{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Protéine G cdc42 : Questions médicales les plus fréquentes",
"headline": "Protéine G cdc42 : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Protéine G cdc42 : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-02-21",
"dateModified": "2025-05-16",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Protéine G cdc42"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Protéines G rho",
"url": "https://questionsmedicales.fr/mesh/D020741",
"about": {
"@type": "MedicalCondition",
"name": "Protéines G rho",
"code": {
"@type": "MedicalCode",
"code": "D020741",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.476.338.400.700"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Protéine G cdc42",
"alternateName": "cdc42 GTP-Binding Protein",
"code": {
"@type": "MedicalCode",
"code": "D020764",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Jeong Woo Park",
"url": "https://questionsmedicales.fr/author/Jeong%20Woo%20Park",
"affiliation": {
"@type": "Organization",
"name": "Department of Biological Science, University of Ulsan, Ulsan, 44610, South Korea."
}
},
{
"@type": "Person",
"name": "Ming Huang",
"url": "https://questionsmedicales.fr/author/Ming%20Huang",
"affiliation": {
"@type": "Organization",
"name": "Environmental Toxicology Graduate Program, University of California, Riverside, Riverside, California 92521, United States."
}
},
{
"@type": "Person",
"name": "Yinsheng Wang",
"url": "https://questionsmedicales.fr/author/Yinsheng%20Wang",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, University of California, Riverside, Riverside, California 92521, United States."
}
},
{
"@type": "Person",
"name": "Natsumi Maruta",
"url": "https://questionsmedicales.fr/author/Natsumi%20Maruta",
"affiliation": {
"@type": "Organization",
"name": "Plant Genetic Engineering Laboratory, School of Agriculture and Food Sciences, University of Queensland, Brisbane, QLD, 4072, Australia."
}
},
{
"@type": "Person",
"name": "Yuri Trusov",
"url": "https://questionsmedicales.fr/author/Yuri%20Trusov",
"affiliation": {
"@type": "Organization",
"name": "Plant Genetic Engineering Laboratory, School of Agriculture and Food Sciences, University of Queensland, Brisbane, QLD, 4072, Australia."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Network Meta-analysis of Different Treatments for Vestibular Migraine.",
"datePublished": "2023-09-07",
"url": "https://questionsmedicales.fr/article/37676473",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s40263-023-01037-0"
}
},
{
"@type": "ScholarlyArticle",
"name": "Preventive Medications in Pediatric Migraine: A Network Meta-Analysis.",
"datePublished": "2024-10-01",
"url": "https://questionsmedicales.fr/article/39388181",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1001/jamanetworkopen.2024.38666"
}
},
{
"@type": "ScholarlyArticle",
"name": "Efficacy of Laser in Hair Removal: A Network Meta-analysis.",
"datePublished": "2023-07-26",
"url": "https://questionsmedicales.fr/article/37493187",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1080/14764172.2023.2221838"
}
},
{
"@type": "ScholarlyArticle",
"name": "A network meta-analysis of arthroscopic rotator cuff repair.",
"datePublished": "2023-07-13",
"url": "https://questionsmedicales.fr/article/37443010",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s12893-023-02078-4"
}
},
{
"@type": "ScholarlyArticle",
"name": "Treatment of children with infantile spasms: A network meta-analysis.",
"datePublished": "2022-06-29",
"url": "https://questionsmedicales.fr/article/35765990",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1111/dmcn.15330"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Protéines et peptides de signalisation intracellulaire",
"item": "https://questionsmedicales.fr/mesh/D047908"
},
{
"@type": "ListItem",
"position": 5,
"name": "Protéines G",
"item": "https://questionsmedicales.fr/mesh/D019204"
},
{
"@type": "ListItem",
"position": 6,
"name": "Protéines G monomériques",
"item": "https://questionsmedicales.fr/mesh/D020559"
},
{
"@type": "ListItem",
"position": 7,
"name": "Protéines G rho",
"item": "https://questionsmedicales.fr/mesh/D020741"
},
{
"@type": "ListItem",
"position": 8,
"name": "Protéine G cdc42",
"item": "https://questionsmedicales.fr/mesh/D020764"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Protéine G cdc42 - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Protéine G cdc42",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-19",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Protéine G cdc42",
"description": "Comment diagnostiquer une dysfonction de cdc42 ?\nQuels tests sont utilisés pour cdc42 ?\nY a-t-il des biomarqueurs pour cdc42 ?\nQuels symptômes indiquent un problème avec cdc42 ?\nPeut-on détecter cdc42 dans des échantillons biologiques ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Protéine G cdc42",
"description": "Quels sont les symptômes d'une mutation de cdc42 ?\nComment cdc42 affecte-t-il la cellule ?\nY a-t-il des signes cliniques associés à cdc42 ?\nCdc42 est-il lié à des maladies spécifiques ?\nQuels effets cdc42 a-t-il sur le cytosquelette ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Protéine G cdc42",
"description": "Peut-on prévenir les mutations de cdc42 ?\nY a-t-il des mesures préventives pour les maladies liées à cdc42 ?\nComment le mode de vie influence-t-il cdc42 ?\nLes tests génétiques peuvent-ils prévenir des problèmes avec cdc42 ?\nY a-t-il des recommandations diététiques pour cdc42 ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Protéine G cdc42",
"description": "Quels traitements ciblent cdc42 ?\nPeut-on utiliser des thérapies géniques pour cdc42 ?\nY a-t-il des médicaments pour moduler cdc42 ?\nComment la recherche avance-t-elle sur cdc42 ?\nLes traitements sont-ils efficaces contre cdc42 ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Protéine G cdc42",
"description": "Quelles complications sont liées à cdc42 ?\nCdc42 peut-il entraîner des problèmes neurologiques ?\nY a-t-il des complications à long terme avec cdc42 ?\nComment cdc42 affecte-t-il le système immunitaire ?\nLes complications de cdc42 sont-elles réversibles ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Protéine G cdc42",
"description": "Quels sont les facteurs de risque pour cdc42 ?\nL'exposition à des toxines affecte-t-elle cdc42 ?\nLes antécédents familiaux augmentent-ils le risque ?\nLe stress peut-il affecter cdc42 ?\nY a-t-il des groupes à risque pour cdc42 ?",
"url": "https://questionsmedicales.fr/mesh/D020764?mesh_terms=Network+Meta-Analysis&page=2#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une dysfonction de cdc42 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses de signalisation cellulaire peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour cdc42 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent l'immunoblotting et la microscopie à fluorescence."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs pour cdc42 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de biomarqueurs spécifiques pour cdc42."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème avec cdc42 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies dans la migration cellulaire et la morphogenèse peuvent être observées."
}
},
{
"@type": "Question",
"name": "Peut-on détecter cdc42 dans des échantillons biologiques ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, cdc42 peut être détecté dans des échantillons de tissus ou de cellules."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une mutation de cdc42 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les mutations peuvent entraîner des troubles de la migration cellulaire et des malformations."
}
},
{
"@type": "Question",
"name": "Comment cdc42 affecte-t-il la cellule ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cdc42 régule la forme et le mouvement des cellules, influençant leur fonction."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques associés à cdc42 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies dans le développement et la motilité cellulaire peuvent être observées."
}
},
{
"@type": "Question",
"name": "Cdc42 est-il lié à des maladies spécifiques ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies de cdc42 sont associées à des cancers et des maladies génétiques."
}
},
{
"@type": "Question",
"name": "Quels effets cdc42 a-t-il sur le cytosquelette ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cdc42 joue un rôle clé dans la régulation du cytosquelette, influençant la forme cellulaire."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les mutations de cdc42 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention des mutations génétiques est complexe et dépend de facteurs environnementaux."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives pour les maladies liées à cdc42 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des conseils génétiques peuvent aider à évaluer le risque de maladies liées à cdc42."
}
},
{
"@type": "Question",
"name": "Comment le mode de vie influence-t-il cdc42 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire le risque de maladies associées à cdc42."
}
},
{
"@type": "Question",
"name": "Les tests génétiques peuvent-ils prévenir des problèmes avec cdc42 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests génétiques peuvent identifier les porteurs de mutations de cdc42."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations diététiques pour cdc42 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire, mais n'affecte pas directement cdc42."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent cdc42 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques de cdc42 sont en cours de développement pour le cancer."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des thérapies géniques pour cdc42 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est une approche potentielle pour corriger les mutations de cdc42."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments pour moduler cdc42 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des composés chimiques sont en cours d'évaluation pour moduler l'activité de cdc42."
}
},
{
"@type": "Question",
"name": "Comment la recherche avance-t-elle sur cdc42 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La recherche se concentre sur les inhibiteurs et les voies de signalisation associées."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces contre cdc42 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité des traitements dépend du type de maladie et de la mutation spécifique."
}
},
{
"@type": "Question",
"name": "Quelles complications sont liées à cdc42 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles du développement et des cancers."
}
},
{
"@type": "Question",
"name": "Cdc42 peut-il entraîner des problèmes neurologiques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies de cdc42 sont associées à des troubles neurologiques dans certains cas."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme avec cdc42 ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications à long terme peuvent inclure des cancers et des malformations congénitales."
}
},
{
"@type": "Question",
"name": "Comment cdc42 affecte-t-il le système immunitaire ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cdc42 peut influencer la réponse immunitaire, mais les effets varient selon les contextes."
}
},
{
"@type": "Question",
"name": "Les complications de cdc42 sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour cdc42 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques et des influences environnementales."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines affecte-t-elle cdc42 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines toxines environnementales peuvent influencer l'expression de cdc42."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux augmentent-ils le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Le stress peut-il affecter cdc42 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut influencer la signalisation cellulaire, y compris celle de cdc42."
}
},
{
"@type": "Question",
"name": "Y a-t-il des groupes à risque pour cdc42 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les individus avec des mutations génétiques spécifiques sont à risque accru."
}
}
]
}
]
}
Although one of the major presentations of vestibular migraine is dizziness with/without unsteady gait, it is still classified as one of the migraine categories. However, in contrast to ordinary migra...
The objective of this current network meta-analysis (NMA) was to compare the efficacy and acceptability of individual treatment strategies in patients with vestibular migraine....
The PubMed, Embase, ScienceDirect, ProQuest, Web of Science, ClinicalKey, Cochrane Central, and ClinicalTrials.gov databases were systematically searched for randomized controlled trials (RCTs), with ...
Seven randomized controlled trials (N = 828, mean age 37.6 years, 78.4% female) and seven active regimens were included. We determined that only valproic acid (standardized mean difference [SMD] -1.61...
The current study provides evidence that only valproic acid, propranolol, and venlafaxine might be associated with beneficial efficacy in vestibular migraine treatment....
CRD42023388343....
Pediatric migraine substantially impacts quality of life and academic performance among children and adolescents. Understanding the efficacy and safety of pharmacological interventions for migraine pr...
To conduct a comprehensive network meta-analysis to evaluate the efficacy and safety associated with pharmacological treatments for pediatric migraine prophylaxis among pediatric patients with a migra...
PubMed, Embase, and SCOPUS were searched for publications up to September 2023. Search terms and indexing were chosen to encompass relevant studies, focusing on randomized clinical trials in pediatric...
Inclusion criteria targeted randomized clinical trials involving pediatric patients with migraine. Studies were selected based on their examination of oral pharmacological interventions. The search yi...
Data extraction adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines. Five investigators independently extracted study data into a spreadsheet in duplicat...
The primary outcome was migraine frequency (number of attacks per month). Secondary outcomes included a 50% or greater responder rate, headache duration, headache intensity, and disability (assessed b...
The analysis incorporated 45 trials with 3771 participants. Compared with placebo, pregabalin (ratio of means [RoM], 0.38; 95% CI, 0.18-0.79) and topiramate with vitamin D3 (RoM, 0.44; 95% CI, 0.30-0....
In this network meta-analysis of randomized clinical trials, topiramate and pregabalin were associated with reduction in headache frequency and intensity. Although there were also other drugs that sho...
Laser hair removal is an increasingly prevalent trend of cosmetic procedures. The purpose of this study was to assess the effectiveness of hair reduction among several types of laser interventions....
The selected studies searched in PubMed and EMBASE were assessed for quality of evidence, and extracted data on absolute hair count and hair reduction rate. Qualitative data were synthesized using sta...
A total of 13 randomized controlled trials (RCTs) (...
Eliminating unwanted hair with lasers or intense pulsed light is safe and effective; however, which type of intervention is more beneficial in the long-term process should be studied with a longer fol...
Rotator cuff tear is a common shoulder injury that often leads to serious limitations in daily life. Herein, a network Meta-analysis using frequency theory was performed to evaluate the clinical outco...
PubMed, EMbase, The Cochrane Library, and Web of Science were searched for randomized controlled trials and cohort studies comparing rotator cuff repair techniques published from inception to May 2022...
A total of 51 articles were finally included, including 27 randomized controlled trials and 24 cohort studies. Results from the network Meta-analysis showed that: (1) In terms of the American Shoulder...
Based on the results of network Meta-analysis and surface under the cumulative ranking, platelet-rich plasma therapy, bone marrow stimulation, and double-row repair have good overall rehabilitation ef...
We performed a systematic review and network meta-analysis (NMA) to obtain comparative effectiveness estimates and rankings of non-surgical interventions used to treat infantile spasms....
All randomized controlled trials (RCTs) including children 2 months to 3 years of age with infantile spasms (with hypsarrhythmia or hypsarrhythmia variants on electroencephalography) receiving appropr...
Twenty-two RCTs comparing first-line treatments for infantile spasms were reviewed; of these, 17 were included in the NMA. Both frequentist and Bayesian network rankings for electroclinical remission ...
Treatments including ACTH and high dose prednisolone are more effective in achieving electroclinical and clinical remissions for infantile spasms....
Adrenocorticotropic hormone and high dose prednisolone are more effective than other medications for infantile spasms. Symptomatic etiology decreases the likelihood of remission even after adjusting f...
Barrett's esophagus (BE) is a precancerous condition that has the potential to develop into esophageal cancer (EC). Currently, there is a wide range of management options available for individuals at ...
Data extracted from eligible randomized controlled trials were utilized in a Bayesian network meta-analysis to examine the relative effectiveness of BE's treatment regimens and determine their ranking...
We identified twenty-three RCT studies with a total of 1675 participants, and ten different interventions. Regarding complete ablation of non-dysplastic BE, the comparative effectiveness ranking indic...
Endoscopic surveillance alone or PPI/H2RA alone may not be sufficient for managing BE, even in cases of non-dysplastic BE. However, APC has shown excellent efficacy in treating non-dysplastic BE. For ...
The aim of this systematic review and network meta-analysis (NMA) of randomized controlled trials was to evaluate the effectiveness of treatments for pain relief of burning mouth syndrome (BMS). Five ...
Diabetic kidney disease (DKD) is a health burden of rising importance. Slowing progression to end stage kidney disease is the main goal of drug treatment. The aim of this analysis is to compare drug t...
We searched Medline, CENTRAL and clinicaltrials.gov for randomized, controlled studies including adults with DKD treated with the following drugs of interest: single angiotensin-converting-enzyme-inhi...
Of initial 3489 publications, 38 clinical trials were found eligible, in total including 42346 patients. Concerning the primary endpoints overall mortality and end stage kidney disease, SGLT2i on top ...
As the only drug class, SGLT2i showed in our analysis beneficial effects on top of ACEi/ARB treatment regarding mortality and end stage kidney disease and by that reconfirmed its position as treatment...
Despite the introduction of various pharmaceutical therapies for treating obesity, selecting the optimal treatment remains challenging for both patients and physicians. Therefore, in this network meta...
International databases, including PubMed, Web of Science, Scopus, Cochrane Library, and Embase, were searched for studies published from database inception to April 2023. The consistency assumption w...
Of 9519 retrieved references, 96 randomized controlled trials, including 68 with both men and women, 23 with women only, and 5 with men only, met the eligibility criteria for this study. There were 4 ...
According to the results of this NMA, semaglutide seems to be an effective treatment option for both men and women, whereas beloranib appears to be particularly effective for women with obesity and ov...
Network meta-analysis (NMA) allows estimating and ranking the effects of several interventions for a clinical condition. Component network meta-analysis (CNMA) is an extension of NMA which considers t...
We evaluate a forward model selection strategy for component network meta-analysis to relax the additivity assumption that can be used in connected or disconnected networks. In addition, we describe a...
CNMA models provide good performance for connected networks and can be an alternative to standard NMA if additivity holds. For disconnected networks, we recommend to use additive CNMA only if strong c...
CNMA methods are feasible for connected networks but questionable for disconnected networks....