Communication autocrine : Questions médicales fréquentes
Nom anglais: Autocrine Communication
Descriptor UI:D019898
Tree Number:G04.085.100
Termes MeSH sélectionnés :
Cholangitis
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"name": "Comment diagnostiquer une communication autocrine ?",
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"text": "Le diagnostic repose sur des tests biologiques et des analyses de signalisation cellulaire."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer la communication autocrine ?",
"position": 2,
"acceptedAnswer": {
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"text": "Des tests de culture cellulaire et des dosages de cytokines peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des marqueurs spécifiques pour la communication autocrine ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des marqueurs comme les récepteurs de cytokines peuvent indiquer une communication autocrine."
}
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{
"@type": "Question",
"name": "La communication autocrine est-elle visible par imagerie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle n'est généralement pas visible par imagerie, mais des techniques avancées peuvent aider."
}
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{
"@type": "Question",
"name": "Quels sont les signes d'une dérégulation autocrine ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes incluent une croissance cellulaire anormale ou une inflammation persistante."
}
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{
"@type": "Question",
"name": "Quels symptômes indiquent une communication autocrine anormale ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes peuvent inclure des douleurs, des inflammations ou des tumeurs."
}
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{
"@type": "Question",
"name": "La communication autocrine affecte-t-elle le métabolisme ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut influencer le métabolisme cellulaire et provoquer des déséquilibres."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques liés à l'autocrine dans le cancer ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme la fatigue et la perte de poids peuvent être présents."
}
},
{
"@type": "Question",
"name": "Comment la communication autocrine influence-t-elle l'immunité ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut moduler la réponse immunitaire, entraînant une inflammation ou une immunosuppression."
}
},
{
"@type": "Question",
"name": "Des symptômes neurologiques peuvent-ils être liés à l'autocrine ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles neurologiques peuvent survenir en raison de la signalisation autocrine."
}
},
{
"@type": "Question",
"name": "Comment prévenir les dérégulations autocrines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir ces dérégulations."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques pour le cancer ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, éviter les carcinogènes et maintenir un poids santé sont des mesures préventives."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il à réguler l'autocrine ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut moduler la signalisation autocrine et améliorer la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il la communication autocrine ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut perturber la communication autocrine et affecter la santé."
}
},
{
"@type": "Question",
"name": "Des compléments alimentaires peuvent-ils aider ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains compléments, comme les oméga-3, peuvent moduler la communication autocrine."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent la communication autocrine ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des inhibiteurs de signalisation peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils moduler la communication autocrine ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent inhiber ou stimuler la signalisation autocrine."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements spécifiques pour le cancer liés à l'autocrine ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements comme les anticorps monoclonaux ciblent souvent la communication autocrine dans le cancer."
}
},
{
"@type": "Question",
"name": "Comment la thérapie génique influence-t-elle l'autocrine ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique peut corriger des dérégulations dans la communication autocrine."
}
},
{
"@type": "Question",
"name": "Les traitements hormonaux affectent-ils la communication autocrine ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements hormonaux peuvent influencer la signalisation autocrine dans certaines pathologies."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent résulter d'une communication autocrine anormale ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des cancers, des maladies auto-immunes et des inflammations chroniques."
}
},
{
"@type": "Question",
"name": "La communication autocrine peut-elle entraîner des troubles métaboliques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une dérégulation peut provoquer des troubles métaboliques comme le diabète."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'inflammation chronique ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une communication autocrine anormale peut entraîner une inflammation chronique."
}
},
{
"@type": "Question",
"name": "Comment la communication autocrine affecte-t-elle le cancer ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut favoriser la croissance tumorale et la résistance aux traitements anticancéreux."
}
},
{
"@type": "Question",
"name": "Des complications neurologiques sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dérégulations peuvent entraîner des troubles neurologiques et cognitifs."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de dérégulation autocrine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'âge, l'obésité, le tabagisme et l'exposition à des toxines."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle la communication autocrine ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en sucres et graisses peut perturber la signalisation autocrine."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut augmenter le risque de dérégulation autocrine."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines mutations génétiques peuvent prédisposer à des dérégulations autocrines."
}
},
{
"@type": "Question",
"name": "L'exposition à des produits chimiques est-elle un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des produits chimiques toxiques peut augmenter le risque de dérégulation."
}
}
]
}
]
}
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a female predisposition and selective destruction of intrahepatic small bile ducts leading to nonsuppurative destructive cholangit...
Frequent post-operative cholangitis in biliary atresia (BA) affects the long-term native liver survival. This study assessed the characteristics of early cholangitis and their influence on the prognos...
Forty-three patients with BA who underwent surgery between 2000 and 2020 were analyzed for routine inflammatory markers. Early cholangitis characteristics were compared between native liver survivor (...
Among the 43 patients, 30 (69.8%) experienced 130 episodes of cholangitis. In the area under the receiver operating characteristics curve (AUROC) analysis, the cutoff value of the total cholangitis ep...
Cholangitis in the NLS group was lymphocyte-dominant and atypical in its pathogenesis. Lymphocyte-dominant cholangitis is non-suppurative, and future research should clarify its pathogenesis to improv...
Primary biliary cholangitis (PBC) is an archetypal autoimmune disease. Chronic lymphocytic cholangitis is associated with interface hepatitis, ductopenia, cholestasis, and progressive biliary fibrosis...
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the presence of antimitochond...
Primary biliary cholangitis (PBC) is a complex, chronic disease with a heterogeneous presentation, disease progression, and response to therapy. Several prognostic models based on disease stage and/or...
Few studies are available on older patients with acute cholangitis. In this study, we aimed to examine the clinical characteristics of older patients with acute cholangitis....
Patients aged 65 years and over who were diagnosed with acute cholangitis between February 2019 and August 2022 were analyzed retrospectively. Patients eligible for the study were divided into two gro...
Of a total of 309 enrolled patients, 120 (38.8%) were in the octogenarian group and 189 (61.2%) were in the non-octogenarian group. The mean age was 77.2 ± 8.0 years and 51.8% were women. Severe disea...
Among older patients with acute cholangitis, clinicians should closely monitor those aged 80 years and over, as well as those with malignant etiology and hypoalbuminemia, due to their high risk of ser...
There is a paucity in the literature in regard to the incidence, risk factors, and outcomes for post-operative cholangitis following hepatic resection....
Retrospective review of the ACS NSQIP main and targeted hepatectomy registries for 2012-2016....
A total of 11,243 cases met the selection criteria. The incidence of post-operative cholangitis was 0.64% (151 cases). Multivariate analysis identified several risk factors associated with the develop...
Largest analysis of post-operative cholangitis following hepatic resection. While a rare occurrence, it is associated with significantly increased risk for severe morbidity and mortality. The most sig...
Metabolic dysfunctions, particularly hyperlipidemia, are a common finding in Primary Biliary Cholangitis (PBC). In presence of metabolic components of fatty-liver-disease (MAFLD), the liver fibrosis p...
In a prospective, multicenter study 107 PBC patients were enrolled; among these, 54 subjects were age-and sex-matched with 54 controls with a propensity-score-matching-analysis. Eating habits and phys...
The total fat intake was higher in controls than in PBC (p=0.004), unless above the national recommendations in both groups. Moreover, in PBC monounsaturated-fat and polyunsaturated-fatty-acid intakes...
The lifestyle of both PBC and controls is at high risk of developing MAFLD. Therefore, hepatologists should regularly evaluate eating habits and physical activity in PBC patients and promote a lifesty...
IgG4-related cholangitis (IRC) is the major hepatobiliary manifestation of IgG4-related disease (IgG4-RD), a systemic fibroinflammatory disorder. The pathogenesis of IgG4-RD and IRC is currently viewe...
Cholangitis is a late complication after pancreatoduodenectomy with considerable clinical impact and is difficult to treat. The aim of this systematic review was to provide an overview of the literatu...
A systematic search of the databases PUBMED and EMBASE was performed to identify all studies reporting on possible risk factors for cholangitis following pancreatoduodenectomy. Data on patient, peri- ...
In total, 464 studies were identified. Eight studies met the inclusion criteria for this analysis. The definition of postoperative cholangitis was inconsistent, with four studies using the Tokyo Guide...
Multiple potential risk factors for postoperative cholangitis were identified, with large discrepancies between studies. Prospective research, with consensus on the definition, is required to determin...