Comment diagnostiquer une dysrégulation des chimiokines CXC ?

Des tests sanguins et des analyses de cytokines peuvent aider à évaluer les niveaux de chimiokines.

Quels tests sont utilisés pour mesurer les chimiokines CXC ?

Les dosages ELISA et les tests multiplex sont couramment utilisés pour mesurer les chimiokines.

Les chimiokines CXC sont-elles liées à des maladies spécifiques ?

Oui, elles sont souvent associées à des maladies inflammatoires et auto-immunes.

Peut-on détecter les chimiokines CXC dans les biopsies ?

Oui, les chimiokines peuvent être détectées dans les tissus par immunohistochimie.

Les niveaux de chimiokines CXC varient-ils selon l'âge ?

Oui, les niveaux de chimiokines peuvent varier avec l'âge et l'état de santé général.

Quels symptômes sont associés à une surproduction de chimiokines CXC ?

Les symptômes incluent inflammation, douleur, fatigue et troubles immunitaires.

Les chimiokines CXC peuvent-elles causer des symptômes respiratoires ?

Oui, elles sont impliquées dans des maladies respiratoires comme l'asthme et la BPCO.

Comment les chimiokines CXC affectent-elles le système nerveux ?

Elles peuvent contribuer à des troubles neurologiques en modulant l'inflammation cérébrale.

Les chimiokines CXC sont-elles liées à des symptômes cutanés ?

Oui, elles peuvent être impliquées dans des maladies cutanées inflammatoires comme le psoriasis.

Peut-on observer des symptômes digestifs liés aux chimiokines CXC ?

Oui, elles peuvent jouer un rôle dans des maladies inflammatoires de l'intestin.

Peut-on prévenir les maladies liées aux chimiokines CXC ?

Une bonne hygiène de vie et la gestion du stress peuvent aider à prévenir certaines maladies.

L'alimentation influence-t-elle les chimiokines CXC ?

Oui, une alimentation riche en antioxydants peut réduire l'inflammation et les chimiokines.

L'exercice physique affecte-t-il les niveaux de chimiokines CXC ?

Oui, l'exercice régulier peut moduler les niveaux de chimiokines et améliorer la santé immunitaire.

Le tabagisme influence-t-il les chimiokines CXC ?

Oui, le tabagisme augmente les niveaux de chimiokines et contribue à l'inflammation.

Le stress chronique affecte-t-il les chimiokines CXC ?

Oui, le stress chronique peut augmenter l'expression des chimiokines et aggraver l'inflammation.

Quels traitements ciblent les chimiokines CXC ?

Des thérapies biologiques et des inhibiteurs de chimiokines sont en développement.

Les corticostéroïdes affectent-ils les chimiokines CXC ?

Oui, les corticostéroïdes peuvent réduire l'expression des chimiokines CXC dans l'inflammation.

Comment les inhibiteurs de chimiokines CXC fonctionnent-ils ?

Ils bloquent les récepteurs des chimiokines, réduisant ainsi l'inflammation et la migration cellulaire.

Les traitements anti-inflammatoires influencent-ils les chimiokines CXC ?

Oui, ils peuvent moduler les niveaux de chimiokines et améliorer les symptômes inflammatoires.

Y a-t-il des essais cliniques sur les chimiokines CXC ?

Oui, plusieurs essais cliniques évaluent des traitements ciblant les chimiokines CXC.

Quelles complications peuvent survenir avec des niveaux élevés de chimiokines CXC ?

Des complications incluent des maladies auto-immunes, des infections chroniques et des cancers.

Les chimiokines CXC sont-elles impliquées dans le cancer ?

Oui, elles peuvent favoriser la progression tumorale et la métastase dans certains cancers.

Comment les chimiokines CXC affectent-elles la cicatrisation des plaies ?

Une surproduction peut retarder la cicatrisation en exacerbant l'inflammation.

Les maladies cardiovasculaires sont-elles liées aux chimiokines CXC ?

Oui, des niveaux élevés de chimiokines sont associés à un risque accru de maladies cardiovasculaires.

Les chimiokines CXC peuvent-elles causer des troubles neurologiques ?

Oui, elles sont impliquées dans des troubles comme la sclérose en plaques et l'Alzheimer.

Quels facteurs de risque augmentent les niveaux de chimiokines CXC ?

L'obésité, le tabagisme et le stress chronique sont des facteurs de risque connus.

Les infections peuvent-elles influencer les chimiokines CXC ?

Oui, les infections aiguës et chroniques peuvent augmenter l'expression des chimiokines.

L'exposition à des polluants affecte-t-elle les chimiokines CXC ?

Oui, l'exposition à des polluants environnementaux peut augmenter les niveaux de chimiokines.

Le vieillissement influence-t-il les chimiokines CXC ?

Oui, le vieillissement peut entraîner une augmentation des niveaux de chimiokines et de l'inflammation.

Les maladies métaboliques sont-elles liées aux chimiokines CXC ?

Oui, des maladies comme le diabète peuvent augmenter les niveaux de chimiokines et l'inflammation.

Chimiokines CXC - Informations médicales vérifiées

Speech intelligibility changes the temporal evolution of neural speech tracking.

03 2023

DOI: 10.1016/j.neuroimage.2023.119894 PMID: 36693596

Listening to speech with poor signal quality is challenging. Neural speech tracking of degraded speech has been used to advance the understanding of how brain processes and speech intelligibility are ...

Humans Speech Intelligibility Speech Perception Brain Auditory Perception +2 autres

A Transparent Mask and Clear Speech Benefit Speech Intelligibility in Individuals With Hearing Loss.

09 11 2023

DOI: 10.1044/2023_JSLHR-22-00636 PMID: 37788660

The purpose of the study is to investigate the impacts of a surgical mask and a transparent mask on audio-only and audiovisual speech intelligibility in noise (i.e., 0 dB signal-to-noise ratio) in ind... Thirty-one individuals with hearing loss (from 22 to 74 years old) completed keyword identification tasks to measure face-masked speech intelligibility in noise. A mixed-effects logistic regression mo... In the audio-only mode, the GHL group showed reduced speech intelligibility regardless of other factors, whereas the MHL group showed decreased speech intelligibility for the transparent mask more tha... The findings indicate that, when using face masks, either a transparent mask or a surgical mask negatively affects speech understanding in noise for individuals with hearing loss. Using a transparent ...

Humans Young Adult Adult Middle Aged Aged +6 autres

Vowel Acoustics as Predictors of Speech Intelligibility in Dysarthria.

17 08 2023

DOI: 10.1044/2022_JSLHR-22-00287 PMID: 36795536

This study sought to determine if alternative vowel space area (VSA) measures (i.e., novel trajectory-based measures: vowel space hull area and vowel space density) predicted speech intelligibility to... The Grandfather Passage was read aloud by 40 speakers with dysarthria of varying etiologies, including Parkinson's disease (... Traditional VSA was the sole significant predictor of speech intelligibility for both the OTs (... The findings suggest that traditional token-based vowel measures better predict intelligibility than trajectory-based measures. Additionally, the findings suggest that VAS methods are comparable to OT...

Humans Speech Intelligibility Dysarthria Speech Acoustics Phonetics +2 autres

ASR-based speech intelligibility prediction: A review.

12 2022

DOI: 10.1016/j.heares.2022.108606 PMID: 36154977

Various types of methods and approaches are available to predict the intelligibility of speech signals, but many of these still suffer from two major problems: first, their required prior knowledge, w...

Speech Intelligibility Cognition Generalization, Psychological Machine Learning Speech Perception

Lexical Predictors of Intelligibility in Young Children's Speech.

17 08 2023

DOI: 10.1044/2022_JSLHR-22-00294 PMID: 36626389

Speech perception is a probabilistic process, integrating bottom-up and top-down sources of information, and the frequency and phonological neighborhood of a word can predict how well it is perceived.... We measured the intelligibility of 165 children between 30 and 47 months in age on 38 different single words. We performed an item response analysis using generalized mixed-effects logistic regression... There was considerable variation among the words and the children, but between-word variability was larger in magnitude than between-child variability. There was a clear positive effect of target word... Word frequency and neighborhood competition both had an effect on intelligibility in young children's speech, so listener expectations are an important factor in the selection of items for children's ...

Humans Child, Preschool Adult Speech Linguistics +4 autres

Intelligibility of speech produced by sighted and blind adults.

2022

DOI: 10.1371/journal.pone.0272127 PMID: 36107945

It is well known that speech uses both the auditory and visual modalities to convey information. In cases of congenital sensory deprivation, the feedback language learners have access to for mapping v... Twenty adult listeners performed two perceptual identification tasks in which vowels produced by congenitally blind adults and sighted adults were used as stimuli. The vowels were presented in the aud... The results showed that, although blind speakers did not differ from their sighted peers in the auditory modality, they had lower scores in the audiovisual and visual modalities. Some vowels produced ... Together, the results suggest that adult blind speakers have learned to adapt to their sensory loss so that they can successfully achieve intelligible vowel targets in non-noisy conditions but that th...

Blindness Canada Humans Speech Acoustics Speech Intelligibility +2 autres

Foreign Accented-Speech and Perceptions of Confidence and Intelligence.

Aug 2023

DOI: 10.1007/s10936-023-09940-9 PMID: 36867293

The purpose of the current study is to explore listeners' perception of accented speech in terms of confidence and intelligence. To this end, three groups of listeners were asked to rate speakers of E...

Humans Speech Perception Speech Intelligibility Language Cognition +1 autres

Intelligibility improves perception of timing changes in speech.

2023

DOI: 10.1371/journal.pone.0279024 PMID: 36634109

Auditory rhythms are ubiquitous in music, speech, and other everyday sounds. Yet, it is unclear how perceived rhythms arise from the repeating structure of sounds. For speech, it is unclear whether rh...

Humans Speech Intelligibility Speech Perception Phonetics Acoustics +3 autres

Beyond Speech Intelligibility: Quantifying Behavioral and Perceived Listening Effort in Response to Dysarthric Speech.

17 11 2022

DOI: 10.1044/2022_JSLHR-22-00136 PMID: 36198057

This study investigated whether listener processing of dysarthric speech requires the recruitment of more cognitive resources (i.e., higher levels of listening effort) than neurotypical speech. We als... A word recall paradigm was used to index behavioral listening effort. The primary task involved word transcription, whereas a memory task involved recalling words from previous sentences. Nineteen lis... Results revealed significant effects of dysarthria on the likelihood of correct word recall, indicating that the transcription of dysarthric speech required higher levels of behavioral listening effor... Results suggest that cognitive resources, particularly listeners' working memory capacity, are more taxed when deciphering dysarthric versus neurotypical speech. An increased demand on these resources...

Humans Speech Intelligibility Dysarthria Speech Perception Listening Effort +1 autres

Validity of Off-the-Shelf Automatic Speech Recognition for Assessing Speech Intelligibility and Speech Severity in Speakers With Amyotrophic Lateral Sclerosis.

08 06 2022

DOI: 10.1044/2022_JSLHR-21-00589 PMID: 35623334

There is increasing interest in using automatic speech recognition (ASR) systems to evaluate impairment severity or speech intelligibility in speakers with dysarthria. We assessed the clinical validit... Using speech samples collected from 52 individuals with ALS and 20 healthy control speakers, we compared word recognition rate (WRR) from the commercially available Google Cloud ASR API (Machine WRR) ... Human WRR achieved better accuracy than Machine WRR when indexing speech severity, and, although related, Human and Machine WRR were not strongly correlated. When the speech signal was mixed with nois... Results indicated that the OTS ASR system was inadequate for early detection of speech impairment and grading overall speech severity. While Machine and Human WRR were correlated, ASR should not be us...

Amyotrophic Lateral Sclerosis Dysarthria Humans Reproducibility of Results Speech Disorders +3 autres

Chimiokines CXC : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Chimiokine CXCL1

Chimiokine CXCL16

Chimiokine CXCL5

Chimiokine CXCL6

Chimiokine CXCL9

Chimiokine CXCL10

Chimiokine CXCL11

Chimiokine CXCL12

Chimiokine CXCL13

Facteur-4 plaquettaire

Auteurs principaux

Sources (10000 au total)