questionsmedicales.fr
Maladies du système immunitaire
Troubles de l'activation mastocytaire
Mastocytose
Mastocytose cutanée
Mastocytose cutanée : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Mastocytose
Biopsie cutanée
Urticaire
Affections cutanées
Antécédents médicaux
Allergies
Symptômes
5
Démangeaisons
Lésions cutanées
Variabilité des symptômes
Individus
Symptômes systémiques
Nausées
Lésions cutanées
Contagiosité
Prévention
5
Stress
Poussées de symptômes
Soins de la peau
Irritations
Traitements
5
Antihistaminiques
Corticostéroïdes
Antihistaminiques
Démangeaisons
Photothérapie
Lésions cutanées
Gestion des symptômes
Traitements
Traitements alternatifs
Efficacité
Complications
5
Complications
Infections cutanées
Mastocytose systémique
Évolution
Gestion
Consultation spécialisée
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Maladies auto-immunes
Risque
Produits chimiques
Exposition
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"name": "Comment diagnostique-t-on la mastocytose cutanée ?",
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"text": "Le diagnostic repose sur l'examen clinique et la biopsie cutanée pour détecter les mastocytes."
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},
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"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer la mastocytose ?",
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"name": "Quels sont les symptômes courants de la mastocytose cutanée ?",
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"@type": "Question",
"name": "La mastocytose cutanée provoque-t-elle des douleurs ?",
"position": 7,
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}
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"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, l'intensité et la nature des symptômes peuvent varier considérablement."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes systémiques associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes systémiques comme des nausées peuvent survenir dans certains cas."
}
},
{
"@type": "Question",
"name": "Les lésions cutanées sont-elles contagieuses ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les lésions cutanées de la mastocytose ne sont pas contagieuses."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la mastocytose cutanée ?",
"position": 11,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Les allergènes peuvent-ils aggraver la condition ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, l'exposition à certains allergènes peut aggraver les symptômes."
}
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{
"@type": "Question",
"name": "Faut-il éviter certains médicaments ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent déclencher des réactions chez les patients sensibles."
}
},
{
"@type": "Question",
"name": "L'évitement du stress aide-t-il ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Gérer le stress peut aider à réduire les poussées de symptômes chez certains patients."
}
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{
"@type": "Question",
"name": "Les soins de la peau sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, des soins appropriés de la peau peuvent aider à minimiser les irritations."
}
},
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"@type": "Question",
"name": "Quels traitements sont disponibles pour la mastocytose cutanée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des antihistaminiques et des corticostéroïdes topiques."
}
},
{
"@type": "Question",
"name": "Les antihistaminiques sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils aident à réduire les démangeaisons et les rougeurs."
}
},
{
"@type": "Question",
"name": "La photothérapie est-elle une option de traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la photothérapie peut être utilisée pour traiter les lésions cutanées."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils permanents ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les traitements visent à gérer les symptômes, pas à guérir la maladie."
}
},
{
"@type": "Question",
"name": "Des traitements alternatifs existent-ils ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines personnes explorent des traitements alternatifs, mais leur efficacité n'est pas prouvée."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec la mastocytose cutanée ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des infections cutanées peuvent survenir en raison de lésions."
}
},
{
"@type": "Question",
"name": "La mastocytose cutanée peut-elle évoluer vers une forme plus grave ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans de rares cas, elle peut évoluer vers une mastocytose systémique."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications ne sont pas fréquentes mais peuvent survenir chez certains patients."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite souvent une consultation spécialisée."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent affecter la qualité de vie en raison de l'inconfort."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de la mastocytose cutanée ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux et des allergies cutanées."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans la mastocytose cutanée ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la mastocytose cutanée est plus fréquente chez les enfants et les jeunes adultes."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus touchées que les hommes ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, la mastocytose cutanée affecte les hommes et les femmes de manière égale."
}
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{
"@type": "Question",
"name": "Les maladies auto-immunes augmentent-elles le risque ?",
"position": 29,
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"text": "Oui, certaines maladies auto-immunes peuvent augmenter le risque de mastocytose."
}
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"@type": "Question",
"name": "L'exposition à des produits chimiques est-elle un facteur ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certains produits chimiques peut être un facteur de risque."
}
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/01/2025
Contenu vérifié selon les dernières recommandations médicales
9 publications dans cette catégorie
Affiliations :
Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
6 publications dans cette catégorie
Affiliations :
Allergologische Poliklinik, Klinik für Dermatologie, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz. karin.hartmann@usb.ch.
5 publications dans cette catégorie
Affiliations :
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, 80802 Munich, Germany.
Department of Dermatology and Allergy Centre, Odense University Hospital, 5000 Odense, Denmark.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Department of Hematology and Mastocytosis Expert Centre (CEREMAST), Necker Children's Hospital and Paris Descartes University, Assistance Publique Hôpitaux de Paris, Paris, France. Electronic address: ohermine@gmail.com.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Department of Allergology, Medical University of Gdansk, Gdansk, Poland.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Section of Hematology, Department of Medicine, Verona University Hospital, Verona, Italy.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Allergy Unit, Verona University Hospital, Verona, Italy.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Publications dans "Mastocytose cutanée" :
5 publications dans cette catégorie
Affiliations :
Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria; Internal Medicine Small Animals, University Clinic for Small Animals, Department/University Clinic for Companion Animals and Horses, University of Veterinary Medicine, Vienna, Austria.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Pediatric Dermatology Unit, Department of Medicine, University of Padova, Padova, Italy.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Pediatric Dermatology Unit, Department of Medicine, University of Padova, Padova, Italy.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
University Hospital and Faculty of Medicine, Brno, Czechia.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Faculty of Medicine and Health Sciences, Department of Immunology-Allergology-Rheumatology, University of Antwerp and Antwerp University Hospital, Antwerpen, Belgium.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Publications dans "Mastocytose cutanée" :
4 publications dans cette catégorie
Affiliations :
Department of Oncology, Haematology, Haemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology, Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Publications dans "Mastocytose cutanée" :
To review the safety and efficacy of anti-immunoglobulin E (IgE) monotherapy or as an adjunct to oral immunotherapy (OIT) in the treatment of IgE-mediated food allergy....
Literature searches were performed using the Excerpta Medica dataBASE, Medline, Scopus, and PubMed Central to identify articles in English related to food allergy and anti-IgE therapies, including oma...
Original research articles reviewed include interventional studies, retrospective and prospective observational studies, peer-reviewed reviews, and systematic reviews. Data were reviewed and summarize...
Here, we discuss the current anti-IgE therapies being studied as a potential treatment option for food allergy. We also review trial design, safety, and efficacy data on the use of anti-IgE therapies ...
Over the past 20 years, substantial progress has been made in understanding the potential role of anti-IgE therapies for food allergy. Anti-IgE therapies seem to be a promising option that may increas...
The mechanism of omalizumab in urticaria is not literally known. Omalizumab may affect receptors on the mast cell surface in other ways, especially other than Fc epsilon RI....
Thirty patients who were treated with omalizumab with the diagnosis of chronic urticaria were included in the study. For serum vasoactive intestinal peptide (VIP), kallikrein (KAL), and substance p (S...
While SP, KAL, and VIP values increased continuously, it was observed that the D-dimer value decreased....
This study shows that omalizumab can affect mast cells other than IgE. To the best of our knowledge, this is the first study to show the relationship between omalizumab and VIP....
The purpose of this review is to identify recent advances in our understanding and management of immunoglobulin E (IgE)-mediated antibiotic allergy....
Antibiotics remain a leading cause of fatal anaphylaxis reported to the FDA. However, recent advances have defined the features of adult and pediatric patients without true IgE-mediated allergy or any...
Recent advances in defining true IgE-mediated drug allergy have helped to identify patients unlikely to be skin-test positive. In turn, this has identified patients who can skip skin testing and proce...
Detection of allergen-specific immunoglobulin E (IgE) antibodies (Abs) in serum would allow for screening of the causative allergen in patients with type-I allergy. In this study, we developed a new a...
To review the characteristic clinical and laboratory features of inborn errors of immunity (IEI) that are associated with elevated immunoglobulin (Ig)E levels....
Primary peer-reviewed literature....
Original research articles reviewed include interventional studies, retrospective studies, case-control studies, cohort studies, and review articles related to the subject matter....
An extensive literature review was completed to allow for comprehensive evaluation of several monogenic IEI. This review includes a description of the classic clinical features, common infections, cha...
IEI should be considered in patients with elevated IgE levels, especially if they have recurrent infections, eczematous dermatitis, malignancy, lymphoproliferation, autoimmunity, or connective tissue ...
In the airway, IgE is traditionally regarded as a key mediator in allergic diseases, such as AR and allergic asthma. However, growing evidence demonstrates the importance of local IgE in airway inflam...
Our study aimed to investigate whether serum total IgE and blood eosinophils were associated with radiological features of bronchiectasis in a Chinese cohort....
We retrospectively enrolled bronchiectasis patients who visited Peking University Third Hospital from Jan 1...
A total of 125 bronchiectasis patients were enrolled, with 50.4% (63/125) female, and a mean age of 62.4 ± 14.1 years. The median serum total IgE level and blood eosinophil count were 47.7 (19.8, 123....
Our study demonstrated that serum total IgE and the blood eosinophil count were associated with the radiological extent and severity of bronchiectasis, necessitating further investigation on the role ...
Laboratory biomarkers to estimate the severity of coronavirus disease 2019 (COVID-19) are crucial during the pandemic since resource allocation must be carefully planned....
To evaluate the effects of basal serum total immunoglobulin E (IgE) levels and changes in inflammatory parameters on the clinical progression of patients hospitalised with COVID-19....
Patients hospitalised with confirmed COVID-19 were included in the study. Laboratory data and total IgE levels were measured on admission. Lymphocyte, eosinophil, ferritin, d-dimer and C-reactive prot...
The study enrolled 202 patients, of which 102 (50.5%) were males. The average age was 50.17 ± 19.68 years. Of the COVID-19 patients, 41 (20.3%) showed clinical progression. Serum total IgE concentrati...
Our single-centre pilot study determined that total IgE levels may be a negative prognostic factor for clinical progression in patients hospitalised due to COVID-19 infection. Future studies are requi...
Autoimmune diseases have a prevalence of approximately 7 to 9% and are classified as either organ-specific diseases, including type I diabetes, multiple sclerosis, inflammatory bowel disease and myast...
Prothrombotic and pro-inflammatory states are known cerebral venous thrombosis risk factors. To date, two cases of venous thrombotic events after immunoglobulin-E mediated anaphylaxis have been report...
A 51-year-old female presented with headache, language, and mental disturbance lasting for two days. Two days before the onset, she had undergone a provocative test with deflazacort to study an allerg...
The close temporal association between the anaphylactic reaction and cerebral venous thrombosis suggests that anaphylactic reaction could have been a cerebral venous thrombosis precipitating factor. I...