Quelles complications peuvent survenir avec des troubles du transport des ARN ?
Des complications incluent des troubles métaboliques, neurologiques et de croissance.
ComplicationsTroubles métaboliquesCroissance
#2
Les troubles du transport des ARN peuvent-ils entraîner des maladies chroniques ?
Oui, ils peuvent contribuer à des maladies chroniques comme des troubles neurologiques.
Maladies chroniquesTroubles neurologiquesARN
#3
Y a-t-il des risques de cancer associés aux troubles du transport des ARN ?
Certaines anomalies dans le transport des ARN peuvent augmenter le risque de cancer.
CancerAnomaliesARN
#4
Les complications peuvent-elles affecter la qualité de vie ?
Oui, les complications liées aux troubles du transport des ARN peuvent gravement affecter la qualité de vie.
Qualité de vieComplicationsARN
#5
Comment les complications sont-elles gérées dans ces troubles ?
La gestion implique des soins multidisciplinaires pour traiter les symptômes et complications.
GestionSoins multidisciplinairesSymptômes
Facteurs de risque
5
#1
Quels sont les facteurs de risque pour les troubles du transport des ARN ?
Les facteurs incluent des mutations génétiques, des infections virales et des carences nutritionnelles.
Facteurs de risqueMutations génétiquesInfections virales
#2
L'hérédité joue-t-elle un rôle dans les troubles du transport des ARN ?
Oui, de nombreux troubles sont héréditaires et peuvent être transmis par les parents.
HéréditéTroublesARN
#3
Les infections peuvent-elles affecter le transport des ARN ?
Certaines infections virales peuvent perturber le transport et la fonction des ARN.
InfectionsViralesTransport des ARN
#4
Les carences nutritionnelles sont-elles un facteur de risque ?
Oui, des carences en vitamines et minéraux peuvent affecter le transport des ARN.
Carences nutritionnellesVitaminesMinéraux
#5
Le stress environnemental influence-t-il le transport des ARN ?
Oui, le stress environnemental peut affecter l'expression des gènes et le transport des ARN.
Stress environnementalExpression des gènesTransport des ARN
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"text": "Oui, ils peuvent aider les familles à comprendre les risques et les options disponibles."
}
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"position": 16,
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"text": "Les traitements peuvent inclure des thérapies géniques et des médicaments ciblés."
}
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"position": 18,
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}
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}
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"position": 20,
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"text": "Oui, elles peuvent améliorer la fonction musculaire et neurologique affectée par ces troubles."
}
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"name": "Quelles complications peuvent survenir avec des troubles du transport des ARN ?",
"position": 21,
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}
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"position": 22,
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}
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"@type": "Question",
"name": "Y a-t-il des risques de cancer associés aux troubles du transport des ARN ?",
"position": 23,
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"text": "Certaines anomalies dans le transport des ARN peuvent augmenter le risque de cancer."
}
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"position": 24,
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}
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"position": 26,
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}
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"position": 27,
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"position": 28,
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"text": "Certaines infections virales peuvent perturber le transport et la fonction des ARN."
}
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"@type": "Question",
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"position": 29,
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}
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The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Department of Psychiatry, University of Melbourne, Parkville, VIC, Australia. Electronic address: ken.pang@mcri.edu.au.
The current implementation of Pathogen Reduction Technologies (PRTs) offers advantages and disadvantages to transfusion medicine. PRT rollout may significantly reduce the incidence of transfusion-tran...
It remains unclear whether the association between balanced blood component transfusion and lower mortality is generalizable to trauma patients receiving varying transfusion volumes. We sought to stud...
Adult patients in the 2013 to 2018 American College of Surgeons Trauma Quality Improvement Program database receiving ≥6 red blood cell, ≥1 platelet, and ≥1 fresh frozen plasma within 4 hours were inc...
A total of 14,549 patients were included. In patients receiving 6 to 10 units of red blood cells, red blood cell:platelet ratios were not associated with 4-hour mortality, and only red blood cell:fres...
The association between balanced blood component transfusion and 4-hour mortality is not homogenous in trauma patients requiring different transfusion volumes and is specifically less evident in patie...
to investigate the influence of the leukoreduction moment (preor post-storage) of blood components on the clinical outcomes of patients transfused in the emergency department....
retrospective cohort study of patients aged 18 years or older who received preor post-storage leukoreduced red blood cell or platelet concentrate in the emergency department and remained in the instit...
in a sample of 373 patients (63.27% male, mean age 54.83) and 643 transfusions (69.98% red blood cell), it was identified that the leukoreduction moment influenced the length of hospital stay (p<0.009...
patients who received pre-storage leukoreduced blood components in the emergency department had a shorter length of hospital stay....
Blood component resuscitation is associated with hypocalcemia (HC) (iCal <0.9 mmol/L) that contributes to coagulopathy and death in trauma patients. It is unknown whether or not whole blood (WB) resus...
This is a retrospective review of all adult trauma patients who received WB from July 2018 to December 2020. Variables included transfusions, ionized calcium levels, and calcium replacement. Patients ...
Two hundred twenty-three patients received WB and met the inclusion criteria. 107 (48%) received WB only. HC occurred in 13% of patients who received more than one WB unit compared to 29% of WB and ot...
HC and failure to correct HC are significant risk factors for mortality in trauma. Resuscitations with WB only and WB in combination with other blood components are associated with HC especially when ...
Blood component transfusion is a common intervention in the neonatal intensive care unit (NICU). Parents consent on their babies' behalf. This study aimed to explore parents' understandings and experi...
A "low inference" qualitative descriptive semi-structured interview approach was utilised. Grounded theory was employed. Parents described their memories of babies' transfusions, their responses to th...
A purposive sample of 17 parents whose babies required blood transfusion in the NICU participated. Parents talked about their initial fears of transfusion, later replaced by confidence in the process ...
Parents in our study trust information from the healthcare professionals caring for their baby and would like more specific information about how blood transfusion will impact their baby, in a variety...
The transfusion of blood products is a life-saving clinical practice in patients with bleeding, hemoglobinopathy, and cancer. It was aimed herein to analyze the frequency and types of blood component-...
This retrospective study was conducted at a tertiary care academic pediatric hospital....
During the study period, 30,811 transfusions were administered to 25,448 patients. There were 103 ATRs detected in 81 patients (0.33%; 3.34 reactions per 1000 transfusions, mean age 8.3 ± 5.98 years, ...
Within our hospital, pediatric hematology-oncology wards and the stem cell transplantation unit had the most frequent ATR reports; therefore, when transfusions are carried out, increased attention sho...
With the emergence of whole blood (WB) in trauma resuscitation, cost-related comparisons are of significant importance to providers, blood banks, and hospital systems throughout the country. The objec...
A retrospective review of adult and pediatric trauma patients who received either LTO+WB or CT from time of injury to within 4 hours of arrival was performed. Annual mean cost per unit of blood produc...
Prehospital LTO+WB transfusion began at this institution in January 2018. After the initiation of the WB transfusion, the mean annual cost decreased 17.3% for all blood products, and the average net d...
With increased use of LTO+WB for resuscitation, cost comparison is of significant importance to all stakeholders. Low titer O+ WB was associated with reduced cost in severely injured patients. Ongoing...
Therapeutic/Care Management; Level IV....
Although it remains controversial, premedication before transfusion is a common clinical practice to prevent transfusion-associated adverse reactions (TAARs) in Taiwan. Thus, we aimed to investigate w...
Clinical data from outpatients receiving transfusion therapy, including predisposing diseases, histories of transfusion and TAARs, premedication and the occurrence of TAARs in the period April 2017 to...
A total of 5018 blood units were transfused to 803 outpatients, with 2493 transfusion events reported in the study interval. The most frequently transfused component was leukocyte-reduced packed red c...
Decreased premedication was not associated with increased incidence of TAARs in outpatients; these findings provide important evidence to support the need to revise clinical practices in the era of le...
To determine the existence of guidelines regarding the appropriate clinical use of blood and blood components, transfusion requests, and blood issuing/reception documents and procedures. The different...
This systematic review and meta-analysis was conducted to compare outcomes, including transfusion volume, complications, intensive care unit length of stay, and mortality for adult civilian trauma pat...
A systematic review and meta-analysis were conducted using studies that evaluated outcomes of transfusion of WB, COMP, or WB + COMP for adult civilian trauma patients. A search of PubMed, Embase, and ...
This study identified an increased risk of 24-h mortality with COMP versus WB + COMP (relative risk: 1.40 [1.10, 1.78]) and increased transfusion volumes of red blood cells with COMP versus WB at 6 an...
Transfusion with WB + COMP is associated with lower 24-h mortality versus COMP and transfusion with WB is associated with a lower volume of red blood cells transfused at both 6 and 24 h. Based on thes...
