Titre : Récepteur facteur neurotrophique ciliaire

Récepteur facteur neurotrophique ciliaire : Questions médicales fréquentes

Termes MeSH sélectionnés :

Language Development Disorders
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Récepteur facteur neurotrophique ciliaire : Questions médicales les plus fréquentes", "headline": "Récepteur facteur neurotrophique ciliaire : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Récepteur facteur neurotrophique ciliaire : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-04-06", "dateModified": "2025-04-01", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Récepteur facteur neurotrophique ciliaire" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Récepteurs facteur croissance nerf", "url": "https://questionsmedicales.fr/mesh/D017475", "about": { "@type": "MedicalCondition", "name": "Récepteurs facteur croissance nerf", "code": { "@type": "MedicalCode", "code": "D017475", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.543.750.750.400.550" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Sous-unité alpha du récepteur du facteur neurotrophique ciliaire", "alternateName": "Ciliary Neurotrophic Factor Receptor alpha Subunit", "url": "https://questionsmedicales.fr/mesh/D053739", "about": { "@type": "MedicalCondition", "name": "Sous-unité alpha du récepteur du facteur neurotrophique ciliaire", "code": { "@type": "MedicalCode", "code": "D053739", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.543.750.750.400.550.250.249" } } }, { "@type": "MedicalWebPage", "name": "Récepteur gp130 de cytokines", "alternateName": "Cytokine Receptor gp130", "url": "https://questionsmedicales.fr/mesh/D050822", "about": { "@type": "MedicalCondition", "name": "Récepteur gp130 de cytokines", "code": { "@type": "MedicalCode", "code": "D050822", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.543.750.750.400.550.250.500" } } }, { "@type": "MedicalWebPage", "name": "Sous-unité alpha du récepteur au facteur d'inhibition de la leucémie", "alternateName": "Leukemia Inhibitory Factor Receptor alpha Subunit", "url": "https://questionsmedicales.fr/mesh/D053680", "about": { "@type": "MedicalCondition", "name": "Sous-unité alpha du récepteur au facteur d'inhibition de la leucémie", "code": { "@type": "MedicalCode", "code": "D053680", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.543.750.750.400.550.250.750" } } } ], "about": { "@type": "MedicalCondition", "name": "Récepteur facteur neurotrophique ciliaire", "alternateName": "Receptor, Ciliary Neurotrophic Factor", "code": { "@type": "MedicalCode", "code": "D020801", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Giovanni Tossetta", "url": "https://questionsmedicales.fr/author/Giovanni%20Tossetta", "affiliation": { "@type": "Organization", "name": "Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy." } }, { "@type": "Person", "name": "Antonio Giordano", "url": "https://questionsmedicales.fr/author/Antonio%20Giordano", "affiliation": { "@type": "Organization", "name": "Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy." } }, { "@type": "Person", "name": "Cuihong Jia", "url": "https://questionsmedicales.fr/author/Cuihong%20Jia", "affiliation": { "@type": "Organization", "name": "Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA. Electronic address: jiac01@etsu.edu." } }, { "@type": "Person", "name": "Theo Hagg", "url": "https://questionsmedicales.fr/author/Theo%20Hagg", "affiliation": { "@type": "Organization", "name": "Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA." } }, { "@type": "Person", "name": "Jessica Perugini", "url": "https://questionsmedicales.fr/author/Jessica%20Perugini", "affiliation": { "@type": "Organization", "name": "Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "The Engage with Developmental Language Disorder (E-DLD) project: Cohort profile.", "datePublished": "2022-12-24", "url": "https://questionsmedicales.fr/article/36565246", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1111/1460-6984.12835" } }, { "@type": "ScholarlyArticle", "name": "Development and Validation of a Language Screening for Implementation in Pre-School Settings.", "datePublished": "2022-06-22", "url": "https://questionsmedicales.fr/article/35812510", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3389/fpubh.2022.866598" } }, { "@type": "ScholarlyArticle", "name": "Identifying Language Disorder in Bilingual Children Using Automatic Speech Recognition.", "datePublished": "2022-07-12", "url": "https://questionsmedicales.fr/article/35858259", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1044/2022_JSLHR-21-00667" } }, { "@type": "ScholarlyArticle", "name": "Describing the Spoken Language Skills of Typically Developing Afrikaans-Speaking Children Using Language Sample Analysis: A Pilot Study.", "datePublished": "2023-02-14", "url": "https://questionsmedicales.fr/article/36787151", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1044/2022_LSHSS-22-00077" } }, { "@type": "ScholarlyArticle", "name": "The impact of developmental language disorder in a defendant's description on mock jurors' perceptions and judgements.", "datePublished": "2022-09-10", "url": "https://questionsmedicales.fr/article/36087284", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1111/1460-6984.12779" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Acides aminés, peptides et protéines", "item": "https://questionsmedicales.fr/mesh/D000602" }, { "@type": "ListItem", "position": 3, "name": "Protéines", "item": "https://questionsmedicales.fr/mesh/D011506" }, { "@type": "ListItem", "position": 4, "name": "Protéines membranaires", "item": "https://questionsmedicales.fr/mesh/D008565" }, { "@type": "ListItem", "position": 5, "name": "Récepteurs de surface cellulaire", "item": "https://questionsmedicales.fr/mesh/D011956" }, { "@type": "ListItem", "position": 6, "name": "Récepteurs peptidiques", "item": "https://questionsmedicales.fr/mesh/D018000" }, { "@type": "ListItem", "position": 7, "name": "Récepteur facteur croissance", "item": "https://questionsmedicales.fr/mesh/D017978" }, { "@type": "ListItem", "position": 8, "name": "Récepteurs facteur croissance nerf", "item": "https://questionsmedicales.fr/mesh/D017475" }, { "@type": "ListItem", "position": 9, "name": "Récepteur facteur neurotrophique ciliaire", "item": "https://questionsmedicales.fr/mesh/D020801" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Récepteur facteur neurotrophique ciliaire - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Récepteur facteur neurotrophique ciliaire", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-07", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Récepteur facteur neurotrophique ciliaire", "description": "Comment diagnostiquer une dysfonction du récepteur CNTF ?\nQuels examens sont utilisés pour évaluer le récepteur CNTF ?\nY a-t-il des biomarqueurs pour le récepteur CNTF ?\nLe diagnostic nécessite-t-il une biopsie ?\nQuels symptômes peuvent indiquer un problème avec le CNTF ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Récepteur facteur neurotrophique ciliaire", "description": "Quels sont les symptômes d'une déficience en CNTF ?\nLa douleur neuropathique est-elle liée au CNTF ?\nPeut-on observer des troubles moteurs avec le CNTF ?\nLes troubles sensoriels sont-ils associés au CNTF ?\nY a-t-il des signes cliniques spécifiques au CNTF ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Récepteur facteur neurotrophique ciliaire", "description": "Peut-on prévenir les troubles liés au CNTF ?\nY a-t-il des mesures préventives spécifiques ?\nL'exercice régulier aide-t-il à prévenir les troubles du CNTF ?\nUne alimentation équilibrée peut-elle aider ?\nLe stress a-t-il un impact sur le CNTF ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Récepteur facteur neurotrophique ciliaire", "description": "Quels traitements sont disponibles pour les troubles du CNTF ?\nLes thérapies géniques peuvent-elles aider le CNTF ?\nLes médicaments anti-inflammatoires sont-ils efficaces ?\nLa physiothérapie est-elle recommandée ?\nY a-t-il des traitements expérimentaux pour le CNTF ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Récepteur facteur neurotrophique ciliaire", "description": "Quelles complications peuvent survenir avec le CNTF ?\nLe CNTF peut-il entraîner des troubles cognitifs ?\nY a-t-il un risque de dépendance aux médicaments ?\nLes complications sont-elles réversibles ?\nLe CNTF peut-il affecter la qualité de vie ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Récepteur facteur neurotrophique ciliaire", "description": "Quels sont les facteurs de risque pour les troubles du CNTF ?\nL'âge est-il un facteur de risque pour le CNTF ?\nLe sexe influence-t-il le risque de troubles du CNTF ?\nLes infections peuvent-elles augmenter le risque ?\nLe mode de vie influence-t-il le risque de troubles ?", "url": "https://questionsmedicales.fr/mesh/D020801?mesh_terms=Language+Development+Disorders&page=4#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysfonction du récepteur CNTF ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des tests neurologiques et des analyses génétiques." } }, { "@type": "Question", "name": "Quels examens sont utilisés pour évaluer le récepteur CNTF ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des IRM et des électromyogrammes peuvent être utilisés pour évaluer la fonction nerveuse." } }, { "@type": "Question", "name": "Y a-t-il des biomarqueurs pour le récepteur CNTF ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de biomarqueurs spécifiques pour le récepteur CNTF." } }, { "@type": "Question", "name": "Le diagnostic nécessite-t-il une biopsie ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Une biopsie n'est généralement pas nécessaire pour diagnostiquer les troubles liés au CNTF." } }, { "@type": "Question", "name": "Quels symptômes peuvent indiquer un problème avec le CNTF ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme la faiblesse musculaire ou des douleurs neuropathiques peuvent indiquer un problème." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une déficience en CNTF ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent faiblesse musculaire, douleurs chroniques et troubles sensoriels." } }, { "@type": "Question", "name": "La douleur neuropathique est-elle liée au CNTF ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le CNTF joue un rôle dans la modulation de la douleur neuropathique." } }, { "@type": "Question", "name": "Peut-on observer des troubles moteurs avec le CNTF ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles moteurs peuvent survenir en raison d'une dysfonction du CNTF." } }, { "@type": "Question", "name": "Les troubles sensoriels sont-ils associés au CNTF ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles sensoriels peuvent être observés en cas de dysfonction du CNTF." } }, { "@type": "Question", "name": "Y a-t-il des signes cliniques spécifiques au CNTF ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des signes comme l'hypersensibilité ou l'engourdissement peuvent être spécifiques." } }, { "@type": "Question", "name": "Peut-on prévenir les troubles liés au CNTF ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives spécifiques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les traumatismes nerveux et gérer les maladies chroniques peut aider." } }, { "@type": "Question", "name": "L'exercice régulier aide-t-il à prévenir les troubles du CNTF ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exercice régulier peut renforcer les muscles et améliorer la santé nerveuse." } }, { "@type": "Question", "name": "Une alimentation équilibrée peut-elle aider ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en nutriments favorise la santé nerveuse et musculaire." } }, { "@type": "Question", "name": "Le stress a-t-il un impact sur le CNTF ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut affecter la fonction nerveuse et aggraver les symptômes." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour les troubles du CNTF ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des thérapies médicamenteuses et des interventions physiques." } }, { "@type": "Question", "name": "Les thérapies géniques peuvent-elles aider le CNTF ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches sont en cours sur l'utilisation de thérapies géniques pour cibler le CNTF." } }, { "@type": "Question", "name": "Les médicaments anti-inflammatoires sont-ils efficaces ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent réduire l'inflammation et améliorer les symptômes liés au CNTF." } }, { "@type": "Question", "name": "La physiothérapie est-elle recommandée ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la physiothérapie peut aider à améliorer la fonction musculaire et réduire la douleur." } }, { "@type": "Question", "name": "Y a-t-il des traitements expérimentaux pour le CNTF ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements expérimentaux, comme les thérapies biologiques, sont en cours d'évaluation." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec le CNTF ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent la progression des troubles neurologiques et la douleur chronique." } }, { "@type": "Question", "name": "Le CNTF peut-il entraîner des troubles cognitifs ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles cognitifs peuvent survenir en raison de la dysfonction du CNTF." } }, { "@type": "Question", "name": "Y a-t-il un risque de dépendance aux médicaments ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains traitements peuvent entraîner une dépendance, nécessitant une surveillance." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles avec un traitement approprié." } }, { "@type": "Question", "name": "Le CNTF peut-il affecter la qualité de vie ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les troubles liés au CNTF peuvent significativement affecter la qualité de vie." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les troubles du CNTF ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des maladies auto-immunes et des traumatismes." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque pour le CNTF ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le risque de troubles liés au CNTF augmente avec l'âge." } }, { "@type": "Question", "name": "Le sexe influence-t-il le risque de troubles du CNTF ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines études montrent que le sexe peut influencer le risque de troubles." } }, { "@type": "Question", "name": "Les infections peuvent-elles augmenter le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines infections peuvent déclencher des troubles liés au CNTF." } }, { "@type": "Question", "name": "Le mode de vie influence-t-il le risque de troubles ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque." } } ] } ] }

Sources (10000 au total)

The Engage with Developmental Language Disorder (E-DLD) project: Cohort profile.

Public awareness of Developmental Language Disorder (DLD) is lower than other neurodevelopmental disorders, despite its high prevalence of 7.6%. This lower awareness means recruitment for DLD research... This paper aims to describe the families of children with DLD and adults with DLD in the database thus far.... E-DLD members sign up via our website, reporting demographic characteristics as part of this procedure. We request all E-DLD members subsequently fill in a yearly survey. The content of the yearly sur... The database currently consists of 196 parents of children with DLD and 20 individuals over the age of 16 with DLD or suspected DLD across a range of socioeconomic status (SES) backgrounds. Our initia... The findings indicate that a participant database for DLD research is feasible and useful. The rates of emotional, behavioural and sleep difficulties among the child probands are higher than reported ... What is already known on this subject Developmental Language Disorder (DLD) is characterised by expressive and/or receptive language difficulties in the absence of another biomedical condition that co...

Development and Validation of a Language Screening for Implementation in Pre-School Settings.

To prevent or mitigate long-lasting learning problems and emotional, behavioral, and social-adaption difficulties associated with language disorders, age-appropriate German language competence at scho... To develop a screening instrument to identify increased risk of LD and to evaluate its validity and feasibility within the constraints of regular universal pre-school language screening.... A two-component screening instrument including direct assessment of expressive and receptive grammar was used in a sample of 374 children with German as their dominant language attending a public pre-... The combination of the expressive and receptive grammar scales demonstrated excellent accuracy (area under the curve score 0.928). A cut-off of 18 resulted in a failing rate of 21.8% and showed good s...

Identifying Language Disorder in Bilingual Children Using Automatic Speech Recognition.

The differential diagnosis of developmental language disorder (DLD) in bilingual children represents a unique challenge due to their distributed language exposure and knowledge. The current evidence i... Eighty-four Spanish-English bilingual second graders with (... Results demonstrated moderate overall item-by-item scoring agreement (... This study provides preliminary support for the technical feasibility of ASR as a bilingual expressive language assessment tool.... https://doi.org/10.23641/asha.20249994....

Describing the Spoken Language Skills of Typically Developing Afrikaans-Speaking Children Using Language Sample Analysis: A Pilot Study.

Language sample analysis is widely regarded as the gold standard of language assessment. However, the uncertainty regarding the optimal length of sample and the limited availability of developmental l... The study involved 30 typically developing Afrikaans-speaking children aged between 3;6 and 9;6 (years;months). A descriptive research design was used to transcribe and analyze 1-hr interactions colle... Results indicated that mean length of utterance in words per minute, number of different words per minute, and total number of words per minute stabilized at 30 min and no significant differences were... The study concluded that a 30-min interaction segment provides a representative language sample for Afrikaans-speaking children who are between 3;6 and 9;6. It provides promising preliminary developme...

The impact of developmental language disorder in a defendant's description on mock jurors' perceptions and judgements.

While it has been posited that young people with language needs may be viewed more negatively (e.g., as more rude, less cooperative) than those without language needs, the impact of knowing about a pe... To examine whether the presence of a developmental language disorder (DLD) diagnosis in a defendant's information would affect mock juror ratings of guilt, sentence length, credibility and blameworthi... A total of 143 jury eligible participants read a vignette of a non-violent crime. Half of the participants (N = 73) were told the defendant has a diagnosis of DLD, while half (N = 70) were not told.... Preregistered analyses found that DLD information affected ratings of credibility and blameworthiness, though not judgements of guilt or sentence length. Unregistered content analyses were applied to ... Unlike in previous studies of the impact of autism information, information about a defendant's DLD did not affect mock jurors' likelihood of finding them guilty, or lead participants to give longer s... What is already known on the subject There is already evidence that some conditions that affect communication, specifically autism, also affect juror perceptions. Research also shows that knowing whet...

Predictors of school concern across the transition to secondary school with developmental language disorder and low language ability: A longitudinal developmental cascade analysis.

Developmental language disorder (DLD) has clear functional ramifications in the areas of social competency, emotion recognition, emotional well-being and literacy skill, which have been found to persi... To investigate the association between psychosocial domains, literacy skill and concerns about school during the transition to secondary school for adolescents with DLD, LL and their TD peers. The fir... Participants (aged 10-11 years) with DLD (n = 30), LL ((n = 29) and TD (n = 42) were recruited for this longitudinal study from eight UK primary schools. Standardized language and psychosocial assessm... Regression analyses showed pre-transition school concern to be predicted by emotion recognition for the DLD group, by social competence and emotional well-being for the LL group, and by social compete... This study concludes that transition interventions must be differentiated according to language ability; support for DLD adolescents should focus on emotion recognition skill, provision for LL adolesc... What is already known on the subject There is limited research exploring the transition from primary school to secondary for adolescents with DLD or LL ability. Research on TD has highlighted vulnerab...

Acoustic and Kinematic Methods of Indexing Spatiotemporal Stability in Children With Developmental Language Disorder.

The spatiotemporal index (STI) is a standard metric for quantifying the stability and patterning of speech movements. The STI has often been applied to individual speech articulators, but an STI deriv... A total of 85 children with DLD and with typical language development (or typically developing [TD] children), aged 4-8 years, were studied. In this methodological article, two experiments were conduc... In sentence production, most group differences aligned across kinematic and acoustic STI measures. The acoustic, but not the kinematic, STI showed higher variability in children with DLD compared with... The kinematic and acoustic STIs assess different components of speech movement patterning. However, the relationship between acoustic and kinematic spatiotemporal stability is strong in two tasks of v...

Association of Developmental Language Disorder With Comorbid Developmental Conditions Using Algorithmic Phenotyping.

Developmental language disorder (DLD) is a common (with up to 7% prevalence) yet underdiagnosed childhood disorder whose underlying biological profile and comorbidities are not fully understood, espec... To identify clinically relevant conditions that co-occur with DLD at the population level.... This case-control study used an electronic health record (EHR)-based population-level approach to compare the prevalence of comorbid health phenotypes between DLD cases and matched controls. These cas... Common and rare comorbidities of DLD at the population level were identified using EHRs and a phecode-based enrichment analysis.... Comorbidity analysis was conducted for 5273 DLD cases (mean [SD] age, 16.8 [7.2] years; 3748 males [71.1%]) and 26 353 matched controls (mean [SD] age, 14.6 [5.5] years; 18 729 males [71.1%]). Relevan... This study found both rare and common comorbidities of DLD. Comorbidity profiles may be leveraged to identify risk of additional health challenges, beyond language impairment, among children with DLD....