater than 20 mm has been associated with low back pain (LBP) and its correction is clinically recommended. Much less is known about the biomechanical effects that LLI be... Twenty-two adult participants (8 female) aged between 18 and 30 years without LBP were enrolled in the study and completed a series of sit-to-stand trials with no heel-lift (0 mm baseline) and heel-li... Left frontal plane rotation of the pelvis increased (p = 0.001), that is, the left side of the pelvis was lower than the right side of the pelvis, and anterior tilt of the pelvis decreased (p = 0.020)... These findings suggest that correcting leg length inequality below the recommended threshold of 20 mm may influence pelvic orientation. Future work can investigate the effects of the altered orientati...

Adult Humans Female Adolescent Young Adult +7 autres

[Options and limits of leg length correction in paediatric orthopaedics].

Sep 2023

DOI: 10.1007/s00132-023-04420-3 PMID: 37561147

For paediatric orthopaedic surgeons treating leg length discrepancy, knowledge of the available procedures and their options and limits is just as important as mastery of the very different surgical m...

Adolescent Humans Child Orthopedics Leg +3 autres

Perioperative management of leg-length discrepancy in total hip arthroplasty: a review.

Aug 2023

DOI: 10.1007/s00402-022-04759-w PMID: 36629905

Leg-length discrepancy (LLD) presents a significant management challenge to orthopedic surgeons and remains a leading cause of patient dissatisfaction and litigation after total hip arthroplasty (THA)...

Humans Arthroplasty, Replacement, Hip Leg Leg Length Inequality

Relationship between perceived and structural leg length discrepancies of patients with hip osteoarthritis dysplasia.

06 2023

DOI: 10.1016/j.otsr.2023.103570 PMID: 36750154

Only few studies have been conducted on leg length discrepancy (LLD) in patients with hip osteoarthritis (OA). This study aimed to examine the relationship between perceived LLD (pLLD) and structural ... We hypothesized that older adults are less likely to perceive LLD than younger adults.... We recruited 125 patients (102 women and 23 men) with hip OA associated with developmental dysplasia of the hip defined as grade 3 or higher according to the Tönnis classification and excluding contra... The absolute difference between pLLD and sLLD was modestly positively correlated with age (R=0.206; p<0.05) indicating older patients were less prone to perceive LLD. A strong positive correlation was... Older patients had less pLLD. Preoperative pLLD was strongly correlated with sLLD but not with patient satisfaction. These results may be useful for conservative treatment of OA, preoperative planning... IV; case control study....

Male Humans Female Aged Middle Aged +8 autres

Magnitude of Change in Leg Length and Clinical Impact Following Medial Unicompartmental Knee Arthroplasty.

Jan 2024

DOI: 10.1016/j.arth.2023.07.013 PMID: 37479193

Change in leg length and leg-length discrepancy (LLD) are common concerns among patients undergoing medial unicompartmental knee arthroplasty (UKA). This study aimed to quantify the magnitude of leg-l... Leg length and mechanical hip-knee-ankle angle (mHKA) were retrospectively measured in 332 patients following unilateral robotic-arm assisted medial UKA for medial compartment osteoarthritis, using ca... Following medial UKA, median leg-length change was 2.0 mm (interquartile range, -1.0 to 5.0 mm; P < .001) with a mean correction in mHKA of 4.4° ± 2.7 (P < .001). A total of 158 patients (48%) had a l... Following medial UKA, the majority of patients had a moderate increase in leg length, the magnitude of which was positively correlated to the correction in mechanical alignment. Postoperative substant...

Humans Arthroplasty, Replacement, Knee Osteoarthritis, Knee Retrospective Studies Leg +5 autres

Clinically Detected Leg Length Discrepancy in Patients With Idiopathic Clubfoot Deformity: Prevalence and Outcomes.

01 Aug 2022

DOI: 10.1097/BPO.0000000000002178 PMID: 35543605

This study evaluates the prevalence and outcomes of patients with idiopathic clubfoot and clinically detected limb length discrepancy (LLD).... This is a retrospective cohort study of idiopathic clubfoot patients in a Research Ethics Board-approved clubfoot registry. Patients with LLD ≥0.5 cm (LLD+) were compared with those with no or <0.5 cm... Of the 300 patients included, 27 (9.0%) had an LLD, of whom 23 patients had a unilateral clubfoot deformity. The prevalence of LLD was 15.3% and 2.67% in unilateral and bilateral clubfoot patients, re... LLD was present in 9% of idiopathic clubfoot patients, and most were <2 cm. There is a significantly higher risk of relapse in patients with unilateral clubfoot and LLD. The risk of surgery overall wa... Level III....

Casts, Surgical Clubfoot Humans Infant Leg +6 autres

Measurement Techniques for Leg Length Discrepancy in Total Hip Arthroplasty: A Systematic Review of Reliability and Validity.

12 2022

DOI: 10.1016/j.arth.2022.05.029 PMID: 35605764

Total hip arthroplasty (THA) carries a substantial litigative burden. THA may introduce leg length discrepancy (LLD), necessitating a valid and reliable technique for LLD measurement. This study inves... Embase and MEDLINE databases were searched following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for articles assessing either the validity or reliability of LLD meas... Forty-two articles with 2059 participants were included. Thirty-three investigated reliability and 25 validity. Reliability displayed high heterogeneity. Poor to excellent intra-rater reliability was ... The reported intra- and inter-rater reliability for most measurement techniques vary widely. The tape measure method is a valid clinical measurement of LLD. Imaging techniques have been appropriately ...

Humans Arthroplasty, Replacement, Hip Reproducibility of Results Leg Leg Length Inequality +1 autres

Leg length discrepancies (LLD): An etiology to be considered in its proper measure. A critical and historical review.

Apr 2024

DOI: 10.1016/j.jbmt.2024.01.036 PMID: 38763584

Studies of leg-length discrepancies (LLD) have been the subject of debate for almost 200 years. A large number of studies have emerged, most frequently using assessment criteria based on painful sympt... While many authors argue for a threshold of 10-20 mm to establish a link between pain and LLD, most publications based on radiography show lesion stigmata on lumbar, hip and knee joints as early as 6 ... Some studies argue forcefully that leg-length correction below 20 mm is of no benefit. The authors of the present article, on the other hand, evoke the notion of lesion risks in the absence of correct... The authors argue for the need to define in the future a lesion significance score that would not be correlated to painful symptomatology, but rather to the presence of co-morbidities such as age, ana...

Humans Leg Length Inequality

Chimiokines CXC : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Chimiokine CXCL1

Chimiokine CXCL16

Chimiokine CXCL5

Chimiokine CXCL6

Chimiokine CXCL9

Chimiokine CXCL10

Chimiokine CXCL11

Chimiokine CXCL12

Chimiokine CXCL13

Facteur-4 plaquettaire

Auteurs principaux

Sources (10000 au total)