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"name": "Diagnostic",
"headline": "Diagnostic sur Dynamine-II",
"description": "Comment diagnostiquer une anomalie de Dynamine-II ?\nQuels tests sont utilisés pour évaluer la Dynamine-II ?\nY a-t-il des marqueurs spécifiques pour la Dynamine-II ?\nQuels symptômes peuvent indiquer un problème avec Dynamine-II ?\nLes tests génétiques sont-ils fiables pour Dynamine-II ?",
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"name": "Symptômes",
"headline": "Symptômes sur Dynamine-II",
"description": "Quels sont les symptômes d'une déficience en Dynamine-II ?\nLa Dynamine-II affecte-t-elle le système nerveux ?\nY a-t-il des signes cliniques spécifiques ?\nLes symptômes varient-ils selon l'âge ?\nPeut-on observer des symptômes respiratoires ?",
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"headline": "Prévention sur Dynamine-II",
"description": "Peut-on prévenir les anomalies de Dynamine-II ?\nLe dépistage prénatal est-il possible ?\nLes conseils génétiques sont-ils recommandés ?\nY a-t-il des facteurs environnementaux à considérer ?\nLes habitudes de vie influencent-elles la Dynamine-II ?",
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"name": "Traitements",
"headline": "Traitements sur Dynamine-II",
"description": "Quels traitements sont disponibles pour les anomalies de Dynamine-II ?\nLa thérapie génique est-elle une option ?\nLes médicaments peuvent-ils aider ?\nLa rééducation est-elle bénéfique ?\nY a-t-il des essais cliniques en cours ?",
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"headline": "Complications sur Dynamine-II",
"description": "Quelles complications peuvent survenir avec Dynamine-II ?\nLes complications sont-elles réversibles ?\nY a-t-il un risque accru de maladies associées ?\nLes complications affectent-elles la qualité de vie ?\nComment gérer les complications ?",
"url": "https://questionsmedicales.fr/mesh/D034285?mesh_terms=Prostatic+Neoplasms&page=5#section-complications"
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Dynamine-II",
"description": "Quels sont les facteurs de risque pour les anomalies de Dynamine-II ?\nL'âge joue-t-il un rôle dans les anomalies de Dynamine-II ?\nY a-t-il des prédispositions génétiques ?\nLes facteurs environnementaux influencent-ils ?\nLes habitudes de vie affectent-elles le risque ?",
"url": "https://questionsmedicales.fr/mesh/D034285?mesh_terms=Prostatic+Neoplasms&page=5#section-facteurs de risque"
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie de Dynamine-II ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses de protéines peuvent être utilisés pour diagnostiquer."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer la Dynamine-II ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent l'immunoblotting et la microscopie électronique pour visualiser les anomalies."
}
},
{
"@type": "Question",
"name": "Y a-t-il des marqueurs spécifiques pour la Dynamine-II ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de marqueurs spécifiques largement reconnus pour la Dynamine-II."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème avec Dynamine-II ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes neurologiques ou musculaires peuvent indiquer une anomalie de Dynamine-II."
}
},
{
"@type": "Question",
"name": "Les tests génétiques sont-ils fiables pour Dynamine-II ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests génétiques peuvent fournir des informations précises sur les mutations de Dynamine-II."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une déficience en Dynamine-II ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent faiblesse musculaire, troubles de la coordination et problèmes neurologiques."
}
},
{
"@type": "Question",
"name": "La Dynamine-II affecte-t-elle le système nerveux ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies de Dynamine-II peuvent entraîner des troubles neurologiques significatifs."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques spécifiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme l'atrophie musculaire et des réflexes anormaux peuvent être observés."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent varier en fonction de l'âge et de la gravité de la déficience."
}
},
{
"@type": "Question",
"name": "Peut-on observer des symptômes respiratoires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des problèmes respiratoires peuvent survenir en raison de la faiblesse musculaire."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies de Dynamine-II ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de méthodes de prévention connues pour les anomalies de Dynamine-II."
}
},
{
"@type": "Question",
"name": "Le dépistage prénatal est-il possible ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le dépistage prénatal peut être envisagé si des antécédents familiaux sont présents."
}
},
{
"@type": "Question",
"name": "Les conseils génétiques sont-ils recommandés ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les conseils génétiques peuvent aider les familles à comprendre les risques associés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux à considérer ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, les facteurs environnementaux ne sont pas clairement établis pour Dynamine-II."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie influencent-elles la Dynamine-II ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de preuves solides que les habitudes de vie influencent directement Dynamine-II."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les anomalies de Dynamine-II ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements sont principalement symptomatiques et peuvent inclure la physiothérapie."
}
},
{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche, mais n'est pas encore une option standard pour Dynamine-II."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent aider à gérer les symptômes, mais aucun n'est spécifique à Dynamine-II."
}
},
{
"@type": "Question",
"name": "La rééducation est-elle bénéfique ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la rééducation physique peut améliorer la force et la coordination chez les patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il des essais cliniques en cours ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, plusieurs essais cliniques explorent de nouvelles approches thérapeutiques pour Dynamine-II."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec Dynamine-II ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles moteurs, des problèmes respiratoires et des infections."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais beaucoup ne sont pas réversibles."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de maladies associées ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent avoir un risque accru de maladies neuromusculaires associées."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement affecter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies de Dynamine-II ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux de maladies génétiques sont un facteur de risque majeur."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans les anomalies de Dynamine-II ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge peut influencer l'apparition des symptômes, mais n'est pas un facteur de risque direct."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des mutations spécifiques dans le gène de la Dynamine-II peuvent prédisposer aux anomalies."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, l'impact des facteurs environnementaux sur Dynamine-II n'est pas bien compris."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie affectent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de preuves solides que les habitudes de vie influencent le risque de Dynamine-II."
}
}
]
}
]
}
To assess whether a diagnostic pathway in which prostate-specific membrane antigen (PSMA) positron-emission tomography (PET)/computed tomography (CT) is used as a single imaging modality is feasible t...
A total of 60 men with a prostate-specific antigen (PSA) level of 20-50 ng/mL underwent...
Lesions suspicious for PCa in the prostate gland were observed on all PSMA-PET/CTs. A total of 27/60 men (45%) already had metastatic disease on staging...
Using the PSMA-driven single imaging modality pathway in biopsy-naïve men at high-risk of PCa, a substantial number of diagnostic MRI scans could be avoided while at the same time obtaining adequate t...
Prostate-specific antigen (PSA)-based screening for prostate cancer (PCa) can reduce PCa mortality, but also involves overdetection of low-risk disease with potential adverse effects. We evaluated PCa...
The surgical treatment of men with lower urinary tract symptoms (LUTS) and significantly enlarged symptomatic prostates on active surveillance (AS) for low-risk prostate cancer (PCa) is not well defin...
Men on AS who underwent HoLEP between 2013 and 2019 were identified. Data regarding preoperative cancer workup, prostate-specific antigen (PSA), perioperative outcomes, and voiding parameters were ana...
Twenty men met the inclusion criteria. Preoperative mean max flow 7.9 ml/s, median postvoid residual 101 cc, and mean transrectal ultrasound prostate size 99 cc. Patients had a median adjusted preoper...
Men on AS for low-risk PCa can safely undergo HoLEP with significantly improved voiding parameters. Postoperative monitoring with PSA, mpMRI, and PBx can detect disease progression requiring definitiv...
Prostate-specific antigen (PSA) screening for prostate cancer is controversial but may be associated with benefit for certain high-risk groups....
To evaluate associations of county-level PSA screening prevalence with prostate cancer outcomes, as well as variation by sociodemographic and clinical factors....
This cohort study used data from cancer registries based in 8 US states on Hispanic, non-Hispanic Black, and non-Hispanic White men aged 40 to 99 years who received a diagnosis of prostate cancer betw...
County-level PSA screening prevalence was estimated using the Behavior Risk Factor Surveillance System survey data from 2004, 2006, 2008, 2010, and 2012 and weighted by population characteristics....
Multivariable logistic, Cox proportional hazards regression, and competing risks models were fit to estimate adjusted odds ratios (AOR) and adjusted hazard ratios (AHR) for associations of county-leve...
Of 814 987 men with prostate cancer, the mean (SD) age was 67.3 (9.8) years, 7.8% were Hispanic, 12.2% were non-Hispanic Black, and 80.0% were non-Hispanic White; 17.0% had advanced disease. There wer...
This population-based cohort study of men with prostate cancer suggests that higher county-level prevalence of PSA screening was associated with lower odds of advanced disease, all-cause mortality, an...
The incidence rate of prostate cancer (PCa) has continued to rise in Korea. This study aimed to construct and evaluate a 5-year PCa risk prediction model using a cohort with PSA < 10 ng/mL by incorpor...
The PCa risk prediction model including PSA levels and individual risk factors was constructed using a cohort of 69,319 participants from the Kangbuk Samsung Health Study. 201 registered PCa incidence...
The risk prediction model included age, smoking status, alcohol consumption, family history of PCa, past medical history of dyslipidemia, cholesterol levels, and PSA level. Especially, an elevated PSA...
Our risk prediction model was effective in predicting PCa in a population according to PSA levels. When PSA levels are inconclusive, an assessment of both PSA and specific individual risk factors (e.g...
Local recurrences after previous radiotherapy (RT) are increasingly being identified in biochemically recurrent prostate cancer. Salvage prostate brachytherapy (BT) is an effective and well tolerated ...
International experts in salvage prostate BT were invited (n = 34) to participate. A three-round modified Delphi technique was utilized, with questions focused on patient- and cancer-specific criteria...
Thirty international experts agreed to participate. Consensus was achieved for 56% (18/32) of statements. Consensus was achieved in several areas of patient selection: 1) A minimum of 2-3 years from i...
Areas of consensus within our Delphi study may serve as practical advice for salvage prostate BT. Future research in salvage BT should address areas of controversy identified in our study....
Thermal partial-gland ablation (TPGA) is a promising treatment option for patients with prostate cancer (PCa) that has an excellent side-effect profile. However, the literature on TPGA in high-risk PC...
We aimed to use Mendelian randomization (MR) to determine the causality between fifteen major mental disorders (MDs) and benign prostatic hyperplasia (BPH), prostate cancer (PCa), and prostatitis....
The main MR analysis was performed using the inverse variance-weighted (IVW) method....
The study found that insomnia (odds ratio [OR], 1.6190;...
Our findings provide clinicians with a basis for developing programs to prevent or treat MDs and prostatic diseases....
To evaluate the feasibility of AI-assisted reading of prostate magnetic resonance imaging (MRI) in Organized Prostate cancer Testing (OPT)....
Retrospective cohort study including 57 men with elevated prostate-specific antigen (PSA) levels ≥3 µg/L that performed bi-parametric MRI in OPT. The results of a CE-marked deep learning (DL) algorith...
The number of positive MRIs was 13 (23%), 8 (14%), and 29 (51%) for the local radiologists, expert consensus, and DL, respectively. Kappa scores were moderate for local radiologists versus expert cons...
The Dl-algorithm showed low agreement with both local and expert radiologists. Training and validation of DL-algorithms in specific screening cohorts is essential before introduction in organized test...
Numerous human pathologies, such as neoplasia, are related to particular bacteria and changes in microbiome constituents. To investigate the association between an imbalance of bacteria and prostate c...
