Titre : Groupes témoins

Groupes témoins : Questions médicales fréquentes

Termes MeSH sélectionnés :

Molecular Docking Simulation
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Groupes témoins : Questions médicales les plus fréquentes", "headline": "Groupes témoins : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Groupes témoins : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-25", "dateModified": "2025-04-21", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Groupes témoins" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Méthodes", "url": "https://questionsmedicales.fr/mesh/D008722", "about": { "@type": "MedicalCondition", "name": "Méthodes", "code": { "@type": "MedicalCode", "code": "D008722", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "E05.581" } } }, "about": { "@type": "MedicalCondition", "name": "Groupes témoins", "alternateName": "Control Groups", "code": { "@type": "MedicalCode", "code": "D035061", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Thomas Steger-Hartmann", "url": "https://questionsmedicales.fr/author/Thomas%20Steger-Hartmann", "affiliation": { "@type": "Organization", "name": "Bayer Research & Development, Pharmaceuticals, Investigative Toxicology, Berlin, Germany." } }, { "@type": "Person", "name": "Tania Rivera-Hernandez", "url": "https://questionsmedicales.fr/author/Tania%20Rivera-Hernandez", "affiliation": { "@type": "Organization", "name": "School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, Queensland, Australia." } }, { "@type": "Person", "name": "Mark J Walker", "url": "https://questionsmedicales.fr/author/Mark%20J%20Walker", "affiliation": { "@type": "Organization", "name": "School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, Queensland, Australia." } }, { "@type": "Person", "name": "Mark R Davies", "url": "https://questionsmedicales.fr/author/Mark%20R%20Davies", "affiliation": { "@type": "Organization", "name": "Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia." } }, { "@type": "Person", "name": "Alexander Gurjanov", "url": "https://questionsmedicales.fr/author/Alexander%20Gurjanov", "affiliation": { "@type": "Organization", "name": "Bayer Research & Development, Pharmaceuticals, Investigative Toxicology, Berlin, Germany. Electronic address: alexander.gurjanov@bayer.com." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Molecular docking, simulation and binding free energy analysis of small molecules as PfHT1 inhibitors.", "datePublished": "2022-08-26", "url": "https://questionsmedicales.fr/article/36026508", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1371/journal.pone.0268269" } }, { "@type": "ScholarlyArticle", "name": "Py-CoMFA, docking, and molecular dynamics simulations of Leishmania (L.) amazonensis arginase inhibitors.", "datePublished": "2024-05-21", "url": "https://questionsmedicales.fr/article/38773273", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1038/s41598-024-62520-2" } }, { "@type": "ScholarlyArticle", "name": "Exploring the molecular mechanism of ginseng against anthracycline-induced cardiotoxicity based on network pharmacology, molecular docking and molecular dynamics simulation.", "datePublished": "2024-09-06", "url": "https://questionsmedicales.fr/article/39243097", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1186/s41065-024-00334-y" } }, { "@type": "ScholarlyArticle", "name": "Study of the antidiabetic mechanism of berberine compound on FOXO1 transcription factor through molecular docking and molecular dynamics simulations.", "datePublished": "2024-07-09", "url": "https://questionsmedicales.fr/article/38981921", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s00894-024-06060-6" } }, { "@type": "ScholarlyArticle", "name": "Research advances of molecular docking and molecular dynamic simulation in recognizing interaction between muscle proteins and exogenous additives.", "datePublished": "2023-07-08", "url": "https://questionsmedicales.fr/article/37453331", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.foodchem.2023.136836" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Techniques d'investigation", "item": "https://questionsmedicales.fr/mesh/D008919" }, { "@type": "ListItem", "position": 3, "name": "Méthodes", "item": "https://questionsmedicales.fr/mesh/D008722" }, { "@type": "ListItem", "position": 4, "name": "Groupes témoins", "item": "https://questionsmedicales.fr/mesh/D035061" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Groupes témoins - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Groupes témoins", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-09", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Groupes témoins", "description": "Comment identifier un groupe témoin ?\nQuel est le rôle d'un groupe témoin ?\nComment choisir un groupe témoin ?\nLes groupes témoins sont-ils toujours nécessaires ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Groupes témoins", "description": "Les groupes témoins montrent-ils des symptômes ?\nComment les symptômes sont-ils évalués ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Groupes témoins", "description": "Les groupes témoins aident-ils à la prévention ?\nComment les groupes témoins influencent-ils la prévention ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Groupes témoins", "description": "Quel type de traitement est comparé ?\nComment les résultats sont-ils mesurés ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Groupes témoins", "description": "Les complications sont-elles observées dans les groupes témoins ?\nComment les complications sont-elles analysées ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Groupes témoins", "description": "Les groupes témoins aident-ils à identifier des facteurs de risque ?\nComment les facteurs de risque sont-ils évalués ?", "url": "https://questionsmedicales.fr/mesh/D035061?mesh_terms=Molecular+Docking+Simulation&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment identifier un groupe témoin ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un groupe témoin est constitué de participants similaires au groupe traité, mais sans intervention." } }, { "@type": "Question", "name": "Quel est le rôle d'un groupe témoin ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Il permet d'évaluer l'effet d'un traitement en comparant les résultats avec ceux du groupe traité." } }, { "@type": "Question", "name": "Comment choisir un groupe témoin ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Le choix doit se baser sur des critères d'inclusion similaires à ceux du groupe traité." } }, { "@type": "Question", "name": "Les groupes témoins sont-ils toujours nécessaires ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils sont essentiels pour établir des comparaisons valides dans les études cliniques." } }, { "@type": "Question", "name": "Les groupes témoins montrent-ils des symptômes ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Non, ils ne reçoivent pas de traitement, donc ils ne présentent pas de symptômes liés au traitement." } }, { "@type": "Question", "name": "Comment les symptômes sont-ils évalués ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes sont évalués par des questionnaires ou des examens cliniques dans les deux groupes." } }, { "@type": "Question", "name": "Les groupes témoins aident-ils à la prévention ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils permettent d'évaluer l'efficacité des interventions préventives par comparaison." } }, { "@type": "Question", "name": "Comment les groupes témoins influencent-ils la prévention ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Ils fournissent des données sur l'impact des mesures préventives en comparaison avec l'absence d'intervention." } }, { "@type": "Question", "name": "Quel type de traitement est comparé ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement expérimental est comparé à un placebo ou à un traitement standard dans le groupe témoin." } }, { "@type": "Question", "name": "Comment les résultats sont-ils mesurés ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les résultats sont mesurés par des critères prédéfinis, comme l'amélioration des symptômes." } }, { "@type": "Question", "name": "Les complications sont-elles observées dans les groupes témoins ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Les complications peuvent être observées, mais elles ne sont pas dues au traitement expérimental." } }, { "@type": "Question", "name": "Comment les complications sont-elles analysées ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Elles sont analysées en comparant leur fréquence entre le groupe témoin et le groupe traité." } }, { "@type": "Question", "name": "Les groupes témoins aident-ils à identifier des facteurs de risque ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils permettent de comparer les facteurs de risque entre les groupes traité et témoin." } }, { "@type": "Question", "name": "Comment les facteurs de risque sont-ils évalués ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Ils sont évalués par des questionnaires et des analyses statistiques dans les deux groupes." } } ] } ] }

Sources (10000 au total)

Exploring the molecular mechanism of ginseng against anthracycline-induced cardiotoxicity based on network pharmacology, molecular docking and molecular dynamics simulation.

Previous clinical and basic studies have revealed that ginseng might have cardioprotective properties against anthracycline-induced cardiotoxicity (AIC). However, the underlying mechanism of ginseng a... Fourteen drug-disease common targets were identified. Enrichment analysis showed that the AGE-RAGE in diabetic complications, fluid shear stress and atherosclerosis, and TNF signaling pathway were pot... This study suggested that ginseng might exert their protective effects against AIC through the derived effector compounds beta-Sitosterol, Kaempferol and Fumarine by targeting CCNA2, STAT1, and ICAM1,...

Study of the antidiabetic mechanism of berberine compound on FOXO1 transcription factor through molecular docking and molecular dynamics simulations.

Diabetes mellitus (DM) is a metabolic disorder disease that causes hyperglycemia conditions and associated with various chronic complications leading to mortality. Due to high toxicity of conventional... Docking between ligand and FOXO1 receptor was carried out with Autodock4.2. For molecular dynamics simulations, the force fields of DNA.OL15, protein.ff14SB, gaff2, and tip3p were used....

Research advances of molecular docking and molecular dynamic simulation in recognizing interaction between muscle proteins and exogenous additives.

During storage and processing, muscle proteins, e.g. myosin and myoglobin, will inevitably undergo degeneration, which is thus accompanied by quality deterioration of muscle foods. Some exogenous addi...

Discovery of Highly Potent CRBN Ligands and Insight into Their Binding Mode through Molecular Docking and Molecular Dynamics Simulations.

Cereblon (CRBN) is a substrate receptor of E3 ubiquitin ligase as well as the target of thalidomide and lenalidomide, plays a vital role in endogenous protein degradation. In this article, two series ...

QSAR Study, Molecular Docking and Molecular Dynamic Simulation of Aurora Kinase Inhibitors Derived from Imidazo[4,5-

Cancer is a serious threat to human life and social development and the use of scientific methods for cancer prevention and control is necessary. In this study, HQSAR, CoMFA, CoMSIA and TopomerCoMFA m...

Molecular modelling on multiepitope-based vaccine against SARS-CoV-2 using immunoinformatics, molecular docking, and molecular dynamics simulation.

The pandemic of COVID-19 caused by SARS-CoV-2 has made a worldwide health emergency. Despite the fact that current vaccines are readily available, several SARSCoV-2 variants affecting the existing vac...

In silico molecular targets, docking, dynamics simulation and physiologically based pharmacokinetics modeling of oritavancin.

Oritavancin is a semi-synthetic lipoglycopeptide antibiotic primarily used to treat serious infections caused by Gram-positive bacteria. The aim of this study was to elucidate possible molecular targe... Computational methods were used in this study which include target prediction, molecular docking, molecular dynamics simulation, pharmacokinetics prediction, and physiological-based pharmacokinetics (... Oritavancin was moderately soluble in water and did not permeate the blood-brain barrier. Seven molecular targets were identified in humans. Molecular docking results showed highest binding affinity o... This comprehensive computational study has provided invaluable insights into the pharmacological profile of Oritavancin, aiding its further development and optimization for clinical use....