Titre : Groupes témoins

Groupes témoins : Questions médicales fréquentes

Termes MeSH sélectionnés :

Disability Evaluation

Questions fréquentes et termes MeSH associés

Diagnostic 4

#1

Comment identifier un groupe témoin ?

Un groupe témoin est constitué de participants similaires au groupe traité, mais sans intervention.
Groupes témoins Méthodes de recherche
#2

Quel est le rôle d'un groupe témoin ?

Il permet d'évaluer l'effet d'un traitement en comparant les résultats avec ceux du groupe traité.
Groupes témoins Évaluation des traitements
#3

Comment choisir un groupe témoin ?

Le choix doit se baser sur des critères d'inclusion similaires à ceux du groupe traité.
Groupes témoins Critères d'inclusion
#4

Les groupes témoins sont-ils toujours nécessaires ?

Oui, ils sont essentiels pour établir des comparaisons valides dans les études cliniques.
Groupes témoins Essais cliniques

Symptômes 2

#1

Les groupes témoins montrent-ils des symptômes ?

Non, ils ne reçoivent pas de traitement, donc ils ne présentent pas de symptômes liés au traitement.
Groupes témoins Symptômes
#2

Comment les symptômes sont-ils évalués ?

Les symptômes sont évalués par des questionnaires ou des examens cliniques dans les deux groupes.
Évaluation des symptômes Groupes témoins

Prévention 2

#1

Les groupes témoins aident-ils à la prévention ?

Oui, ils permettent d'évaluer l'efficacité des interventions préventives par comparaison.
Prévention Groupes témoins
#2

Comment les groupes témoins influencent-ils la prévention ?

Ils fournissent des données sur l'impact des mesures préventives en comparaison avec l'absence d'intervention.
Mesures préventives Groupes témoins

Traitements 2

#1

Quel type de traitement est comparé ?

Le traitement expérimental est comparé à un placebo ou à un traitement standard dans le groupe témoin.
Traitements expérimentaux Groupes témoins
#2

Comment les résultats sont-ils mesurés ?

Les résultats sont mesurés par des critères prédéfinis, comme l'amélioration des symptômes.
Mesure des résultats Groupes témoins

Complications 2

#1

Les complications sont-elles observées dans les groupes témoins ?

Les complications peuvent être observées, mais elles ne sont pas dues au traitement expérimental.
Complications Groupes témoins
#2

Comment les complications sont-elles analysées ?

Elles sont analysées en comparant leur fréquence entre le groupe témoin et le groupe traité.
Analyse des complications Groupes témoins

Facteurs de risque 2

#1

Les groupes témoins aident-ils à identifier des facteurs de risque ?

Oui, ils permettent de comparer les facteurs de risque entre les groupes traité et témoin.
Facteurs de risque Groupes témoins
#2

Comment les facteurs de risque sont-ils évalués ?

Ils sont évalués par des questionnaires et des analyses statistiques dans les deux groupes.
Évaluation des facteurs de risque Groupes témoins
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 21/04/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Thomas Steger-Hartmann

5 publications dans cette catégorie

Affiliations :
  • Bayer Research & Development, Pharmaceuticals, Investigative Toxicology, Berlin, Germany.

Tania Rivera-Hernandez

2 publications dans cette catégorie

Affiliations :
  • School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, Queensland, Australia.
Publications dans "Groupes témoins" :

Mark J Walker

2 publications dans cette catégorie

Affiliations :
  • School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, Queensland, Australia.
Publications dans "Groupes témoins" :

Mark R Davies

2 publications dans cette catégorie

Affiliations :
  • Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Publications dans "Groupes témoins" :

Alexander Gurjanov

2 publications dans cette catégorie

Affiliations :
  • Bayer Research & Development, Pharmaceuticals, Investigative Toxicology, Berlin, Germany. Electronic address: alexander.gurjanov@bayer.com.

Lea A I Vaas

2 publications dans cette catégorie

Affiliations :
  • Bayer Research & Development, Pharmaceuticals, Research & Pre-Clinical Statistics Group, Berlin, Germany.

Matthew Clark

2 publications dans cette catégorie

Affiliations :
  • KALOS Technologies, Philadelphia, Pennsylvania, USA.

Alexander Amberg

2 publications dans cette catégorie

Affiliations :
  • Sanofi, Preclinical Safety, Frankfurt, Germany.

Frank Bringezu

2 publications dans cette catégorie

Affiliations :
  • Merck Healthcare KGaA, Chemical & Preclinical Safety, Darmstadt, Germany.

Wolfgang Muster

2 publications dans cette catégorie

Affiliations :
  • Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center, Basel, Switzerland.

Brice Batomen

1 publication dans cette catégorie

Affiliations :
  • Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Publications dans "Groupes témoins" :

Tarik Benmarhnia

1 publication dans cette catégorie

Affiliations :
  • Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.
  • Irset Institut de Recherche en Santé, Environnement et Travail, Inserm, University of Rennes, EHESP, Rennes, France.
Publications dans "Groupes témoins" :

Hua Li

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Lumei Huang

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Hailong Jiang

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Jianyang Fang

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Zhide Guo

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Fei Gao

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Mei Chen

1 publication dans cette catégorie

Affiliations :
  • College of Materials Science and Engineering, Hunan University Changsha Hunan 410082 China.
Publications dans "Groupes témoins" :

Duo Xu

1 publication dans cette catégorie

Affiliations :
  • Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University Xiamen Fujian 361102 China zhangxzh@xmu.edu.cn zijing.li@xmu.edu.cn.
Publications dans "Groupes témoins" :

Sources (10000 au total)

Psychometric evaluation of the WHODAS 2.0 and prevalence of disability in a Swedish general population.

The World Health Organization Disability Assessment Schedule (WHODAS 2.0) is a generic questionnaire that captures health and disability-related functioning information corresponding to six major life... A cross-sectional survey was performed. Internal consistency reliability was assessed with Cronbach's alpha. The construct validity was evaluated with item-total correlation, Pearson's correlation bet... Three thousand four hundred and eighty two adults aged 19-103 years (response rate 43%) participated. Significantly higher degrees of disability were reported by the oldest age group (≥ 80 years), adu... The psychometric properties of the self-administered Swedish 36-item version of the WHODAS 2.0 are comparable to those of other language versions of the instrument. Data of the prevalence of disabilit...

Health disparities associated with access to disability evaluations for toddlers in Early Head Start.

The aim of this investigation was to examine developmental, sociodemographic and familial factors associated with parent reported access to an evaluation in an Early Head Start sample. Children with d... This study (n = 191) examined how developmental, sociodemographic and parent factors at age 2 were associated with parent reporting the child being evaluated by age 3. Two logistic regression analyses... The first model found that children in the monitoring zone of developmental risk were more likely to be evaluated per parent report if they were born preterm, male, with increased behaviour problems, ... This study highlights barriers associated with access to developmental and disability evaluations for children in at-risk families. Health disparities are negatively associated with children's access ...

Health professionals' experiences with the PEDI-UG: What do Ugandan occupational therapists say about the utility and value of the Pediatric Evaluation of Disability Inventory (PEDI-UG) for children with disabilities?

The Uganda version of Pediatric Evaluation of Disability Inventory (PEDI-UG) was culturally adapted and validated from the PEDI-US, a tool used to evaluate the functional capability of children with o... A qualitative research design was chosen to explore the participants' viewpoints concerning the utility and value of the PEDI-UG for children with disabilities. Purposive sampling was used to recruit ... Several challenges concerning the contextual use of PEDI-UG were reported. For example, PEDI-UG being culturally adapted in two languages (English and Luganda) makes it difficult for health profession... The findings of this study suggest that health professionals are challenged with the use of the PEDI-UG assessment in diverse cultural contexts and/or languages. These challenges are important conside...

Confirmed disability progression as a marker of permanent disability in multiple sclerosis.

The prevention of disability over the long term is the main treatment goal in multiple sclerosis (MS); however, randomized clinical trials evaluate only short-term treatment effects on disability. Thi... In total, 14,802 6-month confirmed disability progression events were identified in 8741 patients from the global MSBase registry. For each 6-month confirmed progression event (13,321 in the developme... The score was based on age, sex, MS phenotype, relapse activity, disability score and its change from baseline, number of affected functional system domains and worsening in six of the domains. In the... Clinicodemographic characteristics of 6-month confirmed disability progression events identify those at high risk of sustained long-term disability. This knowledge will allow future trials to better a...

The impact of resilience on headache disability as measured by the Migraine Disability Assessment (MIDAS).

Our objectives were to examine cross-sectional correlations of headache disability with measures of resilience, anxiety, and depression, and to determine if resilience modified the association between... Resilience is associated with quality of life and functioning among patients with chronic conditions. We investigated whether resilience strongly mitigates headache-related disability as measured by t... We prospectively recruited 160 patients with primary headache disorders seen in a tertiary headache medicine program between February 20, 2018 and August 2, 2019. Each participant completed the MIDAS,... The CDRS-25 score was negatively correlated with the total MIDAS (r = -0.21, p = 0.009), GAD-7 (r = -0.56, p < 0.001), and PHQ-9 scores (r = -0.34, p < 0.001). Well-being inversely correlated with dis... Traits associated with resilience decreased the odds of severe disability from headaches, whereas anxiety, depression, and headache frequency were strongly associated with higher disability from heada...

Clinically meaningful change: evaluation of the Rasch-built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS) and the ALSFRS-R.

To investigate clinically meaningful change for ROADS and ALSFRS-R using a patient-defined approach.... Data were reviewed from participants assessed at the Emory ALS Center from 2019-2022 with two assessments using both ROADS and ALSFRS-R and a completed patient-reported global impression of change sca... Data were included from 162 participants. For ROADS (total possible normed score = 146), MID = 5.81 and MDC = 2.83 points. For ALSFRS-R (total possible sum-score = 48), MID = 3.24 and MDC = 1.59 point... Changes that are on average less than 5.81 points (3.98%) on the normed ROADS score or less than 3.24 points (6.75%) on the ALSFRS-R sum-score may not be clinically meaningful according to a patient-d...

Community-based outpatient rehabilitation for the treatment of breast cancer-related upper extremity disability: an evaluation of practice-based evidence.

To evaluate the impact and acceptability of outpatient physical or occupational therapy (PT/OT) for breast cancer survivors (BCS) with varying levels of upper extremity disability (UED).... We retrospectively extracted patient and therapy characteristics, UED measured by quick-disabilities of the arm, shoulder and hand (QuickDASH, 0-100 pts.), and patient-rated acceptability (1-item, 0-1... Patients (N = 417) were 59.89 ± 12.06 years old, 99% female, and attended approximately 10 PT/OT sessions (IQR = 6.0-16.0). Most had high baseline UED (62%), followed by moderate (25%) or low UED (13%... Outpatient cancer rehabilitation is associated with significant improvement in UED for BCS and was acceptable to patients regardless of UED severity at baseline....

Adaption and psychometric evaluation of the Hindi version of Neck Disability Index in the rural population of Northern India: A cross cultural study.

To ensure the validity and therapeutic utility of the Neck disability index (NDI) scale, translations, cultural adaptations and psychometric evidence is necessary. This study aimed to address the abse... Following guidelines provided by the American Association of Orthopedic Surgeons, the original English NDI scale was cross-culturally adapted into Hindi. The adaptation process included translations (... The NDI-Hi version exhibited favorable psychometric properties, including good test-retest reliability with an intra-class correlation coefficient (ICC) of 0.87. Internal consistency of the scale was ... The NDI-Hi demonstrated validity and reliability as an outcome tool for assessing neck disability. It can be effectively utilized in clinical practice and research settings involving Hindi-speaking in...